YU38599A - Nimesulidni gelni sistemi za topikalnu primenu - Google Patents
Nimesulidni gelni sistemi za topikalnu primenuInfo
- Publication number
- YU38599A YU38599A YU38599A YU38599A YU38599A YU 38599 A YU38599 A YU 38599A YU 38599 A YU38599 A YU 38599A YU 38599 A YU38599 A YU 38599A YU 38599 A YU38599 A YU 38599A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- topical use
- gel systems
- nimesulide
- nimesulide gel
- formulations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
Abstract
Predmetni pronalazak se odnosi na nimesulidne formulacije koje obuhvataju karboksivinil polimer koji je neutralisan kao agens za formiranje gela ili poliakrilamid-izoparafin i rastvarač koji se bira iz grupe koju čine etanol, izopropanol i dietilen glikol monoetil etar i na postupak za njegovo dobijanje. Pomenute formulacije imaju niz prednosti u odnosu na postojeće formulacije, takvih kao što su viša stabilnost sistema i bolja bioraspoloživost aktivnog sastojka.[The present invention relates to nimesulide topical formulations comprising a carboxyvinylpolymer neutralized as a gel-forming agent or a polyacrylamide-isoparaffin and a solvent selected from the group consisting of ethanol, isopropanol and diethylene glycol monoethyl ether, and to the process for the preparation thereof. Said formulations have advantages such as higher stability of the system and bioavailability of the active ingredient.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT97MI000408A IT1289973B1 (it) | 1997-02-25 | 1997-02-25 | Sistemi gelificati di nimesulide per uso topico |
Publications (2)
Publication Number | Publication Date |
---|---|
YU38599A true YU38599A (sh) | 2002-06-19 |
RS49700B RS49700B (sr) | 2007-12-31 |
Family
ID=11376173
Country Status (33)
Country | Link |
---|---|
US (2) | US20020119997A1 (sh) |
EP (1) | EP0971708B1 (sh) |
JP (1) | JP2001513093A (sh) |
KR (1) | KR100413143B1 (sh) |
CN (1) | CN1148174C (sh) |
AT (1) | ATE210437T1 (sh) |
AU (1) | AU723843B2 (sh) |
BG (1) | BG64664B1 (sh) |
BR (1) | BR9807729A (sh) |
CA (1) | CA2279277A1 (sh) |
CU (1) | CU22836A3 (sh) |
CZ (1) | CZ293665B6 (sh) |
DE (2) | DE69802913T2 (sh) |
DK (1) | DK0971708T3 (sh) |
EE (1) | EE04041B1 (sh) |
ES (1) | ES2169506T3 (sh) |
GE (1) | GEP20022628B (sh) |
HK (1) | HK1025265A1 (sh) |
HU (1) | HU226122B1 (sh) |
ID (1) | ID22668A (sh) |
IL (1) | IL131128A (sh) |
IS (1) | IS2090B (sh) |
IT (1) | IT1289973B1 (sh) |
MX (1) | MXPA99007468A (sh) |
NO (1) | NO994040L (sh) |
PL (1) | PL190603B1 (sh) |
PT (1) | PT971708E (sh) |
RS (1) | RS49700B (sh) |
RU (1) | RU2181285C2 (sh) |
SK (1) | SK284809B6 (sh) |
TR (1) | TR199902034T2 (sh) |
UA (1) | UA50807C2 (sh) |
WO (1) | WO1998037879A1 (sh) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU718356B2 (en) * | 1998-01-12 | 2000-04-13 | Panacea Biotec Limited | A parenteral water-miscible non-intensely coloured injectable composition of non-steroidal anit-inflammatory drugs |
GB2340751B (en) * | 1998-08-12 | 2003-11-05 | Edko Trading Representation | Pharmaceutical compositions |
AU1888900A (en) * | 1999-05-31 | 2000-12-18 | Shashikant Prabhudas Kurani | A novel formulation of n-(4-nitro-2-phenoxyphenyl)methanesulfonamide |
US8980290B2 (en) | 2000-08-03 | 2015-03-17 | Antares Pharma Ipl Ag | Transdermal compositions for anticholinergic agents |
US7198801B2 (en) | 2000-08-03 | 2007-04-03 | Antares Pharma Ipl Ag | Formulations for transdermal or transmucosal application |
ES2222817B1 (es) * | 2003-07-25 | 2007-03-01 | Luis Ucelay Sanz | Gel frio. |
ATE534373T1 (de) | 2003-10-10 | 2011-12-15 | Antares Pharma Ipl Ag | Transdermale pharmazeutische formulierung zur minimierung von rückständen auf der haut |
WO2006125642A1 (en) | 2005-05-27 | 2006-11-30 | Antares Pharma Ipl Ag | Methods and apparatus for transdermal or transmucosal application of testosterone |
CN101426475A (zh) | 2006-04-21 | 2009-05-06 | 安塔雷斯制药Ipl股份公司 | 使用用于经皮或经粘膜应用的制剂治疗热潮红的方法 |
TR200906775A1 (tr) * | 2009-09-02 | 2011-03-21 | Sanovel İlaç San.Ve Ti̇c.A.Ş. | Nimesulid ve kas gevşetici kombinasyonları |
CN102068404A (zh) * | 2009-11-25 | 2011-05-25 | 中国人民武装警察部队医学院 | 一种尼美舒利温度敏感水凝胶及其制备方法 |
UA121985C2 (uk) * | 2015-01-23 | 2020-08-25 | Др. Редді'З Лабораторіз Лімітед | Нефарбуюча гелева композиція для місцевого застосування, яка містить німесулід |
RU2593777C1 (ru) * | 2015-04-20 | 2016-08-10 | Общество с ограниченной ответственностью "Трейдсервис" | Гелевая форма нимесулида, обладающая противовоспалительным и анальгетическим действием |
CN108158993A (zh) * | 2018-01-12 | 2018-06-15 | 连云港本草美汇医药科技有限公司 | 一种祛痘控油微乳凝胶剂及其制备方法与应用 |
WO2022183001A1 (en) * | 2021-02-25 | 2022-09-01 | Alphyn Biologics | Composition for treatment of topical dermatological bacterial skin conditions |
PL244577B1 (pl) | 2021-12-16 | 2024-02-12 | Univ Gdanski | Sole nimesulidu i sposób otrzymywania kryształów soli nimesulidu |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1251838B (it) * | 1991-09-20 | 1995-05-26 | Lpb Ist Farm | Uso della nimesulide nel trattamento della cataratta |
BR9509183A (pt) * | 1994-10-05 | 1997-12-30 | Helsinn Healthcare Sa | Agente antiinflamatório para uso externo |
HUP9601442A3 (en) * | 1995-07-25 | 1999-03-29 | Panacea Biotec Ltd | Nes antinflammatory and analgetic pharmaceutical compositions, containing nimesulid for transdermal use, and process for producing them |
PL183588B1 (pl) * | 1995-10-05 | 2002-06-28 | Helsinn Healthcare Sa | Środek przeciwzapalny do użytku zewnętrznego zawierający nimesulid |
HUP9601443A3 (en) * | 1996-05-29 | 1999-03-29 | Panacea Biotec Ltd | Injectable analgetic pharmaceutical compositions for intramuscular use containing nimesulid, and process for producing them |
IT1291278B1 (it) * | 1996-07-05 | 1999-01-07 | Errekappa Euroterapici S P A | Preparazione farmaceutica a base di nimesulide per uso topico |
-
1997
- 1997-02-25 IT IT97MI000408A patent/IT1289973B1/it active IP Right Grant
-
1998
- 1998-02-20 CN CNB988027364A patent/CN1148174C/zh not_active Expired - Fee Related
- 1998-02-20 CA CA002279277A patent/CA2279277A1/en not_active Abandoned
- 1998-02-20 PT PT98910713T patent/PT971708E/pt unknown
- 1998-02-20 JP JP53727798A patent/JP2001513093A/ja not_active Ceased
- 1998-02-20 ID IDW990895A patent/ID22668A/id unknown
- 1998-02-20 US US09/380,044 patent/US20020119997A1/en not_active Abandoned
- 1998-02-20 PL PL98335141A patent/PL190603B1/pl not_active IP Right Cessation
- 1998-02-20 DE DE69802913T patent/DE69802913T2/de not_active Expired - Lifetime
- 1998-02-20 EE EEP199900355A patent/EE04041B1/xx not_active IP Right Cessation
- 1998-02-20 WO PCT/EP1998/000990 patent/WO1998037879A1/en active IP Right Grant
- 1998-02-20 HU HU0001486A patent/HU226122B1/hu not_active IP Right Cessation
- 1998-02-20 UA UA99084652A patent/UA50807C2/uk unknown
- 1998-02-20 AU AU64992/98A patent/AU723843B2/en not_active Ceased
- 1998-02-20 IL IL13112898A patent/IL131128A/xx not_active IP Right Cessation
- 1998-02-20 BR BR9807729-5A patent/BR9807729A/pt not_active Application Discontinuation
- 1998-02-20 RS YUP-385/99A patent/RS49700B/sr unknown
- 1998-02-20 RU RU99120392/14A patent/RU2181285C2/ru not_active IP Right Cessation
- 1998-02-20 MX MXPA99007468A patent/MXPA99007468A/es active IP Right Grant
- 1998-02-20 DE DE0971708T patent/DE971708T1/de active Pending
- 1998-02-20 ES ES98910713T patent/ES2169506T3/es not_active Expired - Lifetime
- 1998-02-20 DK DK98910713T patent/DK0971708T3/da active
- 1998-02-20 TR TR1999/02034T patent/TR199902034T2/xx unknown
- 1998-02-20 KR KR10-1999-7007621A patent/KR100413143B1/ko not_active IP Right Cessation
- 1998-02-20 EP EP98910713A patent/EP0971708B1/en not_active Expired - Lifetime
- 1998-02-20 CZ CZ19992986A patent/CZ293665B6/cs not_active IP Right Cessation
- 1998-02-20 GE GEAP19984969A patent/GEP20022628B/en unknown
- 1998-02-20 AT AT98910713T patent/ATE210437T1/de not_active IP Right Cessation
- 1998-02-20 SK SK1141-99A patent/SK284809B6/sk not_active IP Right Cessation
-
1999
- 1999-07-30 IS IS5143A patent/IS2090B/is unknown
- 1999-08-10 BG BG103645A patent/BG64664B1/bg unknown
- 1999-08-20 NO NO994040A patent/NO994040L/no not_active Application Discontinuation
- 1999-08-23 CU CU1999117A patent/CU22836A3/es not_active IP Right Cessation
-
2000
- 2000-07-27 HK HK00104697A patent/HK1025265A1/xx not_active IP Right Cessation
-
2002
- 2002-09-26 US US10/254,862 patent/US7186755B2/en not_active Expired - Fee Related
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