YU1001A - Poliketidi, postupci i materijali za njihovo dobijanje - Google Patents
Poliketidi, postupci i materijali za njihovo dobijanjeInfo
- Publication number
- YU1001A YU1001A YU1001A YU1001A YU1001A YU 1001 A YU1001 A YU 1001A YU 1001 A YU1001 A YU 1001A YU 1001 A YU1001 A YU 1001A YU 1001 A YU1001 A YU 1001A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- nucleic acid
- polylinker
- plasmids
- encoding
- polyketides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
- C12P19/623—Avermectin; Milbemycin; Ivermectin; C-076
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Seasonings (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
Molekuli nukleinske kiseline koji kodiraju makar deo poliketid sintetaze tipa I i poseduju polilinker sa višestrukim restrikcionim mestima na mestu jednog ili više PKS gena koji kodiraju enzime vezane za redukciju, dalje opcionalno sadrže nukleinsku kiselinu koja je ubačena u polilinker, zatim nukleinska kiselina koja kodira jedan ili više reduktivnih enzima; plazmidi u koje su ubačene ovakve nukleinske kiseline; domaćinske ćelije transfektovane sa ovakvim plazmidima; metode vezane za to. [Nucleic acid molecules encoding at least part of a Type I polyketide synthase, and having a polylinker with multiple restriction enzyme sites in place of one or more PKS genes encoding enzymes associated with reduction, optionally further including nucleic acid incorporated into the polylinker, the further nucleic acid encoding one or more reductive enzymes; plasmids incorporating such nucleic acids; host cells transfected with such plasmids; methods relating thereto.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9814622.8A GB9814622D0 (en) | 1998-07-06 | 1998-07-06 | Polyketides,their preparation,and materials for use therein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU1001A true YU1001A (sh) | 2003-04-30 |
Family
ID=10835024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU1001A YU1001A (sh) | 1998-07-06 | 1999-07-06 | Poliketidi, postupci i materijali za njihovo dobijanje |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7001747B1 (sh) |
| EP (1) | EP1095147B1 (sh) |
| JP (1) | JP2002519066A (sh) |
| KR (1) | KR20010074652A (sh) |
| CN (1) | CN1316002A (sh) |
| AT (1) | ATE321138T1 (sh) |
| AU (1) | AU762185B2 (sh) |
| BR (1) | BR9911898B1 (sh) |
| CA (1) | CA2332491A1 (sh) |
| CZ (1) | CZ200123A3 (sh) |
| DE (1) | DE69930515T2 (sh) |
| GB (1) | GB9814622D0 (sh) |
| HK (1) | HK1034535A1 (sh) |
| HU (1) | HUP0105464A2 (sh) |
| ID (1) | ID27760A (sh) |
| IL (1) | IL140439A0 (sh) |
| MX (1) | MXPA00012894A (sh) |
| NZ (1) | NZ509602A (sh) |
| PL (1) | PL345851A1 (sh) |
| TR (1) | TR200100027T2 (sh) |
| WO (1) | WO2000001827A2 (sh) |
| YU (1) | YU1001A (sh) |
| ZA (1) | ZA200100775B (sh) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000245457A (ja) | 1999-02-24 | 2000-09-12 | Kitasato Inst:The | エバーメクチンアグリコン合成酵素遺伝子 |
| EP1270728B1 (en) * | 2000-02-24 | 2007-04-18 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing avermectin derivative |
| KR20020012395A (ko) * | 2000-08-07 | 2002-02-16 | 김종하 | 사이버 카드 매매제어방법 |
| AT4929U1 (de) * | 2001-03-29 | 2002-01-25 | Plansee Tizit Ag | Verfahren zur herstellung von hartmetallgranulat |
| US20030225006A1 (en) * | 2002-02-19 | 2003-12-04 | Burns Lesley S | Novel spinosyn-producing polyketide synthases |
| EP2277898A3 (en) | 2002-07-16 | 2011-06-01 | Biotica Technology Limited | Rapamycin analogues |
| US7407941B2 (en) * | 2003-08-26 | 2008-08-05 | Pfizer, Inc. | N-desmethyl-N-substituted-11-deoxyerythromycin compounds |
| GB0327720D0 (en) | 2003-11-28 | 2003-12-31 | Biotica Tech Ltd | Erythromycins and process for their preparation |
| GB0417852D0 (en) | 2004-08-11 | 2004-09-15 | Biotica Tech Ltd | Production of polyketides and other natural products |
| ES2556211T3 (es) | 2008-09-24 | 2016-01-14 | Shanghai Institute Of Organic Chemistry, Chinese Academy Of Sciences | Agrupación de genes novedosa |
| GB0904540D0 (en) | 2009-03-17 | 2009-04-29 | Biotica Tech Ltd | Novel compounds and methods for their production |
| GB0914589D0 (en) | 2009-08-20 | 2009-09-30 | Biotica Tech Ltd | Novel compounds and methods for their production |
| WO2011098805A1 (en) | 2010-02-09 | 2011-08-18 | Biotica Technology Limited | Sanglifehrin based compounds |
| EP2533784B1 (en) | 2010-02-09 | 2015-04-22 | Neurovive Pharmaceutical AB | Sanglifehrin based compounds |
| WO2011098808A1 (en) | 2010-02-09 | 2011-08-18 | Biotica Technology Limited | Sanglifehrin based compounds |
| CN106916836B (zh) * | 2015-12-24 | 2022-08-12 | 武汉合生科技有限公司 | 化合物的生物合成基因簇及其应用 |
| CN106619540A (zh) * | 2016-10-10 | 2017-05-10 | 东莞市麦亘生物科技有限公司 | 一种抗肝癌纳米核酸类冻干粉及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4199569A (en) * | 1977-10-03 | 1980-04-22 | Merck & Co., Inc. | Selective hydrogenation products of C-076 compounds and derivatives thereof |
| DE69023036T2 (de) * | 1989-03-31 | 1996-06-13 | Merck & Co Inc | Klonierung von Streptomyces avermitilis Genen zur Biosynthese von Avermectin und Verfahren zu ihrer Verwendung. |
| NZ240150A (en) * | 1990-10-15 | 1993-07-27 | Merck & Co Inc | Fermentation medium and its use in the production of ivermectin derivatives |
| WO1998001546A2 (en) * | 1996-07-05 | 1998-01-15 | Biotica Technology Limited | Polyketides and their synthesis |
| GB9814006D0 (en) * | 1998-06-29 | 1998-08-26 | Biotica Tech Ltd | Polyketides and their synthesis |
-
1998
- 1998-07-06 GB GBGB9814622.8A patent/GB9814622D0/en not_active Ceased
-
1999
- 1999-07-06 US US09/743,162 patent/US7001747B1/en not_active Expired - Lifetime
- 1999-07-06 DE DE69930515T patent/DE69930515T2/de not_active Expired - Lifetime
- 1999-07-06 EP EP99929580A patent/EP1095147B1/en not_active Expired - Lifetime
- 1999-07-06 HU HU0105464A patent/HUP0105464A2/hu unknown
- 1999-07-06 WO PCT/GB1999/002158 patent/WO2000001827A2/en active IP Right Grant
- 1999-07-06 AU AU46365/99A patent/AU762185B2/en not_active Ceased
- 1999-07-06 KR KR1020017000136A patent/KR20010074652A/ko not_active Application Discontinuation
- 1999-07-06 TR TR2001/00027T patent/TR200100027T2/xx unknown
- 1999-07-06 CA CA002332491A patent/CA2332491A1/en not_active Abandoned
- 1999-07-06 NZ NZ509602A patent/NZ509602A/en unknown
- 1999-07-06 IL IL14043999A patent/IL140439A0/xx unknown
- 1999-07-06 PL PL99345851A patent/PL345851A1/xx not_active Application Discontinuation
- 1999-07-06 MX MXPA00012894A patent/MXPA00012894A/es not_active IP Right Cessation
- 1999-07-06 BR BRPI9911898-0A patent/BR9911898B1/pt not_active IP Right Cessation
- 1999-07-06 AT AT99929580T patent/ATE321138T1/de not_active IP Right Cessation
- 1999-07-06 CZ CZ200123A patent/CZ200123A3/cs unknown
- 1999-07-06 ID IDW20010275A patent/ID27760A/id unknown
- 1999-07-06 JP JP2000558217A patent/JP2002519066A/ja active Pending
- 1999-07-06 YU YU1001A patent/YU1001A/sh unknown
- 1999-07-06 CN CN99810270A patent/CN1316002A/zh active Pending
-
2001
- 2001-01-26 ZA ZA200100775A patent/ZA200100775B/en unknown
- 2001-07-16 HK HK01104953A patent/HK1034535A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PL345851A1 (en) | 2002-01-14 |
| CA2332491A1 (en) | 2000-01-13 |
| GB9814622D0 (en) | 1998-09-02 |
| NZ509602A (en) | 2003-12-19 |
| DE69930515D1 (de) | 2006-05-11 |
| JP2002519066A (ja) | 2002-07-02 |
| WO2000001827A2 (en) | 2000-01-13 |
| TR200100027T2 (tr) | 2001-07-23 |
| HUP0105464A2 (hu) | 2002-04-29 |
| ZA200100775B (en) | 2001-11-05 |
| ATE321138T1 (de) | 2006-04-15 |
| HK1034535A1 (en) | 2001-10-26 |
| DE69930515T2 (de) | 2006-12-14 |
| CN1316002A (zh) | 2001-10-03 |
| EP1095147A2 (en) | 2001-05-02 |
| BR9911898A (pt) | 2001-03-27 |
| AU762185B2 (en) | 2003-06-19 |
| AU4636599A (en) | 2000-01-24 |
| EP1095147B1 (en) | 2006-03-22 |
| US7001747B1 (en) | 2006-02-21 |
| WO2000001827A3 (en) | 2000-04-27 |
| CZ200123A3 (cs) | 2001-12-12 |
| IL140439A0 (en) | 2002-02-10 |
| MXPA00012894A (es) | 2002-07-02 |
| KR20010074652A (ko) | 2001-08-04 |
| ID27760A (id) | 2001-04-26 |
| BR9911898B1 (pt) | 2010-11-30 |
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