WO2022165700A1 - 一种多肽营养粉及其制备方法 - Google Patents

一种多肽营养粉及其制备方法 Download PDF

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WO2022165700A1
WO2022165700A1 PCT/CN2021/075238 CN2021075238W WO2022165700A1 WO 2022165700 A1 WO2022165700 A1 WO 2022165700A1 CN 2021075238 W CN2021075238 W CN 2021075238W WO 2022165700 A1 WO2022165700 A1 WO 2022165700A1
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powder
vitamin
peptide
protein
acetate
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PCT/CN2021/075238
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English (en)
French (fr)
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吴达镕
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吴达镕
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Priority to PCT/CN2021/075238 priority Critical patent/WO2022165700A1/zh
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/185—Vegetable proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/19—Dairy proteins

Definitions

  • the invention relates to a polypeptide nutritional powder and a preparation method thereof.
  • the first stage is the belief that proteins are broken down into amino acids and oligopeptides in the stomach and intestines, which opened up the history of peptide nutrition.
  • the second stage is that people find that the type of peptide is related to the structure of the peptide chain, and the shorter the peptide chain, the easier it is to be absorbed by the body, which lays the foundation of peptide nutrition.
  • the third stage is the discovery that dipeptide and tripeptide compounds are absorbed faster in the body than amino acids, which fully demonstrates the necessity of drinking peptides.
  • the digestion of protein is mainly divided into two stages.
  • the first stage is in the stomach, where the protein is decomposed into amino acids and oligopeptides.
  • the second stage is that the undigested protein is absorbed into the small intestinal mucosal cell membrane and cytoplasm for digestion.
  • the final decomposition products are amino acids and small peptides, which enter the blood in the form of amino acids and small peptides, and are transported to various parts of the body along with the blood circulation to participate in various life activities, thereby ensuring the health of the body. Therefore, it is an inevitable result that proteins enter the body and break down into small peptides.
  • the oligopeptide obtained by enzymatic hydrolysis technology is to decompose the protein into peptide fragments outside the body, and then take it directly, which means that the decomposition process of the protein is carried out in vitro, and then absorbed by the human body, saving the protein in the body. digestive process.
  • Small molecule peptides mainly control the growth, development, immune regulation and metabolism of the human body. They are in a state of balance in the human body. If the active peptides are reduced, the function of the human body will undergo important changes. For children, his growth and development become Slow, or even stop, a dwarf will be formed in the long run.
  • active peptides For adults or the elderly, lack of active peptides will cause their own immunity to decline, metabolic disorders, endocrine disorders, and cause various diseases, such as insomnia and body weight loss. or bloated. Since the active peptides also act on the nervous system, the human body will become sluggish, the mind will no longer be intelligent, and more importantly, the active peptides will decrease, which directly causes the gradual aging of all parts of the human body and causes various diseases.
  • Peptide technology realizes the transformation of end products. It is rich in small molecule active peptides and various nutrients, which can quickly replenish energy and restore the physical strength of strong physical exhaustion. It plays an important role in eliminating fatigue, enhancing physical fitness and physical fitness, improving overall health, and enhancing disease resistance. It is especially suitable for people with poor immunity, poor gastrointestinal function, early recovery from serious illness, recovery period after surgery, work intensity or pressure and need to relieve fatigue; athletes and army soldiers need to quickly recover their physical strength.
  • the purpose of the present invention is to rapidly replenish energy, restore physical energy, supplement the consumption of nutrients, and achieve the effect of improving immunity by taking a polypeptide nutritional powder.
  • a nutritional powder is composed of soybean protein isolate, soybean peptide powder, whey protein powder, collagen peptide powder, marine fish oligopeptide powder, wheat peptide, non-dairy fat powder (glucose syrup, hydrogenated vegetable oil, Casein, Dipotassium Phosphate, Mono- and Diglyceride Fatty Acids, Silicon Dioxide), Maltodextrin, Whole Milk Powder, Zinc Gluconate, Calcium Hydrogen Phosphate, Magnesium Carbonate, Ferric Pyrophosphate, Vitamin A Acetate, Vitamin D3 , dl-alpha-tocopherol acetate, thiamine hydrochloride, riboflavin, pyridoxine hydrochloride, hydrocobalamin, L-ascorbic acid, niacin, folic acid, calcium D-pantothenate, xanthan gum, aspartame ( Nutritious food prepared from phenylpropionic acid) and edible essence.
  • Vitamin A acetate 400 ⁇ 1700ug
  • the preferred weight proportioning range of the present invention is:
  • Vitamin A acetate 400 ⁇ 1500ug
  • the optimum weight ratio range of the present invention is:
  • Vitamin A acetate 500ug
  • the above-mentioned polypeptide nutritional powder is characterized in that the raw materials also include adding 80 mg of aspartame (containing phenylalanine) and 0.1 g of cocoa essence to form cocoa flavor.
  • the above-mentioned polypeptide nutritional powder is characterized in that the raw materials further include adding 80 mg of aspartame (containing phenylalanine) and 0.1 g of almond essence to form an almond flavor.
  • the above-mentioned preparation method of a polypeptide nutritional powder is characterized in that the raw materials are weighed according to the above-mentioned raw material ratio, initially mixed, passed through an 80-mesh sieve, added to a mixer and mixed for 1-3 hours, and sterilized in a microwave sterilizer for 1-1 hours. Within hours, the finished product will be obtained after being put into a bag for inspection.
  • the above-mentioned preparation method of a polypeptide nutritional powder is also characterized in that the finished dosage form is any dosage form made by adopting a food acceptable carrier or excipient, such as powder, granule, tablet, capsule and the like.
  • soybean protein isolate The protein content of soybean protein isolate is more than 90%, there are nearly 20 kinds of amino acids, and it contains essential amino acids for human body. It is rich in nutrients and does not contain cholesterol. It is one of the few varieties of vegetable protein that can replace animal protein. Studies have shown that taking 25g of soy protein daily can effectively reduce the levels of total cholesterol and LDL cholesterol in the human blood, thereby reducing the risk of heart disease.
  • soybean peptide powder can boost protein, lower blood pressure, blood lipids and cholesterol. It can regulate blood sugar, promote blood circulation, and reduce lipids. It can improve the absorption and digestion function of the human body, and improve the structure of the small intestine. It can moisten the intestines and laxatives, improve liver function, and has the effect of nourishing the liver and protecting the liver. Anti-fatigue, enhance resistance and immunity. Antioxidant and moisturizing. It can also promote energy metabolism and has the function of losing weight.
  • Whey protein powder can provide the amino acids required for the body's metabolism, and the amino acid ratio structure and functional properties are similar to human milk. It can help improve the function of the immune system and enhance the resistance. Regulates the body's water and electrolyte balance and enhances the body's ability to resist fatigue.
  • Collagen peptides can effectively supplement collagen in the body, and can play a role in beauty and anti-aging. It is rich in amino acids, which can be quickly absorbed by the body and can play a role in promoting digestion and absorption in the gastrointestinal tract. Collagen peptides are smaller molecules that can enter cells and can be restorative for patients with wounds. Can also prevent cancer.
  • Marine fish oligopeptides are beneficial and harmless to the body. Its main nutritional functions are to promote body circulation, supplement protein, increase immunity and protect skeletal muscles, and are also very effective in the treatment of gout. When acting on the human body, it can effectively prevent the retention of purine substances in the body by increasing the amount of HPRT enzyme and LDH, reduce the content of uric acid, and dissolve the uric acid crystals in the joints, which is a major milestone in gout research.
  • the above essential components have several major effects: 1. Lowering blood pressure, blood lipids, and blood sugar; promoting the absorption of minerals such as calcium and magnesium; scavenging free radicals; enhancing resistance. Wheat peptides, soybean peptides, and marine fish oligopeptides have the functions of lowering blood pressure, promoting mineral absorption, scavenging free radicals, lowering blood lipids, and enhancing immunity. 2. Promote the repair and growth of gastrointestinal mucosal cells, maintain the integrity of the mucosal structure, and improve the health of the gastrointestinal tract. Because of its unique glutamine structure, wheat peptides can promote the repair and growth of gastrointestinal mucosal cells, maintain the integrity of the mucosal structure, and improve the health of the gastrointestinal tract.
  • soybean peptide can promote the body's protein synthesis, reduce the body's own protein consumption during exercise, and promote the recovery of physical fitness after exercise. 4. Supplement the lost collagen, improve bone health and promote wound healing. Unique marine fish oligopeptides can improve bone health and promote wound healing.
  • Zinc gluconate can improve appetite and skin health, and calcium hydrogen phosphate can effectively maintain bone density and help bones and teeth develop firmly.
  • Magnesium carbonate is an important component of energy metabolism, tissue formation and bone development.
  • Iron pyrophosphate is an important component and essential element for the formation and production of red blood cells.
  • vitamin A acetate can supplement vitamin A to help maintain dark vision
  • vitamin D3 can promote calcium absorption and bone formation
  • dl- ⁇ -tocopherol acetate can supplement vitamin E antioxidant
  • thiamine hydrochloride Riboflavin can supplement vitamin B1 to maintain the normal physiological function of the nervous system
  • riboflavin can supplement vitamin B2 to maintain the health of the skin and mucous membranes, and is an indispensable component of energy metabolism.
  • Pyridoxine hydrochloride contains vitamin B6 which helps in protein metabolism and utilization.
  • Hydrocobalamin can supplement vitamin B12 to help the formation of red blood cells
  • L-ascorbic acid can supplement vitamin C, which is an indispensable ingredient to help maintain skin and mucous membranes, nervous system health, and energy metabolism.
  • Folic acid helps in the formation of red blood cells.
  • Calcium D-pantothenate is an important component of energy metabolism and tissue formation.
  • the present invention uses soybean protein isolate, soybean peptide powder, whey protein powder, collagen peptide powder, marine fish oligopeptide powder, wheat peptide, non-dairy creamer, A high-protein supplement with 26% peptide content and more than 75% total protein from milk powder, multivitamins and minerals. It can quickly replenish energy and restore the physical strength consumed by strong physical strength. It plays an important role in eliminating fatigue, enhancing physical fitness and physical fitness, improving overall health, and enhancing disease resistance. It is especially suitable for people with poor immunity, poor gastrointestinal function, early recovery from serious illness, recovery period after surgery, work intensity or pressure and need to relieve fatigue; athletes and army soldiers need to quickly recover their physical strength.
  • Vitamin A acetate 450ug
  • Preparation method The above raw materials are initially mixed, passed through an 80-mesh sieve, added to a mixer and mixed for 1 to 3 hours, sterilized by a microwave sterilizer for 1 hour, and the finished product is obtained after inspection. Excipients are made into any dosage form, such as powders, granules, tablets, capsules, and the like.
  • Vitamin A acetate 1000ug
  • Preparation method The above raw materials are initially mixed, passed through an 80-mesh sieve, added to a mixer and mixed for 1 to 3 hours, sterilized by a microwave sterilizer for 1 hour, and the finished product is obtained after inspection. Excipients are made into any dosage form, such as powders, granules, tablets, capsules, and the like.
  • Vitamin A acetate 500ug
  • Preparation method The above raw materials are initially mixed, passed through an 80-mesh sieve, added to a mixer and mixed for 1 to 3 hours, sterilized by a microwave sterilizer for 1 hour, and the finished product is obtained after inspection. Excipients are made into any dosage form, such as powders, granules, tablets, capsules, and the like.
  • Vitamin A acetate 500ug
  • Preparation method The above raw materials are initially mixed, passed through an 80-mesh sieve, added to a mixer and mixed for 1 to 3 hours, sterilized by a microwave sterilizer for 1 hour, and the finished product is obtained after inspection. Excipients are made into any dosage form, such as powders, granules, tablets, capsules, and the like.
  • Vitamin A acetate 500ug
  • Preparation method The above raw materials are initially mixed, passed through an 80-mesh sieve, added to a mixer and mixed for 1 to 3 hours, sterilized by a microwave sterilizer for 1 hour, and the finished product is obtained after inspection. Excipients are made into any dosage form, such as powders, granules, tablets, capsules, and the like.
  • this polypeptide nutritional powder contains daidzein, which can regulate endocrine, as well as a variety of collagen, ammonia
  • Base acids and vitamins have a moisturizing effect on the skin.
  • TCM dialectics refer to the diagnostic criteria of the Digestive System Diseases Professional Committee of the Chinese Association of Integrative Medicine in 1989.
  • iii Effective the main symptoms and signs were significantly relieved, the scope of mucosal lesions was reduced by more than 1/2, the inflammation was relieved, and the ulcer surface was reduced; intestinal metaplasia and dysplasia were relieved;
  • the treatment group was given the polypeptide nutritional powder of the present invention, 3 times a day, 20 g of warm water and 200 ml of warm water each time, one month as a course of treatment, severe disease can last for 2-3 months, and all drugs for strengthening the spleen and nourishing the stomach were stopped during the observation period.
  • the gastroscope and various physical and chemical examinations were reviewed once, and the results were as follows:
  • this polypeptide nutritional powder can quickly restore physical fitness, enhance the immunity and endurance of high-intensity laborers and exercisers, and at the same time have a significant effect on gastric motility.

Abstract

一种多肽营养粉及其制备方法。它是由大豆分离蛋白、大豆肽粉、乳清蛋白粉、胶原蛋白肽粉、海洋鱼低聚肽粉、小麦肽、植脂末(葡萄糖浆、氢化植物油、酪蛋白、磷酸氢二钾、单、双甘油脂肪酸脂、二氧化硅)、麦芽糊精、全脂乳粉、葡萄糖酸锌、磷酸氢钙、碳酸镁、焦磷酸铁、醋酸维生素A、维生素D 3、dl-α-醋酸生育酚、盐酸硫胺素、核黄素、盐酸吡哆醇、氢钴胺、L-抗坏血酸、烟酸、叶酸、D-泛酸钙、黄原胶、阿斯巴甜(含苯丙氢酸)、食用香精而组成的营养食品。所述营养粉能够快速补充适用于人体的蛋白质营养，增强体质，产生免疫抗体，增强抵抗外来细菌病毒侵袭患人体的能力。特别适合免疫力差人群；肠胃功能不好人群；大病初愈及手术后恢复期人群；工作强度或压力大需要缓解疲劳的人群；运动员和部队战士需要快速恢复体力人群。

Description

一种多肽营养粉及其制备方法 技术领域
本发明涉及一种多肽营养粉及其制备方法。
 背景技术
现代科学研究证明，蛋白质是人体中重要的营养物质，是生命活动的基础，没有蛋白质就没有生命，所以，人体必须从外界获取蛋白质，才能保证机体的新陈代谢。大自然或人体中的蛋白质种类非常多，不同的蛋白质进入机体后会被运输到各个部位，参与不同的生命活动。这是因为蛋白质属于大分子物质，研究发现，人的肠道无法直接吸收利用从外界摄入的蛋白质，肠道只能吸收小分子肽段结构或氨基酸结构的营养物质，因为这些营养物质的分子量小。而蛋白质进入机体后是以小分子肽及氨基酸的形式被机体所吸收的，对于蛋白质消化的认知，从“蛋白质进入机体后全部消化为氨基酸”转变为“蛋白质进入机体后部分转化为氨基酸，部分转化为肽段，然后被机体吸收”。而随着人们对这个观点的深入研究，肽在营养学中的概念也愈发地清晰。
人们对肽的认知主要有三个阶段：第一阶段是人们认为蛋白质在肠胃中被分解成氨基酸与低聚肽，这个观点打开了肽营养的历史。第二个阶段是人们发现肽的种类与肽链结构相关，且肽链越短，则越容易被机体所吸收，这奠定了肽营养学的基础。第三个阶段是人们发现二肽及三肽化合物在机体中的吸收速度比氨基酸在机体中的吸收速度快，这充分说明了喝肽的必要性。
蛋白质的消化主要分为两个阶段，一阶段是在肠胃中，蛋白质被分解成氨基酸与低聚肽，第二阶段是未被消化的蛋白质会被吸收到小肠黏膜细胞膜和胞浆内进行消化，最终分解产物为氨基酸和小肽，并以氨基酸和小肽的形式进入血液，随着血液循环被输送到机体的各个部位，参与各种生命活动，从而保证机体的健康。所以，蛋白质进入机体中分解成小肽是不可避免的结果。而通过酶解技术所得到的低聚肽是将蛋白质在机体外分解成肽段，然后直接服用，这等于将蛋白质的分解过程在体外进行，然后再被人体所吸收，节省了蛋白质在体内的消化过程。小分子肽主要控制人体的生长、发育、免疫调节和新陈代谢，它在人体处于一种平衡状态，若活性肽减少后，人体的机能发生重要变化，对于儿童来说，他的生长、发育变得缓慢，甚至停止，长久下去就形成了侏儒，对成年人或老年人，缺少活性肽后，自身的免疫力就会下降，新陈代谢紊乱，内分泌失调，引起各种疾病的产生，如失眠、身体消瘦或浮肿。由于活性肽还作用于神经系统，因此人体就会变得动作迟缓，头脑不再聪慧，更主要的是活性肽减少，直接引起人身体各部位逐渐出现全面衰老，引发各种疾病。
多肽技术实现终端产品转化，富含小分子活性多肽和多种营养成分，能够迅速补充能量，恢复强体力消耗的体力。对消除疲劳，增强体能和身体素质，改善整体健康水平，增强抗病能力有重要作用。特别适合免疫力差、肠胃功能不好、大病初愈及手术后恢复期、工作强度或压力大需要缓解疲劳的人群；运动员和部队战士需迅速恢复体力人群。
 技术问题
本发明的目的是通过服用一种多肽营养粉，能迅速补充能量，恢复体能，补充营养的消耗，并达到提高免疫力的作用。
 技术解决方案
本发明技术方案：一种营养粉它是由大豆分离蛋白、大豆肽粉、乳清蛋白粉、胶原蛋白肽粉、海洋鱼低聚肽粉、小麦肽、植脂末（葡萄糖浆、氢化植物油、酪蛋白、磷酸氢二钾、单、双甘油脂肪酸脂、二氧化硅）、麦芽糊精、全脂乳粉、葡萄糖酸锌、磷酸氢钙、碳酸镁、焦磷酸铁、醋酸维生素A、维生素D³、dl-α-醋酸生育酚、盐酸硫胺素、核黄素、盐酸吡哆醇、氢钴胺、L-抗坏血酸、烟酸、叶酸、D-泛酸钙、黄原胶、阿斯巴甜(含苯丙氢酸)、食用香精制备而成的营养食品。
原料                           重量配比（配方加入量 100G ）
大豆分离蛋白             10~90g
大豆肽粉                    3~15g
乳清蛋白粉                 1~10g
胶原蛋白肽粉             3~15g
海洋鱼低聚肽粉          3~15g
小麦肽                        3~15g
植脂末                        1~50g
麦芽糊精                    1~15g
全脂乳粉                    1~10g
葡萄糖酸锌                 6~18mg
磷酸氢钙                    250~1000mg
碳酸镁                        130~210mg
焦磷酸铁                    9.5~22mg
醋酸维生素A              400~1700ug
维生素D³                    1~2ug
dl-α-醋酸生育酚          7.6~18mg
盐酸硫胺素                 0.9~2.2mg
核黄素                        0.9~2.2mg
盐酸吡哆醇                 0.7~2.2mg
氢钴胺                        1~6.6ug
L-抗坏血酸                 100~225mg
烟酸                           11~33mg
叶酸                           60~600ug
D-泛酸钙                    2.2~8mg
黄原胶                        0~0.9g
本发明优选重量配比范围是：
原料                        重量配比（配方加入量 100G ）
大豆分离蛋白          30~80g
大豆肽粉                 3~10g
乳清蛋白粉                     2~8g
胶原蛋白肽粉          3~10g
海洋鱼低聚肽粉              3~10g
小麦肽                            3~10g
植脂末                            5~20g
麦芽糊精                 5~12g
全脂乳粉                 1~10g
葡萄糖酸锌                     6~18mg
磷酸氢钙                 250~800mg
碳酸镁                            130~200mg
焦磷酸铁                 10~20mg
醋酸维生素A           400~1500ug
维生素D³                 1~2ug
dl-α-醋酸生育酚              7.6~18mg
盐酸硫胺素                     1~2mg
核黄素                            1~2mg
盐酸吡哆醇                     0.7~2.2mg
氢钴胺                            1~6.6ug
L-抗坏血酸                     100~200mg
烟酸                        11~33mg
叶酸                        60~600ug
D-泛酸钙                 2.2~8mg
黄原胶                            0~0.9g
本发明最佳重量配比范围是：
原料                        重量配比（配方加入量 100G ）
大豆分离蛋白             50g
大豆肽粉                    7g
乳清蛋白粉                 5g
胶原蛋白肽粉             7g
海洋鱼低聚肽粉          7g
小麦肽                        5g
植脂末                        10g
麦芽糊精                    5g
全脂乳粉                    3g
葡萄糖酸锌                 15mg
磷酸氢钙                    400mg
碳酸镁                        180mg
焦磷酸铁                    15mg
醋酸维生素A              500ug
维生素D³                    1ug
dl-α-醋酸生育酚          15mg
盐酸硫胺素                 1.5mg
核黄素                        1.8mg
盐酸吡哆醇                 1.5mg
氢钴胺                        2ug
L-抗坏血酸                 180mg
烟酸                           20mg
叶酸                           280ug
D-泛酸钙                    7mg
黄原胶                        0.25g
如上所述的多肽营养粉，其特征在于原料还包括加入80mg 阿斯巴甜（含苯丙氢酸），以及0.1g 可可香精，形成可可味。
如上所述的多肽营养粉，其特征在于原料还包括加入80mg 阿斯巴甜（含苯丙氢酸），以及0.1g 杏仁香精，形成杏仁味。
如上所述的一种多肽营养粉的制备方法，其特征在于按上述原料配比称取原料，经初混，过80 目筛，加入混合机中混合1-3 小时，微波杀菌器中杀菌1 小时，入袋装检验后即得成品。
如上所述的一种多肽营养粉的制备方法，其特征还在于成品剂型是采用食品上可接受的载体或赋形剂制成的任何剂型，如粉剂、颗粒剂、片剂、胶囊剂等。
本发明的优点在于以下必须的组分是各种动、植物优质蛋白来源：
大豆分离蛋白中蛋白质含量在90%以上，氨基酸种类有近20 种，并含有人体必需氨基酸，营养丰富且不含胆固醇，是植物蛋白中为数不多的可替代动物蛋白的品种之一。研究显示，每日服用25g 大豆蛋白可有效降低人体血液中总胆固醇和低密度脂蛋白胆固醇的含量，从而降低患心脏病的风险。
大豆肽粉中蛋白结构与人体更加接近，最适合我们人体使用。大豆肽粉可以促进蛋白质，降低血压，血脂和胆固醇。可以调节血糖，促进血液循环，脂质谢。可以改善人体的吸收及消化功能，改善小肠组织结构。可以润肠通便，改善肝脏功能，有养肝护肝的作用。可以抗疲劳，增强抵抗力及免疫力。可以抗氧化，还有保湿的作用。还可以促进能量代谢，有减肥功能。
乳清蛋白粉可以提供身体新陈代谢所需的氨基酸，且氨基酸比例结构方面，以及在功能特性上与人乳都相似。可帮助完善免疫系统功能，增强抵抗力。调节体内的水分、电解质平衡，增强机体抗疲劳能力。
胶原蛋白肽可有效补充体内胶原蛋白，可以起到美容养颜、抗衰老的作用。含有丰富的氨基酸，可以快速被体内吸收，能起到促进胃肠道消化吸收的作用。胶原蛋白肽分子较小，可进入细胞中，对有伤口的患者来说可以起到恢复作用。亦可防癌。
海洋鱼低聚肽对身体有益无害，其主要营养作用是促进身体循环、补充蛋白、增加免疫和保护骨骼肌肉，而对于治疗痛风也是很有效果。作用于人体时，是通过增加HPRT 酵素与LDH 数量有效地阻止嘌呤物质在体内的滞留，降低尿酸含量，溶解关节处的尿酸结晶，是痛风研究的一大里程碑。
以上必须组分有几大功效：1、降血压、血脂、血糖;促进钙镁等矿物质的吸收;清除自由基;增强抵抗力。小麦肽、大豆肽、海洋鱼低聚肽都有降血压、促进矿物质吸收、清除自由基、降血脂、增强免疫力等作用。2、促进胃肠道粘膜细胞的修复和生长,维护粘膜结构的完整,改善胃肠的健康状况。小麦肽因特有的谷氨酰胺结构,能够促进胃肠道粘膜细胞的修复和生长,维护黏膜结构完整,改善胃肠的健康状况3、减少运动过程中机体自身蛋白质的消耗;促进运动后体能的恢复。大豆肽因良好的氨基酸平衡模式,能够促进机体蛋白质合成,减少运动过程中机体自身蛋白质的消耗,促进运动后体能的恢复。4、补充人体流失的胶原蛋白,改善骨骼健康,促进伤口愈合。特有的海洋鱼低聚肽可改善骨骼健康,促进伤口愈合。
除了有以上多种优质蛋白质的来源，还增加了多种营养补充剂，葡萄糖酸锌的锌可以改善食欲和皮肤健康，磷酸氢钙可有效维持骨密度，有助于骨骼和牙齿的发育牢固。碳酸镁是能量的代谢、组织形成和骨骼发育的重要成分。焦磷酸铁是血红细胞形成和产生的重要成分和必需元素。
另有各种维生素的添加，醋酸维生素A 可补充维生素A 有助于维持暗视力，维生素D3可以促进钙的吸收和骨骼形成，dl-α-醋酸生育酚可补充维生素E 抗氧化，盐酸硫胺素可补充维生素B1 维持神经系统的正常生理功能，核黄素可补充维生素B2 维持皮肤和粘膜的健康，是能量代谢不可或缺的成分。盐酸吡哆醇含维生素B6 有助于蛋白质的代谢和利用。氢钴胺含可补充维生素B12 有助于红细胞的形成，L-抗坏血酸可补充维生素C，是有助于维持皮肤和粘膜、神经系统健康、能量代谢不可缺少的成分。叶酸有助于红细胞的形成。D-泛酸钙是能量代谢和组织形成的重要成分。
 有益效果
基于小分子肽的诸多优点、加工工艺以及各方面因素，本发明以大豆分离蛋白、大豆肽粉、乳清蛋白粉、胶原蛋白肽粉、海洋鱼低聚肽粉、小麦肽、植脂末、乳粉、复合维生素和矿物质成分制备而成的肽含量达到26 ％，总蛋白质超过75 ％的高蛋白补充食品。能够迅速补充能量，恢复强体力消耗的体力。对消除疲劳，增强体能和身体素质，改善整体健康水平，增强抗病能力有重要作用。特别适合免疫力差、肠胃功能不好、大病初愈及手术后恢复期、工作强度或压力大需要缓解疲劳的人群；运动员和部队战士需迅速恢复体力人群。
 本发明的实施方式
下面以具体实施例对本发明做详细说明：
实施例1
按照下列配比称取原料
原料                          重量配比（配方加入量 100G ）
大豆分离蛋白            1g
大豆肽粉                   5g
乳清蛋白粉                2g
胶原蛋白肽粉            4g
海洋鱼低聚肽粉         4g
小麦肽                       4g
植脂末                       10g
麦芽糊精                   3g
全脂乳粉                   2g
葡萄糖酸锌                7mg
磷酸氢钙                   280mg
碳酸镁                       140mg
焦磷酸铁                   10mg
醋酸维生素A             450ug
维生素D³                   1ug
dl-α-醋酸生育酚        9mg
盐酸硫胺素                1mg
核黄素                       1mg
盐酸吡哆醇                1mg
氢钴胺                       1ug
L-抗坏血酸                110mg
烟酸                          11mg
叶酸                          80ug
D-泛酸钙                   3mg
黄原胶                       0.2g
制备方法: 上述原料经初混，过80 目筛，加入混合机中混合1~3 个小时，微波杀菌器杀菌1 个小时，检验后即得成品，其剂型是采用食品上可以接受的载体或赋形剂制成任何剂型，如粉剂、颗粒剂、片剂、胶囊剂等。
实施例2
按照下列配比称取原料
原料                           重量配比（配方加入量 100G ）
大豆分离蛋白             70g
大豆肽粉                    9g
乳清蛋白粉                 7g
胶原蛋白肽粉             9g
海洋鱼低聚肽粉          9g
小麦肽                        7g
植脂末                        18g
麦芽糊精                    11g
全脂乳粉                    8g
葡萄糖酸锌                 16mg
磷酸氢钙                    600mg
碳酸镁                        200mg
焦磷酸铁                    19mg
醋酸维生素A              1000ug
维生素D³                    2ug
dl-α-醋酸生育酚          17mg
盐酸硫胺素                 2mg
核黄素                        2mg
盐酸吡哆醇                 2mg
氢钴胺                        5.5ug
L-抗坏血酸                 190mg
烟酸                           25mg
叶酸                           450ug
D-泛酸钙                    8mg
黄原胶                        0.8g
制备方法: 上述原料经初混，过80 目筛，加入混合机中混合1~3 个小时，微波杀菌器杀菌1 个小时，检验后即得成品，其剂型是采用食品上可以接受的载体或赋形剂制成任何剂型，如粉剂、颗粒剂、片剂、胶囊剂等。
实施例3
按照下列配比称取原料
原料                           重量配比（配方加入量 100G ）
大豆分离蛋白              50g
大豆肽粉                    7g
乳清蛋白粉                 5g
胶原蛋白肽粉             7g
海洋鱼低聚肽粉          7g
小麦肽                        5g
植脂末                        10g
麦芽糊精                    5g
全脂乳粉                    3g
葡萄糖酸锌                 15mg
磷酸氢钙                    400mg
碳酸镁                        180mg
焦磷酸铁                    15mg
醋酸维生素A              500ug
维生素D³                    1ug
dl-α-醋酸生育酚          15mg
盐酸硫胺素                 1.5mg
核黄素                         1.8mg
盐酸吡哆醇                 1.5mg
氢钴胺                        2ug
L-抗坏血酸                 180mg
烟酸                           20mg
叶酸                           280ug
D-泛酸钙                    7mg
黄原胶                        0.25g
制备方法: 上述原料经初混，过80 目筛，加入混合机中混合1~3 个小时，微波杀菌器杀菌1 个小时，检验后即得成品，其剂型是采用食品上可以接受的载体或赋形剂制成任何剂型，如粉剂、颗粒剂、片剂、胶囊剂等。
实施例4 可可味多肽营养粉
按照下列配比称取原料
原料                    重量配比（总配方加入量 100G ）
大豆分离蛋白                    50g
大豆肽粉                           7g
乳清蛋白粉                        5g
胶原蛋白肽粉                    7g
海洋鱼低聚肽粉                 7g
小麦肽                               5g
植脂末                               10g
麦芽糊精                           5g
全脂乳粉                           3g
葡萄糖酸锌                        15mg
磷酸氢钙                           400mg
碳酸镁                               180mg
焦磷酸铁                           15mg
醋酸维生素A                     500ug
维生素D³                           1ug
dl-α-醋酸生育酚                 15mg
盐酸硫胺素                        1.5mg
核黄素                               1.8mg
盐酸吡哆醇                        1.5mg
氢钴胺                               2ug
L-抗坏血酸                        180mg
烟酸                                  20mg
叶酸                                  280ug
D-泛酸钙                           7mg
黄原胶                               0.25g
阿斯巴甜（含苯丙氢酸）   80mg
可可香精                           0.1g
制备方法: 上述原料经初混，过80 目筛，加入混合机中混合1~3 个小时，微波杀菌器杀菌1 个小时，检验后即得成品，其剂型是采用食品上可以接受的载体或赋形剂制成任何剂型，如粉剂、颗粒剂、片剂、胶囊剂等。
实施例5 杏仁味多肽营养粉
按照下列配比称取原料
原料                                  重量配比（总配方加入量 100G ）
大豆分离蛋白                    50g
大豆肽粉                           7g
乳清蛋白粉                        5g
胶原蛋白肽粉                    7g
海洋鱼低聚肽粉                 7g
小麦肽                               5g
植脂末                               10g
麦芽糊精                           5g
全脂乳粉                           3g
葡萄糖酸锌                        15mg
磷酸氢钙                           400mg
碳酸镁                               180mg
焦磷酸铁                           15mg
醋酸维生素A                     500ug
维生素D³                           1ug
dl-α-醋酸生育酚                 15mg
盐酸硫胺素                        1.5mg
核黄素                               1.8mg
盐酸吡哆醇                        1.5mg
氢钴胺                               2ug
L-抗坏血酸                        180mg
烟酸                                  20mg
叶酸                                  280ug
D-泛酸钙                           7mg
黄原胶                               0.25g
阿斯巴甜（含苯丙氢酸）   80mg
杏仁香精                           0.1g
制备方法: 上述原料经初混，过80 目筛，加入混合机中混合1~3 个小时，微波杀菌器杀菌1 个小时，检验后即得成品，其剂型是采用食品上可以接受的载体或赋形剂制成任何剂型，如粉剂、颗粒剂、片剂、胶囊剂等。
五、实验数据：
5.1 本发明经第三方实验室报告证明营养成分如下：
Figure 918513dest_path_image001
5.2 本发明多肽营养粉对痤疮疗效观察
[观察方法]：
对15 例皮肤科病人进行了10 个月的临床观察，经内服，发现痊愈8 例，占53.3%，好转6 人，占40%，无效1 例，占6.7%。
研究认为本多肽营养粉含大豆黄酮，可调节内分泌，以及多种胶原蛋白、氨
基酸、维生素对皮肤有滋润作用。
5.3 本发明多肽营养粉对胃溃疡疗效观察
[胃溃疡的诊断标准]：按1995 卫生部制定的发布中药新药治疗胃溃疡的临床指导原则。
西医诊断标准:参照1982 年重庆全国胃炎诊治座谈会制定的标准;
中医辩证:参照1989 年中国中西医结合学会消化系统疾病专业委员会的诊断试行标准。
疗效判定标准:按照1995 年卫生部制定发布的中药新药治疗胃溃疡的临床指导原则规定:
i 临床治愈:临床症状体征消失，胃镜复查粘膜慢性炎症好转,肠化生和异型增生恢复正常或消失;
ii 显效:临床主要症状、体征消失,胃镜检查粘膜慢性炎症好转,肠化生和异型增生恢复正常或减轻2 度;
iii 有效:主要症状体征明显减轻,胃镜复查粘膜病变范围缩小1/2 以上,炎症有所减轻,溃疡面减小;肠化生和异型增生减轻;
iv 无效 :达不到有效标准或反恶化。
[治疗方法]:
治疗组给药本发明多肽营养粉，每日3 次,每次20g 温水200 毫升冲服，一个月为一疗程，病情重可连续2-3 个月，观察期间停用一切健脾养胃药物。治疗前后各复查一次胃窥镜及各项理化检查,结果如下:
本发明大豆多肽营养液治疗胃溃疡的总有效率：
Figure 320675dest_path_image002
此表体现出本发明多肽营养粉对胃溃疡总有效率85%，另外其他体征也有显著变化。
5.4 本发明多肽营养粉对运动员体力恢复观察
[观察方法]：
对30 例运动员进行了2 个月的临床观察，每日3 次,每次20g 温水200 毫升冲服。
评价结果
Figure 458396dest_path_image003
研究认为本多肽营养粉可以迅速恢复体能，增强高强度劳动、运动者的免疫力、耐力，同时对胃动力有明显效果。

Claims (7)

  1. 一种多肽营养粉，其特征在于它是由下述重量配比的原料制成的营养食品：大豆分离蛋白10~90g、大豆肽粉3~15g、乳清蛋白粉1~10g、胶原蛋白肽粉3~15g、海洋鱼低聚肽粉3~15g、小麦肽3~15g、植脂末1~50g（葡萄糖浆、氢化植物油、酪蛋白、磷酸氢二钾、单、双甘油脂肪酸脂、二氧化硅）、麦芽糊精1~15g、全脂乳粉1~10g、葡萄糖酸锌6~18mg、磷酸氢钙250~1000mg、碳酸镁130~210mg、焦磷酸铁9.5~22mg、醋酸维生素A 400~1700ug、维生素D³1~2ug、dl-α-醋酸生育酚7.6~18mg、盐酸硫胺素0.9~2.2mg、核黄素0.9~2.2mg、盐酸吡哆醇0.7~2.2mg、氢钴胺1~6.6ug、L-抗坏血酸100~225mg、烟酸11~33mg、叶酸60~600ug、D-泛酸钙2.2~8mg、黄原胶0~0.9g。
  2. 如权利要求1 所述的一种多肽营养粉，其原料的重量配比是：大豆分离蛋白30~80g、大豆肽粉3~10g、乳清蛋白粉2~8g、胶原蛋白肽粉3~10g、海洋鱼低聚肽粉3~10g、小麦肽3~10g、植脂末5~20g（葡萄糖浆、氢化植物油、酪蛋白、磷酸氢二钾、单、双甘油脂肪酸脂、二氧化硅）、麦芽糊精1~12g、全脂乳粉1~10g、葡萄糖酸锌6~18mg、磷酸氢钙250~800mg、碳酸镁130~200mg、焦磷酸铁9.5~20mg、醋酸维生素A 400~1500ug、维生素D³1~2ug、dl-α-醋酸生育酚7.6~18mg、盐酸硫胺素1~2mg、核黄素1~2mg、盐酸吡哆醇0.7~2.2mg、氢钴胺1~6.6ug、L-抗坏血酸100~200mg、烟酸11~33mg、叶酸60~600ug、D-泛酸钙2.2~8mg、黄原胶0~0.9g。
  3. 如权利要求1 或2 所述的一种多肽营养粉，其原料的重量配比是：大豆分离蛋白50g、大豆肽粉7g、乳清蛋白粉5g、胶原蛋白肽粉7g、海洋鱼低聚肽粉7g、小麦肽5g、植脂末10g（葡萄糖浆、氢化植物油、酪蛋白、磷酸氢二钾、单、双甘油脂肪酸脂、二氧化硅）、麦芽糊精5g、全脂乳粉3g、葡萄糖酸锌15mg、磷酸氢钙400mg、碳酸镁180mg、焦磷酸铁15mg、醋酸维生素A 500ug、维生素D³1ug、dl-α-醋酸生育酚15mg、盐酸硫胺素1.5mg、核黄素1.8mg、盐酸吡哆醇1.5mg、氢钴胺2ug、L-抗坏血酸180mg、烟酸20mg、叶酸280ug、D-泛酸钙7mg、黄原胶0.25g。
  4. 如权利要求1 或2 所述的多肽营养粉，其特征在于原料还包括加入80mg 阿斯巴甜（含苯丙氢酸），以及0.1g 可可香精，形成可可味。
  5. 如权利要求1 或2 所述的多肽营养粉，其特征在于原料还包括加入80mg 阿斯巴甜（含苯丙氢酸），以及0.1g 杏仁香精，形成杏仁味。
  6. 如权利要求1~5 所述的一种多肽营养粉配置方法，其特征在于按上市原料的配比称取原料，经初混，经80 目筛，加入混合机混合1~3 个小时，微波杀菌器中杀菌1 个小时，入袋装，检验后即可得成品。
  7. 如权利要求6 所述的一种多肽营养粉的制备方法，其特征在于成品剂型是采用食品上可以接受的载体或赋形制成的粉剂、颗粒剂、片剂、胶囊剂。
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