WO2020085020A1 - Procédé de génération d'hydrate de carbonate de lanthane - Google Patents

Procédé de génération d'hydrate de carbonate de lanthane Download PDF

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Publication number
WO2020085020A1
WO2020085020A1 PCT/JP2019/038872 JP2019038872W WO2020085020A1 WO 2020085020 A1 WO2020085020 A1 WO 2020085020A1 JP 2019038872 W JP2019038872 W JP 2019038872W WO 2020085020 A1 WO2020085020 A1 WO 2020085020A1
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Prior art keywords
carbonate
lanthanum
mol
aqueous solution
minutes
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PCT/JP2019/038872
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English (en)
Japanese (ja)
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千春 前田
浩美 辻
信明 西森
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住友化学株式会社
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Priority to CN201980067496.5A priority Critical patent/CN112867695A/zh
Priority to MX2021004516A priority patent/MX2021004516A/es
Priority to JP2020553034A priority patent/JP7300461B2/ja
Publication of WO2020085020A1 publication Critical patent/WO2020085020A1/fr

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    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
    • C01F17/00—Compounds of rare earth metals

Definitions

  • the present invention relates to a method for producing lanthanum carbonate hydrate.
  • Lanthanum carbonate hydrate is used as a therapeutic agent for hyperphosphatemia in patients with chronic renal failure. It is known that lanthanum carbonate 3-6 hydrate can be produced by reacting an acid that gives a soluble salt of lanthanum with lanthanum oxide and drying the obtained wet cake of lanthanum carbonate octahydrate. (Patent Document 1)
  • lanthanum oxide as a raw material contains elemental impurities such as lead, arsenic, and vanadium, for example, lead is 0.5 ppm or less and arsenic is 1 according to ICH (International Conference on Harmonization of Pharmaceutical Regulations) guidelines for lanthanum carbonate hydrate.
  • ICH International Conference on Harmonization of Pharmaceutical Regulations
  • carbonate is added to an aqueous solution obtained by reacting lanthanum oxide with an acid that gives a soluble salt of lanthanum to adjust the pH of the aqueous solution to 2.9 to 4.5 and remove the solid content produced.
  • a lanthanum carbonate hydrate can be obtained by adjusting the pH to 5.5 to 7 by adding carbonate to the liquid content.
  • the first step is a step of adding a carbonate to an aqueous solution obtained by reacting lanthanum oxide with an acid that gives a soluble salt of lanthanum, and removing a solid content produced.
  • Examples of the acid that gives a soluble salt of lanthanum include hydrochloric acid, nitric acid, and sulfuric acid, and hydrochloric acid is usually used.
  • the amount of the acid used is generally 6 to 10 mol for a monovalent acid and 3 to 5 mol for a divalent acid with respect to 1 mol of lanthanum oxide.
  • This reaction is usually carried out by a method in which an acid is continuously added dropwise, intermittently added, or added all at once to an aqueous suspension of lanthanum oxide.
  • carbonate to the aqueous solution obtained above.
  • the carbonate include sodium carbonate, sodium hydrogen carbonate, potassium carbonate, potassium hydrogen carbonate, ammonium carbonate, and ammonium hydrogen carbonate, and sodium carbonate is usually used.
  • the amount of the carbonate used is generally 0.1 to 0.75 mol in the case of sodium carbonate, potassium carbonate or ammonium carbonate with respect to 1 mol of lanthanum oxide, and the amount of sodium hydrogen carbonate, potassium hydrogen carbonate or ammonium hydrogen carbonate is generally used. Is 0.2 to 1.5 mol.
  • the carbonate may be added dropwise in the form of an aqueous solution. When the amount of acid required to obtain the aqueous solution is excessive, the theoretical amount required for neutralization is added. Thus, the pH of the aqueous solution is adjusted to 2.9 to 4.5, preferably 3.2 to 4.2.
  • the generated solid content is removed by solid-liquid separation operations such as filtration and decantation. Further, it is preferable that the solid content is washed with water, and the washing liquid is added to the liquid content such as the filtrate and the supernatant liquid and then subjected to the second step.
  • the solid content is mainly composed of lanthanum carbonate hydrate and contains elemental impurities derived from lanthanum oxide as a raw material. Seed crystals of lanthanum carbonate hydrate can be added or the temperature can be adjusted to accelerate the precipitation of solids.
  • the temperature for precipitating the solid is usually 1 to 65 ° C., preferably 20 to 30 ° C., and this temperature is maintained, for example, for 5 minutes to 24 hours, preferably for 30 minutes to 4 hours.
  • the second step is to add carbonic acid by adding a carbonate to the liquid obtained in the first step or a liquid obtained by adding a washing liquid to the liquid, if necessary, to give a soluble salt of lanthanum.
  • This is a step of obtaining a lanthanum hydrate. Examples of acids and carbonates that give soluble salts of lanthanum used here are the same as those used in the first step.
  • the amount of the acid used is generally 0 to 0.7 mol for a monovalent acid and 0 to 0.35 mol for a divalent acid with respect to 1 mol of the initial lanthanum oxide.
  • the acid is added by a method such as dripping, intermittently dropping, or adding all at once.
  • the temperature at which the acid is added is usually 1 to 65 ° C, preferably 25 to 55 ° C.
  • Carbonate is added until the pH of the liquid reaches 5.5-7.
  • the temperature at which the carbonate is added is usually 1 to 65 ° C., preferably 25 to 55 ° C., and generally 1 hour to 10 hours, preferably 3 hours to 7 hours.
  • the carbonate may be added dropwise in the form of an aqueous solution.
  • Lanthanum carbonate hydrate precipitates as a result of adding carbonate, but seed crystals of lanthanum carbonate hydrate can be added or the temperature can be adjusted to promote precipitation.
  • the temperature for precipitating the solid is usually 1 to 65 ° C., preferably 25 to 55 ° C., and this temperature is maintained, for example, for 5 minutes to 24 hours, preferably for 30 minutes to 2 hours.
  • the precipitated lanthanum carbonate hydrate can be obtained by solid-liquid separation operations such as filtration and decantation. If necessary, wash with water.
  • the amount of water used for washing is usually 10 to 40 parts by weight, preferably 20 to 30 parts by weight, based on 1 part by weight of the initial lanthanum oxide.
  • the lanthanum carbonate hydrate thus obtained is usually octahydrate, and can be dried to 3 to 6 hydrate by a conventional method.
  • the drying temperature is usually in the range of 20 to 100 ° C.
  • Example 1 Water (3 parts by weight) was added to lanthanum oxide (1 part by weight), the mixture was heated to 40 ° C., 35% hydrochloric acid (a ratio of 6.3 mol to 1 mol of lanthanum oxide) was added dropwise, and a lanthanum chloride aqueous solution was added. Obtained. The liquid temperature during this period was 39 to 52 ° C. A 16.4% sodium carbonate aqueous solution (ratio of 0.22 mol to 1 mol of lanthanum oxide) was added dropwise to the obtained lanthanum chloride aqueous solution at 25 ° C. over 40 minutes to obtain lanthanum carbonate hydrate at pH 3.0. Seed crystals were inoculated. After keeping the temperature at 25 ° C.
  • a 16.4% sodium carbonate aqueous solution (ratio of 0.074 mol to 1 mol of lanthanum oxide) was added dropwise over 10 minutes to adjust the pH to 4.0. After keeping the temperature at 25 ° C. for 40 minutes, the generated crystals were filtered and washed with water (1 part by weight). The filtrate and the washing solution were combined, heated to 50 ° C., and 35% hydrochloric acid (ratio of 0.52 mol to 1 mol of lanthanum oxide) was added. A 16.4% aqueous sodium carbonate solution (ratio of 0.31 mol to 1 mol of lanthanum oxide) was added dropwise at 50 ° C.
  • the obtained crystals were washed with water (24 parts by weight), dried at 40 ° C (bath temperature) and then dried under reduced pressure at 90 ° C to obtain lanthanum carbonate hydrate in a yield of 94%.
  • the amount of elemental impurities in the obtained crystal was measured by inductively coupled plasma mass spectrometry.
  • Example 2 Water (3 parts by weight) was added to lanthanum oxide (1 part by weight), the mixture was heated to 40 ° C., 35% hydrochloric acid (a ratio of 6.3 mol to 1 mol of lanthanum oxide) was added dropwise, and a lanthanum chloride aqueous solution was added. Obtained. During this period, the liquid temperature was 38 to 55 ° C. A 16.4% sodium carbonate aqueous solution (ratio of 0.22 mol to 1 mol of lanthanum oxide) was added dropwise to the obtained lanthanum chloride aqueous solution at 25 ° C. over 30 minutes to obtain lanthanum carbonate hydrate at pH 3.9. Seed crystals were inoculated. After keeping the temperature at 25 ° C.
  • a 16.4% sodium carbonate aqueous solution (ratio of 0.22 mol to 1 mol of lanthanum oxide) was added dropwise over 30 minutes to adjust the pH to 3.7. After keeping the temperature at 25 ° C. for 30 minutes, the generated crystals were filtered and washed with water (1 part by weight). The filtrate and the washing solution were combined, the temperature was raised to 30 ° C., and seed crystals of lanthanum carbonate hydrate were inoculated. A 16.4% aqueous sodium carbonate solution was added dropwise over 4 hours and 40 minutes to adjust the pH to 6.2. After keeping the temperature at 30 ° C. for 17 hours, the precipitated crystals were filtered.
  • the obtained crystals were washed with water (24 parts by weight) and then dried at 40 ° C. (bath temperature) to obtain lanthanum carbonate hydrate with a yield of 89%.
  • the amount of elemental impurities in the obtained crystal was measured by inductively coupled plasma mass spectrometry.
  • Example 3 Water (3 parts by weight) was added to lanthanum oxide (1 part by weight), the mixture was heated to 40 ° C., 35% hydrochloric acid (a ratio of 6.3 mol to 1 mol of lanthanum oxide) was added dropwise, and a lanthanum chloride aqueous solution was added. Obtained. The liquid temperature during this period was 39 to 52 ° C. A 16.4% sodium carbonate aqueous solution (ratio of 0.21 mol to 1 mol of lanthanum oxide) was added dropwise to the obtained lanthanum chloride aqueous solution at 25 ° C. over 40 minutes to adjust the pH to 2.5, and lanthanum carbonate hydrate was prepared. Seed crystals were inoculated.
  • a 16.4% sodium carbonate aqueous solution (ratio of 0.0013 mol to 1 mol of lanthanum oxide) was dropped, and the temperature was kept for 30 minutes. Then, a 16.4% sodium carbonate aqueous solution (ratio of 0.52 mol to 1 mol of lanthanum oxide) was added dropwise at 25 ° C. over 75 minutes to adjust the pH to 3.7. After keeping the temperature at 25 ° C. for 45 minutes, the generated crystals were filtered and washed with water (1 part by weight). The filtrate and the washing solution were combined, the temperature was raised to 50 ° C., and 35% hydrochloric acid (ratio of 0.52 mol to 1 mol of lanthanum oxide) was added.
  • a 16.4% aqueous sodium carbonate solution (ratio of 0.31 mol to 1 mol of lanthanum oxide) was added dropwise at 50 ° C. over 45 minutes to inoculate a seed crystal of lanthanum carbonate hydrate at pH 2.5.
  • a 16.4% sodium carbonate aqueous solution (ratio of 0.038 mol to 1 mol of lanthanum oxide)
  • the mixture was kept warm at 50 ° C. for 40 minutes.
  • a 16.4% sodium carbonate aqueous solution was added dropwise at 50 to 51 ° C. over 4 hours and 10 minutes to adjust the pH to 6.0. After keeping the temperature at 50 ° C for 20 minutes, it was cooled to 30 to 35 ° C.
  • the precipitated crystals were filtered.
  • the obtained crystals were washed with water (24 parts by weight), dried at 40 ° C. (bath temperature) and then dried under reduced pressure at 90 ° C. to obtain lanthanum carbonate hydrate with a yield of 80%.
  • the amount of elemental impurities in the obtained crystal was measured by inductively coupled plasma mass spectrometry.
  • Reference Example Water (3 parts by weight) was added to lanthanum oxide (1 part by weight), and the mixture was heated to 40 ° C. and 35% hydrochloric acid (a ratio of 6.3 mol to 1 mol of lanthanum oxide) was added dropwise to the lanthanum chloride. An aqueous solution was obtained. The liquid temperature during this period was 39 to 52 ° C. 35% Hydrochloric acid (ratio of 0.52 mol to 1 mol of lanthanum oxide) was added to the obtained lanthanum chloride aqueous solution. Then, a 16.4% sodium carbonate aqueous solution (a ratio of 0.47 mol to 1 mol of lanthanum oxide) was added dropwise at 25 ° C. over 40 minutes.
  • Seed crystals of lanthanum carbonate hydrate at pH 2.8 were inoculated. After dropwise addition of a 16.4% aqueous sodium carbonate solution (ratio of 0.0013 mol to 1 mol of lanthanum oxide), the mixture was kept warm at 25 ° C. for 30 minutes. At 25 ° C., a 16.4% sodium carbonate aqueous solution (ratio of 0.074 mol to 1 mol of lanthanum oxide) was added dropwise over 10 minutes. After keeping the temperature at 25 ° C. for 30 minutes, the temperature was raised to 50 ° C., and a 16.4% sodium carbonate aqueous solution was added dropwise at 49 to 50 ° C. over 4 hours and 40 minutes to adjust the pH to 5.7.
  • a 16.4% sodium carbonate aqueous solution ratio of 0.0013 mol to 1 mol of lanthanum oxide
  • Table 1 shows the contents (ppm) of lead (Pb), arsenic (As), and vanadium (V) in the lanthanum carbonate hydrates and the raw material lanthanum oxide obtained in each Example and Reference Example.
  • Example 4 Water (3 parts by weight) was added to lanthanum oxide (1 part by weight), the mixture was heated to 40 ° C., 35% hydrochloric acid (a ratio of 6.3 mol to 1 mol of lanthanum oxide) was added dropwise, and a lanthanum chloride aqueous solution was added. Obtained. The liquid temperature during this period was 40 to 50 ° C. To the obtained lanthanum chloride aqueous solution, a 15.1% ammonium carbonate aqueous solution (ratio of 0.22 mol to 1 mol of lanthanum oxide) was added dropwise at 25 ° C. over 30 minutes. Seed crystals of lanthanum carbonate hydrate were inoculated at pH 3.7 and kept warm for 30 minutes.
  • a 15.1% ammonium carbonate aqueous solution (ratio of 0.52 mol to 1 mol of lanthanum oxide) was added dropwise over 55 minutes to adjust the pH to 3.6. After keeping the temperature at 25 ° C. for 40 minutes, the generated crystals were filtered and washed with water (1 part by weight). The filtrate and the washing solution were combined, the temperature was raised to 30 ° C., and seed crystals of lanthanum carbonate hydrate were inoculated. A 15.1% ammonium carbonate aqueous solution was added dropwise over 4 hours and 30 minutes to adjust the pH to 6.0. After keeping the temperature at 30 ° C. for 1 hour and 10 minutes, the precipitated crystals were filtered.
  • the obtained crystals were washed with water (24 parts by weight) and dried under reduced pressure at 40 ° C (bath temperature) to obtain lanthanum carbonate hydrate with a yield of 81%.
  • the amount of elemental impurities in the obtained crystal was measured by inductively coupled plasma mass spectrometry.
  • Example 5 Water (4 parts by weight) was added to lanthanum oxide (1 part by weight), and the mixture was heated to 40 ° C. and 70% nitric acid (a ratio of 6.3 mol to 1 mol of lanthanum oxide) was added dropwise to the lanthanum nitrate aqueous solution. Obtained. The liquid temperature during this period was 40 to 67 ° C. To the obtained lanthanum nitrate aqueous solution, a 15.1% ammonium carbonate aqueous solution (ratio of 0.22 mol to 1 mol of lanthanum oxide) was added dropwise at 25 ° C. over 30 minutes. Seed crystals of lanthanum carbonate hydrate were inoculated at pH 3.6 and kept warm for 30 minutes.
  • a 15.1% ammonium carbonate aqueous solution (ratio of 0.52 mol to 1 mol of lanthanum oxide) was added dropwise over 25 minutes to adjust the pH to 3.5. After keeping the temperature at 25 ° C. for 30 minutes, the generated crystals were filtered and washed with water (1 part by weight). The filtrate and washings were combined and seeded with lanthanum carbonate hydrate seed crystals at 27 ° C.
  • a 15.1% ammonium carbonate aqueous solution was added dropwise over 3 hours and 45 minutes to adjust the pH to 6.0. After keeping the temperature at 30 ° C. for 16 hours and 40 minutes, the precipitated crystals were filtered.
  • the obtained crystals were washed with water (24 parts by weight) and then dried under reduced pressure at 40 ° C. (bath temperature) to obtain lanthanum carbonate hydrate with a yield of 80%.
  • the amount of elemental impurities in the obtained crystal was measured by inductively coupled plasma mass spectrometry.
  • lanthanum carbonate hydrate used as a therapeutic agent for hyperphosphatemia in a patient with chronic renal failure can be produced in high purity with less elemental impurities.

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Geology (AREA)
  • Inorganic Chemistry (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)

Abstract

L'invention concerne un procédé de génération d'une hydrate de carbonate de lanthane de haute pureté et à faible teneur en impuretés d'élément. Ledit procédé peut comprendre les étapes consistant à : ajouter un sel de carbonate, par exemple du carbonate de sodium, à une solution aqueuse préparée par réaction d'oxyde de lanthane avec un acide capable de générer un sel soluble de lanthane, par exemple de l'acide chlorhydrique, pour ajuster la valeur de pH de la solution aqueuse entre 2,9 et 4,5 afin de générer une matière solide; puis retirer la matière solide pour générer une fraction liquide, puis ajouter un sel de carbonate à la fraction liquide pour ajuster la valeur de pH de la fraction liquide entre 5,5 et 7.
PCT/JP2019/038872 2018-10-26 2019-10-02 Procédé de génération d'hydrate de carbonate de lanthane WO2020085020A1 (fr)

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CN201980067496.5A CN112867695A (zh) 2018-10-26 2019-10-02 水合碳酸镧的制造方法
MX2021004516A MX2021004516A (es) 2018-10-26 2019-10-02 Metodo para produccion de hidrato de carbonato de lantano.
JP2020553034A JP7300461B2 (ja) 2018-10-26 2019-10-02 炭酸ランタン水和物の製造方法

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11503119A (ja) * 1995-03-25 1999-03-23 ジョンソン マッセイ パブリック リミティド カンパニー 選択された炭酸ランタン水和物を含有する医薬組成物
CN102041389A (zh) * 2010-11-05 2011-05-04 内蒙古包钢稀土(集团)高科技股份有限公司 一种循环回用碳酸稀土沉淀废液生产碳酸稀土的方法
CN102432055A (zh) * 2011-09-23 2012-05-02 北京大学 用于治疗高磷血症的碳酸镧纳米颗粒、其制备方法及用途
CN107188215A (zh) * 2017-05-24 2017-09-22 中国北方稀土（集团）高科技股份有限公司 碳酸稀土连续沉淀生产过程中自动调节反应终点的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4112687B2 (ja) * 1998-06-12 2008-07-02 株式会社日本触媒 エーテルカルボン酸塩の製造法
US7576329B2 (en) * 2003-10-17 2009-08-18 General Electric Company Scintillator compositions, and related processes and articles of manufacture
CN102442692B (zh) * 2011-09-23 2014-08-27 北京大学 碳酸镧水合物的制备方法
CN103502511A (zh) * 2011-09-28 2014-01-08 吉坤日矿日石金属株式会社 高纯度镧的制造方法、高纯度镧、包含高纯度镧的溅射靶及以高纯度镧为主要成分的金属栅极膜
CN104973617A (zh) * 2015-07-01 2015-10-14 乐山沃耐稀电子材料有限公司 一种无水氯化镧的制备方法
CN105502470B (zh) 2015-12-31 2017-08-04 瑞科稀土冶金及功能材料国家工程研究中心有限公司 一种低杂质夹带碳酸镧或碳酸镧铈的制备方法
CN106044838B (zh) * 2016-07-28 2017-05-24 乐山沃耐稀电子材料有限公司 一种低硫氢氧化镧生产工艺

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11503119A (ja) * 1995-03-25 1999-03-23 ジョンソン マッセイ パブリック リミティド カンパニー 選択された炭酸ランタン水和物を含有する医薬組成物
CN102041389A (zh) * 2010-11-05 2011-05-04 内蒙古包钢稀土(集团)高科技股份有限公司 一种循环回用碳酸稀土沉淀废液生产碳酸稀土的方法
CN102432055A (zh) * 2011-09-23 2012-05-02 北京大学 用于治疗高磷血症的碳酸镧纳米颗粒、其制备方法及用途
CN107188215A (zh) * 2017-05-24 2017-09-22 中国北方稀土（集团）高科技股份有限公司 碳酸稀土连续沉淀生产过程中自动调节反应终点的方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EWING, K. J. ET AL.: "Preparation of high purity lanthanum compounds for use in fluoride optical fibers", MATERIALS RESEARCH BULLETIN, vol. 24, 1989, pages 163 - 168, XP024079210, DOI: 10.1016/0025-5408(89)90120-7 *

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