WO2013146181A1 - 乳化食品組成物 - Google Patents

乳化食品組成物 Download PDF

Info

Publication number
WO2013146181A1
WO2013146181A1 PCT/JP2013/056422 JP2013056422W WO2013146181A1 WO 2013146181 A1 WO2013146181 A1 WO 2013146181A1 JP 2013056422 W JP2013056422 W JP 2013056422W WO 2013146181 A1 WO2013146181 A1 WO 2013146181A1
Authority
WO
WIPO (PCT)
Prior art keywords
food composition
emulsified food
divalent metal
emulsified
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2013/056422
Other languages
English (en)
French (fr)
Japanese (ja)
Inventor
直之 遠藤
和也 水貝
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Otsuka Pharmaceutical Factory Inc
Original Assignee
Otsuka Pharmaceutical Co Ltd
Otsuka Pharmaceutical Factory Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to KR1020147030101A priority Critical patent/KR102049131B1/ko
Priority to HK15102905.3A priority patent/HK1202380A1/xx
Priority to IN7437DEN2014 priority patent/IN2014DN07437A/en
Priority to US14/385,962 priority patent/US9737088B2/en
Priority to SG11201405400RA priority patent/SG11201405400RA/en
Priority to AU2013238353A priority patent/AU2013238353B2/en
Application filed by Otsuka Pharmaceutical Co Ltd, Otsuka Pharmaceutical Factory Inc filed Critical Otsuka Pharmaceutical Co Ltd
Priority to CN201380016497.XA priority patent/CN104203007A/zh
Priority to JP2014502919A priority patent/JP5590638B2/ja
Publication of WO2013146181A1 publication Critical patent/WO2013146181A1/ja
Priority to PH12014501948A priority patent/PH12014501948B1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L35/00—Foods or foodstuffs not provided for in groups A23L5/00 - A23L33/00; Preparation or treatment thereof
    • A23L35/10—Emulsified foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L21/00—Marmalades, jams, jellies or the like; Products from apiculture; Preparation or treatment thereof
    • A23L21/10—Marmalades; Jams; Jellies; Other similar fruit or vegetable compositions; Simulated fruit products
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/015—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A23L29/231—Pectin; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A23L29/25—Exudates, e.g. gum arabic, gum acacia, gum karaya or tragacanth
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Definitions

  • the present invention relates to an emulsified food composition that has good fluidity and emulsion stability even when subjected to heat sterilization treatment, and can prevent backflow of the gastroesophagus by gelation when entering the stomach.
  • a tube feeding supplemental method in which a liquid food is directly administered into the stomach through a tube.
  • this tube feeding method it is important to suppress gastroesophageal reflux in which the liquid food administered into the stomach flows back toward the esophagus.
  • an emulsified food composition that has good fluidity and emulsion stability even when subjected to heat sterilization treatment, and can prevent backflow of the gastroesophagus by gelation when entering the stomach Development is desired.
  • JP 2004-26844 A International Publication No. 2000/013529 Pamphlet JP 2011-147444 A
  • An object of the present invention is to provide an emulsified food composition that has good fluidity and emulsion stability even when subjected to heat sterilization treatment, and can prevent backflow of the gastroesophagus by gelation when entering the stomach. is there.
  • the present inventor has conducted intensive studies to solve the above problems, and in an emulsified food composition containing lipids, at least selected from the group consisting of gum arabic and gati gum together with a thickener that gels in the acidic region.
  • lipids at least selected from the group consisting of gum arabic and gati gum together with a thickener that gels in the acidic region.
  • a divalent metal salt By blending one type of emulsion stabilizer and a divalent metal salt, it is possible to improve fluidity and emulsion stability even if it is subjected to heat sterilization treatment while having the property of gelation when entering the stomach. It has been found that it can be suitably used as a liquid food for preventing gastroesophageal reflux, especially as a liquid food for dysphagia.
  • the present invention has been completed by further studies based on such knowledge.
  • Item 1 (A) a lipid, (B) a thickener that gels in an acidic region, (C) at least one emulsion stabilizer selected from the group consisting of gum arabic and gati gum, and (D) a divalent metal salt.
  • An emulsified food composition characterized by comprising.
  • Item 2. Item 5. The emulsified food composition according to Item 1, wherein the pH is 5.5 or more and less than 9.
  • Item 3. Item 2. The emulsified food composition according to Item 1, further comprising at least one selected from the group consisting of proteins and carbohydrates.
  • the emulsified food composition according to Item 1 wherein the thickening agent that gels in the acidic region (B) is at least one selected from the group consisting of pectin, alginic acid, a salt of alginic acid, and gellan gum.
  • Item 5. Item 2. The emulsified food composition according to Item 1, wherein the thickening agent that gels in the acidic region (B) is low methoxyl pectin.
  • the emulsified food composition according to Item 1, wherein the (D) divalent metal salt is an insoluble salt that liberates a divalent metal ion in an acidic region.
  • Item 8. (A) 0.1-100 g / L of lipid, (B) 1-70 g / L of a thickener that gels in the acidic region, (C) at least one selected from the group consisting of gum arabic and gati gum Item 5.
  • the emulsified food composition according to Item 1, comprising 0.5 to 70 g / L of an emulsion stabilizer and 0.1 to 10 g / L of (D) a divalent metal salt.
  • Item 9. Item 2.
  • the emulsified food composition according to Item 1 wherein the viscosity at 25 ° C is 2 to 100 mPa ⁇ s.
  • Item 2. The emulsified food composition according to Item 1, which is used for feeding a dysphagic person.
  • Item 11. At least one selected from the group consisting of (A) a lipid, (B) a thickener that gels in an acidic region, (C) gum arabic and gati gum for the production of enteral nutrients for dysphagia And (D) an emulsified food composition containing a divalent metal salt.
  • A a lipid
  • B a thickener that gels in an acidic region
  • C gum arabic and gati gum for the production of enteral nutrients for dysphagia
  • D an emulsified food composition containing a divalent metal salt.
  • a method for feeding a dysphagic person (A) a lipid, (B) a thickener that gels in an acidic region, (C) at least one emulsion stabilizer selected from the group consisting of gum arabic and gati gum, and (D) a divalent metal salt.
  • a nutritional supplementation method comprising a step of tube-administering the emulsified food composition to a person with dysphagia.
  • the emulsified food composition of the present invention has excellent fluidity and emulsification stability and gels when entering the stomach, so that tube administration can be easily performed, and the reflux of the gastroesophagus is prevented. It is also possible.
  • the emulsified food composition of the present invention can maintain excellent fluidity and emulsion stability even after heat sterilization treatment. Therefore, the emulsified food composition of the present invention can be subjected to heat sterilization such as pressure heat sterilization and ultra-high temperature instantaneous sterilization (UHT), and can be distributed at room temperature or stored for a long time. Not only is there a great advantage in terms of quality control.
  • heat sterilization such as pressure heat sterilization and ultra-high temperature instantaneous sterilization (UHT)
  • Test Example 1 the results of photographing the appearance of each emulsified food composition after being left overnight are shown.
  • the emulsified food composition of the present invention may be expressed as a lipid (hereinafter also referred to as “component (A)”), a thickener that gels in an acidic region (hereinafter referred to as “component (B)”). And at least one emulsion stabilizer selected from the group consisting of gum arabic and gati gum (hereinafter also referred to as “component (C)”), and a divalent metal salt (hereinafter referred to as “(D)”). It may be described as “component”).
  • component (A) lipid
  • component (B) a thickener that gels in an acidic region
  • component (C) emulsion stabilizer selected from the group consisting of gum arabic and gati gum
  • (D) divalent metal salt
  • the emulsified composition of the present invention contains a lipid as the component (A).
  • the type of lipid used in the present invention is not particularly limited.
  • rice oil, coconut oil, soybean oil, corn oil, rapeseed oil, palm oil, safflower oil, sunflower oil, soybean oil, olive oil, cottonseed oil Vegetable oils such as peanut oil and cacao butter; animal oils such as fish oil, beef tallow and lard; fatty acids, medium chain fatty acids (about 6 to 12 carbon atoms) triglycerides, docosahexaenoic acid, eicosapentaenoic acid and the like.
  • the fats and oils blended in the emulsified food composition of the present invention may be one kind alone or a combination of two or more kinds.
  • the blending amount of the component (A) in the emulsified food composition of the present invention is appropriately set according to the type of the component (A) to be used, etc., for example, 0.1 to 100 g / L, preferably 5 to 70 g / L, more preferably 10 to 40 g / L.
  • the emulsified composition of the present invention contains a thickener that gels in the acidic region as the component (B).
  • the thickener that gels in the acidic region is not particularly limited as long as it is edible and does not gel in the neutral region and exhibits a property of gelling in the acidic region.
  • Examples of such a thickener include a thickener that gels in a region where the pH is about 5 or less, and specifically includes pectin, alginic acid, a salt of alginic acid, gellan gum, carrageenan, and the like.
  • the pectin is a polysaccharide obtained by acid extraction from plants such as sugar beet, sunflower, orange, grapefruit, lime, lemon and apple.
  • the pectin used in the present invention may be obtained by extraction from the plant or the like, or may be produced using chemical synthesis, enzyme synthesis, microbial fermentation, or the like.
  • the pectin used in the present invention may be either a high methoxyl pectin having an esterification degree of 50% or more, a low methoxyl pectin having an esterification degree of less than 50%, or a mixture thereof. . From the viewpoint of more effectively providing gelling properties when entering the stomach while having excellent fluidity and emulsion stability, low methoxyl pectin is preferably used.
  • the alginic acid and alginic acid salt are polysaccharides obtained by extraction from algae such as brown algae.
  • the alginic acid and alginic acid salt used in the present invention may be obtained by extraction from the algae and the like, and are produced using chemical synthesis, enzymatic synthesis, microbial fermentation, etc. Also good.
  • specific examples of the salt of alginic acid include alkali metal salts such as sodium salt and potassium salt.
  • the gellan gum is a polysaccharide produced by Sphingomonas elodea.
  • the gellan gum used in the present invention may be obtained by fermentation of the microorganism or the like, or may be produced using chemical synthesis, enzyme synthesis, or the like.
  • the carrageenan is a polysaccharide obtained by extraction from algae such as red algae.
  • the carrageenan used in the present invention may be obtained by extraction from the algae or the like, or may be produced using chemical synthesis, enzyme synthesis, or the like.
  • pectin and alginic acid are preferred from the viewpoint of more effectively providing gelling properties when entering the stomach while maintaining fluidity and emulsion stability even after heat sterilization treatment.
  • the blending amount of the component (B) in the emulsified food composition of the present invention is appropriately set according to the type of the component (B) to be used, but is, for example, 1 to 70 g / L, preferably 3 to 50 g / L. L, more preferably 5 to 30 g / L.
  • the emulsified food composition of the present invention contains at least one emulsion stabilizer selected from the group consisting of gum arabic and gati gum as component (C).
  • the gum arabic is dried from a resin of leguminous arabic gum (Acacia senegal) or a plant related to the same genus (for example, Acacia senegal, Acacia abysinica, Acacia glaucophylla, Acacia reficiens, Acacia fistula, Acacia giraffae). It is a thickener obtained by this.
  • the gum arabic used in the present invention may be obtained from the above plant, or may be produced using chemical synthesis, enzymatic synthesis, or the like.
  • the gati gum is a thickener obtained by drying sap extracted from the trunk of a plant such as Anogeissus latifolia.
  • the gati gum used in the present invention may be obtained from the above plant, or may be produced using chemical synthesis, enzymatic synthesis, or the like.
  • one type may be selected from gum arabic and gati gum, or a combination thereof may be used.
  • gati gum is preferably used from the viewpoint of more effectively providing gelling properties when entering the stomach while maintaining fluidity and emulsion stability even after heat sterilization treatment. Can be mentioned.
  • the blending amount of the component (C) in the emulsified food composition of the present invention is appropriately set according to the type of the component (C) to be used and the like, for example, 0.5 to 70 g / L, preferably 0. 5 to 50 g / L.
  • the amount of component (C) in the emulsified food composition of the present invention is usually 20 to 70 g / L, preferably 30 to 60 g / L. More preferred is 40 to 50 g / L.
  • the amount of component (C) in the emulsified food composition of the present invention is usually 0.5 to 20 g / L, preferably 0.5 to 15 g / L, More preferred is 3 to 10 g / L, and particularly preferred is 3 to 7.5 g / L.
  • the emulsified food composition of the present invention contains a divalent metal salt as component (D).
  • component (D) a divalent metal salt
  • the emulsion composition of the present invention has good fluidity and emulsion stability even when subjected to heat sterilization treatment, It becomes possible to have the property of gelling when entering.
  • divalent metal constituting the divalent metal salt examples include magnesium, calcium, barium and the like. Of these, magnesium and calcium are preferable.
  • the divalent metal salt used in the present invention is an insoluble salt that liberates the divalent metal ion in the acidic region. It is preferable.
  • an insoluble salt that liberates a divalent metal ion in the acidic region is insoluble or hardly soluble in the neutral and basic regions, but dissolves and liberates the divalent metal ion in the acidic region.
  • “Insoluble” means that 10,000 g or more of water is required to dissolve 1 g of sample, and “slightly soluble” means 1,000 to 10,000 g to dissolve 1 g of sample. Refers to those that need water.
  • insoluble salt that liberates a divalent metal ion in the acidic region When used as the component (D), it does not promote thickening or gelation during distribution or storage. It becomes possible to promote thickening and gelation of the thickener.
  • specific examples of insoluble salts that liberate divalent metal ions in the acidic region include divalent metal phosphates such as tricalcium phosphate and trimagnesium phosphate; divalent such as calcium oxide and magnesium oxide.
  • Metal oxides Divalent metal carbonates such as calcium carbonate and magnesium carbonate. Among these, a divalent metal phosphate is preferable.
  • divalent metal salts liberate divalent metal ions in the neutral region by applying a gastric coating or forming soluble complex ions in combination with normal phosphates or polymerized phosphates. Without being dilute, divalent metal ions can be liberated at acidic pH, even if they are divalent metal chlorides, divalent metal sulfates, divalent metal salts of organic acids, etc. Good.
  • These components (D) may be used singly or in combination of two or more.
  • components (D) from the viewpoint of more effectively having the property of gelling when entering the stomach while maintaining fluidity and emulsion stability even after heat sterilization treatment, it is preferably divalent.
  • the blending amount of the component (D) in the emulsified food composition of the present invention is appropriately set according to the type of the component (C) to be used and the like, for example, 0.1 to 10 g / L, preferably 0. 5 to 7 g / L, more preferably 1 to 5 g / L.
  • the emulsified food composition of the present invention may contain either protein or carbohydrate, preferably both of them.
  • the protein is not particularly limited in its origin, and examples thereof include plant origin such as soybean, wheat, pea, rice, etc .; animal origin such as egg, seafood, meat, milk, collagen and the like. In addition, these proteins may be reduced in molecular weight by enzymatic degradation or the like.
  • the protein blended in the emulsified food composition of the present invention may be a single type or a combination of two or more types.
  • the blending amount is appropriately set according to the type of protein to be used, etc., for example, 5 to 100 g / L, preferably 10 to 80 g / L. More preferred is 30 to 70 g / L.
  • the type of the carbohydrate is not particularly limited, and examples thereof include monosaccharides such as glucose, galactose, fructose, and xylose; disaccharides such as sucrose, lactose, and maltose; galactooligosaccharide, xylooligosaccharide, and soybean.
  • Examples include oligosaccharides such as oligosaccharides, fructo-oligosaccharides, and dairy oligosaccharides; polysaccharides such as dextrin, dietary fiber, and starch.
  • the saccharide compounded in the emulsified food composition of the present invention may be a single saccharide, or a combination of two or more.
  • the blending amount is appropriately set according to the type of saccharide to be used, etc., for example, 1 to 500 g / L, preferably 10 to 400 g. / L, more preferably 100 to 300 g / L.
  • the emulsified food composition of the present invention is in an emulsified form and contains water.
  • the amount of water in the emulsified food composition of the present invention is not particularly limited, and examples thereof include 500 to 990 g / L, preferably 600 to 950 g / L, and more preferably 700 to 900 g / L.
  • the emulsified food composition of the present invention further contains, if necessary, emulsifiers such as lecithin, sucrose fatty acid ester, glycerin fatty acid ester, sorbitan fatty acid ester, pH adjusters, vitamins, minerals, sweeteners, antioxidants, Additives such as preservatives, seasonings, coloring agents, and fragrances may be included.
  • emulsifiers such as lecithin, sucrose fatty acid ester, glycerin fatty acid ester, sorbitan fatty acid ester, pH adjusters, vitamins, minerals, sweeteners, antioxidants, Additives such as preservatives, seasonings, coloring agents, and fragrances may be included.
  • the emulsified form of the emulsified food composition of the present invention is not particularly limited and may be either an oil-in-water type or a water-in-oil type, preferably an oil-in-water type.
  • the pH of the emulsified food composition of the present invention is usually 5.5 or more and less than 9, preferably 6.0 from the viewpoint of maintaining good fluidity without being gelled or thickened during distribution and storage. To 8.0.
  • the viscosity of the emulsified food composition of the present invention is usually 2 to 100 mPa ⁇ s, preferably 3 to 70 mPa ⁇ s, and more preferably 5 to 50 mPa ⁇ s.
  • Administration with a sputum tube or a nasal tube can be performed easily.
  • the viscosity is a value measured at 25 ° C. using a B-type viscometer, using an L adapter, and setting the rotation speed to 12 rpm.
  • the energy density of the emulsified food composition of the present invention is not particularly limited, and is appropriately set according to the purpose of use.
  • the energy density is 0.1 to 7 kcal / g, preferably 0.3 to 5 kcal / g. More preferred is 0.5 to 3 kcal / g.
  • the manufacturing method of the emulsified food composition of this invention does not restrict
  • the emulsified composition of the present invention is obtained by adding and mixing a predetermined amount of components (A) to (D) and other components to be blended as necessary to water, followed by emulsification with a homogenizer. Can be manufactured.
  • the order of addition of each compounding component is not particularly limited, but when the component (B) is added, the liquid mixture to which the component (B) is added is a gel by the component (B). It is desirable to adjust to a pH range where no conversion occurs.
  • the emulsified food composition of the present invention is subjected to a heat sterilization treatment before or after filling into a container such as an aluminum pouch or a soft bag.
  • a heat sterilization treatment is not particularly limited, and examples include 110 to 150 ° C., preferably 120 to 145 ° C.
  • Specific examples of the heat sterilization treatment include pressure heat sterilization, ultra high temperature instantaneous sterilization (UHT), high temperature short time sterilization (HTST) and the like. Even if such heat sterilization treatment is performed, the emulsion composition of the present invention can suppress thickening and gelation, and can stably maintain fluidity and an emulsified state without causing aggregates and layer separation. Can do.
  • the emulsified food composition of the present invention can be used as a dietary supplement for healthy individuals, but has a property of gelling when entering the stomach while having adequate fluidity until entering the stomach. Therefore, it is preferably used as a food used for a person who is required to prevent gastroesophageal reflux (that is, a food for preventing gastroesophageal reflux), particularly as an enteral nutrient for dysphagia. Furthermore, the emulsified food composition of the present invention is useful as a diarrhea-preventing food because it can gel when entering the stomach to adjust the passage time of food in the digestive tract and prevent diarrhea.
  • the intake or administration form of the emulsified food composition of the present invention is not particularly limited.
  • oral intake can be mentioned, and when used for patients with dysphagia, gastrostomy tubes (catheters) or nasal tubes (catheters) can be used. Tube administration.
  • the ingestion or dosage of the emulsified food composition of the present invention is appropriately set according to the energy density, symptoms or sex of the person who is ingested or administered, sex, age, etc.
  • the intake or dose of the emulsified food composition is about 50 to 1000 g, preferably about 150 to 600 g, and about 1 to 5 times a day, preferably about 1 to 3 times a day.
  • Test Example 1 Evaluation of emulsion stability An emulsified food composition (OW type) having the composition shown in Table 1 was prepared. In addition, about the kind and compounding quantity of the used emulsion stabilizer, it is as showing in Table 2. Specifically, after adding each component except low methoxyl pectin to water and mixing with a mixer, pH adjustment (pH 7), low methoxyl pectin is added, and a high pressure homogenizer (used by RANIE 8.30H minilab APV) Homogenization (50MP, 2 passes). The homogenized emulsified food composition was filled in 100 mL of a pouch and then subjected to heat sterilization (121 ° C., 10 minutes). After leaving each emulsified food composition at 25 ° C. overnight after heat sterilization, the presence or absence of oil layer separation was visually confirmed to evaluate the emulsion stability. The evaluation of emulsion stability was performed according to the following criteria.
  • Table 3 shows the obtained results. Moreover, the result of having image
  • Test Example 2 Evaluation of gelation characteristics by mixing with artificial gastric juice Emulsified food compositions (OW type) (Examples 3 and 4) having the composition shown in Table 4 were prepared. Specifically, after adding each component except low methoxyl pectin to water and mixing with a mixer, pH adjustment (pH 7), low methoxyl pectin is added, and a high pressure homogenizer (used by RANIE 8.30H minilab APV) Homogenization (50MP, 2 passes). The homogenized emulsified food composition was filled in 100 mL of a pouch and then subjected to heat sterilization (121 ° C., 10 minutes).
  • OW type artificial gastric juice Emulsified food compositions
  • the emulsified food composition after heat sterilization was taken out from the pouch, and the viscosity at 25 ° C. was measured with a B-type viscometer (RB80L type Toki Sangyo Co., Ltd.) using an L adapter at a rotation speed of 12 rpm.
  • Table 5 shows the results of measuring the viscosity before and after mixing with artificial gastric juice. From these results, it was confirmed that the emulsified food compositions of Examples 3 and 4 had good fluidity until contacted with gastric juice, but increased in viscosity and gelled when contacted with gastric juice. From this result, it was confirmed that when the emulsified food composition of the present invention was administered into the stomach, it gelled to prevent gastroesophageal reflux.
  • Test Example 3 Evaluation of influence of blending amount of gum arabic on emulsification stability
  • the blending amount of gum arabic was changed to obtain an emulsified food composition (OW type) (Example 5-9) having the composition shown in Table 6 Prepared. Specifically, after adding each component except low methoxyl pectin to water and mixing with a mixer, pH adjustment (pH 7), low methoxyl pectin is added, and a high pressure homogenizer (used by RANIE 8.30H minilab APV) Homogenization (50MP, 2 passes). The homogenized emulsified food composition was filled in 100 mL of a pouch and then subjected to heat sterilization (121 ° C., 10 minutes).
  • the emulsified food composition after heat sterilization was taken out from the pouch, and the viscosity at 25 ° C. was measured with a B-type viscometer (RB80L type Toki Sangyo Co., Ltd.) using an L adapter at a rotation speed of 12 rpm. .
  • a B-type viscometer (RB80L type Toki Sangyo Co., Ltd.) using an L adapter at a rotation speed of 12 rpm.
  • the number of rotations was appropriately reduced for measurement.
  • Table 7 shows the obtained results. From this result, the emulsified food composition (Example 5-9) having a gum arabic blending amount of 20 to 70 g / L has excellent emulsification stability and good fluidity before mixing with artificial gastric juice. After mixing with gastric juice, gelation was confirmed to the extent that reflux of the gastroesophagus could be prevented.
  • Test Example 4 Evaluation of the effect of the amount of gati gum on the emulsion stability
  • the emulsified food composition (OW type) (Examples 10-16) having the composition shown in Table 8 was prepared by changing the amount of gati gum. . Specifically, after adding each component except low methoxyl pectin to water and mixing with a mixer, pH adjustment (pH 7), low methoxyl pectin is added, and a high pressure homogenizer (used by RANIE 8.30H minilab APV) Homogenization (50MP, 2 passes). The homogenized emulsified food composition was filled in 100 mL of a pouch and then subjected to heat sterilization (121 ° C., 10 minutes).
  • the emulsified food composition after heat sterilization was taken out from the pouch, and the viscosity at 25 ° C. was measured with a B-type viscometer (RB80L type Toki Sangyo Co., Ltd.) using an L adapter at a rotation speed of 12 rpm. .
  • a B-type viscometer (RB80L type Toki Sangyo Co., Ltd.) using an L adapter at a rotation speed of 12 rpm.
  • the number of rotations was appropriately reduced for measurement.
  • Table 9 shows the obtained results. From this result, the emulsified food composition having a gati gum content of 0.5 to 20 g / L, particularly 3 to 10 g / L, has excellent emulsion stability and good fluidity before mixing with artificial gastric juice, After mixing with artificial gastric juice, gelation was confirmed to the extent that gastroesophageal reflux could be prevented.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pediatric Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Grain Derivatives (AREA)
  • General Preparation And Processing Of Foods (AREA)
PCT/JP2013/056422 2012-03-30 2013-03-08 乳化食品組成物 Ceased WO2013146181A1 (ja)

Priority Applications (9)

Application Number Priority Date Filing Date Title
HK15102905.3A HK1202380A1 (en) 2012-03-30 2013-03-08 Emulsified food product composition
IN7437DEN2014 IN2014DN07437A (OSRAM) 2012-03-30 2013-03-08
US14/385,962 US9737088B2 (en) 2012-03-30 2013-03-08 Emulsified food product composition
SG11201405400RA SG11201405400RA (en) 2012-03-30 2013-03-08 Emulsified food product composition
AU2013238353A AU2013238353B2 (en) 2012-03-30 2013-03-08 Emulsified food product composition
KR1020147030101A KR102049131B1 (ko) 2012-03-30 2013-03-08 유화 식품 조성물
CN201380016497.XA CN104203007A (zh) 2012-03-30 2013-03-08 乳化食品组合物
JP2014502919A JP5590638B2 (ja) 2012-03-30 2013-03-08 乳化食品組成物
PH12014501948A PH12014501948B1 (en) 2012-03-30 2014-08-29 Emulsified food product composition

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012079923 2012-03-30
JP2012-079923 2012-03-30

Publications (1)

Publication Number Publication Date
WO2013146181A1 true WO2013146181A1 (ja) 2013-10-03

Family

ID=49259449

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2013/056422 Ceased WO2013146181A1 (ja) 2012-03-30 2013-03-08 乳化食品組成物

Country Status (12)

Country Link
US (1) US9737088B2 (OSRAM)
JP (2) JP5590638B2 (OSRAM)
KR (1) KR102049131B1 (OSRAM)
CN (2) CN110089736A (OSRAM)
AU (1) AU2013238353B2 (OSRAM)
HK (1) HK1202380A1 (OSRAM)
IN (1) IN2014DN07437A (OSRAM)
MY (1) MY167250A (OSRAM)
PH (1) PH12014501948B1 (OSRAM)
SG (2) SG11201405400RA (OSRAM)
TW (1) TWI584741B (OSRAM)
WO (1) WO2013146181A1 (OSRAM)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015089357A (ja) * 2013-11-06 2015-05-11 ユニテックフーズ株式会社 新規なゲル化剤
JP2015146789A (ja) * 2014-02-07 2015-08-20 三栄源エフ・エフ・アイ株式会社 濃厚流動食
WO2015159990A1 (ja) * 2014-04-17 2015-10-22 三栄源エフ・エフ・アイ株式会社 濃厚流動食
JP2015188364A (ja) * 2014-03-28 2015-11-02 味の素株式会社 栄養組成物
JP2017051133A (ja) * 2015-09-09 2017-03-16 森永製菓株式会社 タンパク質を含んだジェランガムゲル及びその製造方法
JP2018008915A (ja) * 2016-07-15 2018-01-18 学校法人 埼玉医科大学 増粘剤、組成物キット及び組成物を増粘させる方法
WO2018181998A1 (ja) * 2017-03-31 2018-10-04 三栄源エフ・エフ・アイ株式会社 乳化組成物
JP2021122217A (ja) * 2020-02-04 2021-08-30 三栄源エフ・エフ・アイ株式会社 粉末成分を含有する乳化組成物
US11136417B2 (en) 2016-09-30 2021-10-05 San-Ei Gen F.F.I., Inc. Low molecular gum ghatti
WO2021261545A1 (ja) 2020-06-24 2021-12-30 三栄源エフ・エフ・アイ株式会社 流動食
WO2022254950A1 (ja) * 2021-05-31 2022-12-08 ニュートリー株式会社 栄養組成物

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017284391B2 (en) * 2016-06-17 2022-11-17 Otsuka Pharmaceutical Factory, Inc. Diarrhea-preventing nutritional composition
CA3085172A1 (en) * 2017-12-29 2019-07-04 Kraft Foods Group Brands Llc Improved oxidative stability of oil-in-water emulsions using natural stabilizers
JP7359755B2 (ja) * 2018-04-23 2023-10-11 三栄源エフ・エフ・アイ株式会社 乳化組成物
WO2020080009A1 (ja) * 2018-10-18 2020-04-23 奥野製薬工業株式会社 アルミニウム合金の陽極酸化皮膜用封孔処理液
JP2020127387A (ja) * 2019-02-08 2020-08-27 森永乳業株式会社 栄養組成物
WO2020220164A1 (zh) * 2019-04-28 2020-11-05 健康元药业集团股份有限公司 食品组合物及其制备方法和应用、营养食品
CN110074388A (zh) * 2019-04-28 2019-08-02 健康元药业集团股份有限公司 食品组合物及其制备方法和应用、营养食品
CN110353271B (zh) * 2019-06-13 2022-07-22 陕西科技大学 一种抑制食道反流的特殊医学食品增稠组件及其制备方法
WO2021234683A2 (pt) * 2020-05-18 2021-11-25 Duas Rodas Industrial Ltda Turvador para pó para bebidas instantâneas
CN118805891B (zh) * 2024-08-02 2025-02-28 中科爱伽(天津)医用食品有限公司 一种抑制脂肪吸收、控制体重的组合物及其制备方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998042210A1 (en) * 1997-03-24 1998-10-01 Maruo Calcium Company Limited Food additive slurry composition and powder composition and food compositions containing these
WO2005026213A1 (ja) * 2003-09-10 2005-03-24 San-Ei Gen F.F.I., Inc. 改質アラビアガムの製造方法
JP2006522202A (ja) * 2003-04-07 2006-09-28 フィリップス ハイドロコロイド リサーチ リミテッド 改質アラビアガム
JP2008301723A (ja) * 2007-06-05 2008-12-18 Nof Corp 乳化状総合栄養食
JP2011147444A (ja) * 2009-12-25 2011-08-04 Kaneka Corp 乳化食品組成物
WO2012081725A1 (ja) * 2010-12-17 2012-06-21 株式会社カネカ 乳化食品組成物

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE755303A (fr) * 1969-09-05 1971-02-26 Nestle Sa Procede de fabrication d'une composition en poudre pour la preparation de boissons
US5855936A (en) * 1997-03-21 1999-01-05 Nestec S.A. Food fortification
KR100491425B1 (ko) 1997-03-24 2005-05-24 마루오 칼슘 가부시키가이샤 식품첨가제 슬러리 조성물 및 파우더 조성물 및 이들을 함유하는 식품조성물, 그리고 식품첨가제 슬러리 조성물의 제조방법
ATE308898T1 (de) 1998-09-09 2005-11-15 Q P Corp Brechreizunterdrueckende nahrungsmittel
US6365218B1 (en) * 2000-02-04 2002-04-02 Abbott Laboratories Pediatric formula and methods for providing nutrition and improving tolerance
US20030104033A1 (en) * 2001-07-13 2003-06-05 Lai Chon-Si Enteral formulations
ATE354292T1 (de) * 2001-09-19 2007-03-15 Maruo Calcium Pastöse und pulverförmige nahrungsmittelzusatzstoffzusammensetzung sowie diese enthaltende nahrungsmittelzusammensetzung
WO2003035112A1 (fr) 2001-10-22 2003-05-01 Jiro Kanie Nutriant enteral et procede de production de celui-ci
JP4396815B2 (ja) 2001-10-22 2010-01-13 治郎 蟹江 経腸栄養剤およびその製造方法
AU2002336080A1 (en) * 2002-08-03 2004-03-11 Dragoco Gerberding And Co. Ag Spray-dried soluble instant powder and instant powder beverage for producing beverages and corresponding production method
RU2354145C2 (ru) * 2003-09-03 2009-05-10 Юнилевер Н.В. Пищевые композиции, усиливающие чувство сытости
CN101528057A (zh) * 2006-08-24 2009-09-09 荷兰联合利华有限公司 液体饱腹感增强组合物
PL2230940T3 (pl) * 2007-12-05 2015-01-30 Nutricia Nv Wysokoenergetyczna płynna dojelitowa kompozycja odżywcza
CN102014671A (zh) * 2008-04-30 2011-04-13 雀巢产品技术援助有限公司 引起饱足感的食物组合物
CN102056497B (zh) * 2008-06-03 2016-03-02 帝斯曼知识产权资产管理有限公司 含有茄替胶的脂溶性活性成分的组合物
MX2011005078A (es) * 2008-11-18 2012-01-27 One S R L Metodos y composiciones para el control del peso y para mejorar el control glucémico.
JP5192356B2 (ja) * 2008-12-01 2013-05-08 三栄源エフ・エフ・アイ株式会社 飲料用乳化組成物
JP5329280B2 (ja) 2009-03-31 2013-10-30 テルモ株式会社 酸性タイプ液状経腸栄養剤
JP5910084B2 (ja) * 2009-12-18 2016-04-27 株式会社カネカ 液状食品組成物

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998042210A1 (en) * 1997-03-24 1998-10-01 Maruo Calcium Company Limited Food additive slurry composition and powder composition and food compositions containing these
JP2006522202A (ja) * 2003-04-07 2006-09-28 フィリップス ハイドロコロイド リサーチ リミテッド 改質アラビアガム
WO2005026213A1 (ja) * 2003-09-10 2005-03-24 San-Ei Gen F.F.I., Inc. 改質アラビアガムの製造方法
JP2008301723A (ja) * 2007-06-05 2008-12-18 Nof Corp 乳化状総合栄養食
JP2011147444A (ja) * 2009-12-25 2011-08-04 Kaneka Corp 乳化食品組成物
WO2012081725A1 (ja) * 2010-12-17 2012-06-21 株式会社カネカ 乳化食品組成物

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015089357A (ja) * 2013-11-06 2015-05-11 ユニテックフーズ株式会社 新規なゲル化剤
JP2015146789A (ja) * 2014-02-07 2015-08-20 三栄源エフ・エフ・アイ株式会社 濃厚流動食
JP2015188364A (ja) * 2014-03-28 2015-11-02 味の素株式会社 栄養組成物
WO2015159990A1 (ja) * 2014-04-17 2015-10-22 三栄源エフ・エフ・アイ株式会社 濃厚流動食
JPWO2015159990A1 (ja) * 2014-04-17 2017-04-13 三栄源エフ・エフ・アイ株式会社 濃厚流動食
EP3132693A4 (en) * 2014-04-17 2018-01-03 San-Ei Gen F.F.I., INC. Concentrated liquid food
US10980268B2 (en) 2014-04-17 2021-04-20 San-Ei Gen F.F.I., Inc. Concentrated liquid food
JP2017051133A (ja) * 2015-09-09 2017-03-16 森永製菓株式会社 タンパク質を含んだジェランガムゲル及びその製造方法
JP2018008915A (ja) * 2016-07-15 2018-01-18 学校法人 埼玉医科大学 増粘剤、組成物キット及び組成物を増粘させる方法
US11136417B2 (en) 2016-09-30 2021-10-05 San-Ei Gen F.F.I., Inc. Low molecular gum ghatti
JPWO2018181998A1 (ja) * 2017-03-31 2020-03-12 三栄源エフ・エフ・アイ株式会社 乳化組成物
CN110709160A (zh) * 2017-03-31 2020-01-17 三荣源有限公司 乳液组合物
WO2018181998A1 (ja) * 2017-03-31 2018-10-04 三栄源エフ・エフ・アイ株式会社 乳化組成物
JP7077301B2 (ja) 2017-03-31 2022-05-30 三栄源エフ・エフ・アイ株式会社 乳化組成物
US11647775B2 (en) 2017-03-31 2023-05-16 San-Ei Gen F.F.I., Inc. Emulsion composition
JP2021122217A (ja) * 2020-02-04 2021-08-30 三栄源エフ・エフ・アイ株式会社 粉末成分を含有する乳化組成物
WO2021261545A1 (ja) 2020-06-24 2021-12-30 三栄源エフ・エフ・アイ株式会社 流動食
JPWO2021261545A1 (OSRAM) * 2020-06-24 2021-12-30
EP4173493A4 (en) * 2020-06-24 2024-06-26 San-Ei Gen F.F.I., INC. LIQUID FOOD
WO2022254950A1 (ja) * 2021-05-31 2022-12-08 ニュートリー株式会社 栄養組成物
CN117279522A (zh) * 2021-05-31 2023-12-22 营养株式会社 营养组合物
KR20240016254A (ko) 2021-05-31 2024-02-06 뉴트리 가부시키가이샤 영양 조성물

Also Published As

Publication number Publication date
SG10201602347SA (en) 2016-05-30
US9737088B2 (en) 2017-08-22
AU2013238353B2 (en) 2016-11-24
JP2014223081A (ja) 2014-12-04
JP5940118B2 (ja) 2016-06-29
JP5590638B2 (ja) 2014-09-17
HK1202380A1 (en) 2015-10-02
TW201343082A (zh) 2013-11-01
US20150045453A1 (en) 2015-02-12
PH12014501948A1 (en) 2014-11-24
CN104203007A (zh) 2014-12-10
JPWO2013146181A1 (ja) 2015-12-10
KR20140148454A (ko) 2014-12-31
IN2014DN07437A (OSRAM) 2015-04-24
PH12014501948B1 (en) 2014-11-24
TWI584741B (zh) 2017-06-01
CN110089736A (zh) 2019-08-06
AU2013238353A1 (en) 2014-09-25
SG11201405400RA (en) 2014-11-27
KR102049131B1 (ko) 2019-11-26
MY167250A (en) 2018-08-14

Similar Documents

Publication Publication Date Title
JP5590638B2 (ja) 乳化食品組成物
JP5632112B2 (ja) 半固形化栄養剤
JP2011147444A (ja) 乳化食品組成物
JP6277957B2 (ja) 栄養組成物
JP2009274964A (ja) 経管投与用ゲル状酸性濃厚流動食又は栄養剤
JP5925289B2 (ja) 胃瘻用半固形化栄養剤
JP5902815B2 (ja) 酸性液状栄養剤
JP6289377B2 (ja) 濃厚流動食
JPWO2013132670A1 (ja) 半固形化栄養剤
JP5652980B2 (ja) 胃瘻用半固形化栄養剤
CN115697083A (zh) 流食
HK40007833A (en) Emulsified food product composition
JP5632113B2 (ja) 胃瘻用半固形栄養剤
JP2025027869A (ja) たんぱく質胃排出調整用組成物、流動性栄養組成物、及び組成物
JP2014172832A (ja) 半固形化流動食又は栄養剤

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 13768606

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2014502919

Country of ref document: JP

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 14385962

Country of ref document: US

ENP Entry into the national phase

Ref document number: 2013238353

Country of ref document: AU

Date of ref document: 20130308

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 20147030101

Country of ref document: KR

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: IDP00201406595

Country of ref document: ID

122 Ep: pct application non-entry in european phase

Ref document number: 13768606

Country of ref document: EP

Kind code of ref document: A1