WO2010018926A3 - N-치환 말레이미드류의 제조방법 - Google Patents

N-치환 말레이미드류의 제조방법 Download PDF

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Publication number
WO2010018926A3
WO2010018926A3 PCT/KR2009/003405 KR2009003405W WO2010018926A3 WO 2010018926 A3 WO2010018926 A3 WO 2010018926A3 KR 2009003405 W KR2009003405 W KR 2009003405W WO 2010018926 A3 WO2010018926 A3 WO 2010018926A3
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WIPO (PCT)
Prior art keywords
substituted
preparing
substituted maleimides
exclusion
organic solvent
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PCT/KR2009/003405
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English (en)
French (fr)
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WO2010018926A2 (ko
Inventor
김진억
김승일
곽한진
Original Assignee
금호석유화학 주식회사
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Application filed by 금호석유화학 주식회사 filed Critical 금호석유화학 주식회사
Priority to EP09806788.7A priority Critical patent/EP2311804B1/en
Priority to US12/999,420 priority patent/US8283477B2/en
Priority to JP2011522893A priority patent/JP5449357B2/ja
Priority to CN200980125225.7A priority patent/CN102317260B/zh
Publication of WO2010018926A2 publication Critical patent/WO2010018926A2/ko
Publication of WO2010018926A3 publication Critical patent/WO2010018926A3/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
    • C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
    • C07D207/448—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
    • C07D207/452—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide with hydrocarbon radicals, substituted by hetero atoms, directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
    • C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
    • C07D207/448—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide

Abstract

본 발명은 N-치환 말레이미드류의 제조방법에 관한 것으로서, 더욱 상세하게는 기존 N-치환 말레인 아미드산을 제조 후 N-치환 말레이미드류를 제조하는 방법과 달리, N-치환 말레인 아미드산을 별도로 제조하지 않고 반응기에 유기용제, 산 촉매, 탈수 조촉매와 안정화제를 투입한 후, 1차 아민을 투입하여 아민염화하고, 무수말레산을 투입하여 탈수 폐환 반응시키며 생성되는 물을 유기용제와 함께 공비 증류하여 효과적으로 말레이미드 중합체 형성을 억제함으로써 고순도와 고수율의 N-치환 말레이미드류를 제조하는 방법에 관한 것이다. 특히, 본 발명은 공정이 단순화되면서 수율은 높고, 부반응을 최소화하면서 고가의 원료 투입과 까다로운 반응액 처리를 배제하고, 원료와 무수 말레산의 투입시간을 현저히 단축시키는 장점이 있다.
PCT/KR2009/003405 2008-08-11 2009-06-24 N-치환 말레이미드류의 제조방법 WO2010018926A2 (ko)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP09806788.7A EP2311804B1 (en) 2008-08-11 2009-06-24 Method for preparing n-substituted maleimides
US12/999,420 US8283477B2 (en) 2008-08-11 2009-06-24 Method for preparing N-substituted maleimides
JP2011522893A JP5449357B2 (ja) 2008-08-11 2009-06-24 Ｎ−置換マレイミド類の製造方法
CN200980125225.7A CN102317260B (zh) 2008-08-11 2009-06-24 制备n-取代的马来酰亚胺的方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020080078595A KR101068998B1 (ko) 2008-08-11 2008-08-11 Ｎ－치환 말레이미드류의 제조방법
KR10-2008-0078595 2008-08-11

Publications (2)

Publication Number Publication Date
WO2010018926A2 WO2010018926A2 (ko) 2010-02-18
WO2010018926A3 true WO2010018926A3 (ko) 2010-04-08

Family

ID=41669425

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/003405 WO2010018926A2 (ko) 2008-08-11 2009-06-24 N-치환 말레이미드류의 제조방법

Country Status (6)

Country Link
US (1) US8283477B2 (ko)
EP (1) EP2311804B1 (ko)
JP (1) JP5449357B2 (ko)
KR (1) KR101068998B1 (ko)
CN (1) CN102317260B (ko)
WO (1) WO2010018926A2 (ko)

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KR101297785B1 (ko) * 2011-11-18 2013-08-19 문부현 엔-사이클로헥실말레이미드의 제조방법
CN102399180A (zh) * 2011-12-02 2012-04-04 武汉工程大学 酸性离子液体催化合成n-苯基马来酰亚胺的方法
CN102658111B (zh) * 2012-04-01 2013-11-13 东华大学 层层自组装法制备氧化锌/硅藻土纳米复合材料的方法
CN102850253B (zh) * 2012-08-15 2015-03-25 华烁科技股份有限公司 N-苯基马来酰亚胺的精制及成型方法
CN102909074B (zh) * 2012-10-24 2014-04-16 武汉新概念化工有限公司 固载型无毒催化剂及其合成n-苯基马来酰亚胺和n-苯基取代马来酰亚胺中的方法
CN103289472B (zh) * 2013-06-09 2014-09-10 嘉合实业(苏州)有限公司 一种水性油墨分散剂及其制备方法
CN104558095A (zh) * 2015-01-06 2015-04-29 上海华谊（集团）公司 N-取代马来海松酸酰亚胺的制备方法
KR102146094B1 (ko) * 2016-08-24 2020-08-19 주식회사 엘지화학 N-치환 말레이미드 제조용 탈수 반응 촉매, 이의 제조 방법, 및 n-치환 말레이미드의 제조 방법
KR102175831B1 (ko) * 2016-12-28 2020-11-06 주식회사 엘지화학 고체산 촉매를 이용한 n-치환 말레이미드 제조방법
JP6273389B1 (ja) * 2017-02-03 2018-01-31 ケイ・アイ化成株式会社 Ｎ−脂肪族置換マレイミド化合物の製造方法
JP6336192B1 (ja) * 2017-11-22 2018-06-06 ケイ・アイ化成株式会社 脂肪族マレイミドの製造方法
KR102266842B1 (ko) * 2017-12-21 2021-06-21 주식회사 엘지화학 N-치환 말레이미드 제조용 촉매 제조방법
KR102111638B1 (ko) * 2017-12-26 2020-05-15 주식회사 엘지화학 N-치환 말레이미드 정제방법
CN108659219B (zh) * 2018-06-08 2021-02-09 扬州大学 一种聚苯胺的制备方法
CN108623508A (zh) * 2018-07-05 2018-10-09 四川之江高新材料股份有限公司 N-苯基马来酰亚胺的提纯方法
CN109867784B (zh) * 2019-01-11 2021-07-20 宁波浙铁江宁化工有限公司 一种表面接枝磺酸基蒙脱土催化合成聚天冬氨酸的方法
CN115197116A (zh) * 2021-04-12 2022-10-18 中国石油化工股份有限公司 一种n-苯基马来酰亚胺的制备方法

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Publication number Priority date Publication date Assignee Title
EP0257831A1 (en) * 1986-07-31 1988-03-02 Nippon Shokubai Co., Ltd. Method for production of maleimides
EP0334497A2 (en) * 1988-03-25 1989-09-27 Nippon Shokubai Co., Ltd. Method for production of maleimides
JPH05213869A (ja) * 1992-02-03 1993-08-24 Nippon Shokubai Co Ltd マレイミド類の製造方法

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EP0257831A1 (en) * 1986-07-31 1988-03-02 Nippon Shokubai Co., Ltd. Method for production of maleimides
EP0334497A2 (en) * 1988-03-25 1989-09-27 Nippon Shokubai Co., Ltd. Method for production of maleimides
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Also Published As

Publication number Publication date
CN102317260A (zh) 2012-01-11
US20110124882A1 (en) 2011-05-26
EP2311804A4 (en) 2012-01-25
KR20100019855A (ko) 2010-02-19
JP2011530582A (ja) 2011-12-22
CN102317260B (zh) 2014-03-12
US8283477B2 (en) 2012-10-09
EP2311804B1 (en) 2016-03-09
WO2010018926A2 (ko) 2010-02-18
JP5449357B2 (ja) 2014-03-19
KR101068998B1 (ko) 2011-09-30
EP2311804A2 (en) 2011-04-20

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