WO2009128661A3 - 신규 벤조옥사진 벤즈이미다졸 유도체, 이를 포함하는 약학 조성물 및 이의 용도 - Google Patents

신규 벤조옥사진 벤즈이미다졸 유도체, 이를 포함하는 약학 조성물 및 이의 용도 Download PDF

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Publication number
WO2009128661A3
WO2009128661A3 PCT/KR2009/001977 KR2009001977W WO2009128661A3 WO 2009128661 A3 WO2009128661 A3 WO 2009128661A3 KR 2009001977 W KR2009001977 W KR 2009001977W WO 2009128661 A3 WO2009128661 A3 WO 2009128661A3
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WO
WIPO (PCT)
Prior art keywords
benzimidazole derivative
pharmaceutical composition
same
benzoxazine benzimidazole
novel benzoxazine
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PCT/KR2009/001977
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English (en)
French (fr)
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WO2009128661A2 (ko
Inventor
김지덕
윤홍철
조성희
김인우
조민재
이인영
현해정
박현진
박은경
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주식회사 대웅제약
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Priority to AU2009236824A priority Critical patent/AU2009236824B2/en
Priority to EP09733372.8A priority patent/EP2264031B1/en
Priority to US12/934,638 priority patent/US8362012B2/en
Priority to CA2719515A priority patent/CA2719515C/en
Priority to ES09733372.8T priority patent/ES2539290T3/es
Priority to JP2011504927A priority patent/JP5372138B2/ja
Priority to CN200980112215.XA priority patent/CN101983197B/zh
Priority to NZ587771A priority patent/NZ587771A/en
Publication of WO2009128661A2 publication Critical patent/WO2009128661A2/ko
Publication of WO2009128661A3 publication Critical patent/WO2009128661A3/ko

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    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

본 발명은 바닐로이드 수용체-1(Vanilloid Receptor-1)에 대한 길항제로서 신규한 벤조옥사진 벤즈이미다졸 유도체, 이를 포함하는 약학 조성물 및이의 용도에 관한 것으로, 본 발명에 따른 벤조옥사진 벤즈이미다졸 유도체는 바닐로이드 수용체 길항활성 관련 질환의 예방 또는 치료에 유용하게 사용될 수 있다.
PCT/KR2009/001977 2008-04-18 2009-04-16 신규 벤조옥사진 벤즈이미다졸 유도체, 이를 포함하는 약학 조성물 및 이의 용도 WO2009128661A2 (ko)

Priority Applications (8)

Application Number Priority Date Filing Date Title
AU2009236824A AU2009236824B2 (en) 2008-04-18 2009-04-16 A novel benzoxazine benzimidazole derivative, a pharmaceutical composition comprising the same, and a use thereof
EP09733372.8A EP2264031B1 (en) 2008-04-18 2009-04-16 A novel benzoxazine benzimidazole derivative, a pharmaceutical composition comprising the same, and a use thereof
US12/934,638 US8362012B2 (en) 2008-04-18 2009-04-16 Benzoxazine benzimidazole derivative, a pharmaceutical composition comprising the same, and a use thereof
CA2719515A CA2719515C (en) 2008-04-18 2009-04-16 A novel benzoxazine benzimidazole derivative, a pharmaceutical composition comprising the same, and a use thereof
ES09733372.8T ES2539290T3 (es) 2008-04-18 2009-04-16 Un derivado novedoso de benzoxazina bencimidazol, una composición farmacéutica que comprende el mismo y su uso
JP2011504927A JP5372138B2 (ja) 2008-04-18 2009-04-16 新規ベンゾオキサジンベンズイミダゾール誘導体、これを含む薬学組成物およびこの用途
CN200980112215.XA CN101983197B (zh) 2008-04-18 2009-04-16 新型苯并噁嗪苯并咪唑衍生物、含有该衍生物的药物组合物及其用途
NZ587771A NZ587771A (en) 2008-04-18 2009-04-16 Novel benzoxazine benzimidazole derivatives, pharmaceutical composition comprising same, and a use thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20080036301 2008-04-18
KR10-2008-0036301 2008-04-18

Publications (2)

Publication Number Publication Date
WO2009128661A2 WO2009128661A2 (ko) 2009-10-22
WO2009128661A3 true WO2009128661A3 (ko) 2010-01-21

Family

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Family Applications (1)

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PCT/KR2009/001977 WO2009128661A2 (ko) 2008-04-18 2009-04-16 신규 벤조옥사진 벤즈이미다졸 유도체, 이를 포함하는 약학 조성물 및 이의 용도

Country Status (12)

Country Link
US (1) US8362012B2 (ko)
EP (1) EP2264031B1 (ko)
JP (1) JP5372138B2 (ko)
KR (1) KR101252334B1 (ko)
CN (1) CN101983197B (ko)
AU (1) AU2009236824B2 (ko)
CA (1) CA2719515C (ko)
ES (1) ES2539290T3 (ko)
MY (1) MY152022A (ko)
NZ (1) NZ587771A (ko)
TW (1) TWI395747B (ko)
WO (1) WO2009128661A2 (ko)

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TW200948807A (en) 2009-12-01
AU2009236824A2 (en) 2010-10-28
KR101252334B1 (ko) 2013-04-08
US8362012B2 (en) 2013-01-29
CN101983197A (zh) 2011-03-02
AU2009236824B2 (en) 2012-02-16
JP2011518152A (ja) 2011-06-23
EP2264031A4 (en) 2012-06-13
KR20090110792A (ko) 2009-10-22
US20110086849A1 (en) 2011-04-14
WO2009128661A2 (ko) 2009-10-22
AU2009236824A1 (en) 2009-10-22
TWI395747B (zh) 2013-05-11
CN101983197B (zh) 2015-04-22
MY152022A (en) 2014-08-15
EP2264031A2 (en) 2010-12-22
CA2719515C (en) 2013-11-05
JP5372138B2 (ja) 2013-12-18
EP2264031B1 (en) 2015-04-15
NZ587771A (en) 2011-05-27
CA2719515A1 (en) 2009-10-22
ES2539290T3 (es) 2015-06-29

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