WO2009021007A1 - Methods and devices for desmopressin drug delivery - Google Patents

Methods and devices for desmopressin drug delivery Download PDF

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Publication number
WO2009021007A1
WO2009021007A1 PCT/US2008/072290 US2008072290W WO2009021007A1 WO 2009021007 A1 WO2009021007 A1 WO 2009021007A1 US 2008072290 W US2008072290 W US 2008072290W WO 2009021007 A1 WO2009021007 A1 WO 2009021007A1
Authority
WO
WIPO (PCT)
Prior art keywords
desmopressin
patient
blood
concentration
skin
Prior art date
Application number
PCT/US2008/072290
Other languages
English (en)
French (fr)
Inventor
Samuel Herschkowitz
Seymour Fein
Original Assignee
Serenity Pharmaceuticals Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Serenity Pharmaceuticals Corporation filed Critical Serenity Pharmaceuticals Corporation
Priority to KR1020147032761A priority Critical patent/KR20140143461A/ko
Priority to CA2695634A priority patent/CA2695634C/en
Priority to CN200880107384.XA priority patent/CN101801452B/zh
Priority to EP08797244A priority patent/EP2197532A1/en
Priority to RU2010108304/14A priority patent/RU2472539C2/ru
Priority to AU2008283929A priority patent/AU2008283929B2/en
Priority to BRPI0814986-0A2A priority patent/BRPI0814986A2/pt
Priority to KR1020107004939A priority patent/KR101522747B1/ko
Priority to JP2010520270A priority patent/JP5451613B2/ja
Publication of WO2009021007A1 publication Critical patent/WO2009021007A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/48—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for varying, regulating, indicating or limiting injection pressure
    • A61M5/482—Varying injection pressure, e.g. by varying speed of injection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Radiology & Medical Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
PCT/US2008/072290 2007-08-06 2008-08-06 Methods and devices for desmopressin drug delivery WO2009021007A1 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
KR1020147032761A KR20140143461A (ko) 2007-08-06 2008-08-06 데스모프레신 약물 전달을 위한 방법 및 장치
CA2695634A CA2695634C (en) 2007-08-06 2008-08-06 Methods and devices for desmopressin drug delivery
CN200880107384.XA CN101801452B (zh) 2007-08-06 2008-08-06 用于去氨加压素药物给送的设备
EP08797244A EP2197532A1 (en) 2007-08-06 2008-08-06 Methods and devices for desmopressin drug delivery
RU2010108304/14A RU2472539C2 (ru) 2007-08-06 2008-08-06 Способы и устройства для доставки препарата десмопрессина
AU2008283929A AU2008283929B2 (en) 2007-08-06 2008-08-06 Methods and devices for desmopressin drug delivery
BRPI0814986-0A2A BRPI0814986A2 (pt) 2007-08-06 2008-08-06 Métodos e dispositivos para a distribuição de fármaco desmopresina.
KR1020107004939A KR101522747B1 (ko) 2007-08-06 2008-08-06 데스모프레신 약물 전달을 위한 방법 및 장치
JP2010520270A JP5451613B2 (ja) 2007-08-06 2008-08-06 デスモプレシン薬物送達のための方法及びデバイス

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95415907P 2007-08-06 2007-08-06
US60/954,159 2007-08-06

Publications (1)

Publication Number Publication Date
WO2009021007A1 true WO2009021007A1 (en) 2009-02-12

Family

ID=39817151

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/072290 WO2009021007A1 (en) 2007-08-06 2008-08-06 Methods and devices for desmopressin drug delivery

Country Status (10)

Country Link
US (3) US8399410B2 (pt)
EP (1) EP2197532A1 (pt)
JP (3) JP5451613B2 (pt)
KR (2) KR101522747B1 (pt)
CN (1) CN101801452B (pt)
AU (1) AU2008283929B2 (pt)
BR (1) BRPI0814986A2 (pt)
CA (2) CA2695634C (pt)
RU (1) RU2472539C2 (pt)
WO (1) WO2009021007A1 (pt)

Cited By (11)

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US7799761B2 (en) 2002-05-07 2010-09-21 Allergan, Inc. Pharmaceutical compositions including low dosages of desmopressin
US8399410B2 (en) 2007-08-06 2013-03-19 Allergan, Inc. Methods and devices for desmopressin drug delivery
WO2014018223A1 (en) * 2012-07-27 2014-01-30 Wellesley Pharmaceuticals, Llc Pharmaceutical formulation for bedwetting and method of use thereof
US8703184B2 (en) 2010-07-08 2014-04-22 Wellesley Pharmaceuticals, Llc Delayed-release formulation for reducing the frequency of urination and method of use thereof
US9814753B2 (en) 2013-07-23 2017-11-14 Serenity Pharmaceuticals Llc Methods and compositions comprising desmopressin in combination with a beta-3-adrenergic receptor agonist
US9974826B2 (en) 2008-05-21 2018-05-22 Ferring B.V. Methods comprising desmopressin
US10137167B2 (en) 2008-05-21 2018-11-27 Ferring B.V. Methods comprising desmopressin
US10278925B2 (en) 2012-01-04 2019-05-07 Wellesley Pharmaceuticals, Llc Delayed-release formulations, methods of making and use thereof
US10286033B2 (en) 2014-11-20 2019-05-14 Serenity Pharmaceuticals, Llc Methods and compositions comprising desmopressin in combination with an alpha-adrenergic receptor antagonist
US11419914B2 (en) 2009-06-18 2022-08-23 Serenity Pharmaceuticals Llc Safe desmopressin administration
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin

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US9474685B2 (en) * 2011-09-28 2016-10-25 Sure-Shot Medical Device Inc. Apparatus for localized dermatological treatment
JP6277953B2 (ja) * 2012-02-29 2018-02-14 凸版印刷株式会社 針状体の製造方法
JP2015510956A (ja) 2012-03-14 2015-04-13 メディパックス インコーポレイテッド 過剰反応性分子を含むスマートポリマー材料
CA2901568C (en) 2013-02-28 2021-02-16 Kimberly-Clark Worldwide, Inc. Transdermal drug delivery device
AU2014293140A1 (en) * 2013-07-23 2016-03-03 Serenity Pharmaceuticals Llc Methods and compositions comprising desmopressin in combination with a 5-alpha reductase inhibitor
JPWO2016006409A1 (ja) * 2014-07-09 2017-04-27 凸版印刷株式会社 液剤注入装置
US10537723B2 (en) * 2014-09-11 2020-01-21 Hisamitsu Pharmaceutical Co., Inc. Microneedle device
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JP7008709B2 (ja) 2016-12-16 2022-01-25 ソレント・セラピューティクス・インコーポレイテッド 制御アセンブリを有する流体送達装置及びその使用方法
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USD836774S1 (en) 2016-12-16 2018-12-25 Sorrento Therapeutics, Inc. Cartridge for a fluid delivery apparatus
JP6977258B2 (ja) * 2016-12-20 2021-12-08 株式会社リコー 中空構造体
KR101858394B1 (ko) * 2017-03-31 2018-05-15 부산대학교 산학협력단 경피형 약물 전달 패치, 경피형 약물 전달 시스템 및 약물 투여량을 모니터링하는 방법
JP6884037B2 (ja) * 2017-05-29 2021-06-09 株式会社ジェイメック パルス電圧治療装置
CN107260245A (zh) * 2017-07-08 2017-10-20 徐欣欣 一种凝血功能障碍患者的紧急辅助止血装置
EP3730141A4 (en) * 2017-12-21 2021-10-13 Kyorin Pharmaceutical Co., Ltd. THERAPEUTIC FOR NIGHTLY POLLAKISURIA
KR101891465B1 (ko) * 2018-03-16 2018-08-23 부산대학교 산학협력단 경피형 약물 전달 패치, 경피형 약물 전달 시스템 및 약물 투여량을 모니터링하는 방법
CN108939284B (zh) * 2018-08-16 2023-08-08 厦门薇针医药科技有限公司 可溶解微针注射装置
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