WO2006079614A3 - Copolyhydroxyalkylglutamines fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques - Google Patents

Copolyhydroxyalkylglutamines fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques Download PDF

Info

Publication number
WO2006079614A3
WO2006079614A3 PCT/EP2006/050369 EP2006050369W WO2006079614A3 WO 2006079614 A3 WO2006079614 A3 WO 2006079614A3 EP 2006050369 W EP2006050369 W EP 2006050369W WO 2006079614 A3 WO2006079614 A3 WO 2006079614A3
Authority
WO
WIPO (PCT)
Prior art keywords
copolyhydroxyalkylglutamines
novel
vectorisation
principles
active principles
Prior art date
Application number
PCT/EP2006/050369
Other languages
English (en)
Other versions
WO2006079614A2 (fr
Inventor
Remi Soula
You-Ping Chan
Original Assignee
Flamel Tech Sa
Remi Soula
You-Ping Chan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flamel Tech Sa, Remi Soula, You-Ping Chan filed Critical Flamel Tech Sa
Priority to BRPI0607130-9A priority Critical patent/BRPI0607130A2/pt
Priority to JP2007552626A priority patent/JP2008528543A/ja
Priority to CA002596147A priority patent/CA2596147A1/fr
Priority to MX2007009029A priority patent/MX2007009029A/es
Priority to EP06707793A priority patent/EP1848411A2/fr
Priority to AU2006208739A priority patent/AU2006208739A1/en
Priority to US11/883,223 priority patent/US20110044930A1/en
Publication of WO2006079614A2 publication Critical patent/WO2006079614A2/fr
Publication of WO2006079614A3 publication Critical patent/WO2006079614A3/fr
Priority to IL184863A priority patent/IL184863A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G23/00—Compounds of titanium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/88—Polyamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00—Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/48—Polymers modified by chemical after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L77/00—Compositions of polyamides obtained by reactions forming a carboxylic amide link in the main chain; Compositions of derivatives of such polymers
    • C08L77/04—Polyamides derived from alpha-amino carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Nanotechnology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Geology (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Environmental & Geological Engineering (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Polyamides (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne des nouveaux matériaux à base de polyaminoacides modifiés, biodégradables, utiles notamment pour la vectorisation de principe(s) actif(s) (PA). L'invention vise aussi de nouvelles compositions pharmaceutiques, cosmétiques, diététiques ou phytosanitaires à base de ces polyaminoacides. Le but de l'invention est de fournir une nouvelle matière première polymère, susceptible d'être utilisée pour la vectorisation de PA et permettant de satisfaire de manière optimale à toutes les spécifications requises en l'espèce : biocompatibilité, biodégradabilité, aptitude à s'associer facilement avec de nombreux principes actifs ou à les solubiliser, et à libérer ces principes actifs in vivo. Ce but est atteint par la présente invention qui concerne des nouveaux copolyhydroxyalkylglutamines, comprenant des unités glutamines et éventuellement des unités glutamates, et qui sont porteuses de groupements hydrophobes comportant de 8 à 30 atomes de carbone. Ces copolyhydroxyalkylglutamines sont amphiphiles et sont aptes à se transformer aisément et économiquement en particules de vectorisation de principes actifs, ces particules étant elles même propres à former des suspensions colloïdales aqueuses stables.
PCT/EP2006/050369 2005-01-27 2006-01-23 Copolyhydroxyalkylglutamines fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques WO2006079614A2 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
BRPI0607130-9A BRPI0607130A2 (pt) 2005-01-27 2006-01-23 copolihidroxi-alquil-glutaminas funcionalizadas por grupamentos hidrofóbicos e as respectivas aplicações, notadamente terapêuticas
JP2007552626A JP2008528543A (ja) 2005-01-27 2006-01-23 疎水基で官能基化されたコポリヒドロキシアルキルグルタミン、および特に治療におけるその使用
CA002596147A CA2596147A1 (fr) 2005-01-27 2006-01-23 Copolyhydroxyalkylglutamines fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques
MX2007009029A MX2007009029A (es) 2005-01-27 2006-01-23 Copolihidroxialquilglutaminas que estan funcionalizadas con grupos hidrofobicos, y aplicaciones de las mismas, tal como en terapeuticas.
EP06707793A EP1848411A2 (fr) 2005-01-27 2006-01-23 Copolyhydroxyalkylglutamines fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques
AU2006208739A AU2006208739A1 (en) 2005-01-27 2006-01-23 Copolyhydroxyalkylglutamines which are functionalised with hydrophobic groups and applications thereof, such as in therapeutics
US11/883,223 US20110044930A1 (en) 2005-01-27 2006-01-23 Copolyhydroxyalkylglutamines functionalised with hydrophobic groups, and uses thereof, especially in therapeutics
IL184863A IL184863A0 (en) 2005-01-27 2007-07-26 Copolyhydroxyalkylglutamines which are functionalised with hydrophobic groups and applications thereof, such as in therapeutics

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0550231 2005-01-27
FR0550231A FR2881140B1 (fr) 2005-01-27 2005-01-27 Copolyhydroxyalkylglutamines fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques

Publications (2)

Publication Number Publication Date
WO2006079614A2 WO2006079614A2 (fr) 2006-08-03
WO2006079614A3 true WO2006079614A3 (fr) 2007-06-21

Family

ID=34955198

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/050369 WO2006079614A2 (fr) 2005-01-27 2006-01-23 Copolyhydroxyalkylglutamines fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques

Country Status (13)

Country Link
US (1) US20110044930A1 (fr)
EP (1) EP1848411A2 (fr)
JP (1) JP2008528543A (fr)
KR (1) KR20070101337A (fr)
CN (1) CN101151023A (fr)
AU (1) AU2006208739A1 (fr)
BR (1) BRPI0607130A2 (fr)
CA (1) CA2596147A1 (fr)
FR (1) FR2881140B1 (fr)
IL (1) IL184863A0 (fr)
MX (1) MX2007009029A (fr)
WO (1) WO2006079614A2 (fr)
ZA (1) ZA200707079B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2822834B1 (fr) 2001-04-02 2005-02-25 Flamel Tech Sa Suspension colloidale de nanoparticules a base de copolymeres amphiphile pour la vectorisation de principes actifs et leur mode de preparation
FR2840614B1 (fr) 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
FR2862536B1 (fr) 2003-11-21 2007-11-23 Flamel Tech Sa Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s), ainsi que leurs applications notamment therapeutiques
CN100443547C (zh) * 2007-03-15 2008-12-17 上海交通大学 聚(酰胺-胺)-聚(l-苄基-谷氨酸酯)纳米粒子的制备方法
FR2915683B1 (fr) * 2007-05-03 2009-08-07 Flamel Technologies Sa Formulations pharmaceutiques auto-precipitantes pour la liberation modifiee de principe actif
FR2915684B1 (fr) * 2007-05-03 2011-01-14 Flamel Tech Sa Particules a base de polyelectrolytes et de principe actif a liberation modifiee et formulations pharmaceutiques contenant ces particules
FR2968994B1 (fr) 2010-12-17 2012-12-28 Flamel Tech Sa Procede de preparation de nanoparticules
FR2968993B1 (fr) 2010-12-17 2012-12-28 Flamel Tech Sa Nanoparticules comportant au moins un actif et au moins deux polyelectrolytes
FR2975912B1 (fr) 2011-05-30 2013-06-14 Flamel Tech Sa Composition a liberation controlee de buprenorphine
BR112014016889A8 (pt) * 2012-01-09 2017-07-04 Adocia composição sob a forma de uma solução aquosa injetável, sujo ph está compreendido entre 6,0 e 8,0 e, formulação de dose unitária com ph compreendido entre 7 e 7,8
JP2019517560A (ja) * 2016-06-07 2019-06-24 アドシア ヒトグルカゴン及びコポリアミノ酸を含む注射用溶液の形態の組成物
CN108623802B (zh) * 2018-05-08 2021-01-08 四川大学 一种功能性聚氨基酸衍生物及其制备方法和应用
CN109730081A (zh) * 2019-02-26 2019-05-10 南京轩凯生物科技有限公司 一种农用杀菌剂组合物
CN113896236A (zh) * 2021-09-13 2022-01-07 常州市妇幼保健院 一种基于谷氨酰胺修饰的二氧化钛合成方法

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0179023A2 (fr) * 1984-10-19 1986-04-23 Battelle Memorial Institute Polypeptide biodégradable et son utilisation pour le relargage progressif de médicaments
WO1987003891A1 (fr) * 1985-12-19 1987-07-02 Battelle Memorial Institute Polypeptide synthetique biodegradable et son utilisation en therapeutique
FR2786098A1 (fr) * 1998-11-20 2000-05-26 Flamel Tech Sa Particules a base de polyaminoacide(s) et susceptibles d'etre utilisees comme vecteurs de principe(s) actif(s), suspension colloidale les comprenant et leurs procedes de fabrication
WO2002028521A1 (fr) * 2000-10-06 2002-04-11 Flamel Technologies Suspension colloïdale de particules submicroniques de vectorisation de principes actifs et leur mode de preparation
JP2002194078A (ja) * 2000-12-27 2002-07-10 Mitsui Chemicals Inc 重合体及びその製造方法
JP2002194080A (ja) * 2000-12-27 2002-07-10 Mitsui Chemicals Inc 重合体及びその製造方法
JP2003327693A (ja) * 2002-05-15 2003-11-19 Mitsuru Akashi 親−疎水性修飾ポリ（γ−グルタミン酸）
FR2843117A1 (fr) * 2002-07-30 2004-02-06 Flamel Tech Sa Polyaminoacides fonctionnalises par au moins un groupement hydrophobe et leurs applications notamment therapeutiques
FR2855521A1 (fr) * 2003-05-28 2004-12-03 Flamel Tech Sa Polyaminoacides fonctionnalises par au moins un groupement h ydrophobe et leurs applications notamment therapeutiques.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4351337A (en) * 1973-05-17 1982-09-28 Arthur D. Little, Inc. Biodegradable, implantable drug delivery device, and process for preparing and using the same
JPS60100516A (ja) * 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
KR940003548U (ko) * 1992-08-14 1994-02-21 김형술 세탁물 건조기
US6153193A (en) * 1993-04-28 2000-11-28 Supratek Pharma Inc. Compositions for targeting biological agents
FR2732218B1 (fr) * 1995-03-28 1997-08-01 Flamel Tech Sa Particules a base de polyaminoacide(s) et susceptibles d'etre utilisees comme vecteurs de principe(s) actif(s) et leurs procedes de preparation
FR2801226B1 (fr) * 1999-11-23 2002-01-25 Flamel Tech Sa Suspension colloidale de particules submicroniques de vectorisation de principes actifs et son mode de preparation
PE20020908A1 (es) * 2001-03-21 2002-10-26 Cell Therapeutics Inc Produccion recombinante de polimeros polianionicos y uso de de los mismos
US6676785B2 (en) * 2001-04-06 2004-01-13 Ebert Composites Corporation Method of clinching the top and bottom ends of Z-axis fibers into the respective top and bottom surfaces of a composite laminate
FR2840614B1 (fr) * 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0179023A2 (fr) * 1984-10-19 1986-04-23 Battelle Memorial Institute Polypeptide biodégradable et son utilisation pour le relargage progressif de médicaments
US4888398A (en) * 1984-10-19 1989-12-19 Battelle Memorial Institute Biodegradable polypeptide and the use thereof for the gradual release of drugs
WO1987003891A1 (fr) * 1985-12-19 1987-07-02 Battelle Memorial Institute Polypeptide synthetique biodegradable et son utilisation en therapeutique
FR2786098A1 (fr) * 1998-11-20 2000-05-26 Flamel Tech Sa Particules a base de polyaminoacide(s) et susceptibles d'etre utilisees comme vecteurs de principe(s) actif(s), suspension colloidale les comprenant et leurs procedes de fabrication
US6630171B1 (en) * 1998-11-20 2003-10-07 Flamel Technologies Particles based on polyamino-acid(s) and methods for preparing same
WO2002028521A1 (fr) * 2000-10-06 2002-04-11 Flamel Technologies Suspension colloïdale de particules submicroniques de vectorisation de principes actifs et leur mode de preparation
JP2002194078A (ja) * 2000-12-27 2002-07-10 Mitsui Chemicals Inc 重合体及びその製造方法
JP2002194080A (ja) * 2000-12-27 2002-07-10 Mitsui Chemicals Inc 重合体及びその製造方法
JP2003327693A (ja) * 2002-05-15 2003-11-19 Mitsuru Akashi 親−疎水性修飾ポリ（γ−グルタミン酸）
FR2843117A1 (fr) * 2002-07-30 2004-02-06 Flamel Tech Sa Polyaminoacides fonctionnalises par au moins un groupement hydrophobe et leurs applications notamment therapeutiques
WO2004013206A2 (fr) * 2002-07-30 2004-02-12 Flamel Technologies Polyaminoacides fonctionnalises par au moins un groupement hydrophobe et leurs applications notamment therapeutiques
FR2855521A1 (fr) * 2003-05-28 2004-12-03 Flamel Tech Sa Polyaminoacides fonctionnalises par au moins un groupement h ydrophobe et leurs applications notamment therapeutiques.

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DAEWOON SOHN, E.A.: "Self-Assembly of Substituted Polyglutamates on Solid Substrates : The Side-Chain Effect", LANGMUIR, vol. 15, no. 5, 1999, pages 1698 - 1702, XP002407263 *
DATABASE WPI Week 200274, Derwent World Patents Index; AN 2002-685440, XP002403347 *
DATABASE WPI Week 200275, Derwent World Patents Index; AN 2002-694010, XP002403346 *
DATABASE WPI Week 200425, Derwent World Patents Index; AN 2004-260230, XP002407276 *

Also Published As

Publication number Publication date
FR2881140A1 (fr) 2006-07-28
BRPI0607130A2 (pt) 2009-08-04
IL184863A0 (en) 2007-12-03
CA2596147A1 (fr) 2006-08-03
ZA200707079B (en) 2008-12-31
CN101151023A (zh) 2008-03-26
AU2006208739A1 (en) 2006-08-03
KR20070101337A (ko) 2007-10-16
WO2006079614A2 (fr) 2006-08-03
EP1848411A2 (fr) 2007-10-31
JP2008528543A (ja) 2008-07-31
US20110044930A1 (en) 2011-02-24
MX2007009029A (es) 2007-10-02
FR2881140B1 (fr) 2007-04-06

Similar Documents

Publication Publication Date Title
WO2006079614A3 (fr) Copolyhydroxyalkylglutamines fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques
WO2004013206A3 (fr) Polyaminoacides fonctionnalises par au moins un groupement hydrophobe et leurs applications notamment therapeutiques
Spiridon et al. Design, characterization and preliminary biological evaluation of new lignin-PLA biocomposites
WO2005033181A3 (fr) Homopolyaminoacides telecheliques fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques
ATE449806T1 (de) Mittels wasserabweisender implantate mit anionischer ladung funktionalisierte polyaminosäuren und anwendungen, wie etwa therapeutische anwendungen dafür
Kumar et al. Controlled biodegradation of polymers using nanoparticles and its application
MX2009011813A (es) Acidos poliglutamicos funcionalizados con grupos cationicos y grupos hidrofobicos y aplicaciones de los mismos, en particular aplicaciones terapeuticas de los mismos.
WO2007051923A3 (fr) Acides polyglutamiques fonctionnalises par des derives de l'histidine et des groupements hydrophobes et leurs applications notamment therapeutiques
Lei et al. Sol–gel derived nanoscale bioactive glass (NBG) particles reinforced poly (ε-caprolactone) composites for bone tissue engineering
Kucharska et al. Fabrication of in-situ foamed chitosan/β-TCP scaffolds for bone tissue engineering application
BR0311831A (pt) Poliaminoácidos funcionalizados pelo alfa-tocoferol e suas aplicações notadamente terapêuticas
Bonkovoski et al. Polyelectrolyte complexes of poly [(2-dimethylamino) ethyl methacrylate]/chondroitin sulfate obtained at different pHs: I. Preparation, characterization, cytotoxicity and controlled release of chondroitin sulfate
Diez-Pascual Tissue engineering bionanocomposites based on poly (propylene fumarate)
Prasad et al. Hydroxyapatite-poly (vinyl alcohol) core-shell nanoparticles for dual delivery of methotrexate and gemcitabine for bone cancer treatment
TW200730184A (en) Film-coated and/or granulated calcium-containing compounds and use thereof in pharmaceutical compositions
WO2007109069A3 (fr) Dérivés hydrophobes de polysaccharides biodégradables et utilisations de ceux-ci
WO2008104960A8 (fr) Compositions et/ou articles comprenant un matériau complexe à cyclodextrine
WO2008104954A3 (fr) Compositions et/ou articles comprenant une matière complexant la cyclodextrine
WO2008129106A3 (fr) Nanoparticules comprenant une cyclodextrine et une molécule biologiquement active et leurs applications
WO2011034765A3 (fr) Compositions assainissantes comprenant des polymères de liaison des mauvaises odeurs
EP2669269A3 (fr) Particules libérant de l'oxyde nitrique pour thérapie à base d'oxyde nitrique et applications biomédicales
WO2007038220A3 (fr) Materiau particulaire hybride organique-inorganique et compositions polymeres contenant celui-ci
WO2011034997A3 (fr) Compositions rafraîchissantes comprenant des polymères de liaison des mauvaises odeurs et des agents neutralisant les mauvaises odeurs
An et al. Influence of polymeric additives on the cohesion and mechanical properties of calcium phosphate cements
WO2006082328A3 (fr) Compositions comprenant des micro-organismes deshydrates, leurs procedes de preparation, et leurs utilisations

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: MX/a/2007/009029

Country of ref document: MX

Ref document number: 184863

Country of ref document: IL

WWE Wipo information: entry into national phase

Ref document number: 2007552626

Country of ref document: JP

Ref document number: 2596147

Country of ref document: CA

Ref document number: 5898/DELNP/2007

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 2006208739

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 1020077019053

Country of ref document: KR

WWE Wipo information: entry into national phase

Ref document number: 2006707793

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2006208739

Country of ref document: AU

Date of ref document: 20060123

Kind code of ref document: A

WWP Wipo information: published in national office

Ref document number: 2006208739

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 200680009864.3

Country of ref document: CN

WWP Wipo information: published in national office

Ref document number: 2006707793

Country of ref document: EP

ENP Entry into the national phase

Ref document number: PI0607130

Country of ref document: BR

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 11883223

Country of ref document: US