FR2968993B1 - Nanoparticules comportant au moins un actif et au moins deux polyelectrolytes - Google Patents

Nanoparticules comportant au moins un actif et au moins deux polyelectrolytes

Info

Publication number
FR2968993B1
FR2968993B1 FR1060684A FR1060684A FR2968993B1 FR 2968993 B1 FR2968993 B1 FR 2968993B1 FR 1060684 A FR1060684 A FR 1060684A FR 1060684 A FR1060684 A FR 1060684A FR 2968993 B1 FR2968993 B1 FR 2968993B1
Authority
FR
France
Prior art keywords
polyelectrolytes
nanoparticles
active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1060684A
Other languages
English (en)
Other versions
FR2968993A1 (fr
Inventor
Cecile Bonnet-Gonnet
Remi Meyrueix
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Flamel Technologies SA
Original Assignee
Flamel Technologies SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR1060684A priority Critical patent/FR2968993B1/fr
Application filed by Flamel Technologies SA filed Critical Flamel Technologies SA
Priority to EP11807787.4A priority patent/EP2651394A1/fr
Priority to US13/328,696 priority patent/US20120156256A1/en
Priority to CN2011800678423A priority patent/CN103370052A/zh
Priority to JP2013543958A priority patent/JP2014515003A/ja
Priority to PCT/IB2011/055728 priority patent/WO2012080987A1/fr
Priority to CA2821141A priority patent/CA2821141A1/fr
Publication of FR2968993A1 publication Critical patent/FR2968993A1/fr
Application granted granted Critical
Publication of FR2968993B1 publication Critical patent/FR2968993B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FR1060684A 2010-12-17 2010-12-17 Nanoparticules comportant au moins un actif et au moins deux polyelectrolytes Expired - Fee Related FR2968993B1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR1060684A FR2968993B1 (fr) 2010-12-17 2010-12-17 Nanoparticules comportant au moins un actif et au moins deux polyelectrolytes
US13/328,696 US20120156256A1 (en) 2010-12-17 2011-12-16 Nanoparticles having at least one active ingredient and at least two polyelectrolytes
CN2011800678423A CN103370052A (zh) 2010-12-17 2011-12-16 包括至少一种活性剂和至少两种聚电解质的纳米颗粒
JP2013543958A JP2014515003A (ja) 2010-12-17 2011-12-16 少なくとも１の活性剤及び反対の電荷の少なくとも２のポリアミノ酸を含むナノ粒子
EP11807787.4A EP2651394A1 (fr) 2010-12-17 2011-12-16 Nanoparticules comportant au moins un actif et au moins deux polyelectrolytes
PCT/IB2011/055728 WO2012080987A1 (fr) 2010-12-17 2011-12-16 Nanoparticules comportant au moins un actif et au moins deux polyelectrolytes
CA2821141A CA2821141A1 (fr) 2010-12-17 2011-12-16 Nanoparticules comportant au moins un actif et au moins deux polyamino acides de charge opposee

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1060684A FR2968993B1 (fr) 2010-12-17 2010-12-17 Nanoparticules comportant au moins un actif et au moins deux polyelectrolytes

Publications (2)

Publication Number Publication Date
FR2968993A1 FR2968993A1 (fr) 2012-06-22
FR2968993B1 true FR2968993B1 (fr) 2012-12-28

Family

ID=44461767

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1060684A Expired - Fee Related FR2968993B1 (fr) 2010-12-17 2010-12-17 Nanoparticules comportant au moins un actif et au moins deux polyelectrolytes

Country Status (7)

Country Link
US (1) US20120156256A1 (fr)
EP (1) EP2651394A1 (fr)
JP (1) JP2014515003A (fr)
CN (1) CN103370052A (fr)
CA (1) CA2821141A1 (fr)
FR (1) FR2968993B1 (fr)
WO (1) WO2012080987A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103341169B (zh) * 2013-07-04 2015-10-07 张峰 一种针对小分子亲水药物控释的包裹方法
JP6671300B2 (ja) * 2014-05-27 2020-03-25 アーティフィシャル セル テクノロジーズ インコーポレイテッド Ｔｆｆによる多層コーティング化コアの自動交互積層構築
WO2023077151A1 (fr) * 2021-11-01 2023-05-04 The Johns Hopkins University Facteurs de croissance régénératifs pour la réparation nerveuse, leurs procédés de préparation et méthodes de traitement les utilisant

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2732218B1 (fr) 1995-03-28 1997-08-01 Flamel Tech Sa Particules a base de polyaminoacide(s) et susceptibles d'etre utilisees comme vecteurs de principe(s) actif(s) et leurs procedes de preparation
US20030170313A1 (en) * 1997-10-09 2003-09-11 Ales Prokop Micro-particulate and nano-particulate polymeric delivery system
EP1098696B2 (fr) * 1998-07-15 2010-07-14 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Revetement polyelectrolytique de specimens biologiques
FR2786098B1 (fr) 1998-11-20 2003-05-30 Flamel Tech Sa Particules a base de polyaminoacide(s) et susceptibles d'etre utilisees comme vecteurs de principe(s) actif(s), suspension colloidale les comprenant et leurs procedes de fabrication
FR2801226B1 (fr) 1999-11-23 2002-01-25 Flamel Tech Sa Suspension colloidale de particules submicroniques de vectorisation de principes actifs et son mode de preparation
FR2840614B1 (fr) 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
FR2881140B1 (fr) 2005-01-27 2007-04-06 Flamel Technologies Sa Copolyhydroxyalkylglutamines fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques
CA2654593A1 (fr) * 2006-06-08 2007-12-13 Bayer Schering Pharma Aktiengesellschaft Nanoparticules polymeres solides fonctionnalisees pour applications diagnostiques et therapeutiques
FR2902007B1 (fr) * 2006-06-09 2012-01-13 Flamel Tech Sa Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s) ainsi que leurs applications notamment therapeutiques
FR2915748B1 (fr) 2007-05-03 2012-10-19 Flamel Tech Sa Acides polyglutamiques fonctionnalises par des groupes cationiques et des groupements hydrophobes et leurs applications, notamment therapeutiques
FR2915684B1 (fr) * 2007-05-03 2011-01-14 Flamel Tech Sa Particules a base de polyelectrolytes et de principe actif a liberation modifiee et formulations pharmaceutiques contenant ces particules

Also Published As

Publication number Publication date
JP2014515003A (ja) 2014-06-26
US20120156256A1 (en) 2012-06-21
CN103370052A (zh) 2013-10-23
FR2968993A1 (fr) 2012-06-22
EP2651394A1 (fr) 2013-10-23
WO2012080987A1 (fr) 2012-06-21
CA2821141A1 (fr) 2012-06-21

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20150831