WO2004085429A1 - Ｉ型コラーゲン及び／又はエラスチン産生促進用組成物 - Google Patents

Ｉ型コラーゲン及び／又はエラスチン産生促進用組成物 Download PDF

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Publication number
WO2004085429A1
WO2004085429A1 PCT/JP2004/003978 JP2004003978W WO2004085429A1 WO 2004085429 A1 WO2004085429 A1 WO 2004085429A1 JP 2004003978 W JP2004003978 W JP 2004003978W WO 2004085429 A1 WO2004085429 A1 WO 2004085429A1
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WIPO (PCT)
Prior art keywords
elastin
collagen
type
composition
skin
Prior art date
Application number
PCT/JP2004/003978
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English (en)
French (fr)
Inventor
Satoshi Miyata
Yoko Handa
Tetsuhito Sakurai
Original Assignee
Fancl Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fancl Corporation filed Critical Fancl Corporation
Priority to US10/550,224 priority Critical patent/US20060233738A1/en
Priority to JP2005504067A priority patent/JPWO2004085429A1/ja
Priority to CA002520057A priority patent/CA2520057A1/en
Publication of WO2004085429A1 publication Critical patent/WO2004085429A1/ja

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/70—Biological properties of the composition as a whole

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Toxicology (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

ヒト皮膚線維芽細胞のI型コラーゲン及び/又はエラスチンの産生を促進する組成物を提供することにより、皮膚のはりや弾力性を向上させ、しわやたるみの予防、防止、改善に十分に有効で、かつ、皮膚に対する安全性も高い皮膚老化防止用組成物を提供することを目的とする。本発明は、シリビン、シリジアニン、シリクリスチン、イソシリビンなどのフラボノリグナンの総称であるシリマリンを含有し、I型コラーゲン産生促進及び/又はエラスチン産生促進作用を有することを特徴とする組成物、組成物に含まれるシリマリンがシリマリン含有植物及び/又は植物抽出液由来であり、I型コラーゲン産生促進及び/又はエラスチン産生促進作用を有することを特徴とする組成物である。
PCT/JP2004/003978 2003-03-25 2004-03-23 Ｉ型コラーゲン及び／又はエラスチン産生促進用組成物 WO2004085429A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US10/550,224 US20060233738A1 (en) 2003-03-25 2004-03-23 Composition for promoting production of type 1 collagen and/or elastin
JP2005504067A JPWO2004085429A1 (ja) 2003-03-25 2004-03-23 Ｉ型コラーゲン及び／又はエラスチン産生促進用組成物
CA002520057A CA2520057A1 (en) 2003-03-25 2004-03-23 Composition for promoting production of type i collagen and/or elastin

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003083943 2003-03-25
JP2003-083943 2003-03-25

Publications (1)

Publication Number Publication Date
WO2004085429A1 true WO2004085429A1 (ja) 2004-10-07

Family

ID=33094981

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2004/003978 WO2004085429A1 (ja) 2003-03-25 2004-03-23 Ｉ型コラーゲン及び／又はエラスチン産生促進用組成物

Country Status (7)

Country Link
US (1) US20060233738A1 (ja)
JP (1) JPWO2004085429A1 (ja)
KR (1) KR20050114677A (ja)
CN (1) CN1761662A (ja)
CA (1) CA2520057A1 (ja)
TW (2) TWI256893B (ja)
WO (1) WO2004085429A1 (ja)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006265186A (ja) * 2005-03-24 2006-10-05 Fancl Corp シリマリン含有光老化防止剤キット
EP1772140A1 (de) * 2005-10-10 2007-04-11 Beiersdorf AG Kosmetische Formulierungen zur Verbesserung der Hautbarrierefunktion
WO2007039976A1 (ja) * 2005-10-03 2007-04-12 Fancl Corporation 異常タンパク質除去用組成物
JP2007099625A (ja) * 2005-09-30 2007-04-19 Ryukyu Bio Resource Kaihatsu:Kk 皮膚線維芽細胞増殖促進剤
JP2011157281A (ja) * 2010-01-29 2011-08-18 Fancl Corp コラーゲンゲル収縮剤
US8022038B2 (en) 2005-09-29 2011-09-20 Fancl Corporation Composition for acceleration of type I collagen production
JP2011219454A (ja) * 2010-03-24 2011-11-04 Fancl Corp 細胞間接着剤
JP2014141450A (ja) * 2012-12-26 2014-08-07 Nitta Gelatin Inc エラスチン産生促進剤
CN107766686A (zh) * 2017-12-06 2018-03-06 南京理工大学 基于matlab计算fgm薄板刚柔耦合动力学响应的仿真方法
WO2024053320A1 (ja) * 2022-09-09 2024-03-14 丸善製薬株式会社 Ｉ型コラーゲン産生促進剤及びｉ型コラーゲン産生促進用組成物、並びに骨強化剤及び骨強化用組成物

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* Cited by examiner, † Cited by third party
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WO2008140440A1 (en) * 2005-12-07 2008-11-20 Mmp International Development And Manufacturing Stable flavonoid solutions
RU2441877C2 (ru) * 2006-06-13 2012-02-10 Хеликс Байомедикс Инк. Тетрапептид, композиция (варианты) и способ стимуляции продукции коллагена фибробластом
WO2008100789A2 (en) 2007-02-16 2008-08-21 Benaroya Research Institute At Virginia Mason Compositions and methods for altering elastogenesis
TWI393780B (zh) * 2007-08-09 2013-04-21 Toyo Hakko Co Ltd A fermentation composition, a cosmetic composition, and the like
JP2009173584A (ja) * 2008-01-25 2009-08-06 Fancl Corp シリビン配糖体含有皮膚外用組成物
WO2010062762A2 (en) * 2008-11-03 2010-06-03 Dermachip Inc. Compositions and methods for reducing the signs of aging of the skin
JP5647428B2 (ja) * 2009-04-24 2014-12-24 株式会社ファンケル シリビン配糖体水溶液及び皮膚外用組成物
KR20100117520A (ko) * 2009-04-24 2010-11-03 가부시키가이샤환케루 실리빈 배당체 수용액 및 피부 외용 조성물
EP2658522B1 (en) * 2010-12-30 2019-07-31 Mary Kay Inc. Multi-purpose cosmetic compositions
CN102178629B (zh) * 2011-04-19 2013-03-06 窦建国 一种水飞蓟精油健肤霜及其制备方法
KR102044562B1 (ko) * 2011-05-10 2019-11-13 마리 케이 인코포레이티드 화장 조성물
CN103284897B (zh) * 2012-01-27 2018-02-09 玫琳凯有限公司 化妆品制剂
US8877259B2 (en) * 2012-02-09 2014-11-04 Mary Kay Inc. Cosmetic formulation
JP5945142B2 (ja) * 2012-03-27 2016-07-05 株式会社 資生堂 しわ改善効果について化粧料を評価する方法
US20170326062A1 (en) 2016-05-13 2017-11-16 Yi-Chun Lin Compositions for skin application
WO2019060852A2 (en) * 2017-09-22 2019-03-28 Jeff Ochampaugh TREATMENT OF POWDERED SEEDS WITH LOW DUST CONTENT
CN110317774A (zh) * 2018-03-29 2019-10-11 玛旺干细胞医学生物科技股份有限公司 中草药的水性萃出物及其组合物与用途
KR102500786B1 (ko) * 2018-04-02 2023-02-17 애경산업(주) 피부볼륨감 증진 또는 피부탄력 증진용 피부외용제 조성물
KR102124065B1 (ko) * 2018-08-17 2020-06-17 서울대학교산학협력단 식물 추출물을 함유하는 피부 주름 개선용 조성물
CN113453674A (zh) * 2019-02-21 2021-09-28 株式会社医择 I型胶原蛋白或弹性蛋白的产生促进剂
CN110812318B (zh) * 2019-11-18 2022-04-19 诺恩诺德医学研究院(北京)有限公司 用于化妆品原料的优化的成纤维细胞提取物的制备方法

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JP2948818B2 (ja) * 1987-07-10 1999-09-13 インデナ エス．ピー．エイ． フラバノリグナンとリン脂質との錯体を含有する薬用及び化粧用組成物
JP2002173424A (ja) * 2000-12-04 2002-06-21 Maruzen Pharmaceut Co Ltd マトリックスメタロプロテアーゼ阻害剤
JP2002226323A (ja) * 2001-02-02 2002-08-14 Maruzen Pharmaceut Co Ltd コラーゲン産生促進剤、コラゲナーゼ阻害剤、線維芽細胞増殖作用剤、エラスターゼ阻害剤、エストロゲン様作用剤、皮膚化粧料並びに美容用飲食品
JP2003048846A (ja) * 2001-07-31 2003-02-21 Koei Kogyo Kk コラゲナーゼ阻害剤及び抗老化用化粧料
JP2003002813A (ja) * 2001-11-07 2003-01-08 Naris Cosmetics Co Ltd 皮膚組成物

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006265186A (ja) * 2005-03-24 2006-10-05 Fancl Corp シリマリン含有光老化防止剤キット
US8022038B2 (en) 2005-09-29 2011-09-20 Fancl Corporation Composition for acceleration of type I collagen production
JP2007099625A (ja) * 2005-09-30 2007-04-19 Ryukyu Bio Resource Kaihatsu:Kk 皮膚線維芽細胞増殖促進剤
WO2007039976A1 (ja) * 2005-10-03 2007-04-12 Fancl Corporation 異常タンパク質除去用組成物
US20110003760A1 (en) * 2005-10-03 2011-01-06 Fancl Corporation Abnormal protein removing method
TWI381834B (zh) * 2005-10-03 2013-01-11 Fancl Corp Abnormal protein removal composition
EP1772140A1 (de) * 2005-10-10 2007-04-11 Beiersdorf AG Kosmetische Formulierungen zur Verbesserung der Hautbarrierefunktion
JP2011157281A (ja) * 2010-01-29 2011-08-18 Fancl Corp コラーゲンゲル収縮剤
JP2011219454A (ja) * 2010-03-24 2011-11-04 Fancl Corp 細胞間接着剤
JP2014141450A (ja) * 2012-12-26 2014-08-07 Nitta Gelatin Inc エラスチン産生促進剤
CN107766686A (zh) * 2017-12-06 2018-03-06 南京理工大学 基于matlab计算fgm薄板刚柔耦合动力学响应的仿真方法
CN107766686B (zh) * 2017-12-06 2021-04-16 南京理工大学 基于matlab计算fgm薄板刚柔耦合动力学响应的仿真方法
WO2024053320A1 (ja) * 2022-09-09 2024-03-14 丸善製薬株式会社 Ｉ型コラーゲン産生促進剤及びｉ型コラーゲン産生促進用組成物、並びに骨強化剤及び骨強化用組成物

Also Published As

Publication number Publication date
TW200423961A (en) 2004-11-16
CN1761662A (zh) 2006-04-19
KR20050114677A (ko) 2005-12-06
TWI256893B (en) 2006-06-21
JPWO2004085429A1 (ja) 2006-06-29
TW200505496A (en) 2005-02-16
US20060233738A1 (en) 2006-10-19
CA2520057A1 (en) 2004-10-07

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