WO2004000861A1 - 結晶状マルチトールの製造方法 - Google Patents
結晶状マルチトールの製造方法 Download PDFInfo
- Publication number
- WO2004000861A1 WO2004000861A1 PCT/JP2003/007613 JP0307613W WO2004000861A1 WO 2004000861 A1 WO2004000861 A1 WO 2004000861A1 JP 0307613 W JP0307613 W JP 0307613W WO 2004000861 A1 WO2004000861 A1 WO 2004000861A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- maltitol
- kneading
- cooling
- aqueous solution
- weight
- Prior art date
Links
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 title claims abstract description 53
- 235000010449 maltitol Nutrition 0.000 title claims abstract description 44
- 239000000845 maltitol Substances 0.000 title claims abstract description 44
- 229940035436 maltitol Drugs 0.000 title claims abstract description 44
- 238000000034 method Methods 0.000 title claims abstract description 18
- 238000004898 kneading Methods 0.000 claims abstract description 35
- 239000007787 solid Substances 0.000 claims abstract description 20
- 238000001816 cooling Methods 0.000 claims abstract description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 17
- 238000010298 pulverizing process Methods 0.000 claims abstract description 8
- 239000007864 aqueous solution Substances 0.000 claims description 21
- 238000004519 manufacturing process Methods 0.000 claims description 16
- 239000013078 crystal Substances 0.000 abstract description 14
- 239000011369 resultant mixture Substances 0.000 abstract 2
- 238000007711 solidification Methods 0.000 abstract 2
- 230000008023 solidification Effects 0.000 abstract 2
- 239000002994 raw material Substances 0.000 description 40
- 230000015572 biosynthetic process Effects 0.000 description 3
- 238000002425 crystallisation Methods 0.000 description 3
- 230000008025 crystallization Effects 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 238000001035 drying Methods 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000010411 cooking Methods 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 235000012149 noodles Nutrition 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/33—Artificial sweetening agents containing sugars or derivatives
- A23L27/34—Sugar alcohols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C13—SUGAR INDUSTRY
- C13B—PRODUCTION OF SUCROSE; APPARATUS SPECIALLY ADAPTED THEREFOR
- C13B30/00—Crystallisation; Crystallising apparatus; Separating crystals from mother liquors ; Evaporating or boiling sugar juice
- C13B30/02—Crystallisation; Crystallising apparatus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Definitions
- the present invention relates to a method for producing crystalline maltitol.
- Conventional technology
- Maltitol is hardly digested and absorbed in the digestive tract and is hardly fermented by oral bacteria, so it is used as a sweetener for low calorie foods, diet foods, low carious foods, and for patients with diabetes.
- maltitol has a problem that it is inconvenient to handle because the dried product remarkably absorbs moisture, deliquesces easily, and hardly turns into powder.
- Japanese Patent Publication No. 7-144953 discloses that a maltitol aqueous solution is continuously supplied to an extruder having an elongated cooling and kneading zone, and is cooled and kneaded in the presence of seed crystals to form maltitol magma.
- a method for producing a multi-tol honey-containing crystal by continuously extruding from a extrusion nozzle after being formed.
- a first maltitol aqueous solution is supplied to a kneading apparatus, kneaded and cooled, and then the first maltitol aqueous solution is mixed with a high solid content.
- the present invention is achieved by a method for producing a state of maltitol (hereinafter, may be referred to as a first invention).
- a multitolu aqueous solution is supplied to a kneading apparatus to be kneaded and cooled, then water is added, and then kneading and cooling are continued.
- a method for producing crystalline maltitol characterized in that a plastic mass is produced by cooling, the plastic mass is cooled, solidified, and then pulverized (hereinafter sometimes referred to as the second invention). Achieved by Preferred embodiments of the invention
- the first maltitol aqueous solution (hereinafter, referred to as the first raw material) supplied to the kneading apparatus has a relatively low solid content
- the second maltitol aqueous solution (hereinafter, the second raw material) is supplied.
- the second maltitol aqueous solution has a higher solid content than the first raw material.
- the first raw material is preferably a maltitol aqueous solution having a solid content of 70 to 97% by weight and a purity of 88% by weight or more, and a solid content of 93 to 96% by weight and a purity of 90% by weight or more. Is more preferred.
- the second raw material an aqueous maltitol solution having a solid content of 97.5 to 99.5% by weight and a purity of 88% by weight or more is used.
- a maltitol aqueous solution having a solid content of 98 to 99% by weight and a purity of 90% by weight or more is more preferable.
- the supply rates of the first and second raw materials differ depending on the type and capacity of the kneading apparatus to be used, and thus need to be set as appropriate.However, the first and second raw materials are set so that the production efficiency is optimal in each kneading apparatus.
- the feed rate of the second raw material may be set. Also, the feed rates of the first and second raw materials need not be the same, and they may be fed at different rates. For example, KRC Kneader S2 (Kurimoto Tetsusho Co., Ltd.) is kneaded.
- the feed rate of the first raw material is preferably about 0.1 to 6.0 kgZhr
- the feed rate of the second raw material is preferably about 0.1 to 15 kg / hr.
- the jacket temperature of the kneading device at the time of feeding the raw material may be adjusted to a temperature at which the generated heat of crystallization can be removed, and when the KRC Nieder S2 (Kurimoto Tetsusho Co., Ltd.) is used. Is preferably 110 ° C. or lower, more preferably 95 ° C. or lower.
- the jacket temperature may be set at the time of supplying the first and second raw materials, respectively, depending on the degree of generation of heat of crystallization.
- the temperature at which the raw material is supplied to the kneading apparatus is preferably a temperature at which maltitol crystals do not precipitate. Considering that the higher the fluidity, the easier it is to handle, and the ease of adjustment in forming the plastic mass, etc., the first raw material is approximately 90 to 120 ° C, and the second raw material is 12 The temperature is preferably from 0 to 140 ° C.
- the switching from the first raw material to the second raw material is performed after the first raw material is put into the kneading device, and after the formation of a white opaque plastic mass is confirmed in the kneading device or from the discharge portion of the kneading device. It is preferred to do so. By performing this switching, the production efficiency of crystalline maltitol is improved.
- the aqueous solution of maltitol as a raw material preferably has a solid content of 97.5 to 99.5% by weight and a purity of 88% by weight or more, and a solid content of 98 to 99% by weight. Those having a purity of 90% by weight or more are more preferable.
- the feed rate of the aqueous maltitol solution is the feed rate of the first raw material in the first invention. Same as for degrees.
- the supply rate of the raw material can be changed to a rate similar to the supply rate of the second raw material in the first invention after a water adding step described later. It is preferable to switch the feed rate of the raw material after the formation of a white opaque plastic mass is confirmed from the kneading apparatus or from the discharge portion of the kneading apparatus.
- water is added after the raw material is supplied.
- the water can be water, such as tap water, but it is preferred to use ion exchange water to produce a pure, crystalline, multi-crystal.
- the amount of water to be added is preferably about 1.0 to 7.0 parts by weight with respect to 100 parts by weight of the aqueous solution of the maltitol.
- the operation of adding water can be performed several times to over a dozen times depending on the degree of formation of crystalline maltitol. Further, it can be continuously or intermittently added into the kneading apparatus using a pump or the like.
- the timing of adding water depends on the kneading equipment used, but it is sufficient to add the water after the raw material has sufficiently spread inside the kneading equipment, for example, after confirming that the raw material liquid is discharged from the outlet.
- the jacket temperature of the kneading apparatus is the same as that of the first invention, but may be changed before and after the step of adding water.
- the raw material is prepared by concentrating a maltitol aqueous solution having a solid content of about 70% by weight. At that time, if the water is removed by heating under normal pressure, the aqueous solution of the multitoll may be colored. Therefore, it is preferable to perform the concentration under reduced pressure. Since the use of colored raw materials may hinder the production of the desired crystalline maltitol, it is important to prepare raw materials that are as colorless and transparent as possible.
- the kneading apparatus that can be used in the present invention may be any type of open type, closed type, batch type, or continuous type as long as it can perform kneading and cooling at the same time, and is not particularly limited.
- a material that can be continuously extruded from the discharge port is preferable.
- Examples of such a kneading apparatus include an extruder, a continuous feeder, a mixtron, a kneedex and the like. Among them, Extruder is more preferably used.
- extruders such as KR C Kneader (manufactured by Kurimoto Co., Ltd.), food-use twin-screw extruder (manufactured by Nihon Steel Works), and twin-screw cooking extruder (manufactured by W & P) are listed.
- KR C Kneader manufactured by Kurimoto Co., Ltd.
- food-use twin-screw extruder manufactured by Nihon Steel Works
- twin-screw cooking extruder manufactured by W & P
- the shape can be any shape such as a needle shape, a ribbon shape, a rod shape, and a plate shape. Taking into account the subsequent steps such as cooling and pulverization, it is preferable to discharge the noodles or ripons.
- the perforated plate attached to the discharge port one having a hole diameter of about 2 to 5 mm and a porosity of about 10 to 40% is preferably used.
- the method of cooling is not particularly limited, for example, a method of directly applying cold air to the plastic mass discharged from the kneading apparatus, a method of leaving the plastic mass at room temperature, a method of cooling to about room temperature with a cool air on a metal mesh belt, and the like are employed. it can.
- the obtained crystalline maltitol can be made into powder or granules by pulverization without a drying step.
- the method of pulverization and granulation is not particularly limited. Conventional mills and granulators can be used. If necessary, the obtained powder or granule may be dried by a usual drying method.
- the feed rate of the second raw material was set at 8 kg Zhr, and the jacket temperature was set at 55 C. The noodle-like plastic mass was discharged stably.
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Saccharide Compounds (AREA)
Abstract
Description
Claims
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE60333467T DE60333467D1 (de) | 2002-06-19 | 2003-06-16 | Verfahren zur herstellung von kristallinem maltit |
AU2003278644A AU2003278644B2 (en) | 2002-06-19 | 2003-06-16 | Process for producing crystalline maltitol |
KR1020047017759A KR100889972B1 (ko) | 2002-06-19 | 2003-06-16 | 결정상 말티톨의 제조 방법 |
US10/517,451 US20050220959A1 (en) | 2002-06-19 | 2003-06-16 | Process for producing crystalline maltitol |
AT03741117T ATE474846T1 (de) | 2002-06-19 | 2003-06-16 | Verfahren zur herstellung von kristallinem maltit |
CA2489912A CA2489912C (en) | 2002-06-19 | 2003-06-16 | Production method of crystalline maltitol |
JP2004515495A JP4212103B2 (ja) | 2002-06-19 | 2003-06-16 | 結晶状マルチトールの製造方法 |
EP03741117A EP1553100B1 (en) | 2002-06-19 | 2003-06-16 | Process for producing crystalline maltitol |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002-178319 | 2002-06-19 | ||
JP2002178319 | 2002-06-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2004000861A1 true WO2004000861A1 (ja) | 2003-12-31 |
Family
ID=29996516
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2003/007613 WO2004000861A1 (ja) | 2002-06-19 | 2003-06-16 | 結晶状マルチトールの製造方法 |
Country Status (10)
Country | Link |
---|---|
US (1) | US20050220959A1 (ja) |
EP (1) | EP1553100B1 (ja) |
JP (1) | JP4212103B2 (ja) |
KR (1) | KR100889972B1 (ja) |
CN (1) | CN1307189C (ja) |
AT (1) | ATE474846T1 (ja) |
AU (1) | AU2003278644B2 (ja) |
CA (1) | CA2489912C (ja) |
DE (1) | DE60333467D1 (ja) |
WO (1) | WO2004000861A1 (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100654622B1 (ko) * | 2005-06-07 | 2006-12-08 | 주식회사 신동방씨피 | 고순도 분말 말티톨의 제조방법 |
US8168779B2 (en) * | 2006-07-06 | 2012-05-01 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Anhydrous crystalline β-maltose, its preparation and uses |
FR2929512B1 (fr) * | 2008-04-08 | 2010-12-31 | Roquette Freres | Composition pulverulente de maltitol cristallise de grande fluidite et non mottante |
CN101486741B (zh) * | 2008-12-15 | 2011-12-14 | 山东福田投资有限公司 | 一种连续生产结晶麦芽糖醇的工艺 |
EP2668851B1 (en) | 2012-05-29 | 2016-03-23 | Ueno Fine Chemicals Industry, Ltd. | Liver function-improving agent |
CN104311610B (zh) * | 2014-11-06 | 2017-03-08 | 山东绿健生物技术有限公司 | 一种快速制备粒状乳糖醇的方法 |
CN110776539A (zh) * | 2019-12-04 | 2020-02-11 | 浙江华康药业股份有限公司 | 一种控制麦芽糖醇结晶粒度的方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0202165A1 (fr) * | 1985-05-15 | 1986-11-20 | Roquette FrÀ¨res | Procédé et installation de production de maltitol cristallisé |
JPH06234786A (ja) * | 1993-02-09 | 1994-08-23 | Towa Kasei Kogyo Kk | マルチトールスラリーの連続的製造方法 |
JPH09132587A (ja) * | 1995-11-08 | 1997-05-20 | Towa Chem Ind Co Ltd | 結晶マルチトールの製造方法 |
EP0937733A2 (en) * | 1998-01-27 | 1999-08-25 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | A method for the continuous manufacture of anhydrous crystalline maltitol and a manufacturing apparatus therefor |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4458362A (en) * | 1982-05-13 | 1984-07-03 | Teledyne Industries, Inc. | Automatic time domain equalization of audio signals |
US4683590A (en) * | 1985-03-18 | 1987-07-28 | Nippon Telegraph And Telphone Corporation | Inverse control system |
US4888808A (en) * | 1987-03-23 | 1989-12-19 | Matsushita Electric Industrial Co., Ltd. | Digital equalizer apparatus enabling separate phase and amplitude characteristic modification |
AU643528B2 (en) * | 1990-06-25 | 1993-11-18 | Mitsubishi Shoji Foodtech Co., Ltd. | Molasses-containing maltitol crystal and production thereof |
US5583215A (en) | 1990-06-25 | 1996-12-10 | Towa Chemical Industry Co., Ltd. | Crystalline mixture solid containing maltitol and a process for preparing it |
GB9026906D0 (en) * | 1990-12-11 | 1991-01-30 | B & W Loudspeakers | Compensating filters |
CA2091616C (en) * | 1992-03-17 | 2002-11-26 | Ryuzo Ueno | Method for manufacturing powdery crystalline maltitol |
DE4332804C2 (de) * | 1993-09-27 | 1997-06-05 | Klippel Wolfgang | Adaptive Korrekturschaltung für elektroakustische Schallsender |
JP3602903B2 (ja) * | 1995-05-02 | 2004-12-15 | 東和化成工業株式会社 | 結晶マルチトール及びそれを含有する含蜜結晶の製造方法 |
-
2003
- 2003-06-16 AT AT03741117T patent/ATE474846T1/de not_active IP Right Cessation
- 2003-06-16 KR KR1020047017759A patent/KR100889972B1/ko active IP Right Grant
- 2003-06-16 JP JP2004515495A patent/JP4212103B2/ja not_active Expired - Fee Related
- 2003-06-16 CA CA2489912A patent/CA2489912C/en not_active Expired - Fee Related
- 2003-06-16 DE DE60333467T patent/DE60333467D1/de not_active Expired - Lifetime
- 2003-06-16 US US10/517,451 patent/US20050220959A1/en not_active Abandoned
- 2003-06-16 CN CNB038141329A patent/CN1307189C/zh not_active Expired - Fee Related
- 2003-06-16 AU AU2003278644A patent/AU2003278644B2/en not_active Ceased
- 2003-06-16 WO PCT/JP2003/007613 patent/WO2004000861A1/ja active Application Filing
- 2003-06-16 EP EP03741117A patent/EP1553100B1/en not_active Expired - Lifetime
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0202165A1 (fr) * | 1985-05-15 | 1986-11-20 | Roquette FrÀ¨res | Procédé et installation de production de maltitol cristallisé |
JPH06234786A (ja) * | 1993-02-09 | 1994-08-23 | Towa Kasei Kogyo Kk | マルチトールスラリーの連続的製造方法 |
JPH09132587A (ja) * | 1995-11-08 | 1997-05-20 | Towa Chem Ind Co Ltd | 結晶マルチトールの製造方法 |
EP0937733A2 (en) * | 1998-01-27 | 1999-08-25 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | A method for the continuous manufacture of anhydrous crystalline maltitol and a manufacturing apparatus therefor |
Also Published As
Publication number | Publication date |
---|---|
ATE474846T1 (de) | 2010-08-15 |
EP1553100A1 (en) | 2005-07-13 |
CN1307189C (zh) | 2007-03-28 |
EP1553100B1 (en) | 2010-07-21 |
US20050220959A1 (en) | 2005-10-06 |
CA2489912C (en) | 2011-01-11 |
EP1553100A4 (en) | 2007-09-05 |
KR20050010780A (ko) | 2005-01-28 |
CA2489912A1 (en) | 2003-12-31 |
KR100889972B1 (ko) | 2009-03-24 |
CN1662547A (zh) | 2005-08-31 |
JP4212103B2 (ja) | 2009-01-21 |
JPWO2004000861A1 (ja) | 2005-10-20 |
AU2003278644B2 (en) | 2009-01-29 |
AU2003278644A1 (en) | 2004-01-06 |
DE60333467D1 (de) | 2010-09-02 |
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