WO2003082847A1 - Derive de benzofurane - Google Patents
Derive de benzofurane Download PDFInfo
- Publication number
- WO2003082847A1 WO2003082847A1 PCT/JP2003/003807 JP0303807W WO03082847A1 WO 2003082847 A1 WO2003082847 A1 WO 2003082847A1 JP 0303807 W JP0303807 W JP 0303807W WO 03082847 A1 WO03082847 A1 WO 03082847A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- optionally substituted
- benzofuran derivative
- chain
- represented
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/508,512 US7531537B2 (en) | 2002-03-28 | 2003-03-27 | Benzofuran derivative |
NZ535267A NZ535267A (en) | 2002-03-28 | 2003-03-27 | Benzofuran derivatives as inhibitors of blood coagulation factor X |
IL16392303A IL163923A0 (en) | 2002-03-28 | 2003-03-27 | Benzofuran derivatives |
CA2479831A CA2479831C (en) | 2002-03-28 | 2003-03-27 | Benzofuran derivative |
DE60330847T DE60330847D1 (de) | 2002-03-28 | 2003-03-27 | Benzofuranderivat |
KR1020047015384A KR100702889B1 (ko) | 2002-03-28 | 2003-03-27 | 벤조푸란 유도체 |
AU2003221178A AU2003221178B2 (en) | 2002-03-28 | 2003-03-27 | Benzofuran derivative |
MXPA04009477A MXPA04009477A (es) | 2002-03-28 | 2003-03-27 | Derivados de benzofurano. |
DK03712982.2T DK1489078T3 (da) | 2002-03-28 | 2003-03-27 | Benzofuranderivat |
AT03712982T ATE454381T1 (de) | 2002-03-28 | 2003-03-27 | Benzofuranderivat |
EP03712982A EP1489078B1 (en) | 2002-03-28 | 2003-03-27 | Benzofuran derivative |
BR0308796-4A BR0308796A (pt) | 2002-03-28 | 2003-03-27 | Derivados de benzofurano |
NO20044644A NO331281B1 (no) | 2002-03-28 | 2004-10-27 | Benzofuranderivat, farmasoytisk preparat og anvendelse av benzofuranderivat for fremstilling av medikament for behandling av pasienter som lider av trombose. |
HK05102768.1A HK1069396A1 (en) | 2002-03-28 | 2005-04-02 | Benzofuran derivative |
US12/382,787 US20090209511A1 (en) | 2002-03-28 | 2009-03-24 | Benzofuran Derivatives |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002-91686 | 2002-03-28 | ||
JP2002091686 | 2002-03-28 | ||
JP2002-376158 | 2002-12-26 | ||
JP2002376158 | 2002-12-26 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/382,787 Division US20090209511A1 (en) | 2002-03-28 | 2009-03-24 | Benzofuran Derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2003082847A1 true WO2003082847A1 (fr) | 2003-10-09 |
Family
ID=28677558
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2003/003807 WO2003082847A1 (fr) | 2002-03-28 | 2003-03-27 | Derive de benzofurane |
Country Status (23)
Country | Link |
---|---|
US (2) | US7531537B2 (ja) |
EP (1) | EP1489078B1 (ja) |
KR (1) | KR100702889B1 (ja) |
CN (1) | CN100439351C (ja) |
AR (1) | AR039190A1 (ja) |
AT (1) | ATE454381T1 (ja) |
AU (1) | AU2003221178B2 (ja) |
BR (1) | BR0308796A (ja) |
CA (1) | CA2479831C (ja) |
DE (1) | DE60330847D1 (ja) |
DK (1) | DK1489078T3 (ja) |
ES (1) | ES2336905T3 (ja) |
HK (1) | HK1069396A1 (ja) |
IL (1) | IL163923A0 (ja) |
MX (1) | MXPA04009477A (ja) |
MY (1) | MY144928A (ja) |
NO (1) | NO331281B1 (ja) |
NZ (1) | NZ535267A (ja) |
PL (1) | PL372548A1 (ja) |
PT (1) | PT1489078E (ja) |
RU (1) | RU2286344C2 (ja) |
TW (1) | TWI277416B (ja) |
WO (1) | WO2003082847A1 (ja) |
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004063202A1 (ja) * | 2003-01-09 | 2004-07-29 | Tanabe Seiyaku Co., Ltd. | 縮合フラン化合物 |
WO2005030759A1 (ja) * | 2003-09-26 | 2005-04-07 | Tanabe Seiyaku Co., Ltd. | カルバモイル型ベンゾフラン誘導体 |
WO2005030706A1 (ja) * | 2003-09-26 | 2005-04-07 | Tanabe Seiyaku Co., Ltd. | アミド型カルボキサミド誘導体 |
FR2862965A1 (fr) * | 2003-11-27 | 2005-06-03 | Merck Sante Sas | Nouveaux derives de phenoxyacetamides et leur utilisation pour la preparation de diphenylamides. |
JP2006045220A (ja) * | 2004-07-08 | 2006-02-16 | Tanabe Seiyaku Co Ltd | 医薬組成物 |
EP1640373A1 (en) * | 2003-06-30 | 2006-03-29 | Tanabe Seiyaku Co., Ltd. | Process for producing 3-acylaminobenzofuran-2-carboxylic acid derivative |
JP2006298909A (ja) * | 2005-03-25 | 2006-11-02 | Tanabe Seiyaku Co Ltd | 医薬組成物 |
JP2007506762A (ja) * | 2003-09-25 | 2007-03-22 | ワイス | Pai−1の阻害剤としての置換ピロール−インドール |
US7745623B2 (en) | 2004-05-21 | 2010-06-29 | Takeda Pharmaceutical Company Limited | Cyclic amide derivative, and its production and use |
WO2010101247A1 (ja) | 2009-03-05 | 2010-09-10 | 塩野義製薬株式会社 | Npy y5受容体拮抗作用を有するシクロヘキサン誘導体 |
US8017630B2 (en) * | 2004-05-10 | 2011-09-13 | Gruenenthal Gmbh | Cyclohexylacetic acid compounds |
WO2019054427A1 (ja) | 2017-09-14 | 2019-03-21 | 第一三共株式会社 | 環状構造を有する化合物 |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1564213A4 (en) * | 2002-11-22 | 2009-05-27 | Takeda Pharmaceutical | IMIDAZOLE DERIVATIVES, PROCESS FOR THE PRODUCTION AND USE THEREOF |
US8273900B2 (en) | 2008-08-07 | 2012-09-25 | Novartis Ag | Organic compounds |
UY34295A (es) * | 2011-09-08 | 2013-04-30 | Servier Lab | Nuevo esquema de administración de la n-hidroxi -4- {2-[3- (n,ndimetilaminometil)benzofuran -2- ilcarbonilamino]etoxi}benzamida |
EP2780015B1 (en) * | 2011-11-18 | 2017-01-04 | Heptares Therapeutics Limited | Muscarinic m1 receptor agonists |
GB201617454D0 (en) | 2016-10-14 | 2016-11-30 | Heptares Therapeutics Limited | Pharmaceutical compounds |
GB201810239D0 (en) | 2018-06-22 | 2018-08-08 | Heptares Therapeutics Ltd | Pharmaceutical compounds |
GB201819960D0 (en) | 2018-12-07 | 2019-01-23 | Heptares Therapeutics Ltd | Pharmaceutical compounds |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000039118A1 (en) * | 1998-12-23 | 2000-07-06 | Eli Lilly And Company | Aromatic amides |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0937711A1 (de) | 1998-02-18 | 1999-08-25 | Roche Diagnostics GmbH | Neue Thiobenzamide, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel |
US7112594B2 (en) | 2000-08-09 | 2006-09-26 | Mitsubishi Pharma Corporation | Fused bicyclic amide compounds and medicinal use thereof |
TW200524915A (en) * | 2003-09-26 | 2005-08-01 | Tanabe Seiyaku Co | Carbamoyl-type benzofuran derivatives |
-
2003
- 2003-03-27 CN CNB038117916A patent/CN100439351C/zh not_active Expired - Fee Related
- 2003-03-27 MX MXPA04009477A patent/MXPA04009477A/es active IP Right Grant
- 2003-03-27 US US10/508,512 patent/US7531537B2/en not_active Expired - Fee Related
- 2003-03-27 KR KR1020047015384A patent/KR100702889B1/ko not_active IP Right Cessation
- 2003-03-27 RU RU2004131680/04A patent/RU2286344C2/ru not_active IP Right Cessation
- 2003-03-27 NZ NZ535267A patent/NZ535267A/xx not_active IP Right Cessation
- 2003-03-27 TW TW092106888A patent/TWI277416B/zh not_active IP Right Cessation
- 2003-03-27 EP EP03712982A patent/EP1489078B1/en not_active Expired - Lifetime
- 2003-03-27 PT PT03712982T patent/PT1489078E/pt unknown
- 2003-03-27 DK DK03712982.2T patent/DK1489078T3/da active
- 2003-03-27 BR BR0308796-4A patent/BR0308796A/pt not_active IP Right Cessation
- 2003-03-27 IL IL16392303A patent/IL163923A0/xx unknown
- 2003-03-27 CA CA2479831A patent/CA2479831C/en not_active Expired - Fee Related
- 2003-03-27 PL PL03372548A patent/PL372548A1/xx not_active Application Discontinuation
- 2003-03-27 ES ES03712982T patent/ES2336905T3/es not_active Expired - Lifetime
- 2003-03-27 DE DE60330847T patent/DE60330847D1/de not_active Expired - Lifetime
- 2003-03-27 AT AT03712982T patent/ATE454381T1/de active
- 2003-03-27 AU AU2003221178A patent/AU2003221178B2/en not_active Ceased
- 2003-03-27 WO PCT/JP2003/003807 patent/WO2003082847A1/ja active Application Filing
- 2003-03-28 AR ARP030101103A patent/AR039190A1/es unknown
- 2003-03-28 MY MYPI20031170A patent/MY144928A/en unknown
-
2004
- 2004-10-27 NO NO20044644A patent/NO331281B1/no not_active IP Right Cessation
-
2005
- 2005-04-02 HK HK05102768.1A patent/HK1069396A1/xx not_active IP Right Cessation
-
2009
- 2009-03-24 US US12/382,787 patent/US20090209511A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000039118A1 (en) * | 1998-12-23 | 2000-07-06 | Eli Lilly And Company | Aromatic amides |
Non-Patent Citations (1)
Title |
---|
VITI GIOVANNI: "Synthesis of new arylbenzofu radiozepin-6-ones", JOURNAL OF HETEROCYCLIC CHEMISTRY, vol. 27, no. 5, 1990, pages 1369 - 1375, XP002962139 * |
Cited By (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7737161B2 (en) | 2003-01-09 | 2010-06-15 | Mitsubishi Tanabe Pharma Corporation | Condensed furan compounds |
US7514449B2 (en) | 2003-01-09 | 2009-04-07 | Mitsubishi Tanabe Pharma Corporation | Fused furan compound |
WO2004063202A1 (ja) * | 2003-01-09 | 2004-07-29 | Tanabe Seiyaku Co., Ltd. | 縮合フラン化合物 |
EP1640373A1 (en) * | 2003-06-30 | 2006-03-29 | Tanabe Seiyaku Co., Ltd. | Process for producing 3-acylaminobenzofuran-2-carboxylic acid derivative |
EP1640373A4 (en) * | 2003-06-30 | 2008-07-02 | Mitsubishi Tanabe Pharma Corp | PROCESS FOR PRODUCING 3-ACYLAMINOBENZOFURAN-2-CARBOXYLIC ACID DERIVATIVE |
JP2007506762A (ja) * | 2003-09-25 | 2007-03-22 | ワイス | Pai−1の阻害剤としての置換ピロール−インドール |
US7375119B2 (en) | 2003-09-26 | 2008-05-20 | Mitsubishi Tanabe Pharma Corporation | Amide type carboxamide derivative |
WO2005030706A1 (ja) * | 2003-09-26 | 2005-04-07 | Tanabe Seiyaku Co., Ltd. | アミド型カルボキサミド誘導体 |
US7605158B2 (en) | 2003-09-26 | 2009-10-20 | Mitsubishi Tanabe Pharma Corporation | Carbamoyl-type benzofuran derivatives |
WO2005030759A1 (ja) * | 2003-09-26 | 2005-04-07 | Tanabe Seiyaku Co., Ltd. | カルバモイル型ベンゾフラン誘導体 |
WO2005051892A1 (en) * | 2003-11-27 | 2005-06-09 | Merck Patent Gmbh | Novel phenoxyacetamide derivatives and use thereof for the preparation of diphenylamines |
FR2862965A1 (fr) * | 2003-11-27 | 2005-06-03 | Merck Sante Sas | Nouveaux derives de phenoxyacetamides et leur utilisation pour la preparation de diphenylamides. |
US8017630B2 (en) * | 2004-05-10 | 2011-09-13 | Gruenenthal Gmbh | Cyclohexylacetic acid compounds |
US8697865B2 (en) | 2004-05-21 | 2014-04-15 | Takeda Pharmaceutical Company Limited | Cyclic amide derivative, and its production and use |
US7745623B2 (en) | 2004-05-21 | 2010-06-29 | Takeda Pharmaceutical Company Limited | Cyclic amide derivative, and its production and use |
JP2006045220A (ja) * | 2004-07-08 | 2006-02-16 | Tanabe Seiyaku Co Ltd | 医薬組成物 |
JP4710445B2 (ja) * | 2004-07-08 | 2011-06-29 | 田辺三菱製薬株式会社 | 医薬組成物 |
JP2006298909A (ja) * | 2005-03-25 | 2006-11-02 | Tanabe Seiyaku Co Ltd | 医薬組成物 |
WO2010101247A1 (ja) | 2009-03-05 | 2010-09-10 | 塩野義製薬株式会社 | Npy y5受容体拮抗作用を有するシクロヘキサン誘導体 |
WO2019054427A1 (ja) | 2017-09-14 | 2019-03-21 | 第一三共株式会社 | 環状構造を有する化合物 |
Also Published As
Publication number | Publication date |
---|---|
KR100702889B1 (ko) | 2007-04-04 |
CA2479831A1 (en) | 2003-10-09 |
DK1489078T3 (da) | 2010-03-15 |
NZ535267A (en) | 2006-03-31 |
DE60330847D1 (de) | 2010-02-25 |
BR0308796A (pt) | 2005-01-11 |
MXPA04009477A (es) | 2005-01-25 |
US7531537B2 (en) | 2009-05-12 |
RU2004131680A (ru) | 2005-06-27 |
ATE454381T1 (de) | 2010-01-15 |
CA2479831C (en) | 2010-06-08 |
EP1489078A4 (en) | 2006-01-04 |
NO20044644L (no) | 2004-12-16 |
NO331281B1 (no) | 2011-11-14 |
ES2336905T3 (es) | 2010-04-19 |
US20090209511A1 (en) | 2009-08-20 |
AR039190A1 (es) | 2005-02-09 |
TWI277416B (en) | 2007-04-01 |
IL163923A0 (en) | 2005-12-18 |
KR20040111442A (ko) | 2004-12-31 |
US20050282808A1 (en) | 2005-12-22 |
TW200306812A (en) | 2003-12-01 |
MY144928A (en) | 2011-11-30 |
CN100439351C (zh) | 2008-12-03 |
PT1489078E (pt) | 2010-02-24 |
AU2003221178A1 (en) | 2003-10-13 |
PL372548A1 (en) | 2005-07-25 |
EP1489078B1 (en) | 2010-01-06 |
CN1656086A (zh) | 2005-08-17 |
AU2003221178B2 (en) | 2006-06-15 |
EP1489078A1 (en) | 2004-12-22 |
RU2286344C2 (ru) | 2006-10-27 |
HK1069396A1 (en) | 2005-05-20 |
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