WO2002046194A2 - Substituted imidazopyridines - Google Patents

Substituted imidazopyridines Download PDF

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Publication number
WO2002046194A2
WO2002046194A2 PCT/US2001/046915 US0146915W WO0246194A2 WO 2002046194 A2 WO2002046194 A2 WO 2002046194A2 US 0146915 W US0146915 W US 0146915W WO 0246194 A2 WO0246194 A2 WO 0246194A2
Authority
WO
WIPO (PCT)
Prior art keywords
alkyl
aryl
compound
alkenyl
heteroaryl
Prior art date
Application number
PCT/US2001/046915
Other languages
English (en)
French (fr)
Other versions
WO2002046194A3 (en
Inventor
Kyle J. Lindstrom
Original Assignee
3M Innovative Properties Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to UA2003042937A priority Critical patent/UA74593C2/uk
Priority to IL15588501A priority patent/IL155885A0/xx
Priority to CA002431040A priority patent/CA2431040A1/en
Priority to KR10-2003-7007533A priority patent/KR20030070048A/ko
Priority to AU3954702A priority patent/AU3954702A/xx
Priority to AU2002239547A priority patent/AU2002239547B2/en
Priority to SK714-2003A priority patent/SK7142003A3/sk
Priority to HU0600592A priority patent/HUP0600592A2/hu
Priority to EP01987315A priority patent/EP1343783A2/en
Priority to JP2002547931A priority patent/JP2004525868A/ja
Application filed by 3M Innovative Properties Company filed Critical 3M Innovative Properties Company
Priority to PL01365739A priority patent/PL365739A1/xx
Priority to EEP200300273A priority patent/EE200300273A/xx
Priority to NZ526085A priority patent/NZ526085A/xx
Priority to MXPA03005013A priority patent/MXPA03005013A/es
Priority to BR0116034-6A priority patent/BR0116034A/pt
Publication of WO2002046194A2 publication Critical patent/WO2002046194A2/en
Publication of WO2002046194A3 publication Critical patent/WO2002046194A3/en
Priority to NO20032453A priority patent/NO20032453L/no
Priority to HR20030465A priority patent/HRP20030465A2/hr
Priority to HK04106187A priority patent/HK1063466A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
PCT/US2001/046915 2000-12-08 2001-12-06 Substituted imidazopyridines WO2002046194A2 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
UA2003042937A UA74593C2 (en) 2000-12-08 2001-06-12 Substituted imidazopyridines
MXPA03005013A MXPA03005013A (es) 2000-12-08 2001-12-06 Imidazopiridinas sustituidas.
KR10-2003-7007533A KR20030070048A (ko) 2000-12-08 2001-12-06 치환 이미다조피리딘
AU3954702A AU3954702A (en) 2000-12-08 2001-12-06 Substituted imidazopyridines
AU2002239547A AU2002239547B2 (en) 2000-12-08 2001-12-06 Substituted imidazopyridines
SK714-2003A SK7142003A3 (en) 2000-12-08 2001-12-06 Substituted imidazopyridines
HU0600592A HUP0600592A2 (en) 2000-12-08 2001-12-06 Substituted imidazopyridines, pharmaceutical compositions containing them and intermediates
PL01365739A PL365739A1 (en) 2000-12-08 2001-12-06 Substituted imidazopyridines
JP2002547931A JP2004525868A (ja) 2000-12-08 2001-12-06 置換イミダゾピリジン類
IL15588501A IL155885A0 (en) 2000-12-08 2001-12-06 Substituted imidazopyridines
EP01987315A EP1343783A2 (en) 2000-12-08 2001-12-06 Substituted imidazopyridines
EEP200300273A EE200300273A (et) 2000-12-08 2001-12-06 Asendatud imidasopüridiinid
NZ526085A NZ526085A (en) 2000-12-08 2001-12-06 Substituted imidazopyridines
CA002431040A CA2431040A1 (en) 2000-12-08 2001-12-06 Substituted imidazopyridines
BR0116034-6A BR0116034A (pt) 2000-12-08 2001-12-06 Imidazopiridinas substituìdas
NO20032453A NO20032453L (no) 2000-12-08 2003-05-28 Substituerte imidazopyridiner
HR20030465A HRP20030465A2 (en) 2000-12-08 2003-06-06 Substituted imidazopyridines
HK04106187A HK1063466A1 (en) 2000-12-08 2004-08-18 Substituted imidazopyridines

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25422800P 2000-12-08 2000-12-08
US60/254,228 2000-12-08

Publications (2)

Publication Number Publication Date
WO2002046194A2 true WO2002046194A2 (en) 2002-06-13
WO2002046194A3 WO2002046194A3 (en) 2003-02-06

Family

ID=22963437

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/046915 WO2002046194A2 (en) 2000-12-08 2001-12-06 Substituted imidazopyridines

Country Status (24)

Country Link
EP (1) EP1343783A2 (uk)
JP (1) JP2004525868A (uk)
KR (1) KR20030070048A (uk)
CN (1) CN1249062C (uk)
AR (1) AR035670A1 (uk)
AU (2) AU3954702A (uk)
BR (1) BR0116034A (uk)
CA (1) CA2431040A1 (uk)
CZ (1) CZ20031593A3 (uk)
EE (1) EE200300273A (uk)
HK (1) HK1063466A1 (uk)
HR (1) HRP20030465A2 (uk)
HU (1) HUP0600592A2 (uk)
IL (1) IL155885A0 (uk)
MX (1) MXPA03005013A (uk)
NO (1) NO20032453L (uk)
NZ (1) NZ526085A (uk)
PL (1) PL365739A1 (uk)
RU (1) RU2294934C2 (uk)
SK (1) SK7142003A3 (uk)
TW (1) TWI243819B (uk)
UA (1) UA74593C2 (uk)
WO (1) WO2002046194A2 (uk)
ZA (1) ZA200305238B (uk)

Cited By (45)

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US6525064B1 (en) 2000-12-08 2003-02-25 3M Innovative Properties Company Sulfonamido substituted imidazopyridines
US6534654B2 (en) 1996-06-21 2003-03-18 3M Innovative Properties Company Process for preparing imidazoquinolinamines
US6545017B1 (en) 2000-12-08 2003-04-08 3M Innovative Properties Company Urea substituted imidazopyridines
US6545016B1 (en) 2000-12-08 2003-04-08 3M Innovative Properties Company Amide substituted imidazopyridines
WO2003050119A2 (en) * 2001-12-06 2003-06-19 3M Innovative Properties Company Urea substituted imidazopyridines
US6660735B2 (en) 2000-12-08 2003-12-09 3M Innovative Properties Company Urea substituted imidazoquinoline ethers
WO2003101949A2 (en) * 2002-05-29 2003-12-11 3M Innovative Properties Company Process for imidazo[4,5-c]pyridin-4-amines
US6664265B2 (en) 2000-12-08 2003-12-16 3M Innovative Properties Company Amido ether substituted imidazoquinolines
US6667312B2 (en) 2000-12-08 2003-12-23 3M Innovative Properties Company Thioether substituted imidazoquinolines
US6677348B2 (en) 2000-12-08 2004-01-13 3M Innovative Properties Company Aryl ether substituted imidazoquinolines
US6677347B2 (en) 2000-12-08 2004-01-13 3M Innovative Properties Company Sulfonamido ether substituted imidazoquinolines
US6699878B2 (en) 1997-12-11 2004-03-02 3M Innovative Properties Company Imidazonaphthyridines
US6780873B2 (en) 1999-06-10 2004-08-24 3M Innovative Properties Company Urea substituted imidazoquinolines
US6818650B2 (en) 2002-09-26 2004-11-16 3M Innovative Properties Company 1H-imidazo dimers
US6825350B2 (en) 1999-06-10 2004-11-30 3M Innovative Properties Company Sulfonamide and sulfamide substituted imidazoquinolines and methods for the treatment of periodontal disease using these and other immune response modifiers
WO2005066172A1 (en) * 2003-12-29 2005-07-21 3M Innovative Properties Company Piperazine, [1,4]diazepane, [1,4]diazocane, and [1,5]diazocane fused imidazo ring compounds
US6943255B2 (en) 2003-06-06 2005-09-13 3M Innovative Properties Company Process for imidazo[4,5-c]pyridin-4-amines
EP1608282A2 (en) * 2003-03-13 2005-12-28 3M Innovative Properties Company Methods for diagnosing skin lesions
US7132429B2 (en) 2000-12-08 2006-11-07 3M Innovative Properties Company Sulfonamido ether substituted imidazoquinolines
US7288550B2 (en) 2000-12-08 2007-10-30 3M Innovative Properties Company Thioether substituted imidazoquinolines
US7299453B2 (en) 2001-12-20 2007-11-20 International Business Machines Corporation Testing measurements
US7393859B2 (en) 1999-06-10 2008-07-01 Coley Pharmaceutical Group, Inc. Amide substituted imidazoquinolines
US7427629B2 (en) 2002-08-15 2008-09-23 3M Innovative Properties Company Immunostimulatory compositions and methods of stimulating an immune response
JP2009509971A (ja) * 2005-09-23 2009-03-12 コーリー ファーマシューティカル グループ，インコーポレイテッド １Ｈ−イミダゾ［４，５−ｃ］ピリジンおよびその類似体のための方法
US7598382B2 (en) 2002-12-20 2009-10-06 Coley Pharmaceutical Group, Inc. Aryl substituted imidazoquinolines
US7696159B2 (en) 2003-03-25 2010-04-13 Graceway Pharmaceuticals, Llc Treatment for basal cell carcinoma
US7923560B2 (en) 2003-04-10 2011-04-12 3M Innovative Properties Company Delivery of immune response modifier compounds
US7968562B2 (en) 2001-11-29 2011-06-28 3M Innovative Properties Company Pharmaceutical formulations comprising an immune response modifier
US8110582B2 (en) 2003-03-04 2012-02-07 3M Innovative Properties Company Prophylactic treatment of UV-induced epidermal neoplasia
US8426457B2 (en) 2003-03-13 2013-04-23 Medicis Pharmaceutical Corporation Methods of improving skin quality
US8691837B2 (en) 2003-11-25 2014-04-08 3M Innovative Properties Company Substituted imidazo ring systems and methods
US8940755B2 (en) 2003-12-02 2015-01-27 3M Innovative Properties Company Therapeutic combinations and methods including IRM compounds
WO2015103990A1 (en) 2014-01-10 2015-07-16 Shanghai Birdie Biotech, Inc. Compounds and compositions for treating egfr expressing tumors
WO2016004875A1 (en) 2014-07-09 2016-01-14 Shanghai Birdie Biotech, Inc. Combination therapy compositions and methods for treating cancers
WO2016004876A1 (en) 2014-07-09 2016-01-14 Shanghai Birdie Biotech, Inc. Anti-pd-l1 combinations for treating tumors
US9248127B2 (en) 2005-02-04 2016-02-02 3M Innovative Properties Company Aqueous gel formulations containing immune response modifiers
US9920052B2 (en) 2013-12-09 2018-03-20 Ucb Biopharma Sprl Imidazopyridine derivatives as modulators of TNF activity
US10105426B2 (en) 2002-12-30 2018-10-23 Trustees Of Dartmouth College Immunostimulatory combinations
US10548988B2 (en) 2012-07-18 2020-02-04 Birdie Biopharmaceuticals, Inc. Compounds for targeted immunotherapy
EP3763742A1 (en) 2014-09-01 2021-01-13 Birdie Biopharmaceuticals Inc. Anti-pd-l1 conjugates for treating tumors
US11046781B2 (en) 2016-01-07 2021-06-29 Birdie Biopharmaceuticals, Inc. Anti-HER2 combinations for treating tumors
US11053240B2 (en) 2017-04-27 2021-07-06 Birdie Biopharmaceuticals, Inc. 2-amino-quinoline derivatives
US11136397B2 (en) 2016-01-07 2021-10-05 Birdie Pharmaceuticals, Inc. Anti-EGFR combinations for treating tumors
US11220552B2 (en) 2016-01-07 2022-01-11 Birdie Biopharmaceuticals, Inc. Anti-CD20 combinations for treating tumors
US11517567B2 (en) 2017-06-23 2022-12-06 Birdie Biopharmaceuticals, Inc. Pharmaceutical compositions

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BRPI0413558A (pt) 2003-08-12 2006-10-17 3M Innovative Properties Co compostos contendo imidazo substituìdo por hidroxilamina
US8961477B2 (en) 2003-08-25 2015-02-24 3M Innovative Properties Company Delivery of immune response modifier compounds
KR101106812B1 (ko) 2003-08-27 2012-01-19 쓰리엠 이노베이티브 프로퍼티즈 컴파니 아릴옥시 및 아릴알킬렌옥시 치환된 이미다조퀴놀린
WO2005023190A2 (en) 2003-09-05 2005-03-17 3M Innovative Properties Company Treatment for cd5+ b cell lymphoma
US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
CA2540541C (en) 2003-10-03 2012-03-27 3M Innovative Properties Company Alkoxy substituted imidazoquinolines
JP2007511527A (ja) 2003-11-14 2007-05-10 スリーエム イノベイティブ プロパティズ カンパニー オキシム置換イミダゾ環化合物
CN1906192A (zh) 2003-11-14 2007-01-31 3M创新有限公司 羟胺取代的咪唑环化合物
EP1701955A1 (en) 2003-12-29 2006-09-20 3M Innovative Properties Company Arylalkenyl and arylalkynyl substituted imidazoquinolines
WO2005066169A2 (en) 2003-12-30 2005-07-21 3M Innovative Properties Company Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
WO2005094531A2 (en) 2004-03-24 2005-10-13 3M Innovative Properties Company Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
US8017779B2 (en) 2004-06-15 2011-09-13 3M Innovative Properties Company Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
WO2006009826A1 (en) 2004-06-18 2006-01-26 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
WO2006038923A2 (en) 2004-06-18 2006-04-13 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
US7915281B2 (en) 2004-06-18 2011-03-29 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method
AU2005322898B2 (en) 2004-12-30 2011-11-24 3M Innovative Properties Company Chiral fused (1,2)imidazo(4,5-c) ring compounds
ES2392648T3 (es) 2004-12-30 2012-12-12 3M Innovative Properties Company Compuestos quirales sustituidos que contienen un núcleo 1,2-imidazo-4,5-c condensado
JP2008530113A (ja) 2005-02-11 2008-08-07 コーリー ファーマシューティカル グループ，インコーポレイテッド オキシムおよびヒドロキシラミン置換イミダゾ［４，５−ｃ］環化合物および方法
JP2008538550A (ja) 2005-04-01 2008-10-30 コーリー ファーマシューティカル グループ，インコーポレイテッド ウイルス感染および腫瘍性疾患を処置するためのサイトカイン生合成の調節因子としての１−置換ピラゾロ（３，４−ｃ）環状化合物
JP2008535832A (ja) 2005-04-01 2008-09-04 コーリー ファーマシューティカル グループ，インコーポレイテッド ピラゾロピリジン−１，４−ジアミン、およびそのアナログ
CN100344325C (zh) * 2005-10-17 2007-10-24 华南师范大学 一种治疗宫颈癌的药物及其制备方法与应用
US7906506B2 (en) 2006-07-12 2011-03-15 3M Innovative Properties Company Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods
WO2009034411A1 (en) * 2007-09-12 2009-03-19 Centre National De La Recherche Scientifique Perharidines as cdk inhibitors

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US6541485B1 (en) * 1999-06-10 2003-04-01 3M Innovative Properties Company Urea substituted imidazoquinolines
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Cited By (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6534654B2 (en) 1996-06-21 2003-03-18 3M Innovative Properties Company Process for preparing imidazoquinolinamines
US7026482B2 (en) 1996-06-21 2006-04-11 Gerster John F Process for preparing imidazoquinolinamines
US6897314B2 (en) 1996-06-21 2005-05-24 3M Innovative Properties Company Process for preparing imidazoquinolinamines
US6613902B2 (en) 1996-06-21 2003-09-02 3M Innovative Properties Company Process for preparing imidazoquinolinamines
US6624305B2 (en) 1996-06-21 2003-09-23 3M Innovative Properties Company Process for preparing imidazoquinolinamines
US6699878B2 (en) 1997-12-11 2004-03-02 3M Innovative Properties Company Imidazonaphthyridines
US7335773B2 (en) 1997-12-11 2008-02-26 Graceway Pharmaceuticals, Llc Intermediates for imidazonaphthyridines
US7678918B2 (en) 1997-12-11 2010-03-16 3M Innovative Properties Company Intermediates for imidazonaphthyridines
US7393859B2 (en) 1999-06-10 2008-07-01 Coley Pharmaceutical Group, Inc. Amide substituted imidazoquinolines
US6825350B2 (en) 1999-06-10 2004-11-30 3M Innovative Properties Company Sulfonamide and sulfamide substituted imidazoquinolines and methods for the treatment of periodontal disease using these and other immune response modifiers
US6780873B2 (en) 1999-06-10 2004-08-24 3M Innovative Properties Company Urea substituted imidazoquinolines
US6720334B2 (en) 2000-12-08 2004-04-13 3M Innovative Properties Company Urea substituted imidazopyridines
US6878719B2 (en) 2000-12-08 2005-04-12 3M Innovative Properties Company Sulfonamido substituted imidazopyridines
US6667312B2 (en) 2000-12-08 2003-12-23 3M Innovative Properties Company Thioether substituted imidazoquinolines
US6677348B2 (en) 2000-12-08 2004-01-13 3M Innovative Properties Company Aryl ether substituted imidazoquinolines
US6677347B2 (en) 2000-12-08 2004-01-13 3M Innovative Properties Company Sulfonamido ether substituted imidazoquinolines
US6696465B2 (en) 2000-12-08 2004-02-24 3M Innovative Properties Company Sulfonamido substituted imidazopyridines
US7214675B2 (en) 2000-12-08 2007-05-08 3M Innovative Properties Company Urea substituted imidazoquinoline ethers
US6716988B2 (en) 2000-12-08 2004-04-06 3M Innovative Properties Company Urea substituted imidazopyridines
US6720422B2 (en) 2000-12-08 2004-04-13 3M Innovative Properties Company Amide substituted imidazopyridines
US7276515B2 (en) 2000-12-08 2007-10-02 Coley Pharmaceutical Group, Inc. Thioether substituted imidazoquinolines
US6720333B2 (en) 2000-12-08 2004-04-13 3M Innovative Properties Company Amide substituted imidazopyridines
US6660735B2 (en) 2000-12-08 2003-12-09 3M Innovative Properties Company Urea substituted imidazoquinoline ethers
US7132429B2 (en) 2000-12-08 2006-11-07 3M Innovative Properties Company Sulfonamido ether substituted imidazoquinolines
US7115622B2 (en) 2000-12-08 2006-10-03 3M Innovative Properties Company Amido ether substituted imidazoquinolines
US7288550B2 (en) 2000-12-08 2007-10-30 3M Innovative Properties Company Thioether substituted imidazoquinolines
US6664265B2 (en) 2000-12-08 2003-12-16 3M Innovative Properties Company Amido ether substituted imidazoquinolines
US7098221B2 (en) 2000-12-08 2006-08-29 3M Innovative Properties Company Amide substituted imidazopyridines
US6903113B2 (en) 2000-12-08 2005-06-07 3M Innovative Properties Company Urea substituted imidazopyridines
US6545017B1 (en) 2000-12-08 2003-04-08 3M Innovative Properties Company Urea substituted imidazopyridines
US6525064B1 (en) 2000-12-08 2003-02-25 3M Innovative Properties Company Sulfonamido substituted imidazopyridines
US6545016B1 (en) 2000-12-08 2003-04-08 3M Innovative Properties Company Amide substituted imidazopyridines
US6969722B2 (en) 2000-12-08 2005-11-29 3M Innovative Properties Company Amide substituted imidazopyridines
US7968562B2 (en) 2001-11-29 2011-06-28 3M Innovative Properties Company Pharmaceutical formulations comprising an immune response modifier
WO2003050119A2 (en) * 2001-12-06 2003-06-19 3M Innovative Properties Company Urea substituted imidazopyridines
WO2003050117A1 (en) * 2001-12-06 2003-06-19 3M Innovative Properties Company Sulfonamido substituted imidazopyridines
WO2003050118A1 (en) * 2001-12-06 2003-06-19 3M Innovative Properties Company Amide substituted imidazopyridines
WO2003050119A3 (en) * 2001-12-06 2003-07-10 3M Innovative Properties Co Urea substituted imidazopyridines
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