WO1997040008A1 - Procede de preparation de derives pyrrolidiniques - Google Patents

Procede de preparation de derives pyrrolidiniques Download PDF

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Publication number
WO1997040008A1
WO1997040008A1 PCT/JP1997/001373 JP9701373W WO9740008A1 WO 1997040008 A1 WO1997040008 A1 WO 1997040008A1 JP 9701373 W JP9701373 W JP 9701373W WO 9740008 A1 WO9740008 A1 WO 9740008A1
Authority
WO
WIPO (PCT)
Prior art keywords
acid
group
general formula
salt
diphenylmethyl
Prior art date
Application number
PCT/JP1997/001373
Other languages
English (en)
French (fr)
Japanese (ja)
Inventor
Natsuki Mori
Noritaka Yoshida
Takeshi Furuta
Kazunori Kan
Original Assignee
Kaneka Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaneka Corporation filed Critical Kaneka Corporation
Priority to US09/171,996 priority Critical patent/US6005119A/en
Priority to DE69715402T priority patent/DE69715402T2/de
Priority to EP97917456A priority patent/EP0900787B1/de
Publication of WO1997040008A1 publication Critical patent/WO1997040008A1/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PCT/JP1997/001373 1996-04-22 1997-04-22 Procede de preparation de derives pyrrolidiniques WO1997040008A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US09/171,996 US6005119A (en) 1996-04-22 1997-04-22 Process for preparing pyrrolidine derivatives
DE69715402T DE69715402T2 (de) 1996-04-22 1997-04-22 Verfahren zur herstellung von pyrrolidin-derivaten
EP97917456A EP0900787B1 (de) 1996-04-22 1997-04-22 Verfahren zur herstellung von pyrrolidin-derivaten

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP8/126361 1996-04-22
JP12636196 1996-04-22
JP01463997A JP4057088B2 (ja) 1996-04-22 1997-01-09 ピロリジン誘導体の製造方法
JP9/14639 1997-01-09

Publications (1)

Publication Number Publication Date
WO1997040008A1 true WO1997040008A1 (fr) 1997-10-30

Family

ID=26350627

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP1997/001373 WO1997040008A1 (fr) 1996-04-22 1997-04-22 Procede de preparation de derives pyrrolidiniques

Country Status (6)

Country Link
US (1) US6005119A (de)
EP (1) EP0900787B1 (de)
JP (1) JP4057088B2 (de)
DE (1) DE69715402T2 (de)
ES (1) ES2183160T3 (de)
WO (1) WO1997040008A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007011162A1 (en) * 2005-07-20 2007-01-25 Chiroad Incorporate Synthetic method of optically pure (s)-3-hydroxypyrrolidine

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100395779B1 (ko) * 2001-05-25 2003-08-21 한국화학연구원 임의적으로 베타-위치가 치환된 알파-아릴알킬기의 제거를통해 3급 아미드 화합물로부터 2급 아미드 화합물을제조하는 방법
CN101983187A (zh) 2008-04-02 2011-03-02 株式会社钟化 (s)-3-(1-氰基-1，1-二苯基甲基)吡咯烷的制备方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61100563A (ja) * 1984-10-19 1986-05-19 エイ・エツチ・ロビンス・カンパニー・インコーポレーテツド １‐［（アミノアルキルおよびアミノアルキルアミノ）カルボニルおよびチオカルボニル］‐α，α‐ジアリールピロリジン、ピペリジンおよびホモピペリジンアセトアミドおよびアセトニトリル
JPS62169763A (ja) * 1986-01-17 1987-07-25 エイ・エイチ・ロビンス・カンパニー・インコーポレーテッド 心血管薬、抗ヒスタミン薬および分泌抑制薬としてのｎ−置換−アリ−ルアルキル−および−アリ−ルアルキレン−アミノ複素環化合物
JPS6341453A (ja) * 1986-08-08 1988-02-22 Tokyo Kasei Kogyo Kk ３−（アシルアミノ）ピロリジン又はその塩の製造法
JPH02218664A (ja) * 1989-02-17 1990-08-31 Tokyo Kasei Kogyo Kk 光学活性な１ｈ−３−アミノピロリジン化合物の製造法
JPH03176463A (ja) * 1989-12-02 1991-07-31 Kanegafuchi Chem Ind Co Ltd ピロリジノール誘導体およびその製法
JPH0495067A (ja) * 1990-08-09 1992-03-27 Fujisawa Pharmaceut Co Ltd ピロリジン化合物の製造法
JPH0558995A (ja) * 1991-09-04 1993-03-09 Shionogi & Co Ltd ピロリジン誘導体の製造法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208423A (en) * 1978-11-24 1980-06-17 Syntex Inc. Anticholinergic bronchodilators
US4810703A (en) * 1984-10-19 1989-03-07 A. H. Robins Company, Incorporated 1-((aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-alpha, alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles
DE3501496A1 (de) * 1985-01-18 1986-07-24 Behringwerke Ag, 3550 Marburg Verfahren zur bestimmung der aktivitaet des komplementsystems des blutes
US4851418A (en) * 1987-08-21 1989-07-25 Warner-Lambert Company Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent
FR2687146B1 (fr) * 1992-02-12 1994-04-01 Adir Cie Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61100563A (ja) * 1984-10-19 1986-05-19 エイ・エツチ・ロビンス・カンパニー・インコーポレーテツド １‐［（アミノアルキルおよびアミノアルキルアミノ）カルボニルおよびチオカルボニル］‐α，α‐ジアリールピロリジン、ピペリジンおよびホモピペリジンアセトアミドおよびアセトニトリル
JPS62169763A (ja) * 1986-01-17 1987-07-25 エイ・エイチ・ロビンス・カンパニー・インコーポレーテッド 心血管薬、抗ヒスタミン薬および分泌抑制薬としてのｎ−置換−アリ−ルアルキル−および−アリ−ルアルキレン−アミノ複素環化合物
JPS6341453A (ja) * 1986-08-08 1988-02-22 Tokyo Kasei Kogyo Kk ３−（アシルアミノ）ピロリジン又はその塩の製造法
JPH02218664A (ja) * 1989-02-17 1990-08-31 Tokyo Kasei Kogyo Kk 光学活性な１ｈ−３−アミノピロリジン化合物の製造法
JPH03176463A (ja) * 1989-12-02 1991-07-31 Kanegafuchi Chem Ind Co Ltd ピロリジノール誘導体およびその製法
JPH0495067A (ja) * 1990-08-09 1992-03-27 Fujisawa Pharmaceut Co Ltd ピロリジン化合物の製造法
JPH0558995A (ja) * 1991-09-04 1993-03-09 Shionogi & Co Ltd ピロリジン誘導体の製造法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP0900787A4 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007011162A1 (en) * 2005-07-20 2007-01-25 Chiroad Incorporate Synthetic method of optically pure (s)-3-hydroxypyrrolidine
US7652152B2 (en) 2005-07-20 2010-01-26 Chiroad Incorporate Synthetic method of optically pure (S)-3-hydroxypyrrolidine

Also Published As

Publication number Publication date
JP4057088B2 (ja) 2008-03-05
EP0900787A4 (de) 1999-08-11
EP0900787B1 (de) 2002-09-11
US6005119A (en) 1999-12-21
JPH107652A (ja) 1998-01-13
DE69715402T2 (de) 2003-08-07
ES2183160T3 (es) 2003-03-16
DE69715402D1 (de) 2002-10-17
EP0900787A1 (de) 1999-03-10

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