WO1997015549A1 - COMPOSES DE PHENYLETHANOLAMINE UTILES EN TANT QUE β3 AGONISTES, LEURS PROCEDE ET INTERMEDIAIRES DE PRODUCTION - Google Patents
COMPOSES DE PHENYLETHANOLAMINE UTILES EN TANT QUE β3 AGONISTES, LEURS PROCEDE ET INTERMEDIAIRES DE PRODUCTION Download PDFInfo
- Publication number
- WO1997015549A1 WO1997015549A1 PCT/JP1996/003097 JP9603097W WO9715549A1 WO 1997015549 A1 WO1997015549 A1 WO 1997015549A1 JP 9603097 W JP9603097 W JP 9603097W WO 9715549 A1 WO9715549 A1 WO 9715549A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- same
- lower alkoxy
- substituted
- agonist
- intermediates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/24—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/36—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-1998-0703029A KR100483635B1 (ko) | 1995-10-26 | 1996-10-24 | β3작동약으로서유용한페닐에탄올아민화합물,그의제법및그의제조에서의중간체 |
AU73358/96A AU715216B2 (en) | 1995-10-26 | 1996-10-24 | Phenylethanolamine compounds useful as beta3 agonist, process for producing the same, and intermediates in the production of the same |
EP96935424A EP0940387B1 (en) | 1995-10-26 | 1996-10-24 | Phenylethanolamine compounds useful as beta3 agonist, process for producing the same, and intermediates in the production of the same |
AT96935424T ATE239694T1 (de) | 1995-10-26 | 1996-10-24 | Phenylethanolamin-verbindungen und ihre anwendung als beta3 agonisten, verfahren zu ihrer herstellung und zwischenprodukte ihrer herstellung |
US09/065,077 US6069176A (en) | 1995-10-26 | 1996-10-24 | Phenylethanolamine compounds useful as β 3 agonists, process for producing the same, and intermediates in the production of the same |
JP51647697A JP3926390B2 (ja) | 1995-10-26 | 1996-10-24 | β3作業薬として有用なフェニルエタノールアミン化合物、その製法およびその製造における中間体 |
CA002235840A CA2235840C (en) | 1995-10-26 | 1996-10-24 | Phenylethanolamine compounds useful as .beta.3 agonist, process for producing the same, and intermediates in the production of the same |
DE69628051T DE69628051T2 (de) | 1995-10-26 | 1996-10-24 | Phenylethanolamin-verbindungen und ihre anwendung als beta3 agonisten, verfahren zu ihrer herstellung und zwischenprodukte ihrer herstellung |
NO981858A NO981858L (no) | 1995-10-26 | 1998-04-24 | Fenyletanolamin-forbindelser anvendelige som <beta>3 agonist, fremgangsmÕte for fremstilling av disse og mellomprodukter i fremstilling av dem |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP27855495 | 1995-10-26 | ||
JP7/278554 | 1995-10-26 | ||
JP24962296 | 1996-09-20 | ||
JP8/249622 | 1996-09-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1997015549A1 true WO1997015549A1 (fr) | 1997-05-01 |
Family
ID=26539396
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP1996/003097 WO1997015549A1 (fr) | 1995-10-26 | 1996-10-24 | COMPOSES DE PHENYLETHANOLAMINE UTILES EN TANT QUE β3 AGONISTES, LEURS PROCEDE ET INTERMEDIAIRES DE PRODUCTION |
Country Status (12)
Country | Link |
---|---|
US (1) | US6069176A (ja) |
EP (1) | EP0940387B1 (ja) |
JP (1) | JP3926390B2 (ja) |
KR (1) | KR100483635B1 (ja) |
AT (1) | ATE239694T1 (ja) |
AU (1) | AU715216B2 (ja) |
CZ (1) | CZ126598A3 (ja) |
DE (1) | DE69628051T2 (ja) |
ES (1) | ES2193266T3 (ja) |
HU (1) | HUP9802318A3 (ja) |
NO (1) | NO981858L (ja) |
WO (1) | WO1997015549A1 (ja) |
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998024754A1 (fr) * | 1996-12-04 | 1998-06-11 | Kureha Kagaku Kogyo Kabushiki Kaisha | Derives de la cyclopentyleamine, leur procede de preparation et bactericides |
EP0982026A2 (en) * | 1998-08-18 | 2000-03-01 | F. Hoffmann-La Roche Ag | Use of aryl-cyclohexylamine derivatives in the manufacture of NMDA receptor blockers |
US6184236B1 (en) | 1998-08-18 | 2001-02-06 | Hoffmann-La Roche Inc. | Method of treating a neurodegenerative disease by administering an aryl-cyclohexylamine derivative |
EP0958835A4 (en) * | 1996-08-19 | 2001-04-18 | Kissei Pharmaceutical | THERAPEUTIC OR PREVENTIVE REMEDY AGAINST INCONTINENCE OR FREQUENT URINARY ELIMINATION |
WO2002006232A1 (en) * | 2000-07-17 | 2002-01-24 | Wyeth | Cyclic amine phenyl beta-3 adrenergic receptor agonists |
EP1382333A3 (en) * | 1998-04-06 | 2004-02-04 | Fujisawa Pharmaceutical Co., Ltd. | Use of beta 3 adrenergic receptor agonists in the treatment of dysuria |
US6828460B2 (en) | 1999-03-22 | 2004-12-07 | Pfizer Inc. | Resorcinol derivatives |
WO2006043577A1 (ja) * | 2004-10-20 | 2006-04-27 | Mitsubishi Pharma Corporation | フェニルエタノールアミン化合物の製造方法及びその中間体 |
WO2007083640A1 (ja) * | 2006-01-18 | 2007-07-26 | Kyorin Pharmaceutical Co., Ltd. | 頻尿及び尿失禁の予防又は治療剤 |
JP2008515962A (ja) * | 2004-10-12 | 2008-05-15 | グレンマーク・ファーマシューティカルズ・エスエー | 新規なジペプチジルペプチダーゼiv阻害剤、それらを含む医薬品組成物、およびそれらを調製するためのプロセス |
JP2013531662A (ja) * | 2010-06-30 | 2013-08-08 | レオ ファーマ アクティーゼルスカブ | カルシウム模倣化合物の新規多形 |
JP2013531661A (ja) * | 2010-06-30 | 2013-08-08 | レオ ファーマ アクティーゼルスカブ | カルシウム模倣化合物の新規多形 |
WO2014033343A1 (es) | 2012-08-29 | 2014-03-06 | Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii (Cnic) | Agonistas de receptores beta-3 adrenérgicos para el tratamiento de hipertensión pulmonar |
US8835474B2 (en) | 2002-11-07 | 2014-09-16 | Astellas Pharma Inc. | Remedy for overactive bladder comprising acetic acid anilide derivative as the active ingredient |
JP2016047815A (ja) * | 2014-08-25 | 2016-04-07 | 住友化学株式会社 | 塩、酸発生剤、レジスト組成物及びレジストパターンの製造方法 |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1258253A1 (en) * | 2000-01-28 | 2002-11-20 | Asahi Kasei Kabushiki Kaisha | Novel remedies with the use of beta3 agonist |
MXPA02009659A (es) * | 2000-04-26 | 2003-03-10 | Warner Lambert Co | Derivado de ciclohexilamina como subtipo de los antagonistas del receptor selectivo nmda. |
EP1296934A1 (en) | 2000-06-01 | 2003-04-02 | Warner-Lambert Company | Cyclohexylamine derivatives as subtype selective nmda receptor antagonists |
CA2407164A1 (en) * | 2000-06-06 | 2001-12-13 | Warner-Lambert Company | Bicyclic cyclohexylamines and their use as nmda receptor antagonists |
US6451814B1 (en) | 2000-07-17 | 2002-09-17 | Wyeth | Heterocyclic β-3 adrenergic receptor agonists |
US6514991B2 (en) * | 2000-07-17 | 2003-02-04 | Wyeth | Phenyl-oxo-tetrahydroquinolin-3-yl beta-3 adrenergic receptor agonists |
US6506901B2 (en) | 2000-07-17 | 2003-01-14 | Wyeth | Substituted 2-(S)-hydroxy-3-(piperidin-4-yl-methylamino)-propyl ethers and substituted 2-aryl-2-(R)-hydroxy-1-(piperidin-4-yl-methyl)-ethylamine β-3 adrenergic receptor agonists |
US6537994B2 (en) | 2000-07-17 | 2003-03-25 | Wyeth | Heterocyclic β3 adrenergic receptor agonists |
US6458817B1 (en) | 2000-07-17 | 2002-10-01 | Wyeth | Substituted arylsulfides, arylsulfoxides and arylsulfones as beta-3 adrenergic receptor agonists |
US6410734B1 (en) | 2000-07-17 | 2002-06-25 | Wyeth | 2-substituted thiazolidinones as beta-3 adrenergic receptor agonists |
US6395762B1 (en) | 2000-07-17 | 2002-05-28 | American Home Products Corporation | Phenyl amino squarate and thiadiazole dioxide beta-3 adrenergic receptor agonists |
US6465501B2 (en) | 2000-07-17 | 2002-10-15 | Wyeth | Azolidines as β3 adrenergic receptor agonists |
US6509358B2 (en) | 2000-07-17 | 2003-01-21 | Wyeth | Piperidino-phenyl amino squarate and thiadiazole dioxide beta-3 adrenergic receptor agonists |
US6498170B2 (en) * | 2000-07-17 | 2002-12-24 | Wyeth | Cyclamine sulfonamides as β-3 adrenergic receptor agonists |
US6444685B1 (en) | 2000-07-17 | 2002-09-03 | Wyeth | N-(4-sulfonylaryl)Cyclylamine 2-hydroxyethylamines as beta-3 adrenergic receptor agonists |
US20040018959A1 (en) * | 2002-05-02 | 2004-01-29 | Randall S. Hickle | System and methods of lipid removal from the body |
GB0217211D0 (en) * | 2002-07-24 | 2002-09-04 | Syngenta Participations Ag | Organic compounds |
EP1424079A1 (en) * | 2002-11-27 | 2004-06-02 | Boehringer Ingelheim International GmbH | Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine |
SI1599468T1 (sl) * | 2003-01-14 | 2008-02-29 | Arena Pharm Inc | 1,2,3-trisubstituirani arilni in heteroarilni derivati kot modulatorji metabolizma ter profilaksa in zdravljenje motenj v zvezi z njim, kot diabetesain hiperglikemije |
JP2006516572A (ja) * | 2003-01-14 | 2006-07-06 | アリーナ ファーマシューティカルズ, インコーポレイテッド | 代謝モジュレーターとしての1,2,3−トリ置換アリール誘導体および1,2,3−トリ置換ヘテロアリール誘導体ならびにこれらの誘導体に関連する糖尿病および高血糖のような障害の予防および処置 |
AR045047A1 (es) | 2003-07-11 | 2005-10-12 | Arena Pharm Inc | Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos |
MXPA06004625A (es) * | 2003-11-03 | 2006-06-27 | Boehringer Ingelheim Int | Composicion famaceutica que contiene un agonista de un adrenoceptor beta-3 y un antagonista alfa y/o un inhibidor de la 5-alfa-reductasa. |
US20050250944A1 (en) * | 2004-05-04 | 2005-11-10 | Jian Chen | Synthesis and uses of synephrine derivatives |
DOP2006000010A (es) | 2005-01-10 | 2006-07-31 | Arena Pharm Inc | Procedimiento para preparar eteres aromáticos |
MY148521A (en) | 2005-01-10 | 2013-04-30 | Arena Pharm Inc | Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto |
US20080064758A1 (en) * | 2006-08-23 | 2008-03-13 | Medicinova, Inc. | Method of treatment or prophylaxis of depression |
KR100821567B1 (ko) | 2006-11-01 | 2008-04-15 | 한국화학연구원 | 광학 활성 2-설포닐옥시-1-페닐에탄올 유도체의 제조방법 |
WO2008073623A2 (en) * | 2006-11-02 | 2008-06-19 | Arete Therapeutics, Inc. | Soluble epoxide hydrolase inhibitors |
US8217027B2 (en) * | 2006-12-21 | 2012-07-10 | Abbott Laboratories | Sphingosine-1-phosphate receptor agonist and antagonist compounds |
JP5420534B2 (ja) * | 2007-05-31 | 2014-02-19 | サノビオン ファーマシューティカルズ インク | モノアミン再取り込み阻害薬としてのフェニル置換シクロアルキルアミン |
MX2010005631A (es) * | 2007-11-23 | 2010-06-02 | Leo Pharma As | Nuevos compuestos de hidrocarburo ciclicos para el tratamiento de enfermedades. |
US9907767B2 (en) | 2010-08-03 | 2018-03-06 | Velicept Therapeutics, Inc. | Pharmaceutical compositions and the treatment of overactive bladder |
US9522129B2 (en) | 2010-08-03 | 2016-12-20 | Velicept Therapeutics, Inc. | Pharmaceutical Combination |
JP2013535486A (ja) | 2010-08-03 | 2013-09-12 | アルセレックス,インコーポレイテッド | 過活動膀胱を治療するためのβ−3アドレナリン受容体アゴニストおよびムスカリン受容体アンタゴニストの組み合わせ |
CA2812061A1 (en) | 2010-09-22 | 2012-03-29 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
US9956194B2 (en) | 2014-12-03 | 2018-05-01 | Velicept Therapeutics, Inc. | Compositions and methods of using modified release solabegron for lower urinary tract symptoms |
EP3242666A1 (en) | 2015-01-06 | 2017-11-15 | Arena Pharmaceuticals, Inc. | Methods of treating conditions related to the s1p1 receptor |
CN108349891B (zh) | 2015-06-22 | 2022-04-05 | 艾尼纳制药公司 | 用于s1p1受体相关病症的化合物的结晶l-精氨酸盐 |
DK3365321T3 (da) | 2015-10-23 | 2024-01-15 | B3Ar Therapeutics Inc | Solabegron-zwitterion og anvendelser deraf |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3803232A (en) * | 1970-09-30 | 1974-04-09 | Ciba Geigy Corp | Arylcarboxamidines |
JPS4940226B1 (ja) * | 1970-05-02 | 1974-10-31 | ||
US4350685A (en) * | 1981-02-06 | 1982-09-21 | Smithkline Corporation | Antiallergic imidodisulfamides |
JPS62198639A (ja) * | 1986-02-26 | 1987-09-02 | Takasago Corp | α−アリ−ルカルボニル誘導体の製造法 |
US4755505A (en) * | 1987-08-18 | 1988-07-05 | American Home Products Corporation | 1-[2-(dialkylamino)alkyl]-4,5-dihydro-4-(aryl)-1-benzazocine-2,6(1H,3H)-diones as anti-arrhythmic agents |
JPH01135739A (ja) * | 1987-11-20 | 1989-05-29 | Mitsui Toatsu Chem Inc | 2−(4−ヒドロキシフェニル)−シクロヘキサノンの製造方法 |
JPH04169595A (ja) * | 1990-11-01 | 1992-06-17 | Daicel Chem Ind Ltd | 分離剤 |
JPH04211636A (ja) * | 1990-03-06 | 1992-08-03 | Basf Ag | 4−(4−第三ブチルフェニル)シクロヘキシルアミンおよびその4級アンモニウム塩、および該化合物を含有する殺菌剤 |
JPH0665107A (ja) * | 1991-10-28 | 1994-03-08 | Snow Brand Milk Prod Co Ltd | 含窒素化合物の水素化還元方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS517617B2 (ja) * | 1972-08-25 | 1976-03-09 | ||
FR2643076B1 (fr) * | 1989-02-14 | 1991-06-21 | Midy Spa | Carboxyalkyl-ethers de la 2-amino-7-hydroxytetraline |
GB9107827D0 (en) * | 1991-04-12 | 1991-05-29 | Fujisawa Pharmaceutical Co | New ethanolamine derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same |
DE4210569A1 (de) * | 1992-03-31 | 1993-10-07 | Hoechst Ag | Verwendung von substituierten µ-Hydroxyethylaminen als fungizide Wirkstoffe |
-
1996
- 1996-10-24 AT AT96935424T patent/ATE239694T1/de not_active IP Right Cessation
- 1996-10-24 KR KR10-1998-0703029A patent/KR100483635B1/ko not_active IP Right Cessation
- 1996-10-24 DE DE69628051T patent/DE69628051T2/de not_active Expired - Lifetime
- 1996-10-24 EP EP96935424A patent/EP0940387B1/en not_active Expired - Lifetime
- 1996-10-24 WO PCT/JP1996/003097 patent/WO1997015549A1/ja active IP Right Grant
- 1996-10-24 US US09/065,077 patent/US6069176A/en not_active Expired - Lifetime
- 1996-10-24 ES ES96935424T patent/ES2193266T3/es not_active Expired - Lifetime
- 1996-10-24 JP JP51647697A patent/JP3926390B2/ja not_active Expired - Fee Related
- 1996-10-24 AU AU73358/96A patent/AU715216B2/en not_active Ceased
- 1996-10-24 HU HU9802318A patent/HUP9802318A3/hu unknown
- 1996-10-24 CZ CZ981265A patent/CZ126598A3/cs unknown
-
1998
- 1998-04-24 NO NO981858A patent/NO981858L/no not_active Application Discontinuation
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4940226B1 (ja) * | 1970-05-02 | 1974-10-31 | ||
US3803232A (en) * | 1970-09-30 | 1974-04-09 | Ciba Geigy Corp | Arylcarboxamidines |
US4350685A (en) * | 1981-02-06 | 1982-09-21 | Smithkline Corporation | Antiallergic imidodisulfamides |
JPS62198639A (ja) * | 1986-02-26 | 1987-09-02 | Takasago Corp | α−アリ−ルカルボニル誘導体の製造法 |
US4755505A (en) * | 1987-08-18 | 1988-07-05 | American Home Products Corporation | 1-[2-(dialkylamino)alkyl]-4,5-dihydro-4-(aryl)-1-benzazocine-2,6(1H,3H)-diones as anti-arrhythmic agents |
JPH01135739A (ja) * | 1987-11-20 | 1989-05-29 | Mitsui Toatsu Chem Inc | 2−(4−ヒドロキシフェニル)−シクロヘキサノンの製造方法 |
JPH04211636A (ja) * | 1990-03-06 | 1992-08-03 | Basf Ag | 4−(4−第三ブチルフェニル)シクロヘキシルアミンおよびその4級アンモニウム塩、および該化合物を含有する殺菌剤 |
JPH04169595A (ja) * | 1990-11-01 | 1992-06-17 | Daicel Chem Ind Ltd | 分離剤 |
JPH0665107A (ja) * | 1991-10-28 | 1994-03-08 | Snow Brand Milk Prod Co Ltd | 含窒素化合物の水素化還元方法 |
Non-Patent Citations (1)
Title |
---|
CHEMICAL ABSTRACTS, 1980, 93:26036. * |
Cited By (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0958835A4 (en) * | 1996-08-19 | 2001-04-18 | Kissei Pharmaceutical | THERAPEUTIC OR PREVENTIVE REMEDY AGAINST INCONTINENCE OR FREQUENT URINARY ELIMINATION |
WO1998024754A1 (fr) * | 1996-12-04 | 1998-06-11 | Kureha Kagaku Kogyo Kabushiki Kaisha | Derives de la cyclopentyleamine, leur procede de preparation et bactericides |
EP1382333A3 (en) * | 1998-04-06 | 2004-02-04 | Fujisawa Pharmaceutical Co., Ltd. | Use of beta 3 adrenergic receptor agonists in the treatment of dysuria |
US6184236B1 (en) | 1998-08-18 | 2001-02-06 | Hoffmann-La Roche Inc. | Method of treating a neurodegenerative disease by administering an aryl-cyclohexylamine derivative |
EP0982026A3 (en) * | 1998-08-18 | 2001-06-13 | F. Hoffmann-La Roche Ag | Use of aryl-cyclohexylamine derivatives in the manufacture of NMDA receptor blockers |
EP0982026A2 (en) * | 1998-08-18 | 2000-03-01 | F. Hoffmann-La Roche Ag | Use of aryl-cyclohexylamine derivatives in the manufacture of NMDA receptor blockers |
US6828460B2 (en) | 1999-03-22 | 2004-12-07 | Pfizer Inc. | Resorcinol derivatives |
US6933319B2 (en) | 1999-03-22 | 2005-08-23 | Pfizer Inc. | Resorcinol derivatives |
WO2002006232A1 (en) * | 2000-07-17 | 2002-01-24 | Wyeth | Cyclic amine phenyl beta-3 adrenergic receptor agonists |
US8835474B2 (en) | 2002-11-07 | 2014-09-16 | Astellas Pharma Inc. | Remedy for overactive bladder comprising acetic acid anilide derivative as the active ingredient |
JP2008515962A (ja) * | 2004-10-12 | 2008-05-15 | グレンマーク・ファーマシューティカルズ・エスエー | 新規なジペプチジルペプチダーゼiv阻害剤、それらを含む医薬品組成物、およびそれらを調製するためのプロセス |
WO2006043577A1 (ja) * | 2004-10-20 | 2006-04-27 | Mitsubishi Pharma Corporation | フェニルエタノールアミン化合物の製造方法及びその中間体 |
JPWO2006043577A1 (ja) * | 2004-10-20 | 2008-05-22 | 田辺三菱製薬株式会社 | フェニルエタノールアミン化合物の製造方法及びその中間体 |
US7544841B2 (en) | 2004-10-20 | 2009-06-09 | Mitsubishi Tanabe Pharma Corporation | Production method of phenylethanolamine compound, and its intermediate |
JP4889501B2 (ja) * | 2004-10-20 | 2012-03-07 | 田辺三菱製薬株式会社 | フェニルエタノールアミン化合物の製造方法及びその中間体 |
WO2007083640A1 (ja) * | 2006-01-18 | 2007-07-26 | Kyorin Pharmaceutical Co., Ltd. | 頻尿及び尿失禁の予防又は治療剤 |
JP2013531661A (ja) * | 2010-06-30 | 2013-08-08 | レオ ファーマ アクティーゼルスカブ | カルシウム模倣化合物の新規多形 |
JP2013531662A (ja) * | 2010-06-30 | 2013-08-08 | レオ ファーマ アクティーゼルスカブ | カルシウム模倣化合物の新規多形 |
WO2014033343A1 (es) | 2012-08-29 | 2014-03-06 | Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii (Cnic) | Agonistas de receptores beta-3 adrenérgicos para el tratamiento de hipertensión pulmonar |
JP2016047815A (ja) * | 2014-08-25 | 2016-04-07 | 住友化学株式会社 | 塩、酸発生剤、レジスト組成物及びレジストパターンの製造方法 |
Also Published As
Publication number | Publication date |
---|---|
ES2193266T3 (es) | 2003-11-01 |
AU7335896A (en) | 1997-05-15 |
EP0940387B1 (en) | 2003-05-07 |
NO981858D0 (no) | 1998-04-24 |
KR100483635B1 (ko) | 2005-12-21 |
KR19990067089A (ko) | 1999-08-16 |
NO981858L (no) | 1998-06-24 |
AU715216B2 (en) | 2000-01-20 |
ATE239694T1 (de) | 2003-05-15 |
EP0940387A1 (en) | 1999-09-08 |
EP0940387A4 (en) | 2000-07-05 |
HUP9802318A2 (hu) | 1999-08-30 |
DE69628051T2 (de) | 2004-02-26 |
DE69628051D1 (de) | 2003-06-12 |
CZ126598A3 (cs) | 1998-09-16 |
HUP9802318A3 (en) | 2001-04-28 |
US6069176A (en) | 2000-05-30 |
JP3926390B2 (ja) | 2007-06-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO1997015549A1 (fr) | COMPOSES DE PHENYLETHANOLAMINE UTILES EN TANT QUE β3 AGONISTES, LEURS PROCEDE ET INTERMEDIAIRES DE PRODUCTION | |
UA35564C2 (uk) | Поліциклічні аміновмісні сполуки, що є антагоністами рецепторів нейрокінінів, їх фармацевтично прийнятні енантіомери, солі, n-оксиди і продукти кватернізації, спосіб їх отримання, проміжні сполуки і фармацевтична композиція | |
HK1089444A1 (en) | Dihydropteridinones, method for the production and use thereof in the form of drugs | |
WO2004072025A3 (de) | Substituierte n-arylheterozyklen, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel | |
MY141559A (en) | Triazole derivatives as tachykinin receptor antagonists | |
RS52142B (sr) | 8-[3-amino-piperidin-1-il]-ksantini, njihovo dobijanje i njihova primena kao farmaceutskih kompozicija | |
WO2005058884A3 (en) | Cyclopropane compounds and pharmaceutical use thereof | |
ATE396999T1 (de) | Morphinanderivate substituiert in position 14 und deren quartäre ammoniumsalze, herstellungsverfahren und verwendung | |
WO2005103037A3 (de) | Ausgewählte cgrp-antagonisten, verfahren zu deren herstellung sowie deren verwendung als arzneimittel | |
WO2004037811A8 (de) | Ausgewählte cgrp-antagonisten, verfahren zu deren herstellung sowie deren verwendung als arzneimittel | |
WO2001066534A3 (en) | Cyclic and bicyclic diamino histamine-3 receptor antagonists | |
SI1501808T1 (sl) | Antagonisti tahikininskega receptorja | |
EP2982668A3 (en) | 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors for the treatment of thromboembolic disorders | |
ATE332304T1 (de) | Cefdinir salze als zwischenprodukte | |
WO2006076452A8 (en) | An exo-selective synthesis of himbacine analogs | |
WO2004112704A3 (en) | Substituted piperidine compounds and methods of their use | |
DK0733051T3 (da) | Bicykliske, heterocykliske forbindelser som neurokinin A-antagonister | |
YU101103A (en) | Technical synthesis method for producing tropenol | |
WO2005087770A3 (de) | 5, 6-dihydrocarbyl-7-amino-triazolopyrimidine, verfahren zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen sowie sie enthaltende mittel | |
CA2235840A1 (en) | Phenylethanolamine compounds useful as .beta.3 agonist, process for producing the same, and intermediates in the production of the same | |
BR9806875A (pt) | Processo para a preparação de um composto. | |
ATE280769T1 (de) | Verfahren zur herstellung von vitronectin- rezeptorantagonisten | |
MX2007000042A (es) | Metodo para producir una forma enantiomerica de derivados de acido 2,3-diaminopropionico. | |
WO2003057668A1 (fr) | Derive de cetone cyclique azote, procede permettant de produire ce derive et utilisation de ce derive | |
AU2003259529A1 (en) | Process for preparing haloalkyl pyrimidines |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AL AM AT AU AZ BB BG BR BY CA CH CN CZ DE DK EE ES FI GB GE HU IL IS JP KE KG KR KZ LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK TJ TM TR TT UA UG US UZ VN AM AZ BY KG KZ MD RU TJ TM |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): KE LS MW SD SZ UG AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
ENP | Entry into the national phase |
Ref document number: 2235840 Country of ref document: CA Kind code of ref document: A Ref document number: 2235840 Country of ref document: CA |
|
WWE | Wipo information: entry into national phase |
Ref document number: PA/a/1998/003256 Country of ref document: MX Ref document number: PV1998-1265 Country of ref document: CZ Ref document number: 09065077 Country of ref document: US |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1019980703029 Country of ref document: KR |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1996935424 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
WWP | Wipo information: published in national office |
Ref document number: PV1998-1265 Country of ref document: CZ |
|
WWP | Wipo information: published in national office |
Ref document number: 1019980703029 Country of ref document: KR |
|
WWP | Wipo information: published in national office |
Ref document number: 1996935424 Country of ref document: EP |
|
WWG | Wipo information: grant in national office |
Ref document number: 1996935424 Country of ref document: EP |
|
WWR | Wipo information: refused in national office |
Ref document number: PV1998-1265 Country of ref document: CZ |
|
WWG | Wipo information: grant in national office |
Ref document number: 1019980703029 Country of ref document: KR |