WO1981001285A1 - Substituted carboxylic ceto-acids,process for the preparation thereof,use thereof and medicinal compositions containing them - Google Patents

Substituted carboxylic ceto-acids,process for the preparation thereof,use thereof and medicinal compositions containing them Download PDF

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Publication number
WO1981001285A1
WO1981001285A1 PCT/EP1980/000123 EP8000123W WO8101285A1 WO 1981001285 A1 WO1981001285 A1 WO 1981001285A1 EP 8000123 W EP8000123 W EP 8000123W WO 8101285 A1 WO8101285 A1 WO 8101285A1
Authority
WO
WIPO (PCT)
Prior art keywords
acids
salts
hydrogen atom
atom
group
Prior art date
Application number
PCT/EP1980/000123
Other languages
German (de)
English (en)
French (fr)
Inventor
G Ludwig
E Rapp
E Kraas
H Wolf
Original Assignee
Byk Gulden Lomberg Chem Fab
E Kraas
H Wolf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CA000360867A priority Critical patent/CA1158286A/en
Application filed by Byk Gulden Lomberg Chem Fab, E Kraas, H Wolf filed Critical Byk Gulden Lomberg Chem Fab
Priority to DE8080902059T priority patent/DE3069883D1/de
Publication of WO1981001285A1 publication Critical patent/WO1981001285A1/de
Priority to DK287881A priority patent/DK158460C/da
Priority to NO812229A priority patent/NO155770C/no
Priority to FI812050A priority patent/FI62820C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic System
    • C07F3/08—Cadmium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/88—Unsaturated compounds containing keto groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic System
    • C07F3/02—Magnesium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PCT/EP1980/000123 1979-10-31 1980-10-31 Substituted carboxylic ceto-acids,process for the preparation thereof,use thereof and medicinal compositions containing them WO1981001285A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA000360867A CA1158286A (en) 1980-02-04 1980-09-23 Parking brake system
DE8080902059T DE3069883D1 (en) 1979-10-31 1980-10-31 Substituted carboxylic ceto-acids, process for the preparation thereof, use thereof and medicinal compositions containing them
DK287881A DK158460C (da) 1979-10-31 1981-06-29 Analogifremgangsmaade til fremstilling af substituerede oxocarboxylsyrer
NO812229A NO155770C (no) 1979-10-31 1981-06-29 Analogifremgangsmaate ved fremstilling av terapeutisk aktive substituerte oksokarboksylsyrer.
FI812050A FI62820C (fi) 1979-10-31 1981-06-30 Foerfarande foer framstaellning av terapeutiskt anvaendbara sustituerade oxokarboxylsyror

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH978579 1979-10-31
CH9785/79 1979-10-31

Publications (1)

Publication Number Publication Date
WO1981001285A1 true WO1981001285A1 (en) 1981-05-14

Family

ID=4355617

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1980/000123 WO1981001285A1 (en) 1979-10-31 1980-10-31 Substituted carboxylic ceto-acids,process for the preparation thereof,use thereof and medicinal compositions containing them

Country Status (17)

Country Link
US (1) US4334089A (es)
EP (2) EP0051077A1 (es)
JP (1) JPH0231705B2 (es)
AU (1) AU542902B2 (es)
CA (1) CA1176273A (es)
DE (2) DE3069883D1 (es)
DK (1) DK158460C (es)
ES (1) ES8202780A1 (es)
FI (1) FI62820C (es)
GR (1) GR70727B (es)
HU (1) HU187337B (es)
IE (1) IE50471B1 (es)
IL (1) IL61371A (es)
NZ (1) NZ195415A (es)
PT (1) PT71998B (es)
WO (1) WO1981001285A1 (es)
ZA (1) ZA806681B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4518800A (en) * 1983-07-18 1985-05-21 Societe Francaise Hoechst Process for preparation of crystallized monohydrated sodium phenylpyruvate

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2481118A1 (fr) * 1980-04-24 1981-10-30 Roussel Uclaf Application a titre de medicaments de derives substitues de l'acide phenyl-4-oxo-2-butenoique
EP0134216A4 (en) * 1983-01-13 1985-07-01 Ethyl Corp METHOD FOR PRODUCING ALPHA KETO CARBONIC ACIDS.
JP2533651B2 (ja) * 1988-09-13 1996-09-11 財団法人相模中央化学研究所 ２―オキソ―３―芳香族カルボン酸誘導体の製造方法
US4912255A (en) * 1989-04-13 1990-03-27 Chan Albert S Process for preparing sodium phenylpyruvate from calcium phenylpyruvate
JPH0454806U (es) * 1990-09-18 1992-05-11
JPH05337913A (ja) * 1992-12-22 1993-12-21 Chichibu Cement Co Ltd 舗装用ブロック材の成形法及びその加熱装置
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
JP2006519229A (ja) * 2003-02-13 2006-08-24 アルバート・アインシュタイン・カレッジ・オヴ・メディシン・オヴ・イェシヴァ・ユニヴァーシティ 視床下部内の長鎖脂肪アシルＣｏＡレベルの変調による摂食量およびグルコース産生量の調節
WO2006041922A2 (en) * 2004-10-08 2006-04-20 Dara Biosciences, Inc. Agents and methods for administration to the central nervous system
WO2006088798A2 (en) * 2005-02-14 2006-08-24 Albert Einstein College Of Medicine Of Yeshiva University Modulation of hypothalamic atp-sensitive potassium channels
EP2852940A4 (en) * 2012-05-22 2016-06-29 Checkpoint Systems Inc TAG WITH SOLID HOUSING

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1810026A1 (de) * 1967-11-28 1969-10-16 Sun Oil Co 4-(2-Hydroxyphenyl)-2-ketobuttersaeuren und Verfahren zu ihrer Herstellung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3182061A (en) * 1961-03-20 1965-05-04 Warner Lambert Pharmaceutical 5-[4-(p-hydroxyphenoxy)phenyl]-5-oxo-3-methylvaleric acid
FR2127265A5 (es) * 1971-03-02 1972-10-13 Ugine Kuhlmann
JPS5227147B1 (es) * 1971-06-16 1977-07-19
US4029699A (en) * 1971-09-13 1977-06-14 Takeda Chemical Industries, Ltd. 3,(2,4,5-Trisubstituted benzoyl)-propionic acid and the salts thereof
DE2365755A1 (de) * 1972-09-12 1976-04-08 Sagami Chem Res Alpha-ketosaeurederivate und verfahren zu ihrer herstellung
JPS5116634A (en) * 1974-07-29 1976-02-10 Nisshin Flour Milling Co Pirubinsanno seizoho

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1810026A1 (de) * 1967-11-28 1969-10-16 Sun Oil Co 4-(2-Hydroxyphenyl)-2-ketobuttersaeuren und Verfahren zu ihrer Herstellung

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Journal of the American Chemical Society, Volume 5,, No. 11, November 1936 L.F. FIESER et al. "The Synthesis of phenanthrene and hydrophenanthrene derivatives V", Absatze 2319-2322 siehe Abstatze 2320-2321 in der anmeldung angefuhrt. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4518800A (en) * 1983-07-18 1985-05-21 Societe Francaise Hoechst Process for preparation of crystallized monohydrated sodium phenylpyruvate

Also Published As

Publication number Publication date
IE802250L (en) 1981-04-30
IE50471B1 (en) 1986-04-30
FI812050L (fi) 1981-06-30
JPS56501523A (es) 1981-10-22
DE3041097A1 (de) 1981-05-14
GR70727B (es) 1983-01-24
DK158460C (da) 1990-10-08
JPH0231705B2 (es) 1990-07-16
FI62820C (fi) 1983-03-10
IL61371A0 (en) 1980-12-31
AU542902B2 (en) 1985-03-21
PT71998A (en) 1980-11-01
CA1176273A (en) 1984-10-16
DK158460B (da) 1990-05-21
HU187337B (en) 1985-12-28
EP0038343A1 (de) 1981-10-28
ZA806681B (en) 1981-10-28
DE3069883D1 (en) 1985-02-07
DK287881A (da) 1981-06-29
NZ195415A (en) 1982-09-14
US4334089A (en) 1982-06-08
ES496382A0 (es) 1982-03-01
AU6398680A (en) 1981-05-22
ES8202780A1 (es) 1982-03-01
EP0038343B1 (de) 1984-12-27
EP0051077A1 (de) 1982-05-12
PT71998B (en) 1982-03-31
IL61371A (en) 1985-02-28
FI62820B (fi) 1982-11-30

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