UY33694A - ?inhibidores de n1/n2-lactama acetil-coa carboxilasa?. - Google Patents

?inhibidores de n1/n2-lactama acetil-coa carboxilasa?.

Info

Publication number
UY33694A
UY33694A UY0001033694A UY33694A UY33694A UY 33694 A UY33694 A UY 33694A UY 0001033694 A UY0001033694 A UY 0001033694A UY 33694 A UY33694 A UY 33694A UY 33694 A UY33694 A UY 33694A
Authority
UY
Uruguay
Prior art keywords
coa carboxylase
lactama
acetil
carboxylase inhibitors
inhibitors
Prior art date
Application number
UY0001033694A
Other languages
English (en)
Inventor
Scott William Bagley
David Andrew Griffith
Robert Lee Dow
Aaron Christopher Smith
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of UY33694A publication Critical patent/UY33694A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La invención proporciona un compuesto de Fórmula I, o una sal farmacéuticamente aceptable del mismo; en la que G es R1, R2 y R3 son como se han descrito en el presente documento; composiciones farmacéuticas del mismo; y el uso del mismo en el tratamiento de enfermedades, afecciones o trastornos modulados por la inhibición de una enzima o enzimas acetil-CoA carboxilasa(s) en un animal.
UY0001033694A 2010-10-29 2011-10-28 ?inhibidores de n1/n2-lactama acetil-coa carboxilasa?. UY33694A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40812710P 2010-10-29 2010-10-29
US201161531744P 2011-09-07 2011-09-07

Publications (1)

Publication Number Publication Date
UY33694A true UY33694A (es) 2012-05-31

Family

ID=44993633

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001033694A UY33694A (es) 2010-10-29 2011-10-28 ?inhibidores de n1/n2-lactama acetil-coa carboxilasa?.

Country Status (26)

Country Link
US (3) US8859773B2 (es)
EP (2) EP2952514A1 (es)
JP (2) JP5647356B2 (es)
KR (2) KR20150006899A (es)
CN (2) CN104774205A (es)
AR (1) AR083578A1 (es)
AU (1) AU2011322117B2 (es)
BR (1) BR112013010310A2 (es)
CA (1) CA2815169C (es)
CY (1) CY1116405T1 (es)
DK (1) DK2632925T3 (es)
ES (1) ES2546465T3 (es)
HK (2) HK1186724A1 (es)
HU (1) HUE025078T2 (es)
IL (1) IL225779A0 (es)
MX (1) MX2013004733A (es)
NZ (1) NZ609527A (es)
PL (1) PL2632925T3 (es)
PT (1) PT2632925E (es)
RU (1) RU2540337C2 (es)
SG (1) SG189883A1 (es)
SI (1) SI2632925T1 (es)
TW (3) TWI441823B (es)
UY (1) UY33694A (es)
WO (1) WO2012056372A1 (es)
ZA (1) ZA201303882B (es)

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KR20230013126A (ko) * 2020-05-21 2023-01-26 시오노기 앤드 컴파니, 리미티드 지방성 간질환의 치료용 의약
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Also Published As

Publication number Publication date
TWI441823B (zh) 2014-06-21
AR083578A1 (es) 2013-03-06
HK1209733A1 (en) 2016-04-08
SI2632925T1 (sl) 2015-07-31
IL225779A0 (en) 2013-06-27
HUE025078T2 (en) 2016-01-28
EP2952514A1 (en) 2015-12-09
CY1116405T1 (el) 2017-02-08
JP5647356B2 (ja) 2014-12-24
KR20150006899A (ko) 2015-01-19
JP2013542218A (ja) 2013-11-21
EP2632925B1 (en) 2015-05-27
US8993586B2 (en) 2015-03-31
CA2815169A1 (en) 2012-05-03
US20120108619A1 (en) 2012-05-03
US20150152109A1 (en) 2015-06-04
AU2011322117A1 (en) 2013-05-02
CN104774205A (zh) 2015-07-15
KR101529404B1 (ko) 2015-06-26
DK2632925T3 (en) 2015-06-29
SG189883A1 (en) 2013-06-28
MX2013004733A (es) 2013-07-02
TW201531472A (zh) 2015-08-16
PT2632925E (pt) 2015-09-01
CN103189377A (zh) 2013-07-03
ZA201303882B (en) 2014-02-26
BR112013010310A2 (pt) 2016-11-29
JP2015057416A (ja) 2015-03-26
TWI507406B (zh) 2015-11-11
ES2546465T3 (es) 2015-09-23
EP2632925A1 (en) 2013-09-04
TW201302751A (zh) 2013-01-16
HK1186724A1 (en) 2014-03-21
US20150025098A1 (en) 2015-01-22
NZ609527A (en) 2014-03-28
US8859773B2 (en) 2014-10-14
PL2632925T3 (pl) 2015-10-30
US9181252B2 (en) 2015-11-10
TW201418256A (zh) 2014-05-16
RU2013116924A (ru) 2014-12-10
KR20140014078A (ko) 2014-02-05
CA2815169C (en) 2015-10-06
CN103189377B (zh) 2015-02-25
RU2540337C2 (ru) 2015-02-10
AU2011322117B2 (en) 2015-01-22
WO2012056372A1 (en) 2012-05-03

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