UY33319A - PROTEÍNAS QUE SE UNEN AL TNF-a - Google Patents
PROTEÍNAS QUE SE UNEN AL TNF-aInfo
- Publication number
- UY33319A UY33319A UY0001033319A UY33319A UY33319A UY 33319 A UY33319 A UY 33319A UY 0001033319 A UY0001033319 A UY 0001033319A UY 33319 A UY33319 A UY 33319A UY 33319 A UY33319 A UY 33319A
- Authority
- UY
- Uruguay
- Prior art keywords
- antibodies
- tnf
- proteins
- join
- bind
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6845—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a cytokine, e.g. growth factors, VEGF, TNF, a lymphokine or an interferon
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- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1021—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against cytokines, e.g. growth factors, VEGF, TNF, lymphokines or interferons
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Abstract
Proteínas de unión aisladas, por ejemplo, anticuerpos o porciones de unión al antígeno de éstos, que se unen al factor de necrosis tumoral-alfa(TNF-a), por ejemplo, al TNF-a humano. Composiciones basadas en anticuerpos. Moléculas relacionadas. Compo siciones farmacéuticas que comprenden dichos anticuerpos. Métodos terapéuticos y de diagnóstico donde se emplean dichos anticuerpos.
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UY0001033319A UY33319A (es) | 2010-04-07 | 2011-04-07 | PROTEÍNAS QUE SE UNEN AL TNF-a |
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BRPI0906490A2 (pt) | 2008-01-15 | 2015-07-14 | Abbott Lab | Vetores de expressão de mamífero melhorados e uso dos mesmos |
WO2009134776A2 (en) | 2008-04-29 | 2009-11-05 | Abbott Laboratories | Dual variable domain immunoglobulins and uses thereof |
AU2009256250B2 (en) | 2008-06-03 | 2013-05-30 | Abbvie Inc. | Dual variable domain immunoglobulins and uses thereof |
EP2752428B8 (en) | 2008-06-25 | 2020-02-26 | Novartis Ag | Humanization of rabbit antibodies using a universal antibody framework |
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BRPI1013688A8 (pt) | 2009-03-05 | 2017-02-14 | Abbott Lab | Proteínas de ligação de il-17. |
UY32979A (es) | 2009-10-28 | 2011-02-28 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
UA107490C2 (uk) | 2010-04-07 | 2015-01-12 | Еббві Інк. | TNF-α-ЗВ'ЯЗУВАЛЬНИЙ БІЛОК |
SG188190A1 (en) | 2010-08-03 | 2013-04-30 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
AR084210A1 (es) | 2010-12-08 | 2013-05-02 | Abbott Lab | PROTEINAS DE UNION AL TNF-a |
MX2014004977A (es) | 2011-10-24 | 2014-09-11 | Abbvie Inc | Inmunoaglutinantes dirigidos contra esclerostina. |
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2011
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- 2011-04-06 BR BR112012025568A patent/BR112012025568A2/pt not_active IP Right Cessation
- 2011-04-06 PE PE2012002003A patent/PE20130528A1/es not_active Application Discontinuation
- 2011-04-06 JP JP2013503879A patent/JP2013523153A/ja active Pending
- 2011-04-06 AU AU2011237679A patent/AU2011237679B2/en not_active Ceased
- 2011-04-06 US US13/081,212 patent/US9226983B2/en active Active
- 2011-04-06 WO PCT/US2011/031381 patent/WO2011127141A1/en active Application Filing
- 2011-04-06 KR KR1020157005483A patent/KR20150038556A/ko not_active Application Discontinuation
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- 2011-04-06 MX MX2012011629A patent/MX2012011629A/es not_active Application Discontinuation
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2012
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2015
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SG184473A1 (en) | 2012-11-29 |
PE20130528A1 (es) | 2013-05-26 |
GT201200271A (es) | 2014-02-21 |
CL2012002783A1 (es) | 2013-07-12 |
IL222323A0 (en) | 2012-12-31 |
AU2011237679A1 (en) | 2012-11-01 |
US20160176958A1 (en) | 2016-06-23 |
MX2012011629A (es) | 2013-03-05 |
BR112012025568A2 (pt) | 2017-03-28 |
ECSP12012272A (es) | 2012-11-30 |
EP2555797A4 (en) | 2014-02-12 |
CN102958537A (zh) | 2013-03-06 |
US9226983B2 (en) | 2016-01-05 |
NZ603045A (en) | 2014-11-28 |
AR080840A1 (es) | 2012-05-09 |
US20110250130A1 (en) | 2011-10-13 |
EP2555797A1 (en) | 2013-02-13 |
RU2012147249A (ru) | 2014-05-20 |
TWI508745B (zh) | 2015-11-21 |
JP2013523153A (ja) | 2013-06-17 |
AU2011237679B2 (en) | 2014-11-06 |
KR20150038556A (ko) | 2015-04-08 |
WO2011127141A1 (en) | 2011-10-13 |
TW201138825A (en) | 2011-11-16 |
CA2795734A1 (en) | 2011-10-13 |
CN102958537B (zh) | 2015-09-16 |
KR20130010123A (ko) | 2013-01-25 |
CR20120506A (es) | 2013-02-15 |
UA107490C2 (uk) | 2015-01-12 |
CO6630164A2 (es) | 2013-03-01 |
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