UY25800A1 - Procedimiento para preparar composición farmacéutica de liberación modificada que comprende un sensibilizador de insulina. - Google Patents

Procedimiento para preparar composición farmacéutica de liberación modificada que comprende un sensibilizador de insulina.

Info

Publication number
UY25800A1
UY25800A1 UY25800A UY25800A UY25800A1 UY 25800 A1 UY25800 A1 UY 25800A1 UY 25800 A UY25800 A UY 25800A UY 25800 A UY25800 A UY 25800A UY 25800 A1 UY25800 A1 UY 25800A1
Authority
UY
Uruguay
Prior art keywords
insulin sensitizer
pharmaceutical composition
modified release
procedure
composition including
Prior art date
Application number
UY25800A
Other languages
English (en)
Inventor
Re Vincenzo
Skinner Janet Louise
Sauer Joseph
Muldoon William
Milosovich Susan Marie
Glinecke Robert
Original Assignee
Smithkline Beecham P L C Y Smi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9824870.1A external-priority patent/GB9824870D0/en
Priority claimed from GBGB9912189.9A external-priority patent/GB9912189D0/en
Application filed by Smithkline Beecham P L C Y Smi filed Critical Smithkline Beecham P L C Y Smi
Publication of UY25800A1 publication Critical patent/UY25800A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Un procedimiento para preparar una composición farmacéutica, que comprende formular el sensibilizador de insulina tiazolidinadiónico y el vehículo farmacéuticamente aceptable de modo que permita una liberación modificada del sensibilizador de insulina. Dicha composición es útil en el tratamiento de la diabetes mellitus de tipo 2.
UY25800A 1998-11-12 1999-11-15 Procedimiento para preparar composición farmacéutica de liberación modificada que comprende un sensibilizador de insulina. UY25800A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9824870.1A GB9824870D0 (en) 1998-11-12 1998-11-12 Novel composition and use
GBGB9912189.9A GB9912189D0 (en) 1999-05-25 1999-05-25 Novel composition and use

Publications (1)

Publication Number Publication Date
UY25800A1 true UY25800A1 (es) 2000-08-21

Family

ID=26314667

Family Applications (2)

Application Number Title Priority Date Filing Date
UY25798A UY25798A1 (es) 1998-11-12 1999-11-12 Composición farmacéutica de liberación modificada que comprende un sensibilizador de insulina tiazolidinadiónico.
UY25800A UY25800A1 (es) 1998-11-12 1999-11-15 Procedimiento para preparar composición farmacéutica de liberación modificada que comprende un sensibilizador de insulina.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
UY25798A UY25798A1 (es) 1998-11-12 1999-11-12 Composición farmacéutica de liberación modificada que comprende un sensibilizador de insulina tiazolidinadiónico.

Country Status (39)

Country Link
EP (3) EP1128827B1 (es)
JP (1) JP2002529505A (es)
KR (2) KR100732599B1 (es)
CN (1) CN1289081C (es)
AP (2) AP2008004490A0 (es)
AR (2) AR023699A1 (es)
AT (1) ATE382352T1 (es)
AU (1) AU768578B2 (es)
BG (2) BG65444B1 (es)
BR (1) BR9915215A (es)
CA (1) CA2350659C (es)
CO (1) CO5190673A1 (es)
CY (1) CY1107909T1 (es)
CZ (1) CZ20011628A3 (es)
DE (1) DE69937898T2 (es)
DK (1) DK1128827T3 (es)
DZ (1) DZ2937A1 (es)
EA (3) EA200702648A1 (es)
EG (2) EG24463A (es)
ES (1) ES2299269T3 (es)
HK (1) HK1040909B (es)
HR (2) HRP20010342B1 (es)
HU (1) HUP0104307A3 (es)
ID (1) ID29344A (es)
IL (2) IL143003A0 (es)
MY (1) MY135973A (es)
NO (1) NO20012351L (es)
NZ (2) NZ511611A (es)
OA (1) OA11676A (es)
PE (1) PE20001428A1 (es)
PL (1) PL198717B1 (es)
PT (1) PT1128827E (es)
RS (1) RS50208B (es)
SI (1) SI1128827T1 (es)
SK (1) SK286937B6 (es)
TR (2) TR200101337T2 (es)
TW (2) TWI257305B (es)
UY (2) UY25798A1 (es)
WO (1) WO2000028990A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6099862A (en) * 1998-08-31 2000-08-08 Andrx Corporation Oral dosage form for the controlled release of a biguanide and sulfonylurea
AR030920A1 (es) 1999-11-16 2003-09-03 Smithkline Beecham Plc Composiciones farmaceuticas para el tratamiento de la diabetes mellitus y condiciones asociadas con la diabetes mellitus, y procedimientos para preparar dichas composiciones
US20010026800A1 (en) * 2000-01-07 2001-10-04 Michael Jacob G. Selective activation of a TH1 or TH2 lymphocyte regulated immune response
CA2403670C (en) * 2001-01-31 2010-02-09 Rohm Gmbh & Co. Kg Multiparticulate drug form comprising at least two differently coated pellet forms
AU2002367154A1 (en) * 2001-12-21 2003-07-15 Smithkline Beecham Corporation Dosing regimen for ppar-gamma activators
MY139719A (en) * 2002-02-12 2009-10-30 Glaxo Group Ltd Oral dosage form for controlled drug release
CN100367960C (zh) * 2002-07-11 2008-02-13 武田药品工业株式会社 包衣制剂的制备方法
US7018658B2 (en) * 2002-11-14 2006-03-28 Synthon Bv Pharmaceutical pellets comprising tamsulosin
CA2514879C (en) * 2003-01-03 2014-09-16 Shire Laboratories Inc. Two or more enteric materials to regulate drug release
CA2514539C (en) 2003-01-29 2012-03-06 Takeda Pharmaceutical Company Limited Process for producing coated preparation
ES2241478B1 (es) * 2004-02-13 2006-11-16 Lacer S.A. Preparacion farmaceutica para la liberacion sostenida de un principio farmaceuticamente activo.
FI20060501L (fi) * 2006-05-22 2007-11-23 Biohit Oyj Koostumus ja menetelmä asetaldehydin sitomiseksi vatsassa
CN103945832B (zh) * 2011-07-14 2017-03-29 能脑有限责任公司 用于脑能量分子延迟释放和持续释放的组合物，装置及方法
CA2936748C (en) 2014-10-31 2017-08-08 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS5697277A (en) 1980-01-07 1981-08-05 Takeda Chem Ind Ltd Thiazolidine derivative
JPS6051189A (ja) 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
US4582839A (en) 1984-03-21 1986-04-15 Takeda Chemical Industries, Ltd. 2,4-thiazolidinediones
CN1003445B (zh) 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物，其制备方法和用途
DK173350B1 (da) 1985-02-26 2000-08-07 Sankyo Co Thiazolidinderivater, deres fremstilling og farmaceutisk paæparat indeholdende dem
JPH06779B2 (ja) 1985-06-10 1994-01-05 武田薬品工業株式会社 チアゾリジオン誘導体およびそれを含んでなる医薬組成物
US4812570A (en) 1986-07-24 1989-03-14 Takeda Chemical Industries, Ltd. Method for producing thiazolidinedione derivatives
SG59988A1 (en) * 1987-09-04 1999-02-22 Beecham Group Plc Substituted thiazolidinedione derivatives
US4791125A (en) 1987-12-02 1988-12-13 Pfizer Inc. Thiazolidinediones as hypoglycemic and anti-atherosclerosis agents
WO1989008651A1 (en) 1988-03-08 1989-09-21 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
US5061717A (en) 1988-03-08 1991-10-29 Pfizer Inc. Thiazolidinedione hypoglycemic agents
WO1991007107A1 (en) 1989-11-13 1991-05-30 Pfizer Inc. Oxazolidinedione hypoglycemic agents
US5089514A (en) 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
AU650465B2 (en) 1990-07-03 1994-06-23 Yamanouchi Pharmaceutical Co., Ltd. Bisheterocyclic compound
DE69106714T2 (de) 1990-08-23 1995-05-11 Pfizer Hypoglykämische hydroxyharnstoffderivate.
JPH04210683A (ja) 1990-12-06 1992-07-31 Terumo Corp チアゾリジン−２，４−ジオン誘導体およびこれを含有する糖尿病合併症治療薬
US5183823A (en) 1991-04-11 1993-02-02 Takeda Chemical Industries, Ltd. Pyridine n-oxide compounds which are useful as hypoglycemic and hypolipidemic agents
SK109993A3 (en) 1991-04-11 1994-12-07 Upjohn Co Thiazolidinedione derivatives producing and use thereof
US5502078A (en) * 1991-05-28 1996-03-26 Zeneca Limited Chemical compounds
TW222626B (es) 1991-07-22 1994-04-21 Pfizer
FR2680512B1 (fr) 1991-08-20 1995-01-20 Adir Nouveaux derives de 2,4-thiazolidinedione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
JPH05271204A (ja) 1992-03-26 1993-10-19 Japan Tobacco Inc 新規なトリアジン誘導体
US5264451A (en) 1992-04-07 1993-11-23 American Home Products Corporation Process for treating hyperglycemia using trifluoromethyl substituted 3H-pyrazol-3-ones
AU3959193A (en) 1992-04-10 1993-11-18 Smithkline Beecham Plc Heterocyclic compounds and their use in the treatment of type II-diabetes
WO1993022445A1 (en) 1992-05-05 1993-11-11 The Upjohn Company A process for producing pioglitazone metabolite
PL176885B1 (pl) 1992-07-03 1999-08-31 Smithkline Beecham Plc Kompozycja farmaceutyczna
US5326770A (en) * 1992-07-17 1994-07-05 The Du Pont Merck Pharmaceutical Company Monoamine oxidase-B (MAO-B) inhibitory 5-substituted 2,4-thiazolidinediones useful in treating memory disorders of mammals
US5232945A (en) 1992-07-20 1993-08-03 Pfizer Inc. 3-aryl-2-hydroxypropionic acid derivatives and analogs as antihypertensives
GB9218830D0 (en) 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
US5478852C1 (en) * 1993-09-15 2001-03-13 Sankyo Co Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus
DE4432757A1 (de) * 1994-09-14 1996-03-21 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung
TWI238064B (en) * 1995-06-20 2005-08-21 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
US5840332A (en) * 1996-01-18 1998-11-24 Perio Products Ltd. Gastrointestinal drug delivery system
JP3256841B2 (ja) * 1996-06-27 2002-02-18 武田薬品工業株式会社 ベンズアルデヒド化合物の製造法
US5952509A (en) * 1996-06-27 1999-09-14 Takeda Chemical Industries, Ltd. Production of benzaldehyde compounds
GB9619757D0 (en) * 1996-09-21 1996-11-06 Knoll Ag Chemical process
IL132032A0 (en) * 1997-03-24 2001-03-19 Galderma Res & Dev Retinoid related molecules for the treatment of non-insulin dependent diabetes mellitus

Also Published As

Publication number Publication date
DK1128827T3 (da) 2008-04-28
HRP20010342B1 (en) 2008-04-30
NZ526440A (en) 2005-01-28
TR200503846T2 (tr) 2007-01-22
PE20001428A1 (es) 2001-02-08
PL348153A1 (en) 2002-05-06
KR100732599B1 (ko) 2007-06-27
ID29344A (id) 2001-08-23
OA11676A (en) 2005-01-12
AR023699A1 (es) 2002-09-04
EA200702648A1 (ru) 2008-10-30
SI1128827T1 (sl) 2008-06-30
JP2002529505A (ja) 2002-09-10
BG65444B1 (bg) 2008-08-29
DE69937898D1 (de) 2008-02-14
UY25798A1 (es) 2000-12-29
HK1040909B (zh) 2008-08-01
HK1040909A1 (en) 2002-06-28
EP1815855A1 (en) 2007-08-08
TR200101337T2 (tr) 2001-11-21
PT1128827E (pt) 2008-03-10
AU1272900A (en) 2000-06-05
SK6432001A3 (en) 2001-12-03
NZ511611A (en) 2003-10-31
AP2008004490A0 (en) 2008-06-30
CY1107909T1 (el) 2013-09-04
BG109893A (bg) 2008-11-28
CA2350659C (en) 2009-06-09
IL143003A0 (en) 2002-04-21
EA200601144A1 (ru) 2007-02-27
NO20012351L (no) 2001-07-04
CN1289081C (zh) 2006-12-13
AP1901A (en) 2008-10-24
CA2350659A1 (en) 2000-05-25
CO5190673A1 (es) 2002-08-29
CZ20011628A3 (cs) 2001-12-12
DE69937898T2 (de) 2009-01-02
DZ2937A1 (fr) 2004-03-15
EP1128827A1 (en) 2001-09-05
BR9915215A (pt) 2001-07-31
PL198717B1 (pl) 2008-07-31
BG105570A (en) 2002-02-28
WO2000028990A1 (en) 2000-05-25
EP1128827B1 (en) 2008-01-02
CN1333683A (zh) 2002-01-30
HUP0104307A2 (hu) 2002-07-29
ATE382352T1 (de) 2008-01-15
KR20010073229A (ko) 2001-07-31
EA007608B1 (ru) 2006-12-29
YU36401A (sh) 2004-05-12
TW200505436A (en) 2005-02-16
AR023700A1 (es) 2002-09-04
RS50208B (sr) 2009-07-15
KR20060097140A (ko) 2006-09-13
ES2299269T3 (es) 2008-05-16
EG24463A (en) 2009-07-16
HRP20010342A2 (en) 2002-06-30
TWI246920B (en) 2006-01-11
HRP20080117A2 (en) 2008-10-31
IL183972A0 (en) 2007-10-31
SK286937B6 (sk) 2009-07-06
HUP0104307A3 (en) 2003-12-29
EA200100540A1 (ru) 2001-10-22
AU768578B2 (en) 2003-12-18
TWI257305B (en) 2006-07-01
EP1917962A1 (en) 2008-05-07
NO20012351D0 (no) 2001-05-11
MY135973A (en) 2008-07-31
EG22344A (en) 2002-12-31

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