US20150315234A1 - Myoblast differentiation promoter - Google Patents

Myoblast differentiation promoter Download PDF

Info

Publication number
US20150315234A1
US20150315234A1 US14/382,700 US201314382700A US2015315234A1 US 20150315234 A1 US20150315234 A1 US 20150315234A1 US 201314382700 A US201314382700 A US 201314382700A US 2015315234 A1 US2015315234 A1 US 2015315234A1
Authority
US
United States
Prior art keywords
hyp
gly
pro
peptide
ala
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US14/382,700
Other languages
English (en)
Inventor
Seiko Koizumi
Fumihito Sugihara
Naoki Inoue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nitta Gelatin Inc
Original Assignee
Nitta Gelatin Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nitta Gelatin Inc filed Critical Nitta Gelatin Inc
Assigned to NITTA GELATIN INC. reassignment NITTA GELATIN INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: INOUE, NAOKI, KOIZUMI, SEIKO, SUGIHARA, FUMIHITO
Publication of US20150315234A1 publication Critical patent/US20150315234A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A23K1/1631—
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A23K20/147—Polymeric derivatives, e.g. peptides or proteins
    • A23L1/3053—
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043—Leu-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0823—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Animal Husbandry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
US14/382,700 2012-12-13 2013-12-12 Myoblast differentiation promoter Abandoned US20150315234A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012272110 2012-12-13
JP2012-272110 2012-12-13
PCT/JP2013/083324 WO2014092150A1 (ja) 2012-12-13 2013-12-12 筋芽細胞分化促進剤

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2013/083324 A-371-Of-International WO2014092150A1 (ja) 2012-12-13 2013-12-12 筋芽細胞分化促進剤

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US15/299,172 Continuation US10632177B2 (en) 2012-12-13 2016-10-20 Myoblast differentiation promoter

Publications (1)

Publication Number Publication Date
US20150315234A1 true US20150315234A1 (en) 2015-11-05

Family

ID=50934433

Family Applications (2)

Application Number Title Priority Date Filing Date
US14/382,700 Abandoned US20150315234A1 (en) 2012-12-13 2013-12-12 Myoblast differentiation promoter
US15/299,172 Active 2034-11-13 US10632177B2 (en) 2012-12-13 2016-10-20 Myoblast differentiation promoter

Family Applications After (1)

Application Number Title Priority Date Filing Date
US15/299,172 Active 2034-11-13 US10632177B2 (en) 2012-12-13 2016-10-20 Myoblast differentiation promoter

Country Status (4)

Country Link
US (2) US20150315234A1 (zh)
JP (1) JP6407029B2 (zh)
CN (1) CN104271144B (zh)
WO (1) WO2014092150A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102348361B1 (ko) * 2015-09-15 2022-01-11 (주)아모레퍼시픽 아미노산을 함유하는 근세포 분화 촉진용 조성물
JP6877924B2 (ja) * 2016-09-07 2021-05-26 新田ゼラチン株式会社 表皮細胞間機能強化剤
CN107759660A (zh) * 2017-12-05 2018-03-06 陕西慧康生物科技有限责任公司 一种三肽‑29的液‑固相合成方法
JPWO2021015040A1 (zh) * 2019-07-25 2021-01-28
WO2023022174A1 (ja) * 2021-08-18 2023-02-23 株式会社 ニッピ 筋肉疲労および／または即発性筋肉痛を抑制する食品組成物
CN113929769B (zh) * 2021-09-07 2023-11-28 中国科学院理化技术研究所 一种促进成肌细胞增殖的活性肽及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110021590A1 (en) * 2009-06-05 2011-01-27 Link Medicine Corporation Aminopyrrolidinone derivatives and uses thereof
WO2012102308A1 (ja) * 2011-01-27 2012-08-02 新田ゼラチン株式会社 糖尿病の治療または予防剤

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002255847A (ja) * 2001-02-26 2002-09-11 Miyagi Kagaku Kogyo Kk コラーゲン産生促進剤、それを含む機能性食品および医薬品
AU2003221582A1 (en) 2002-05-03 2003-11-17 Millenium Biologix Inc. Connective tissue stimulating peptides
JP4286513B2 (ja) * 2002-09-26 2009-07-01 株式会社ファンケル 抗老化用組成物
WO2007017671A1 (en) * 2005-08-09 2007-02-15 Cambridge Enterprise Limited Collagen peptides, methods and uses
JP2008156294A (ja) 2006-12-25 2008-07-10 Lion Corp 筋芽細胞活性化剤
WO2009035169A1 (ja) * 2007-09-14 2009-03-19 Nippon Meat Packers, Inc. 血圧上昇抑制作用を有するぺプチド
JP4995155B2 (ja) * 2008-07-23 2012-08-08 株式会社ディーエイチシー 生体コラーゲン合成促進剤並びに生体コラーゲン合成促進用化粧品及び医薬部外品
JP4490498B2 (ja) * 2008-09-30 2010-06-23 新田ゼラチン株式会社 疾病抑制剤
US20120040055A1 (en) 2009-04-28 2012-02-16 Meiji Co., Ltd. Collagen peptide composition having good ability to enter the blood and food or beverage containing the same
JP2013227228A (ja) * 2012-04-24 2013-11-07 Jnc Corp 筋肉増加剤

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110021590A1 (en) * 2009-06-05 2011-01-27 Link Medicine Corporation Aminopyrrolidinone derivatives and uses thereof
WO2012102308A1 (ja) * 2011-01-27 2012-08-02 新田ゼラチン株式会社 糖尿病の治療または予防剤
US20130303448A1 (en) * 2011-01-27 2013-11-14 Nitta Gelatin Inc. Therapeutic or Preventive Agent for Diabetes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Zammit et al. The skeletal muscle satellite cell: the stem cell that came in from the cold. J Histochem Cytochem. 2006 Nov;54(11):1177-91. Epub 2006 Aug 9. *

Also Published As

Publication number Publication date
CN104271144A (zh) 2015-01-07
US20170035858A1 (en) 2017-02-09
CN104271144B (zh) 2018-06-26
WO2014092150A1 (ja) 2014-06-19
JP6407029B2 (ja) 2018-10-17
US10632177B2 (en) 2020-04-28
JPWO2014092150A1 (ja) 2017-01-12

Similar Documents

Publication Publication Date Title
US10632177B2 (en) Myoblast differentiation promoter
EA021974B1 (ru) Противовирусное соединение
KR20110091702A (ko) Ａｐｊ 수용체 화합물
KR20110093832A (ko) Ｃｘｃｒ4 수용체 화합물
EP2851084B1 (en) Modulation of the Vps10p-domain receptors for the treatment of cardiovascular disease
JP2012504619A (ja) 肥満および糖尿病の有望な治療薬としてのグレリンｏ−アシルトランスフェラーゼ阻害剤の合成方法および使用方法
CA3226492A1 (en) Bicyclic peptide inhibitors of interleukin-23 receptor
KR20150037815A (ko) 산소 부족 및 공기압 감소에 인한 고산병의 폐 형태의 치료를 위한 약학 조성물
CA3226539A1 (en) Peptide inhibitors of interleukin-23 receptor
KR20220124196A (ko) 사이클릭 펩티드 수용체 란티오닌 신테타제 c-유사 단백질 (lancl) 및 이의 용도
CN108712913A (zh) 内体g蛋白-偶联的受体的三部分调节剂
KR102268955B1 (ko) 항분비 인자 17
WO2019007072A1 (zh) Y肽在制备降血压药物或保健品中的应用
WO2021200259A1 (ja) Ｖｉｐｒ２アンタゴニストペプチド
US20220195016A1 (en) Biological and synthetic molecules inhibiting respiratory syncytial virus infection
KR20220110789A (ko) 칼슘 감지 수용체 효능제 화합물 및 이의 응용
AU759203B2 (en) Peptide having preptin functionality
RU2697515C2 (ru) Циклические аналоги апелина
US20190022181A1 (en) Mutant Peptides And Methods Of Treating Subjects Using The Same
CN104619333B (zh) 经修饰的肽，cb受体的配体，用于评估与cb受体结合的试剂盒、体外方法，用于调节cb受体活性的药物组合物、用途
WO2020230780A1 (ja) Ｒａｓ阻害ペプチド
JP7032808B2 (ja) ペプチドもしくはその薬学的に許容される塩、またはそれらのプロドラッグ
Sun et al. Design, synthesis and evaluation of novel 2-Hydroxypyrrolobenzodiazepine-5, 11-dione analogues as potent angiotensin converting enzyme (ACE) inhibitors
US20130109615A1 (en) Methods for inhibiting necrosis
US9670250B2 (en) Alpha-helical peptidomimetic inhibitors and methods using same

Legal Events

Date Code Title Description
AS Assignment

Owner name: NITTA GELATIN INC., JAPAN

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:KOIZUMI, SEIKO;SUGIHARA, FUMIHITO;INOUE, NAOKI;REEL/FRAME:033665/0473

Effective date: 20140722

STCB Information on status: application discontinuation

Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION