UA77273C2 - 3-heteroaryl-3,5-dihydro-4oxo-4h-pyridazino[4,5-?]indol-1-acetamide derivatives, their production and therapeutic use - Google Patents
3-heteroaryl-3,5-dihydro-4oxo-4h-pyridazino[4,5-?]indol-1-acetamide derivatives, their production and therapeutic use Download PDFInfo
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- UA77273C2 UA77273C2 UA20041008012A UA20041008012A UA77273C2 UA 77273 C2 UA77273 C2 UA 77273C2 UA 20041008012 A UA20041008012 A UA 20041008012A UA 20041008012 A UA20041008012 A UA 20041008012A UA 77273 C2 UA77273 C2 UA 77273C2
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- alkyl
- compound
- general formula
- atom
- hydrogen
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/04—Antipruritics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0204158A FR2838124B1 (fr) | 2002-04-03 | 2002-04-03 | Derives de 3-heteroaryl-3,5-dihydro-4-oxo-4h-pyridazino [4,5-b]indole-1-acetamide, leur preparation et leur application en therapeutique |
PCT/FR2003/001027 WO2003082874A2 (fr) | 2002-04-03 | 2003-04-02 | DERIVES DE 3-HETEROARYL-3,5-DIHYDRO-4-OXO-4H-PYRIDAZINO[4,5-b]INDOLE-1-ACETAMIDE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE |
Publications (1)
Publication Number | Publication Date |
---|---|
UA77273C2 true UA77273C2 (en) | 2006-11-15 |
Family
ID=28052083
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UA20041008012A UA77273C2 (en) | 2002-04-03 | 2003-02-04 | 3-heteroaryl-3,5-dihydro-4oxo-4h-pyridazino[4,5-?]indol-1-acetamide derivatives, their production and therapeutic use |
Country Status (29)
Country | Link |
---|---|
US (4) | US7235554B2 (is) |
EP (1) | EP1492792B1 (is) |
JP (2) | JP4575670B2 (is) |
KR (1) | KR100975999B1 (is) |
CN (2) | CN100406459C (is) |
AT (1) | ATE321763T1 (is) |
AU (1) | AU2003240930B2 (is) |
BR (1) | BR0309018A (is) |
CA (1) | CA2481460C (is) |
CY (1) | CY1104998T1 (is) |
DE (1) | DE60304327T2 (is) |
DK (1) | DK1492792T3 (is) |
EA (1) | EA007219B1 (is) |
ES (1) | ES2261940T3 (is) |
FR (1) | FR2838124B1 (is) |
HK (2) | HK1102371A1 (is) |
HR (1) | HRP20040911B1 (is) |
IL (2) | IL164257A0 (is) |
IS (1) | IS2483B (is) |
ME (2) | MEP23708A (is) |
MX (1) | MXPA04009635A (is) |
NO (1) | NO329426B1 (is) |
NZ (1) | NZ535741A (is) |
PL (1) | PL372617A1 (is) |
PT (1) | PT1492792E (is) |
RS (1) | RS51244B (is) |
UA (1) | UA77273C2 (is) |
WO (1) | WO2003082874A2 (is) |
ZA (1) | ZA200407945B (is) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE518954T1 (de) * | 2004-08-18 | 2011-08-15 | Lorus Therapeutics Inc | Kleine interferierende rna-moleküle gegen ribonukleotidreduktase und ihre verwendungen |
US7687501B2 (en) * | 2005-08-19 | 2010-03-30 | Schering Corporation | Pyridothienopyridazinone derivatives as mGluR1 antagonists |
WO2010087770A1 (en) * | 2009-01-30 | 2010-08-05 | Astrazeneca Ab | Novel process for preparing carboxy-containing pyrazoleamido compounds 597 |
CN105330665B (zh) * | 2015-11-04 | 2017-10-03 | 衡阳师范学院 | 一种抑制激肽释放酶klk7的化合物、制备方法和用途 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2754262B1 (fr) * | 1996-10-08 | 1998-10-30 | Synthelabo | Derives de 1h-pyrido[3,4-b]indole-4-carboxamide, leur preparation et leur application en therapeutique |
FR2766823B1 (fr) * | 1997-07-30 | 1999-10-08 | Synthelabo | Derives de 4-oxo-3,5-dihydro-4h-pyridazino[4,5-b] indole-1-acetamide, leur preparation et leur application en therapeutique |
FR2788696B1 (fr) * | 1999-01-26 | 2004-03-05 | Synthelabo | Utilisation de derives de pyridazino [4,5-b] indole-1-acetamide pour la preparation de medicaments destines aux maladies du systeme nerveux central |
FR2788776B1 (fr) * | 1999-01-26 | 2001-02-23 | Synthelabo | Derives de 4-oxo-3, 5-dihydro-4h-pyridazino [4,5-b] indole-1 -carboxamide, leur preparation et leur application en therapeutique |
FR2811990A1 (fr) * | 2000-07-24 | 2002-01-25 | Sanofi Synthelabo | DERIVES DE 1-(4-OXO-3,5-DIHYDRO-4H-PYRIDAZINO[4,5-b]INDOLE-1 -CARBONYL)PIPERAZINE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE |
FR2811897A1 (fr) * | 2000-07-24 | 2002-01-25 | Sanofi Synthelabo | UTILISATION DE DERIVES DE PYRIDAZINO[4,5-b]INDOLE-1- ACETAMIDE POUR LA PREPARATION DE MEDICAMENTS DESTINES AU TRAITEMENT DES DYSFONCTIONNEMENTS DES RECEPTEURS DE TYPE PERIPHERIQUE AUX BENZODIAZEPINES |
FR2833953B1 (fr) * | 2001-12-21 | 2004-12-03 | Sanofi Synthelabo | DERIVES DE 3-HETEROARYL-3,5-DIHYDRO-4-OXO-4H-PYRIDAZINO [4,5-b]INDOLE-1-CARBOXAMIDE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE |
-
2002
- 2002-04-03 FR FR0204158A patent/FR2838124B1/fr not_active Expired - Fee Related
-
2003
- 2003-02-04 UA UA20041008012A patent/UA77273C2/uk unknown
- 2003-04-02 AU AU2003240930A patent/AU2003240930B2/en not_active Ceased
- 2003-04-02 RS YUP-869/04A patent/RS51244B/sr unknown
- 2003-04-02 KR KR1020047015629A patent/KR100975999B1/ko not_active IP Right Cessation
- 2003-04-02 EP EP03730299A patent/EP1492792B1/fr not_active Expired - Lifetime
- 2003-04-02 MX MXPA04009635A patent/MXPA04009635A/es active IP Right Grant
- 2003-04-02 WO PCT/FR2003/001027 patent/WO2003082874A2/fr active Application Filing
- 2003-04-02 DK DK03730299T patent/DK1492792T3/da active
- 2003-04-02 NZ NZ535741A patent/NZ535741A/en not_active IP Right Cessation
- 2003-04-02 AT AT03730299T patent/ATE321763T1/de active
- 2003-04-02 PT PT03730299T patent/PT1492792E/pt unknown
- 2003-04-02 JP JP2003580339A patent/JP4575670B2/ja not_active Expired - Fee Related
- 2003-04-02 CN CNB038122227A patent/CN100406459C/zh not_active Expired - Fee Related
- 2003-04-02 ME MEP-237/08A patent/MEP23708A/xx unknown
- 2003-04-02 ES ES03730299T patent/ES2261940T3/es not_active Expired - Lifetime
- 2003-04-02 DE DE60304327T patent/DE60304327T2/de not_active Expired - Lifetime
- 2003-04-02 CN CNB2006101003182A patent/CN100543016C/zh not_active Expired - Fee Related
- 2003-04-02 BR BR0309018-3A patent/BR0309018A/pt not_active IP Right Cessation
- 2003-04-02 EA EA200401146A patent/EA007219B1/ru not_active IP Right Cessation
- 2003-04-02 ME MEP-2008-237A patent/ME00081B/me unknown
- 2003-04-02 US US10/509,695 patent/US7235554B2/en not_active Expired - Lifetime
- 2003-04-02 CA CA2481460A patent/CA2481460C/en not_active Expired - Fee Related
- 2003-04-02 IL IL16425703A patent/IL164257A0/xx unknown
- 2003-04-02 PL PL03372617A patent/PL372617A1/xx unknown
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2004
- 2004-09-23 IL IL164257A patent/IL164257A/en not_active IP Right Cessation
- 2004-09-30 NO NO20044153A patent/NO329426B1/no not_active IP Right Cessation
- 2004-09-30 IS IS7478A patent/IS2483B/is unknown
- 2004-10-01 ZA ZA2004/07945A patent/ZA200407945B/en unknown
- 2004-10-04 HR HRP20040911 patent/HRP20040911B1/xx not_active IP Right Cessation
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2005
- 2005-10-04 HK HK07108859.6A patent/HK1102371A1/xx not_active IP Right Cessation
- 2005-10-04 HK HK05108771A patent/HK1074632A1/xx not_active IP Right Cessation
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2006
- 2006-06-29 CY CY20061100885T patent/CY1104998T1/el unknown
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2007
- 2007-05-16 US US11/749,342 patent/US7323467B2/en not_active Expired - Lifetime
- 2007-10-04 US US11/867,366 patent/US7405306B2/en not_active Expired - Fee Related
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2008
- 2008-06-20 US US12/143,059 patent/US20080255129A1/en not_active Abandoned
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2010
- 2010-06-22 JP JP2010141683A patent/JP5277208B2/ja not_active Expired - Fee Related
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