UA68326C2 - An attenuated strain of the virus causing the porcine reproductive and respiratory syndrom (prrs), a vaccine for porcine protection from prrs, a method for preparation of active vaccine against prrs - Google Patents
An attenuated strain of the virus causing the porcine reproductive and respiratory syndrom (prrs), a vaccine for porcine protection from prrs, a method for preparation of active vaccine against prrs Download PDFInfo
- Publication number
- UA68326C2 UA68326C2 UA97105158A UA97105158A UA68326C2 UA 68326 C2 UA68326 C2 UA 68326C2 UA 97105158 A UA97105158 A UA 97105158A UA 97105158 A UA97105158 A UA 97105158A UA 68326 C2 UA68326 C2 UA 68326C2
- Authority
- UA
- Ukraine
- Prior art keywords
- virus
- strain
- vaccine
- prrs
- attenuated
- Prior art date
Links
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10061—Methods of inactivation or attenuation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/815—Viral vaccine for porcine species, e.g. swine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Mycology (AREA)
- Analytical Chemistry (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES09600168A ES2102971B1 (es) | 1996-01-25 | 1996-01-25 | Nueva cepa atenuada del virus causante del sindrome respiratorio y reproductivo porcino (prrs), las vacunas y medios de diagnostico obtenibles con la misma y los procedimientos para su obtencion. |
| PCT/ES1996/000234 WO1997027288A1 (es) | 1996-01-25 | 1996-12-04 | Nueva cepa atenuada del virus causante del sindrome respiratorio y reproductivo porcino (prrs), las vacunas y medios de diagnostico obtenibles con la misma y los procedimientos para su obtencion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA68326C2 true UA68326C2 (en) | 2004-08-16 |
Family
ID=8293550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA97105158A UA68326C2 (en) | 1996-01-25 | 1996-04-12 | An attenuated strain of the virus causing the porcine reproductive and respiratory syndrom (prrs), a vaccine for porcine protection from prrs, a method for preparation of active vaccine against prrs |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6001370A (pt) |
| EP (1) | EP0835929A1 (pt) |
| JP (1) | JP3068204B2 (pt) |
| KR (1) | KR19980703268A (pt) |
| CN (1) | CN1185806A (pt) |
| BR (1) | BR9604888A (pt) |
| CA (1) | CA2216436A1 (pt) |
| CZ (1) | CZ286766B6 (pt) |
| ES (1) | ES2102971B1 (pt) |
| HU (1) | HUP9801124A3 (pt) |
| PL (1) | PL185841B1 (pt) |
| UA (1) | UA68326C2 (pt) |
| WO (1) | WO1997027288A1 (pt) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2103460C (en) * | 1991-06-06 | 2000-09-26 | Gert Wensvoort | Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits |
| US5695766A (en) * | 1992-10-30 | 1997-12-09 | Iowa State University Research Foundation | Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome |
| US6773908B1 (en) * | 1992-10-30 | 2004-08-10 | Iowa State University Research Foundation, Inc. | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) |
| US6380376B1 (en) * | 1992-10-30 | 2002-04-30 | Iowa State University Research Foundation | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) |
| US6592873B1 (en) | 1992-10-30 | 2003-07-15 | Iowa State University Research Foundation, Inc. | Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids |
| US20040224327A1 (en) * | 1996-10-30 | 2004-11-11 | Meulenberg Johanna Jacoba Maria | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| EP0839912A1 (en) * | 1996-10-30 | 1998-05-06 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| ATE427362T1 (de) | 1999-02-10 | 2009-04-15 | Serono Genetics Inst Sa | Polymorphe marker des lsr-gens |
| CA2366072C (en) | 1999-03-08 | 2007-07-10 | Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. | Prrsv vaccines |
| ES2348159T3 (es) | 1999-04-22 | 2010-11-30 | United States Department Of Agriculture | Vacuna contra el sindrome respiratorio y reproductivo porcino basada en el aislado ja-142. |
| SG83740A1 (en) * | 1999-08-10 | 2001-10-16 | Inst Of Molecular Agrobiology | An attenuated porcine reproductive and respiratory syndrome virus strain and methods of use |
| US7338787B2 (en) | 2000-01-14 | 2008-03-04 | Serono Genetics Institute S.A. | Nucleic acids encoding OBG3 globular head and uses thereof |
| EP1156111A1 (en) * | 2000-05-19 | 2001-11-21 | Stichting Dienst Landbouwkundig Onderzoek | Chimeric arterivirus-like particles |
| BR0116018A (pt) | 2000-12-07 | 2005-12-13 | Syngenta Ltd | Enzima de hidróxi fenil piruvato dioxigenase (hppd) resistente especìfica para o inibidor de tricetona, plantas resistentes a herbicida, métodos para selecionar um polinucleotìdeo que codifica uma enzima de hppd resistente à tricetona, para selecionar polinucleotìdeos que compreendem uma região que codifica uma enzima de hppd resistente especìfica para tricetona e para o ácido sincárpico, e para fornecer uma planta que seja tolerante aos herbicidas inibidores da hppd, planta inteira fértil morfologicamente normal, uso do polinucleotìdeo selecionável, método para controlar seletivamente ervas daninhas em um local compreendendo plantas de safra e ervas daninhas, polinucleotìdeo, e, células vegetais |
| AU2002309486A1 (en) * | 2001-01-30 | 2002-10-15 | The Lauridsen Group, Incorporated | Methods and compositions for modulating the immune system of animals |
| KR20050040172A (ko) * | 2003-10-27 | 2005-05-03 | 주식회사 중앙백신연구소 | 돼지 생식기호흡기 증후군 바이러스 불활화 백신의 제조방법 |
| RU2007101725A (ru) * | 2004-06-18 | 2008-07-27 | Риджентс Оф Дзе Юниверсити Оф Миннесота (Us) | Идентификация инфицированных вирусом и вакцинированных вирусом организмов |
| US7632636B2 (en) | 2004-09-21 | 2009-12-15 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome isolates and methods of use |
| DE602005023342D1 (en) * | 2004-11-19 | 2010-10-14 | Intervet Int Bv | S (porcine reproductive und respiratory syndrome) von schweinen |
| CA2894069C (en) | 2005-06-24 | 2019-02-26 | Regents Of The University Of Minnesota | Prrs viruses, infectious clones, mutants thereof, and methods of use |
| EP2275132B1 (en) | 2005-12-29 | 2021-03-03 | Boehringer Ingelheim Animal Health USA Inc. | Multivalent PCV2 immunogenic compositions and methods of producing them |
| CN100523177C (zh) * | 2007-01-09 | 2009-08-05 | 中国农业科学院哈尔滨兽医研究所 | 猪繁殖与呼吸综合症病毒弱毒疫苗株及其应用 |
| RU2561595C2 (ru) * | 2008-08-25 | 2015-08-27 | Бёрингер Ингельхайм Ветмедика, Инк. | Вакцина против высокопатогенного репродуктивно-респираторного синдрома свиней (hp prrs) |
| TWI627281B (zh) | 2009-09-02 | 2018-06-21 | 百靈佳殷格翰家畜藥品公司 | 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物 |
| EA038012B1 (ru) | 2011-02-17 | 2021-06-23 | Бёрингер Ингельхайм Ветмедика Гмбх | Композиция на основе нового штамма prrsv или его белков, продукт, их применение, вирус prrsv, выделенная нк и рекомбинантный вектор экспрессии для получения этого вируса |
| SG192821A1 (en) | 2011-02-17 | 2013-09-30 | Boehringer Ingelheim Vetmed | Commercial scale process for production of prrsv |
| KR101281361B1 (ko) * | 2011-07-18 | 2013-07-02 | 서울대학교산학협력단 | 북미형 돼지 생식기 호흡기 증후군 바이러스 예방 백신 조성물 및 이를 포함하는 혼합백신 조성물 |
| US9187731B2 (en) | 2011-07-29 | 2015-11-17 | Boehringer Ingelheim Vetmedica Gmbh | PRRS virus inducing type I interferon in susceptible cells |
| EP2737058A1 (en) | 2011-07-29 | 2014-06-04 | Boehringer Ingelheim Vetmedica GmbH | INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF |
| JP6386999B2 (ja) * | 2012-05-17 | 2018-09-05 | ゾエティス・エルエルシー | ブタ生殖および呼吸症候群（ｐｒｒｓ）ウイルスに対する離乳前の効果的なワクチン接種 |
| MX366051B (es) | 2012-12-07 | 2019-06-26 | Univ Illinois | Composiciones del virus del síndrome reproductor y respiratorio de porcino y sus usos. |
| US9579373B2 (en) | 2013-03-15 | 2017-02-28 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use |
| JP6886291B2 (ja) | 2013-12-20 | 2021-06-16 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーＢｏｅｈｒｉｎｇｅｒ Ｉｎｇｅｌｈｅｉｍ Ｖｅｔｍｅｄｉｃａ ＧｍｂＨ | ＰＲＲＳウイルス変異株、ヨーロッパ型ＰＲＲＳウイルスｃＤＮＡクローンおよびそれらの使用 |
| US10660952B2 (en) | 2016-11-03 | 2020-05-26 | Boehringer Ingelheim Vetmedica Gmbh | Vaccine against porcine parvovirus and porcine reproductive and respiratory syndrome virus and methods of production thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2103460C (en) * | 1991-06-06 | 2000-09-26 | Gert Wensvoort | Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits |
| KR0138092B1 (ko) * | 1991-08-26 | 1998-04-30 | 제임스 씨. 데세사레 | 미확인(Mystery) 돼지 질병 관련 바이러스제 |
| KR100241221B1 (ko) * | 1991-08-26 | 2000-03-02 | 에드워드 콜린스 제임스 | 돼지 불임 및 호흡기계 중후백신 및 그의 진단법 |
| AU2684792A (en) * | 1991-10-14 | 1993-05-21 | Akzo Nobel N.V. | Porcine reproductive respiratory syndrome vaccine and diagnostic |
| ATE197314T1 (de) * | 1993-02-08 | 2000-11-15 | Bayer Ag | Verfahren zum vermehren des das reproduktions- und atemwegs-syndrom verursachenden schweinevirus und dessen verwendung als impfstoff. |
| EP0676467B1 (en) * | 1994-04-11 | 2001-10-04 | Akzo Nobel N.V. | European vaccine strains of the porcine reproductive respiratory syndrome virus (PRRSV) |
-
1996
- 1996-01-25 ES ES09600168A patent/ES2102971B1/es not_active Expired - Fee Related
- 1996-04-12 UA UA97105158A patent/UA68326C2/uk unknown
- 1996-12-04 HU HU9801124A patent/HUP9801124A3/hu unknown
- 1996-12-04 US US08/930,330 patent/US6001370A/en not_active Expired - Fee Related
- 1996-12-04 PL PL96322455A patent/PL185841B1/pl not_active IP Right Cessation
- 1996-12-04 EP EP96940665A patent/EP0835929A1/en not_active Withdrawn
- 1996-12-04 CA CA002216436A patent/CA2216436A1/en not_active Abandoned
- 1996-12-04 KR KR1019970706672A patent/KR19980703268A/ko active IP Right Grant
- 1996-12-04 WO PCT/ES1996/000234 patent/WO1997027288A1/es not_active Application Discontinuation
- 1996-12-04 JP JP9526571A patent/JP3068204B2/ja not_active Expired - Lifetime
- 1996-12-04 CZ CZ19973377A patent/CZ286766B6/cs not_active IP Right Cessation
- 1996-12-04 CN CN96194133A patent/CN1185806A/zh active Pending
- 1996-12-04 BR BR9604888A patent/BR9604888A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| MX9707302A (es) | 1998-06-30 |
| JPH10507372A (ja) | 1998-07-21 |
| CN1185806A (zh) | 1998-06-24 |
| PL322455A1 (en) | 1998-02-02 |
| HUP9801124A3 (en) | 1999-09-28 |
| ES2102971A1 (es) | 1997-08-01 |
| CZ286766B6 (en) | 2000-06-14 |
| WO1997027288A1 (es) | 1997-07-31 |
| JP3068204B2 (ja) | 2000-07-24 |
| KR19980703268A (ko) | 1998-10-15 |
| CZ337797A3 (cs) | 1998-03-18 |
| EP0835929A1 (en) | 1998-04-15 |
| US6001370A (en) | 1999-12-14 |
| ES2102971B1 (es) | 1998-03-01 |
| BR9604888A (pt) | 1998-12-15 |
| HUP9801124A2 (hu) | 1998-08-28 |
| PL185841B1 (pl) | 2003-08-29 |
| CA2216436A1 (en) | 1997-07-31 |
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