UA61879C2 - Piperazine-2,5-dione derivatives as resistance modulators to many preparations - Google Patents

Piperazine-2,5-dione derivatives as resistance modulators to many preparations Download PDF

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Publication number
UA61879C2
UA61879C2 UA97062956A UA97062956A UA61879C2 UA 61879 C2 UA61879 C2 UA 61879C2 UA 97062956 A UA97062956 A UA 97062956A UA 97062956 A UA97062956 A UA 97062956A UA 61879 C2 UA61879 C2 UA 61879C2
Authority
UA
Ukraine
Prior art keywords
methyl
benzylidene
dioxo
methylbenzamide
piperazinylidene
Prior art date
Application number
UA97062956A
Other languages
English (en)
Ukrainian (uk)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of UA61879C2 publication Critical patent/UA61879C2/uk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Electron Tubes For Measurement (AREA)
UA97062956A 1994-12-23 1995-12-22 Piperazine-2,5-dione derivatives as resistance modulators to many preparations UA61879C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9426090.8A GB9426090D0 (en) 1994-12-23 1994-12-23 Pharmaceutical compounds
PCT/GB1995/003029 WO1996020180A1 (en) 1994-12-23 1995-12-22 Piperazine-2,5-dione derivatives as modulators of multidrug resistance

Publications (1)

Publication Number Publication Date
UA61879C2 true UA61879C2 (en) 2003-12-15

Family

ID=10766502

Family Applications (1)

Application Number Title Priority Date Filing Date
UA97062956A UA61879C2 (en) 1994-12-23 1995-12-22 Piperazine-2,5-dione derivatives as resistance modulators to many preparations

Country Status (27)

Country Link
US (1) US5935955A (cs)
EP (1) EP0799210B1 (cs)
JP (1) JPH10511385A (cs)
KR (1) KR100412167B1 (cs)
CN (1) CN1108294C (cs)
AT (1) ATE204569T1 (cs)
AU (1) AU700891B2 (cs)
BG (1) BG63305B1 (cs)
BR (1) BR9510429A (cs)
CA (1) CA2207548A1 (cs)
CZ (1) CZ288935B6 (cs)
DE (1) DE69522342T2 (cs)
DK (1) DK0799210T3 (cs)
ES (1) ES2160726T3 (cs)
FI (1) FI972661L (cs)
GB (2) GB9426090D0 (cs)
HU (1) HUT77740A (cs)
IL (1) IL116526A (cs)
MY (1) MY131762A (cs)
NO (1) NO308532B1 (cs)
NZ (1) NZ297849A (cs)
PL (1) PL186851B1 (cs)
PT (1) PT799210E (cs)
SK (1) SK283385B6 (cs)
UA (1) UA61879C2 (cs)
WO (1) WO1996020180A1 (cs)
ZA (1) ZA9510908B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9708805D0 (en) 1997-05-01 1997-06-25 Smithkline Beecham Plc Compounds
GB9810876D0 (en) 1998-05-20 1998-07-22 Smithkline Beecham Plc Compounds
SK4782001A3 (en) 1998-10-08 2001-11-06 Smithkline Beecham Plc Tetrahydrobenzazepine derivatives useful as modulators of dopamine d3 receptors (antipsychotic agents)
EP1210093A4 (en) * 1999-09-03 2005-01-12 Polytherics Ltd DEGRADABLE POLYMERS
US6828412B1 (en) * 1999-09-03 2004-12-07 School Of Pharmacy, University Of London Degradable polymers
EP2266607A3 (en) 1999-10-01 2011-04-20 Immunogen, Inc. Immunoconjugates for treating cancer
US7220414B2 (en) 2000-09-06 2007-05-22 A.P. Pharma, Inc. Degradable polyacetal polymers
US6693099B2 (en) 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
US6376514B1 (en) 2000-10-17 2002-04-23 The Procter & Gamble Co. Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof
JP2005508990A (ja) * 2001-11-07 2005-04-07 ファルマシア・コーポレーション 真核細胞におけるポリアミドの取込みおよび核蓄積を促進する方法
US8710062B2 (en) * 2011-03-11 2014-04-29 Taipei Medical University Piperazinedione compounds
CN103396372B (zh) * 2013-08-09 2015-05-20 中国科学院南海海洋研究所 一类2,5-二酮哌嗪衍生物及其制备方法和在制备抗海洋污损生物防除剂中的应用
BR112021012639A2 (pt) * 2018-12-27 2021-09-28 Holosmedic Novo composto e composição farmacêutica compreendendo o mesmo para intensificar atividade anticâncer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2103479T3 (es) * 1992-07-10 1997-09-16 Glaxo Lab Sa Derivados de anilida.
GB9217331D0 (en) * 1992-08-14 1992-09-30 Xenova Ltd Pharmaceutical compounds
AU664920B2 (en) * 1992-08-14 1995-12-07 Asahi Breweries, Ltd. Peptide having allergenicity
GB9402807D0 (en) * 1994-02-14 1994-04-06 Xenova Ltd Pharmaceutical compounds
GB9410387D0 (en) * 1994-05-24 1994-07-13 Xenova Ltd Pharmaceutical compounds

Also Published As

Publication number Publication date
AU700891B2 (en) 1999-01-14
BG101601A (bg) 1998-02-27
GB2311780B (en) 1999-03-03
ZA9510908B (en) 1996-06-24
DK0799210T3 (da) 2001-10-01
EP0799210B1 (en) 2001-08-22
GB9426090D0 (en) 1995-02-22
ES2160726T3 (es) 2001-11-16
JPH10511385A (ja) 1998-11-04
ATE204569T1 (de) 2001-09-15
IL116526A0 (en) 1996-03-31
SK283385B6 (sk) 2003-06-03
PL186851B1 (pl) 2004-03-31
FI972661A0 (fi) 1997-06-19
US5935955A (en) 1999-08-10
WO1996020180A1 (en) 1996-07-04
KR100412167B1 (ko) 2004-05-27
NO308532B1 (no) 2000-09-25
PL320915A1 (en) 1997-11-10
SK83597A3 (en) 1998-04-08
CZ288935B6 (cs) 2001-09-12
NO972938D0 (no) 1997-06-23
FI972661A7 (fi) 1997-08-22
NZ297849A (en) 1999-04-29
NO972938L (no) 1997-06-23
FI972661L (fi) 1997-08-22
MY131762A (en) 2007-08-30
AU4310296A (en) 1996-07-19
CZ190297A3 (cs) 1998-01-14
CN1176637A (zh) 1998-03-18
CA2207548A1 (en) 1996-07-04
GB2311780A (en) 1997-10-08
HK1001974A1 (en) 1998-07-24
EP0799210A1 (en) 1997-10-08
IL116526A (en) 1999-11-30
DE69522342T2 (de) 2002-01-03
GB9712179D0 (en) 1997-08-13
CN1108294C (zh) 2003-05-14
BR9510429A (pt) 1998-07-07
DE69522342D1 (de) 2001-09-27
HUT77740A (hu) 1998-07-28
BG63305B1 (bg) 2001-09-28
PT799210E (pt) 2002-01-30

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