NO308532B1 - Farmasøytiske piperazinforbindelser - Google Patents

Farmasøytiske piperazinforbindelser

Info

Publication number
NO308532B1
NO308532B1 NO972938A NO972938A NO308532B1 NO 308532 B1 NO308532 B1 NO 308532B1 NO 972938 A NO972938 A NO 972938A NO 972938 A NO972938 A NO 972938A NO 308532 B1 NO308532 B1 NO 308532B1
Authority
NO
Norway
Prior art keywords
pct
formula
group
piperazine compounds
sec
Prior art date
Application number
NO972938A
Other languages
English (en)
Norwegian (no)
Other versions
NO972938D0 (no
NO972938L (no
Inventor
Philip Anthony Ashworth
Sukhjit Hunjan
Ian Andrew Pretswell
Hamish Ryder
Stephen James Brocchini
Original Assignee
Xenova Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenova Ltd filed Critical Xenova Ltd
Publication of NO972938D0 publication Critical patent/NO972938D0/no
Publication of NO972938L publication Critical patent/NO972938L/no
Publication of NO308532B1 publication Critical patent/NO308532B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Electron Tubes For Measurement (AREA)
NO972938A 1994-12-23 1997-06-23 Farmasøytiske piperazinforbindelser NO308532B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9426090.8A GB9426090D0 (en) 1994-12-23 1994-12-23 Pharmaceutical compounds
PCT/GB1995/003029 WO1996020180A1 (en) 1994-12-23 1995-12-22 Piperazine-2,5-dione derivatives as modulators of multidrug resistance

Publications (3)

Publication Number Publication Date
NO972938D0 NO972938D0 (no) 1997-06-23
NO972938L NO972938L (no) 1997-06-23
NO308532B1 true NO308532B1 (no) 2000-09-25

Family

ID=10766502

Family Applications (1)

Application Number Title Priority Date Filing Date
NO972938A NO308532B1 (no) 1994-12-23 1997-06-23 Farmasøytiske piperazinforbindelser

Country Status (27)

Country Link
US (1) US5935955A (cs)
EP (1) EP0799210B1 (cs)
JP (1) JPH10511385A (cs)
KR (1) KR100412167B1 (cs)
CN (1) CN1108294C (cs)
AT (1) ATE204569T1 (cs)
AU (1) AU700891B2 (cs)
BG (1) BG63305B1 (cs)
BR (1) BR9510429A (cs)
CA (1) CA2207548A1 (cs)
CZ (1) CZ288935B6 (cs)
DE (1) DE69522342T2 (cs)
DK (1) DK0799210T3 (cs)
ES (1) ES2160726T3 (cs)
FI (1) FI972661L (cs)
GB (2) GB9426090D0 (cs)
HU (1) HUT77740A (cs)
IL (1) IL116526A (cs)
MY (1) MY131762A (cs)
NO (1) NO308532B1 (cs)
NZ (1) NZ297849A (cs)
PL (1) PL186851B1 (cs)
PT (1) PT799210E (cs)
SK (1) SK283385B6 (cs)
UA (1) UA61879C2 (cs)
WO (1) WO1996020180A1 (cs)
ZA (1) ZA9510908B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9708805D0 (en) 1997-05-01 1997-06-25 Smithkline Beecham Plc Compounds
GB9810876D0 (en) 1998-05-20 1998-07-22 Smithkline Beecham Plc Compounds
SK4782001A3 (en) 1998-10-08 2001-11-06 Smithkline Beecham Plc Tetrahydrobenzazepine derivatives useful as modulators of dopamine d3 receptors (antipsychotic agents)
EP1210093A4 (en) * 1999-09-03 2005-01-12 Polytherics Ltd DEGRADABLE POLYMERS
US6828412B1 (en) * 1999-09-03 2004-12-07 School Of Pharmacy, University Of London Degradable polymers
EP2266607A3 (en) 1999-10-01 2011-04-20 Immunogen, Inc. Immunoconjugates for treating cancer
US7220414B2 (en) 2000-09-06 2007-05-22 A.P. Pharma, Inc. Degradable polyacetal polymers
US6693099B2 (en) 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
US6376514B1 (en) 2000-10-17 2002-04-23 The Procter & Gamble Co. Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof
JP2005508990A (ja) * 2001-11-07 2005-04-07 ファルマシア・コーポレーション 真核細胞におけるポリアミドの取込みおよび核蓄積を促進する方法
US8710062B2 (en) * 2011-03-11 2014-04-29 Taipei Medical University Piperazinedione compounds
CN103396372B (zh) * 2013-08-09 2015-05-20 中国科学院南海海洋研究所 一类2,5-二酮哌嗪衍生物及其制备方法和在制备抗海洋污损生物防除剂中的应用
BR112021012639A2 (pt) * 2018-12-27 2021-09-28 Holosmedic Novo composto e composição farmacêutica compreendendo o mesmo para intensificar atividade anticâncer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2103479T3 (es) * 1992-07-10 1997-09-16 Glaxo Lab Sa Derivados de anilida.
GB9217331D0 (en) * 1992-08-14 1992-09-30 Xenova Ltd Pharmaceutical compounds
AU664920B2 (en) * 1992-08-14 1995-12-07 Asahi Breweries, Ltd. Peptide having allergenicity
GB9402807D0 (en) * 1994-02-14 1994-04-06 Xenova Ltd Pharmaceutical compounds
GB9410387D0 (en) * 1994-05-24 1994-07-13 Xenova Ltd Pharmaceutical compounds

Also Published As

Publication number Publication date
AU700891B2 (en) 1999-01-14
BG101601A (bg) 1998-02-27
GB2311780B (en) 1999-03-03
ZA9510908B (en) 1996-06-24
DK0799210T3 (da) 2001-10-01
EP0799210B1 (en) 2001-08-22
GB9426090D0 (en) 1995-02-22
ES2160726T3 (es) 2001-11-16
JPH10511385A (ja) 1998-11-04
ATE204569T1 (de) 2001-09-15
IL116526A0 (en) 1996-03-31
SK283385B6 (sk) 2003-06-03
PL186851B1 (pl) 2004-03-31
FI972661A0 (fi) 1997-06-19
US5935955A (en) 1999-08-10
WO1996020180A1 (en) 1996-07-04
UA61879C2 (en) 2003-12-15
KR100412167B1 (ko) 2004-05-27
PL320915A1 (en) 1997-11-10
SK83597A3 (en) 1998-04-08
CZ288935B6 (cs) 2001-09-12
NO972938D0 (no) 1997-06-23
FI972661A7 (fi) 1997-08-22
NZ297849A (en) 1999-04-29
NO972938L (no) 1997-06-23
FI972661L (fi) 1997-08-22
MY131762A (en) 2007-08-30
AU4310296A (en) 1996-07-19
CZ190297A3 (cs) 1998-01-14
CN1176637A (zh) 1998-03-18
CA2207548A1 (en) 1996-07-04
GB2311780A (en) 1997-10-08
HK1001974A1 (en) 1998-07-24
EP0799210A1 (en) 1997-10-08
IL116526A (en) 1999-11-30
DE69522342T2 (de) 2002-01-03
GB9712179D0 (en) 1997-08-13
CN1108294C (zh) 2003-05-14
BR9510429A (pt) 1998-07-07
DE69522342D1 (de) 2001-09-27
HUT77740A (hu) 1998-07-28
BG63305B1 (bg) 2001-09-28
PT799210E (pt) 2002-01-30

Similar Documents

Publication Publication Date Title
DK0736018T3 (da) 4,5-Diaryloxazolderivater
ATE188472T1 (de) 4-arylmethyloxymethyl piperidine als tachykinin antagonisten
ATE206611T1 (de) Verwendung von mangiferin oder seinen derivaten zur kosmetischen anwendung
MX9800577A (es) Derivados de 4,5-diaril oxazol.
NO972938L (no) Farmasöytiske piperazinforbindelser
DK0677046T3 (da) Piperazinderivater som 5-HT-antagonister.
FR2712591B1 (fr) Nouvelles arylpipérazines dérivées d'indole, leur préparation et leur utilisation thérapeutique.
ES2098023T3 (es) Compuestos de estructura guanidinica y composiciones farmaceuticas que los contienen.
ATE172193T1 (de) Piperazinderivate
EP1130015A4 (en) PYRIDAZINONE DERIVATIVES
NO955328L (no) Pyridazinon-derivater
DE69719511D1 (de) Antivirale 2,4-pyrimidindion-derivate und verfahren zu ihrer herstellung
DK0777653T3 (da) Dihydropyridinderivater som bradykininantagonister
HRP20010885B1 (en) Ethanesulfonyl-piperidine derivatives
DK0775143T3 (da) 3-substituerede 3H-2,3-benzodiazepinderivater, deres fremstilling og anvendelse som lægdemidler
SE9603284D0 (sv) New compounds
ES2120039T3 (es) Nuevos acildipeptidos heterociclicos, procedimientos de preparacion y composiciones farmaceuticas que los contienen.

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees