UA123309C2 - Композиція для догляду за порожниною рота - Google Patents
Композиція для догляду за порожниною рота Download PDFInfo
- Publication number
- UA123309C2 UA123309C2 UAA201711190A UAA201711190A UA123309C2 UA 123309 C2 UA123309 C2 UA 123309C2 UA A201711190 A UAA201711190 A UA A201711190A UA A201711190 A UAA201711190 A UA A201711190A UA 123309 C2 UA123309 C2 UA 123309C2
- Authority
- UA
- Ukraine
- Prior art keywords
- salt
- calcium
- dicarboxylic acid
- phosphate
- dentinal tubules
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 200
- 210000005239 tubule Anatomy 0.000 claims abstract description 117
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 claims abstract description 100
- 201000002170 dentin sensitivity Diseases 0.000 claims abstract description 78
- 230000036347 tooth sensitivity Effects 0.000 claims abstract description 78
- 150000003839 salts Chemical class 0.000 claims abstract description 60
- 159000000007 calcium salts Chemical class 0.000 claims abstract description 48
- 239000004480 active ingredient Substances 0.000 claims description 31
- 229910019142 PO4 Inorganic materials 0.000 claims description 29
- 239000010452 phosphate Substances 0.000 claims description 29
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims description 29
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical group [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 28
- 125000004432 carbon atom Chemical group C* 0.000 claims description 20
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims description 18
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 14
- 235000010216 calcium carbonate Nutrition 0.000 claims description 14
- 210000004268 dentin Anatomy 0.000 claims description 12
- WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical compound OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 claims description 11
- 239000001488 sodium phosphate Substances 0.000 claims description 11
- LWIHDJKSTIGBAC-UHFFFAOYSA-K potassium phosphate Substances [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 claims description 10
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 claims description 9
- 235000019700 dicalcium phosphate Nutrition 0.000 claims description 7
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims description 6
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 claims description 6
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims description 6
- BDJRBEYXGGNYIS-UHFFFAOYSA-N nonanedioic acid Chemical compound OC(=O)CCCCCCCC(O)=O BDJRBEYXGGNYIS-UHFFFAOYSA-N 0.000 claims description 6
- 235000006408 oxalic acid Nutrition 0.000 claims description 6
- WLJVNTCWHIRURA-UHFFFAOYSA-N pimelic acid Chemical compound OC(=O)CCCCCC(O)=O WLJVNTCWHIRURA-UHFFFAOYSA-N 0.000 claims description 6
- TYFQFVWCELRYAO-UHFFFAOYSA-N suberic acid Chemical compound OC(=O)CCCCCCC(O)=O TYFQFVWCELRYAO-UHFFFAOYSA-N 0.000 claims description 6
- RTBFRGCFXZNCOE-UHFFFAOYSA-N 1-methylsulfonylpiperidin-4-one Chemical compound CS(=O)(=O)N1CCC(=O)CC1 RTBFRGCFXZNCOE-UHFFFAOYSA-N 0.000 claims description 5
- 239000001361 adipic acid Substances 0.000 claims description 5
- 235000011037 adipic acid Nutrition 0.000 claims description 5
- JFCQEDHGNNZCLN-UHFFFAOYSA-N anhydrous glutaric acid Natural products OC(=O)CCCC(O)=O JFCQEDHGNNZCLN-UHFFFAOYSA-N 0.000 claims description 5
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 claims description 5
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 claims description 4
- 229910000397 disodium phosphate Inorganic materials 0.000 claims description 4
- 235000019800 disodium phosphate Nutrition 0.000 claims description 4
- 239000004151 Calcium iodate Substances 0.000 claims description 3
- WUKWITHWXAAZEY-UHFFFAOYSA-L calcium difluoride Chemical compound [F-].[F-].[Ca+2] WUKWITHWXAAZEY-UHFFFAOYSA-L 0.000 claims description 3
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims description 3
- 229910001634 calcium fluoride Inorganic materials 0.000 claims description 3
- 239000000920 calcium hydroxide Substances 0.000 claims description 3
- 229910001861 calcium hydroxide Inorganic materials 0.000 claims description 3
- UHWJJLGTKIWIJO-UHFFFAOYSA-L calcium iodate Chemical compound [Ca+2].[O-]I(=O)=O.[O-]I(=O)=O UHWJJLGTKIWIJO-UHFFFAOYSA-L 0.000 claims description 3
- 235000019390 calcium iodate Nutrition 0.000 claims description 3
- GBAOBIBJACZTNA-UHFFFAOYSA-L calcium sulfite Chemical compound [Ca+2].[O-]S([O-])=O GBAOBIBJACZTNA-UHFFFAOYSA-L 0.000 claims description 3
- 235000011132 calcium sulphate Nutrition 0.000 claims description 3
- 235000010261 calcium sulphite Nutrition 0.000 claims description 3
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 claims description 2
- 235000019797 dipotassium phosphate Nutrition 0.000 claims description 2
- 229910000396 dipotassium phosphate Inorganic materials 0.000 claims description 2
- 229910000402 monopotassium phosphate Inorganic materials 0.000 claims description 2
- 235000019796 monopotassium phosphate Nutrition 0.000 claims description 2
- 229910000403 monosodium phosphate Inorganic materials 0.000 claims description 2
- 235000019799 monosodium phosphate Nutrition 0.000 claims description 2
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 claims description 2
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical group [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 claims description 2
- 229910000404 tripotassium phosphate Inorganic materials 0.000 claims description 2
- 235000019798 tripotassium phosphate Nutrition 0.000 claims description 2
- 229910000406 trisodium phosphate Inorganic materials 0.000 claims description 2
- 235000019801 trisodium phosphate Nutrition 0.000 claims description 2
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 claims 2
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- 208000024891 symptom Diseases 0.000 abstract description 59
- 230000000694 effects Effects 0.000 abstract description 49
- 150000001879 copper Chemical class 0.000 abstract description 44
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- 239000011575 calcium Substances 0.000 abstract description 29
- 229910052791 calcium Inorganic materials 0.000 abstract description 29
- 210000000214 mouth Anatomy 0.000 abstract description 24
- 238000007789 sealing Methods 0.000 abstract description 7
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract description 3
- 230000001112 coagulating effect Effects 0.000 abstract 1
- 210000002531 dentinal fluid Anatomy 0.000 abstract 1
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- 229910052725 zinc Inorganic materials 0.000 abstract 1
- 239000011701 zinc Substances 0.000 abstract 1
- 230000000052 comparative effect Effects 0.000 description 33
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- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 150000001412 amines Chemical group 0.000 description 1
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- 230000000202 analgesic effect Effects 0.000 description 1
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- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
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- 229910052799 carbon Inorganic materials 0.000 description 1
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- 238000006243 chemical reaction Methods 0.000 description 1
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- 238000000576 coating method Methods 0.000 description 1
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- 235000009508 confectionery Nutrition 0.000 description 1
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- 238000002474 experimental method Methods 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 229940091249 fluoride supplement Drugs 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 150000002440 hydroxy compounds Chemical group 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 229920003063 hydroxymethyl cellulose Polymers 0.000 description 1
- 229940031574 hydroxymethyl cellulose Drugs 0.000 description 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 description 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 1
- 150000002466 imines Chemical group 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000005923 long-lasting effect Effects 0.000 description 1
- 239000001683 mentha spicata herb oil Substances 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 229940074371 monofluorophosphate Drugs 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000005416 organic matter Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000001991 pathophysiological effect Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 201000001245 periodontitis Diseases 0.000 description 1
- 239000002798 polar solvent Substances 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920000128 polypyrrole Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 229910001414 potassium ion Inorganic materials 0.000 description 1
- 235000010333 potassium nitrate Nutrition 0.000 description 1
- 239000004323 potassium nitrate Substances 0.000 description 1
- 229910000160 potassium phosphate Inorganic materials 0.000 description 1
- 235000011009 potassium phosphates Nutrition 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000006920 protein precipitation Effects 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Chemical group COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- HELHAJAZNSDZJO-OLXYHTOASA-L sodium L-tartrate Chemical compound [Na+].[Na+].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O HELHAJAZNSDZJO-OLXYHTOASA-L 0.000 description 1
- 229960003885 sodium benzoate Drugs 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 229910001415 sodium ion Inorganic materials 0.000 description 1
- 229940074404 sodium succinate Drugs 0.000 description 1
- ZDQYSKICYIVCPN-UHFFFAOYSA-L sodium succinate (anhydrous) Chemical compound [Na+].[Na+].[O-]C(=O)CCC([O-])=O ZDQYSKICYIVCPN-UHFFFAOYSA-L 0.000 description 1
- 239000001433 sodium tartrate Substances 0.000 description 1
- 229960002167 sodium tartrate Drugs 0.000 description 1
- 235000011004 sodium tartrates Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 235000019721 spearmint oil Nutrition 0.000 description 1
- 235000021259 spicy food Nutrition 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000003760 tallow Substances 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000007852 tooth bleaching agent Substances 0.000 description 1
- 210000004210 tooth component Anatomy 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/362—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20150054519 | 2015-04-17 | ||
| KR1020150184839A KR102076268B1 (ko) | 2015-04-17 | 2015-12-23 | 구강용 조성물 |
| KR1020160045681A KR102095945B1 (ko) | 2015-04-17 | 2016-04-14 | 구강용 조성물 |
| KR1020160045670A KR102045423B1 (ko) | 2015-04-17 | 2016-04-14 | 구강용 조성물 |
| PCT/KR2016/003945 WO2016167600A1 (ko) | 2015-04-17 | 2016-04-15 | 구강용 조성물 |
Publications (1)
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|---|---|
| UA123309C2 true UA123309C2 (uk) | 2021-03-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201711190A UA123309C2 (uk) | 2015-04-17 | 2016-04-15 | Композиція для догляду за порожниною рота |
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| Country | Link |
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| US (1) | US11103441B2 (https=) |
| JP (1) | JP6906777B2 (https=) |
| KR (3) | KR102076268B1 (https=) |
| CN (1) | CN107530236B (https=) |
| RU (1) | RU2706731C2 (https=) |
| TW (1) | TWI741982B (https=) |
| UA (1) | UA123309C2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR102300090B1 (ko) * | 2016-03-10 | 2021-09-07 | 주식회사 엘지생활건강 | 자화지정 추출물을 포함하는 구강질환 예방 또는 치료용 조성물 |
| CN112822993B (zh) * | 2018-10-09 | 2024-01-26 | 狮王株式会社 | 牙齿的再矿化促进剂及含有其的液体口腔用组合物 |
| CN113226250A (zh) * | 2018-12-20 | 2021-08-06 | 高露洁-棕榄公司 | 口腔护理组合物 |
| CN113813197B (zh) * | 2021-10-29 | 2023-06-13 | 重庆登康口腔护理用品股份有限公司 | 一种提升抑菌活性组合物及其在口腔制品中的应用 |
| CN117990728B (zh) * | 2024-04-07 | 2024-07-19 | 北京大学口腔医学院 | 蛋白质变性封堵型牙齿脱敏剂的体外功效评价装置和方法 |
Family Cites Families (25)
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| JPH0629169B2 (ja) | 1984-12-28 | 1994-04-20 | ライオン株式会社 | 口腔用組成物 |
| JPH06145020A (ja) * | 1991-06-03 | 1994-05-24 | Shono Yasuo | 結晶生成性歯質前処理剤及び製造方法 |
| US5270031A (en) | 1991-12-20 | 1993-12-14 | Block Drug Company Inc. | Dentinal desensitizing compositions |
| EP0651652B1 (en) * | 1992-06-29 | 2000-02-09 | The University Of Melbourne | Treatment for sensitive teeth |
| JP2550909B2 (ja) * | 1994-03-22 | 1996-11-06 | ライオン株式会社 | 口腔用組成物 |
| CZ289893B6 (cs) | 1994-09-21 | 2002-04-17 | Unilever N. V. | Orální prostředek |
| ITFI980051A1 (it) * | 1998-03-06 | 1999-09-06 | Italmed Di Galli Giovanna E Pa | Composizione ad uso odontoiatrico per la desensibilizzazione della dentina esposta |
| JP2004059583A (ja) | 1998-09-24 | 2004-02-26 | Fujisawa Pharmaceut Co Ltd | クロモグリク酸ナトリウムを含有する洗眼液及び点鼻液 |
| US6485708B1 (en) * | 1999-05-13 | 2002-11-26 | Church & Dwight Co. Inc. | Products and methods for the remineralization and prevention of demineralization of teeth |
| US6685920B2 (en) * | 1999-11-12 | 2004-02-03 | The Procter & Gamble Company | Method of protecting teeth against erosion |
| JP2004059563A (ja) * | 2002-07-31 | 2004-02-26 | Lion Corp | 象牙質知覚過敏用口腔用組成物 |
| JP2006347987A (ja) * | 2005-06-17 | 2006-12-28 | Sunstar Inc | 口腔用組成物および口腔用組成物の泡立性を高める方法 |
| JP4697449B2 (ja) * | 2006-05-19 | 2011-06-08 | ライオン株式会社 | 歯牙美白用組成物 |
| JP2008184436A (ja) * | 2007-01-30 | 2008-08-14 | Sun Medical Co Ltd | 知覚過敏抑制性歯科用研磨材組成物 |
| ITFI20080034A1 (it) * | 2008-02-26 | 2009-08-27 | Italmed S R L | Composizione odontoiatrica per la desensibilizzazione disinfezione e protezione della dentina esposta. |
| US8211407B2 (en) | 2008-11-25 | 2012-07-03 | The Procter & Gamble Company | Method of making oral care compositions with fused silica slurries |
| US8603442B2 (en) * | 2009-08-03 | 2013-12-10 | Mcneil-Ppc, Inc. | Tooth sensitivity treatment compositions |
| RU2012136867A (ru) | 2010-01-29 | 2014-03-10 | Колгейт-Палмолив Компани | Продукт для ухода за полостью рта для ухода за чувствительной эмалью |
| JP5723001B2 (ja) | 2010-06-23 | 2015-05-27 | コルゲート・パーモリブ・カンパニーＣｏｌｇａｔｅ−Ｐａｌｍｏｌｉｖｅ Ｃｏｍｐａｎｙ | 治療用口腔用組成物 |
| US20130224270A1 (en) | 2010-10-27 | 2013-08-29 | Colgate-Palmolive Company | Oral Care Composition Comprising Arginine and Calcium Carbonate |
| KR101262293B1 (ko) | 2011-01-18 | 2013-05-08 | 주식회사 바이오알파 | 중성에서 안정한 고농도 인산칼슘 수용액의 제조방법 |
| PH12013502103A1 (en) * | 2011-04-18 | 2013-12-16 | Unilever Ip Holdings B V | Tooth remineralizing oral care compositions |
| KR101883753B1 (ko) * | 2011-11-04 | 2018-07-31 | (주)아모레퍼시픽 | 시린이 방지용 조성물 및 분사기 |
| KR101569348B1 (ko) | 2012-01-13 | 2015-11-27 | (주)아모레퍼시픽 | 시린이를 위한 구강용 조성물 |
| BR112015006955B1 (pt) * | 2012-10-12 | 2019-06-25 | Unilever N.V. | Composição para a higiene bucal, método para aprimorar a higiene bucal e processos para a fabricação da composição para a higiene bucal |
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2015
- 2015-12-23 KR KR1020150184839A patent/KR102076268B1/ko active Active
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2016
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- 2016-04-14 KR KR1020160045681A patent/KR102095945B1/ko active Active
- 2016-04-15 US US15/567,240 patent/US11103441B2/en active Active
- 2016-04-15 CN CN201680022090.1A patent/CN107530236B/zh active Active
- 2016-04-15 JP JP2017554452A patent/JP6906777B2/ja active Active
- 2016-04-15 UA UAA201711190A patent/UA123309C2/uk unknown
- 2016-04-15 TW TW105111871A patent/TWI741982B/zh active
- 2016-04-15 RU RU2017139874A patent/RU2706731C2/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| KR102076268B1 (ko) | 2020-02-11 |
| JP6906777B2 (ja) | 2021-07-21 |
| RU2017139874A (ru) | 2019-05-17 |
| RU2017139874A3 (https=) | 2019-07-24 |
| US11103441B2 (en) | 2021-08-31 |
| HK1248584A1 (zh) | 2018-10-19 |
| KR20160123975A (ko) | 2016-10-26 |
| CN107530236A (zh) | 2018-01-02 |
| US20180153789A1 (en) | 2018-06-07 |
| KR102095945B1 (ko) | 2020-04-01 |
| JP2018511644A (ja) | 2018-04-26 |
| KR102045423B1 (ko) | 2019-11-15 |
| CN107530236B (zh) | 2021-10-26 |
| TW201705934A (zh) | 2017-02-16 |
| RU2706731C2 (ru) | 2019-11-20 |
| KR20160124008A (ko) | 2016-10-26 |
| KR20160124009A (ko) | 2016-10-26 |
| TWI741982B (zh) | 2021-10-11 |
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