UA115964C2 - Інтерлейкін-13-зв'язувальний білок - Google Patents

Інтерлейкін-13-зв'язувальний білок

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Publication number
UA115964C2
UA115964C2 UAA201302560A UAA201302560A UA115964C2 UA 115964 C2 UA115964 C2 UA 115964C2 UA A201302560 A UAA201302560 A UA A201302560A UA A201302560 A UAA201302560 A UA A201302560A UA 115964 C2 UA115964 C2 UA 115964C2
Authority
UA
Ukraine
Prior art keywords
interlaykin
binding protein
binding
owner
antigen
Prior art date
Application number
UAA201302560A
Other languages
English (en)
Inventor
Ченбін Ву
Річард В. Діксон
Джонатан П. БЕЛК
Хуа Ін
Марія А. Арджиріаді
Керолін А. Кафф
Пол Р. Хінтон
Шанкар КУМАР
Террі Л. Мелім
Янь ЧЕНЬ
Original Assignee
Еббві Айрленд Анлімітед Компані
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Еббві Айрленд Анлімітед Компані filed Critical Еббві Айрленд Анлімітед Компані
Publication of UA115964C2 publication Critical patent/UA115964C2/uk

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
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    • A01H1/00—Processes for modifying genotypes ; Plants characterised by associated natural traits
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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Abstract

Винахід належить до рекомбінантного антитіла або його антигензв’язувального фрагмента, які зв’язують IL-13 людини, блокує зв’язування IL-13 з IL-13Rα1 і з IL-13Rα2, виділеної нуклеїнової кислоти, що кодує вказане антитіло, вектора, клітини-хазяїна, способу одержання, фармацевтичної композиції та способу лікування суб’єкта від розладу, при якому активність IL-13 є шкідливою.
UAA201302560A 2006-09-08 2007-09-07 Інтерлейкін-13-зв'язувальний білок UA115964C2 (uk)

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MX349810B (es) 2017-08-14
RU2605327C2 (ru) 2016-12-20
TW200831533A (en) 2008-08-01
MY161894A (en) 2017-05-15
KR101676269B1 (ko) 2016-11-15
EP3910065A1 (en) 2021-11-17
EP2064336B1 (en) 2017-12-27
KR20090058016A (ko) 2009-06-08
JP2010502224A (ja) 2010-01-28
WO2008127271A2 (en) 2008-10-23
BRPI0716438B1 (pt) 2022-01-25
LT3339445T (lt) 2020-10-26
RU2472807C2 (ru) 2013-01-20
KR101544108B1 (ko) 2015-08-13
TWI496790B (zh) 2015-08-21
MX2009002554A (es) 2009-03-20
CN101512008B (zh) 2015-04-01
EP3524685A1 (en) 2019-08-14
EP2064336A4 (en) 2010-03-17
EP3339445A1 (en) 2018-06-27
MY188368A (en) 2021-12-06
RU2012142311A (ru) 2014-04-10
SI3339445T1 (sl) 2020-12-31
PT3339445T (pt) 2020-09-01
CY1123752T1 (el) 2022-03-24
US20080171014A1 (en) 2008-07-17
CN104774266A (zh) 2015-07-15
ES2661032T3 (es) 2018-03-27
US9592293B2 (en) 2017-03-14
KR20150056666A (ko) 2015-05-26
US20170340737A1 (en) 2017-11-30
US10086076B2 (en) 2018-10-02
AU2007351514A1 (en) 2008-10-23
ZA200901526B (en) 2018-11-28
CN101512008A (zh) 2009-08-19
IL197213A (en) 2013-06-27
JP2014237671A (ja) 2014-12-18
US20190008966A1 (en) 2019-01-10
ES2902063T3 (es) 2022-03-24
IL245666B (en) 2018-08-30
KR101625961B1 (ko) 2016-05-31

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