SG11201507423YA - DUAL SPECIFIC BINDING PROTEINS DIRECTED AGAINST TNFα - Google Patents
DUAL SPECIFIC BINDING PROTEINS DIRECTED AGAINST TNFαInfo
- Publication number
- SG11201507423YA SG11201507423YA SG11201507423YA SG11201507423YA SG11201507423YA SG 11201507423Y A SG11201507423Y A SG 11201507423YA SG 11201507423Y A SG11201507423Y A SG 11201507423YA SG 11201507423Y A SG11201507423Y A SG 11201507423YA SG 11201507423Y A SG11201507423Y A SG 11201507423YA
- Authority
- SG
- Singapore
- Prior art keywords
- specific binding
- directed against
- binding proteins
- dual specific
- proteins directed
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/35—Valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US201361794964P | 2013-03-15 | 2013-03-15 | |
PCT/US2014/028646 WO2014144299A2 (en) | 2013-03-15 | 2014-03-14 | DUAL SPECIFIC BINDING PROTEINS DIRECTED AGAINST TNFα |
Publications (1)
Publication Number | Publication Date |
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SG11201507423YA true SG11201507423YA (en) | 2015-10-29 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201507423YA SG11201507423YA (en) | 2013-03-15 | 2014-03-14 | DUAL SPECIFIC BINDING PROTEINS DIRECTED AGAINST TNFα |
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US (1) | US20140271457A1 (en) |
EP (1) | EP2970457A2 (en) |
JP (1) | JP2016517277A (en) |
KR (1) | KR20150131360A (en) |
CN (1) | CN105209491A (en) |
AR (1) | AR095588A1 (en) |
AU (1) | AU2014227664A1 (en) |
BR (1) | BR112015023557A2 (en) |
CA (1) | CA2904407A1 (en) |
CL (1) | CL2015002743A1 (en) |
CR (1) | CR20150522A (en) |
EC (1) | ECSP15040888A (en) |
IL (1) | IL240915A0 (en) |
MX (1) | MX2015013170A (en) |
PE (1) | PE20151670A1 (en) |
PH (1) | PH12015502007A1 (en) |
RU (1) | RU2015143833A (en) |
SG (1) | SG11201507423YA (en) |
TW (1) | TW201446800A (en) |
UY (1) | UY35479A (en) |
WO (1) | WO2014144299A2 (en) |
ZA (1) | ZA201506582B (en) |
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MX2010013239A (en) | 2008-06-03 | 2011-02-24 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof. |
PE20121647A1 (en) | 2009-08-29 | 2012-12-31 | Abbvie Inc | THERAPEUTIC BINDING PROTEINS TO DLL4 |
WO2011109298A2 (en) | 2010-03-02 | 2011-09-09 | Abbott Laboratories | Therapeutic dll4 binding proteins |
TW201206473A (en) | 2010-08-03 | 2012-02-16 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
JP2013539364A (en) | 2010-08-26 | 2013-10-24 | アッヴィ・インコーポレイテッド | Dual variable domain immunoglobulins and uses thereof |
AU2012328921B2 (en) | 2011-10-24 | 2017-05-11 | Abbvie Inc. | Immunobinders directed against TNF |
MX2014008101A (en) | 2011-12-30 | 2014-09-25 | Abbvie Inc | Dual variable domain immunoglobulins against il-13 and/or il-17. |
TW201811825A (en) | 2012-11-01 | 2018-04-01 | 美商艾伯維有限公司 | Anti-VEGF/DLL4 dual variable domain immunoglobulins and uses thereof |
TW201512219A (en) | 2013-03-15 | 2015-04-01 | Abbvie Inc | Dual specific binding proteins directed against IL-1[beta] and/or IL-17 |
MX2016010030A (en) | 2014-02-02 | 2017-04-27 | Medimmune Ltd | Chimeric protein composed of ngf antagonist domain and a tnfa antagonist domain. |
AU2015213681B2 (en) | 2014-02-10 | 2020-03-12 | Respivant Sciences Gmbh | Mast cell stabilizers for lung disease treatment |
US9962363B2 (en) | 2014-02-10 | 2018-05-08 | Patara Pharma, LLC | Mast cell stabilizers treatment for systemic disorders |
UA123624C2 (en) | 2014-09-03 | 2021-05-05 | Бьорінґер Інґельхайм Інтернаціональ Ґмбх | Compound targeting il-23a and tnf-alpha and uses thereof |
WO2016094881A2 (en) | 2014-12-11 | 2016-06-16 | Abbvie Inc. | Lrp-8 binding proteins |
TW201710286A (en) | 2015-06-15 | 2017-03-16 | 艾伯維有限公司 | Binding proteins against VEGF, PDGF, and/or their receptors |
WO2017027402A1 (en) | 2015-08-07 | 2017-02-16 | Patara Pharma, LLC | Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders |
US10238625B2 (en) | 2015-08-07 | 2019-03-26 | Respivant Sciences Gmbh | Methods for the treatment of mast cell related disorders with mast cell stabilizers |
CN117069855A (en) | 2015-10-25 | 2023-11-17 | 赛诺菲 | Trispecific and/or trivalent binding proteins for the prevention or treatment of HIV infection |
GB201522394D0 (en) | 2015-12-18 | 2016-02-03 | Ucb Biopharma Sprl | Antibodies |
KR20240036142A (en) * | 2016-04-13 | 2024-03-19 | 사노피 | Trispecific and/or trivalent binding proteins |
KR20180134378A (en) | 2016-04-13 | 2018-12-18 | 사노피 | 3 specificity and / or trivalent binding protein |
JP2019528320A (en) | 2016-08-31 | 2019-10-10 | レシュピファント サイエンシス ゲゼルシャフト ミット ベシュレンクター ハフトゥングRespivant Sciences Gmbh | Cromolyn composition for the treatment of chronic cough due to idiopathic pulmonary fibrosis |
WO2018067341A1 (en) | 2016-10-07 | 2018-04-12 | Patara Pharma, LLC | Cromolyn compositions for treatment of pulmonary fibrosis |
CN107375904B (en) * | 2017-08-01 | 2020-11-27 | 无锡市人民医院 | Application of beta-arrestin 1 in preventing and treating pigmentary disorder skin diseases |
CA3078800A1 (en) | 2017-10-10 | 2019-04-18 | Sanofi | Anti-cd38 antibodies and methods of use |
WO2020076853A1 (en) | 2018-10-09 | 2020-04-16 | Sanofi | Trispecific anti-cd38, anti-cd28, and anti-cd3 binding proteins and methods of use for treating viral infection |
US11613576B2 (en) | 2019-04-09 | 2023-03-28 | Sanofi | Trispecific binding proteins, methods, and uses thereof |
KR102267495B1 (en) * | 2019-08-07 | 2021-06-22 | 연세대학교 산학협력단 | Polypeptide for targeting mitochondria and uses thereof |
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US5006309A (en) | 1988-04-22 | 1991-04-09 | Abbott Laboratories | Immunoassay device with liquid transfer between wells by washing |
US5089424A (en) | 1988-06-14 | 1992-02-18 | Abbott Laboratories | Method and apparatus for heterogeneous chemiluminescence assay |
US5063081A (en) | 1988-11-14 | 1991-11-05 | I-Stat Corporation | Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor |
CA2069530A1 (en) | 1991-06-03 | 1992-12-04 | Cass J. Grandone | Reagent pack for immunoassays |
BRPI9715219B8 (en) | 1996-02-09 | 2015-07-07 | Abbvie Biotechnology Ltd | Recombinant expression vector, and prokaryotic host cell. |
US6914128B1 (en) | 1999-03-25 | 2005-07-05 | Abbott Gmbh & Co. Kg | Human antibodies that bind human IL-12 and methods for producing |
KR20020093029A (en) | 2000-04-11 | 2002-12-12 | 제넨테크, 인크. | Multivalent Antibodies And Uses Therefor |
SK1152003A3 (en) | 2000-06-29 | 2003-07-01 | Abbott Lab | Dual specificity antibodies and methods of making and using |
US7419821B2 (en) | 2002-03-05 | 2008-09-02 | I-Stat Corporation | Apparatus and methods for analyte measurement and immunoassay |
EP1575499A2 (en) * | 2002-06-28 | 2005-09-21 | Centocor, Inc. | Mammalian epo mimetic ch1 deleted mimetibodies, compositions, methods and uses |
PT1523496E (en) | 2002-07-18 | 2011-09-29 | Merus B V | Recombinant production of mixtures of antibodies |
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US7682833B2 (en) | 2003-09-10 | 2010-03-23 | Abbott Point Of Care Inc. | Immunoassay device with improved sample closure |
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US7612181B2 (en) * | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
KR101544108B1 (en) * | 2006-09-08 | 2015-08-13 | 애브비 바하마스 리미티드 | -13 Interleukin-13 binding proteins |
WO2009091912A2 (en) | 2008-01-15 | 2009-07-23 | Abbott Laboratories | Improved mammalian expression vectors and uses thereof |
MX2010013239A (en) | 2008-06-03 | 2011-02-24 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof. |
MX2010014574A (en) * | 2008-07-08 | 2011-04-27 | Abbott Lab | Prostaglandin e2 dual variable domain immunoglobulins and uses thereof. |
SG171812A1 (en) * | 2008-12-04 | 2011-07-28 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
RU2012119756A (en) * | 2009-10-15 | 2013-11-20 | Эбботт Лэборетриз | IMMUNOGLOBULINS WITH TWO VARIABLE DOMAINS AND THEIR APPLICATION |
UY32979A (en) * | 2009-10-28 | 2011-02-28 | Abbott Lab | IMMUNOGLOBULINS WITH DUAL VARIABLE DOMAIN AND USES OF THE SAME |
TW201206473A (en) * | 2010-08-03 | 2012-02-16 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
RS20140202A1 (en) * | 2011-10-24 | 2014-10-31 | Abbvie Inc. | Biospecific immunibinders directed against tnf and il-17 |
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2014
- 2014-03-14 EP EP14721652.7A patent/EP2970457A2/en not_active Withdrawn
- 2014-03-14 WO PCT/US2014/028646 patent/WO2014144299A2/en active Application Filing
- 2014-03-14 BR BR112015023557A patent/BR112015023557A2/en not_active IP Right Cessation
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- 2014-03-14 SG SG11201507423YA patent/SG11201507423YA/en unknown
- 2014-03-14 MX MX2015013170A patent/MX2015013170A/en unknown
- 2014-03-14 US US14/211,596 patent/US20140271457A1/en not_active Abandoned
- 2014-03-14 RU RU2015143833A patent/RU2015143833A/en not_active Application Discontinuation
- 2014-03-14 KR KR1020157029888A patent/KR20150131360A/en not_active Application Discontinuation
- 2014-03-14 CA CA2904407A patent/CA2904407A1/en not_active Abandoned
- 2014-03-14 AU AU2014227664A patent/AU2014227664A1/en not_active Abandoned
- 2014-03-14 PE PE2015001934A patent/PE20151670A1/en not_active Application Discontinuation
- 2014-03-14 TW TW103109732A patent/TW201446800A/en unknown
- 2014-03-14 JP JP2016502858A patent/JP2016517277A/en active Pending
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- 2015-09-23 EC ECIEPI201540888A patent/ECSP15040888A/en unknown
- 2015-10-08 CR CR20150522A patent/CR20150522A/en unknown
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TW201446800A (en) | 2014-12-16 |
RU2015143833A (en) | 2017-04-21 |
EP2970457A2 (en) | 2016-01-20 |
PE20151670A1 (en) | 2015-12-12 |
CA2904407A1 (en) | 2014-09-18 |
WO2014144299A3 (en) | 2014-12-18 |
AU2014227664A8 (en) | 2015-10-15 |
BR112015023557A2 (en) | 2017-10-24 |
MX2015013170A (en) | 2016-07-26 |
AR095588A1 (en) | 2015-10-28 |
JP2016517277A (en) | 2016-06-16 |
ECSP15040888A (en) | 2015-11-30 |
UY35479A (en) | 2014-09-30 |
US20140271457A1 (en) | 2014-09-18 |
KR20150131360A (en) | 2015-11-24 |
CL2015002743A1 (en) | 2016-03-18 |
IL240915A0 (en) | 2015-10-29 |
AU2014227664A1 (en) | 2015-09-24 |
PH12015502007A1 (en) | 2016-01-11 |
ZA201506582B (en) | 2017-01-25 |
WO2014144299A2 (en) | 2014-09-18 |
CR20150522A (en) | 2016-01-12 |
CN105209491A (en) | 2015-12-30 |
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