UA11192A - Спосіб отримаhhя похідhих заміщеhого - Google Patents

Спосіб отримаhhя похідhих заміщеhого

Info

Publication number
UA11192A
UA11192A UA4355784A UA4355784A UA11192A UA 11192 A UA11192 A UA 11192A UA 4355784 A UA4355784 A UA 4355784A UA 4355784 A UA4355784 A UA 4355784A UA 11192 A UA11192 A UA 11192A
Authority
UA
Ukraine
Prior art keywords
obtaining derivative
obtaining
substitutes
derivative substitutes
derivatives
Prior art date
Application number
UA4355784A
Other languages
English (en)
Russian (ru)
Inventor
Герман Маргарета Реймакерс Альфонс
Жан Едгар Фрейн Едді
Людовікус Хубертус Ван Гелдер Іозефус
Гастон Вене Марк
Original Assignee
Фармасетіка H.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фармасетіка H.В. filed Critical Фармасетіка H.В.
Publication of UA11192A publication Critical patent/UA11192A/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
UA4355784A 1987-06-01 1988-05-20 Спосіб отримаhhя похідhих заміщеhого UA11192A (uk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5602187A 1987-06-01 1987-06-01

Publications (1)

Publication Number Publication Date
UA11192A true UA11192A (uk) 1996-12-25

Family

ID=22001654

Family Applications (1)

Application Number Title Priority Date Filing Date
UA4355784A UA11192A (uk) 1987-06-01 1988-05-20 Спосіб отримаhhя похідhих заміщеhого

Country Status (24)

Country Link
EP (1) EP0293978B1 (uk)
JP (1) JPH0662612B2 (uk)
KR (1) KR970000952B1 (uk)
CN (1) CN1022184C (uk)
AU (1) AU603446B2 (uk)
BG (2) BG50278A3 (uk)
CA (1) CA1307271C (uk)
CY (1) CY1866A (uk)
DE (1) DE3884055T2 (uk)
DK (1) DK175218B1 (uk)
ES (1) ES2059490T3 (uk)
FI (1) FI90078C (uk)
HK (1) HK114795A (uk)
HU (2) HU201056B (uk)
IE (1) IE61823B1 (uk)
IL (1) IL86551A (uk)
LT (1) LT3950B (uk)
LV (1) LV10452B (uk)
NO (1) NO169900C (uk)
NZ (1) NZ224714A (uk)
PT (1) PT87623B (uk)
RU (1) RU1838308C (uk)
UA (1) UA11192A (uk)
ZA (1) ZA883861B (uk)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5157046A (en) * 1988-11-29 1992-10-20 Janssen Pharmaceutica N.V. Method of treating epithelial disorders
CA2002859C (en) * 1988-11-29 1998-12-29 Jean P. F. Van Wauwe Method of treating epithelial disorders
GB8827820D0 (en) * 1988-11-29 1988-12-29 Janssen Pharmaceutica Nv (1h-azol-1-ylmethyl)substituted quinoline derivatives
EP0408509B1 (de) * 1989-07-14 1996-03-06 Ciba-Geigy Ag Substituierte Benzonitrile
CA2026792A1 (en) * 1989-11-01 1991-05-02 Michael N. Greco (6,7-dihydro-5h-pyrrolo[1,2-c]imidazol-5-yl)- and (5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl) substituted 1h-benzotriazole derivatives
US5066656A (en) * 1989-11-01 1991-11-19 Janssen Pharmaceutica N.V. Pharmacologically active (6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl)- and (5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl) substituted 1H-benzotriazole derivatives
NZ236440A (en) * 1989-12-15 1993-07-27 Merck & Co Inc Reversal of sexual phenotype in poultry using an inhibitor of steroid biotransformation and/or aromatase inhibitor, poultry produced by this process
AU7124691A (en) * 1990-02-27 1991-08-29 Ciba-Geigy Ag Benzofurans
DE4010797A1 (de) * 1990-04-04 1991-10-10 Hoechst Ag Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
EP0457716A1 (de) * 1990-04-20 1991-11-21 Ciba-Geigy Ag Naphthalinderivate
TW224461B (uk) * 1990-09-18 1994-06-01 Ciba Geigy Ag
US5162337A (en) * 1990-10-05 1992-11-10 Merck & Co., Inc. Animal growth promotion
TW210334B (uk) * 1990-12-12 1993-08-01 Ciba Geigy Ag
CH683151A5 (de) * 1991-04-24 1994-01-31 Ciba Geigy Ag Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus.
DE69230225T2 (de) 1991-09-02 2000-05-31 Yamanouchi Pharmaceutical Co., Ltd. Triazolylierte tertiäre aminverbindungen oder ihre salze
US5635521A (en) * 1991-09-23 1997-06-03 Sandoz Ltd. Imidazolylmethyl-pyridines
JP2700595B2 (ja) * 1992-05-21 1998-01-21 呉羽化学工業株式会社 アゾール誘導体を含有する抗アロマターゼ剤
RO114327B1 (ro) * 1992-11-10 1999-03-30 Janssen Pharmaceutica Nv Procedeu pentru prepararea 6-/(4-clorofenil)(1h-1,2,4-triazol-1-il)metil/-1-metil-1h-benz otriazolului enantiomeric pur si intermediar pentru prepararea acestuia
CA2150326A1 (en) * 1994-05-27 1995-11-28 Kimihiro Murakami Azolyl methyl phenyl derivatives having aromatase inhibitory activity
WO1997006788A1 (en) * 1995-08-14 1997-02-27 Janssen Pharmaceutica N.V. Transdermal administration of vorozole
IT1286866B1 (it) * 1996-10-28 1998-07-17 Menarini Farma Ind Composti furano-eterociclici,loro preparazione ed uso come inibitori di aromatasi
WO1998028257A1 (fr) * 1996-12-24 1998-07-02 Chugai Seiyaku Kabushiki Kaisha Derives d'amine aromatiques ayant une action inhibitrice a l'egard des nos
AU2001264223A1 (en) * 2000-06-28 2002-01-08 Ssp Co., Ltd. Imidazole derivatives or salts thereof and drugs containing the derivatives or the salts
US7135575B2 (en) 2003-03-03 2006-11-14 Array Biopharma, Inc. P38 inhibitors and methods of use thereof
WO2004078116A2 (en) * 2003-03-03 2004-09-16 Array Biopharma, Inc. P38 inhibitors and methods of use thereof
JP5475235B2 (ja) 2005-01-21 2014-04-16 アステックス・セラピューティクス・リミテッド 医薬化合物
WO2006117307A2 (en) * 2005-04-29 2006-11-09 Janssen Pharmaceutica N.V. Benzotriazole derivatives as cannabinoid receptor antagonists
US7572807B2 (en) * 2005-06-09 2009-08-11 Bristol-Myers Squibb Company Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors
EP1934241B1 (en) 2005-09-15 2012-11-14 Council of Scientific and Industrial Research Novel series of imidazolyl substituted steroidal and indan-1-one derivatives
EP1981851B1 (en) 2006-01-31 2012-01-25 Array Biopharma, Inc. Kinase inhibitors and methods of use thereof
WO2008044045A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
EP2073803B1 (en) 2006-10-12 2018-09-19 Astex Therapeutics Limited Pharmaceutical combinations
WO2012052540A1 (en) * 2010-10-21 2012-04-26 Universitaet Des Saarlandes Selective cyp11b1 inhibitors for the treatment of cortisol dependent diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR75101B (uk) * 1980-10-23 1984-07-13 Pfizer
US4801594A (en) * 1984-06-18 1989-01-31 Eli Lilly And Company Aromatase inhibitors
US4659730A (en) * 1984-06-18 1987-04-21 Eli Lilly And Company Aromatase inhibiting imidazole derivatives
US4602025A (en) * 1984-06-18 1986-07-22 Eli Lilly And Company Aromatase inhibitors
US4609666A (en) * 1984-06-18 1986-09-02 Eli Lilly And Company Aromatase inhibiting derivatives of α,α-bis(4-halophenyl)methyltetrazoles and triazoles
EP0165781A1 (en) * 1984-06-18 1985-12-27 Eli Lilly And Company Aromatase inhibiting N-substituted imidazole derivatives
DE3744589C1 (de) 1987-12-31 1988-12-29 Albrecht Josef Bohrfutter Nachspannendes Bohrfutter

Also Published As

Publication number Publication date
KR890000469A (ko) 1989-03-14
DK295288D0 (da) 1988-05-31
DE3884055T2 (de) 1994-01-27
EP0293978A3 (en) 1990-06-13
DE3884055D1 (de) 1993-10-21
CN1022184C (zh) 1993-09-22
BG60429B2 (bg) 1995-03-31
FI90078C (fi) 1993-12-27
PT87623A (pt) 1988-06-01
NZ224714A (en) 1990-03-27
NO169900B (no) 1992-05-11
EP0293978A2 (en) 1988-12-07
DK175218B1 (da) 2004-07-12
IE881640L (en) 1988-12-01
AU603446B2 (en) 1990-11-15
ES2059490T3 (es) 1994-11-16
JPS63316775A (ja) 1988-12-26
HU201056B (en) 1990-09-28
JPH0662612B2 (ja) 1994-08-17
KR970000952B1 (ko) 1997-01-21
FI882552A0 (fi) 1988-05-31
NO169900C (no) 1992-08-19
LT3950B (en) 1996-05-27
LTIP1625A (en) 1995-07-25
FI90078B (fi) 1993-09-15
AU1653788A (en) 1988-12-01
IE61823B1 (en) 1994-11-30
HU211482A9 (en) 1995-11-28
CN88103408A (zh) 1988-12-14
RU1838308C (ru) 1993-08-30
BG50278A3 (en) 1992-06-15
EP0293978B1 (en) 1993-09-15
FI882552A (fi) 1988-12-02
PT87623B (pt) 1992-09-30
CY1866A (en) 1988-05-26
NO882390D0 (no) 1988-05-31
CA1307271C (en) 1992-09-08
IL86551A0 (en) 1988-11-15
ZA883861B (en) 1990-01-31
LV10452A (lv) 1995-02-20
NO882390L (no) 1988-12-02
HK114795A (en) 1995-07-21
HUT49132A (en) 1989-08-28
IL86551A (en) 1992-07-15
LV10452B (en) 1995-08-20
DK295288A (da) 1988-12-02

Similar Documents

Publication Publication Date Title
UA11192A (uk) Спосіб отримаhhя похідhих заміщеhого
FI890508A (fi) Menetelmä farmaseuttisesti aktiivisten 3-indolipalorypälehappojohdannaisten valmistamiseksi
EA199900494A1 (ru) Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола
ES2136338T3 (es) Derivados de camptotecina y su utilizacion como agente antitumoral.
FR2405931A1 (fr) Nouveaux derives de la phenylethanolamine utiles comme agents antihypertensifs et leur procede de preparation
UA45942A (uk) 1,3-оксатіолан, його похідні, спосіб (варіанти) його одержання та фармацевтична композиція
BE900941A (fr) NOUVEAUX DERIVES DE LA CARBOXYMETHOXY-7 FURO-(3,4-c)-PYRIDINE, LEUR PREPARATION ET COMPOSITIONS THERAPEUTIQUES A BASE DE CES COMPOSES.
FR2405937A1 (fr) Nouveaux derives de dihydropyridine, leur procede de preparation et leur application
DE3873007D1 (de) Kathartica.
ES2084339T3 (es) Tetrahidropiridinas e hidroxipiperidinas sustituidas utiles como agentes para el sistema nervioso central.
SE8703169D0 (sv) 1-(4-aminophenyl)-4-methyl-7,8-methylenedioxy-3,4-dihydro-5h-2,3-benzodiazepine, acid addition salts thereof and process for preparing same
KR900700495A (ko) 치료제로서 유용한 치환된 아데닌 유도체
FR2403330A1 (fr) Nouveaux derives de benzoyl-2-chloro-4-glycinanilides substitues, leur procede de preparation et leur application en tant que medicaments
ES8705411A1 (es) Procedimiento para preparar derivados de 1-piperazinacarboxamida
FR2394522A1 (fr) Nouveaux derives d'acides (s-phenenyl tris(carbonylimino))-5,5',5''tri-benzene-carboxyliques utiles notamment comme inhibiteurs du complement, et leur procede de preparation
FR2388804A1 (fr) Nouveaux derives des acides oxazole- et thiazole-alkanoiques et leur application en therapeutique humaine
DE3268024D1 (en) 0-alkyl-0-carbamoyl-glycero-phospho-cholines and process for their preparation
EA200000448A1 (ru) Новые полиморфные формы ципамфиллина
DE3362725D1 (en) Carbamyloxybenzhydrole derivatives, process for their preparation and pharmaceutical compositions containing them
FR2389631A1 (uk)
FR2359116A1 (fr) N-alkyldiphenylamines
FR2397427A1 (fr) Derives de steroide et leur procede de preparation
FR2377417A1 (fr) Nouveaux derives steroides substitues en 11b, ainsi que leur procede de preparation
OA09451A (fr) "Nouveaux dérivés de la pyrrolidone, leur procédé de préparation et les compositions pharmaceutiques les renfermant".
FR2428636A1 (fr) Nouveaux acides dihydrobenzofurannylacetiques a-substitues, et leur preparation