TWI840351B - T細胞受體及表現其之工程化細胞 - Google Patents

T細胞受體及表現其之工程化細胞 Download PDF

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TWI840351B
TWI840351B TW108112029A TW108112029A TWI840351B TW I840351 B TWI840351 B TW I840351B TW 108112029 A TW108112029 A TW 108112029A TW 108112029 A TW108112029 A TW 108112029A TW I840351 B TWI840351 B TW I840351B
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amino acid
seq
region
tcr
cdr
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TW108112029A
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TW202005658A (zh
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史蒂芬 雅各伯 葛德勒斯
凱麥隆 布朗特
布萊恩 波默特
亞莉珊卓 寇特
大衛 傑佛瑞 胡斯
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美商奇諾治療有限公司
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    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/01—DNA viruses
    • C07K14/025—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
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    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
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TW108112029A 2018-04-05 2019-04-03 T細胞受體及表現其之工程化細胞 TWI840351B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862653516P 2018-04-05 2018-04-05
US62/653,516 2018-04-05
US201862739145P 2018-09-28 2018-09-28
US62/739,145 2018-09-28

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TW202005658A TW202005658A (zh) 2020-02-01
TWI840351B true TWI840351B (zh) 2024-05-01

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EP (1) EP3773908A1 (enExample)
JP (1) JP7410868B2 (enExample)
KR (1) KR102764123B1 (enExample)
CN (1) CN112566698A (enExample)
AU (1) AU2019249209A1 (enExample)
BR (1) BR112020019313A2 (enExample)
CA (1) CA3095027A1 (enExample)
CL (1) CL2020002545A1 (enExample)
CO (1) CO2020013499A2 (enExample)
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RU (1) RU2020135968A (enExample)
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