TWI720984B - 用於防止上皮細胞增生及上皮-間質轉移之組合物及方法 - Google Patents

用於防止上皮細胞增生及上皮-間質轉移之組合物及方法 Download PDF

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TWI720984B
TWI720984B TW105115893A TW105115893A TWI720984B TW I720984 B TWI720984 B TW I720984B TW 105115893 A TW105115893 A TW 105115893A TW 105115893 A TW105115893 A TW 105115893A TW I720984 B TWI720984 B TW I720984B
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ptx3
composition
cells
fetal support
support tissue
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TW105115893A
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TW201709916A (zh
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薛佛 曾
伊克 奇亞 譚
華 何
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美商帝聖工業公司
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/50Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/51Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
TW105115893A 2015-05-20 2016-05-20 用於防止上皮細胞增生及上皮-間質轉移之組合物及方法 TWI720984B (zh)

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US201562164281P 2015-05-20 2015-05-20
US62/164,281 2015-05-20

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TW201709916A TW201709916A (zh) 2017-03-16
TWI720984B true TWI720984B (zh) 2021-03-11

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US (3) US10342831B2 (https=)
EP (1) EP3297645A4 (https=)
JP (1) JP2018516869A (https=)
CN (1) CN107847526A (https=)
CA (1) CA2984443A1 (https=)
HK (1) HK1250940A1 (https=)
TW (1) TWI720984B (https=)
WO (1) WO2016187555A1 (https=)

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TW201603818A (zh) 2014-06-03 2016-02-01 組織科技股份有限公司 組成物及方法
EP3200809B1 (en) 2014-10-02 2023-09-13 Wake Forest University Health Sciences, Inc. Amniotic membrane powder and its use in wound healing and tissue engineering constructs
US20160243288A1 (en) 2015-02-23 2016-08-25 Tissuetech, Inc. Apparatuses and methods for treating ophthalmic diseases and disorders
JP2018516869A (ja) 2015-05-20 2018-06-28 ティッシュテック,インク. 上皮細胞の増殖および上皮間葉転換を防ぐための組成物および方法
CN109069867B (zh) * 2016-03-14 2022-02-01 无痛疗法股份有限公司 无细胞胎盘制剂
US11285177B2 (en) 2018-01-03 2022-03-29 Globus Medical, Inc. Allografts containing viable cells and methods thereof
EP3876963A4 (en) * 2018-11-07 2022-08-17 Tissuetech, Inc. PROCEDURE FOR CELL REPROGRAMMING
AU2020260133A1 (en) * 2019-04-16 2021-11-18 Lifenet Health Birth tissue-derived products and preparation and uses thereof
CN111019884B (zh) * 2019-12-31 2022-01-07 上海赛比曼生物科技有限公司 一种抑制人羊膜上皮细胞上皮间质转化的方法
EP4103592A4 (en) * 2020-02-12 2024-01-10 BioTissue Holdings Inc. METHODS OF DESTRUCTING OR INHIBITING THE GROWTH OF CANCER CELLS
US20240000704A1 (en) * 2020-04-03 2024-01-04 Tissuetech, Inc. Methods of using umbilical cord products for treatment of ocular surface disorders
WO2021226060A1 (en) * 2020-05-04 2021-11-11 Genesis Biologics, Inc. Formulations of hyaluronic acid and amniotic or gestational fluid, and uses of the same
CN116723848A (zh) * 2020-10-26 2023-09-08 生物组织控股公司 用于加工胎儿支持组织的方法
CA3212378A1 (en) * 2021-03-02 2022-09-09 Auckland Uniservices Limited Compositions and methods for modulating epithelial-mesenchymal transition
WO2023211823A1 (en) * 2022-04-25 2023-11-02 Biotissue Holdings Inc. Compositions and methods relating to pooled fetal support tissue
CN115804665A (zh) * 2022-12-13 2023-03-17 南昌大学附属眼科医院 一种tpvr动物模型的建立方法

Citations (1)

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Publication number Priority date Publication date Assignee Title
CN104619352A (zh) * 2012-07-11 2015-05-13 组织技术公司 含有hc-ha/ptx3复合物的组合物及其使用方法

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