JP2018516869A - 上皮細胞の増殖および上皮間葉転換を防ぐための組成物および方法 - Google Patents

上皮細胞の増殖および上皮間葉転換を防ぐための組成物および方法 Download PDF

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Publication number
JP2018516869A
JP2018516869A JP2017555269A JP2017555269A JP2018516869A JP 2018516869 A JP2018516869 A JP 2018516869A JP 2017555269 A JP2017555269 A JP 2017555269A JP 2017555269 A JP2017555269 A JP 2017555269A JP 2018516869 A JP2018516869 A JP 2018516869A
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ptx3
composition
fetal support
support tissue
injection
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JP2018516869A5 (https=
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ツェン，シェフェール
キア タン，エック
キア タン，エック
ヘ，フア
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ティッシュテック，インク．
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2017555269A 2015-05-20 2016-05-20 上皮細胞の増殖および上皮間葉転換を防ぐための組成物および方法 Pending JP2018516869A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562164281P 2015-05-20 2015-05-20
US62/164,281 2015-05-20
PCT/US2016/033558 WO2016187555A1 (en) 2015-05-20 2016-05-20 Compositions and methods for preventing the proliferation and epithelial-mesenchymal transition of epithelial cells

Publications (2)

Publication Number Publication Date
JP2018516869A true JP2018516869A (ja) 2018-06-28
JP2018516869A5 JP2018516869A5 (https=) 2019-06-20

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JP2017555269A Pending JP2018516869A (ja) 2015-05-20 2016-05-20 上皮細胞の増殖および上皮間葉転換を防ぐための組成物および方法

Country Status (8)

Country Link
US (3) US10342831B2 (https=)
EP (1) EP3297645A4 (https=)
JP (1) JP2018516869A (https=)
CN (1) CN107847526A (https=)
CA (1) CA2984443A1 (https=)
HK (1) HK1250940A1 (https=)
TW (1) TWI720984B (https=)
WO (1) WO2016187555A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023519954A (ja) * 2020-04-03 2023-05-15 ティッシュテック，インク． 眼表面障害の処置のための臍帯生成物の使用方法
JP2023546994A (ja) * 2020-10-26 2023-11-08 バイオティシュー ホールディングス インク． 胎児支持組織を処理する方法

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8187639B2 (en) 2005-09-27 2012-05-29 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment
US8182840B2 (en) 2005-09-27 2012-05-22 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and therapy for scar reversal and inhibition
CN103874762A (zh) 2011-08-26 2014-06-18 组织技术公司 胎儿支持组织的灭菌方法
ES2846789T3 (es) 2012-07-11 2021-07-29 Tissuetech Inc Composiciones que contienen complejos HC-HA/PTX3 y métodos de uso de los mismos
EP2897625B1 (en) 2012-09-10 2019-10-23 Wake Forest University Health Sciences Amniotic membrane and its use in wound healing and tissue engineering constructs
TW201603818A (zh) 2014-06-03 2016-02-01 組織科技股份有限公司 組成物及方法
EP3200809B1 (en) 2014-10-02 2023-09-13 Wake Forest University Health Sciences, Inc. Amniotic membrane powder and its use in wound healing and tissue engineering constructs
US20160243288A1 (en) 2015-02-23 2016-08-25 Tissuetech, Inc. Apparatuses and methods for treating ophthalmic diseases and disorders
JP2018516869A (ja) 2015-05-20 2018-06-28 ティッシュテック，インク． 上皮細胞の増殖および上皮間葉転換を防ぐための組成物および方法
CN109069867B (zh) * 2016-03-14 2022-02-01 无痛疗法股份有限公司 无细胞胎盘制剂
US11285177B2 (en) 2018-01-03 2022-03-29 Globus Medical, Inc. Allografts containing viable cells and methods thereof
EP3876963A4 (en) * 2018-11-07 2022-08-17 Tissuetech, Inc. PROCEDURE FOR CELL REPROGRAMMING
AU2020260133A1 (en) * 2019-04-16 2021-11-18 Lifenet Health Birth tissue-derived products and preparation and uses thereof
CN111019884B (zh) * 2019-12-31 2022-01-07 上海赛比曼生物科技有限公司 一种抑制人羊膜上皮细胞上皮间质转化的方法
EP4103592A4 (en) * 2020-02-12 2024-01-10 BioTissue Holdings Inc. METHODS OF DESTRUCTING OR INHIBITING THE GROWTH OF CANCER CELLS
WO2021226060A1 (en) * 2020-05-04 2021-11-11 Genesis Biologics, Inc. Formulations of hyaluronic acid and amniotic or gestational fluid, and uses of the same
CA3212378A1 (en) * 2021-03-02 2022-09-09 Auckland Uniservices Limited Compositions and methods for modulating epithelial-mesenchymal transition
WO2023211823A1 (en) * 2022-04-25 2023-11-02 Biotissue Holdings Inc. Compositions and methods relating to pooled fetal support tissue
CN115804665A (zh) * 2022-12-13 2023-03-17 南昌大学附属眼科医院 一种tpvr动物模型的建立方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015052714A1 (en) * 2013-10-07 2015-04-16 Mor Research Applications Ltd. Treatments for proliferative vitreoretinopathy
JP2015528001A (ja) * 2012-07-11 2015-09-24 ティッシュテック，インク． Ｈｃ−ｈａ／ｐｔｘ３複合体を含む組成物およびその使用方法

Family Cites Families (192)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3598122A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3993073A (en) 1969-04-01 1976-11-23 Alza Corporation Novel drug delivery device
US3598123A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3710795A (en) 1970-09-29 1973-01-16 Alza Corp Drug-delivery device with stretched, rate-controlling membrane
US4069307A (en) 1970-10-01 1978-01-17 Alza Corporation Drug-delivery device comprising certain polymeric materials for controlled release of drug
JPS4943153B1 (https=) 1970-12-05 1974-11-19
US3731683A (en) 1971-06-04 1973-05-08 Alza Corp Bandage for the controlled metering of topical drugs to the skin
US3996934A (en) 1971-08-09 1976-12-14 Alza Corporation Medical bandage
US3742951A (en) 1971-08-09 1973-07-03 Alza Corp Bandage for controlled release of vasodilators
BE795384A (fr) 1972-02-14 1973-08-13 Ici Ltd Pansements
US3921636A (en) 1973-01-15 1975-11-25 Alza Corp Novel drug delivery device
US3993072A (en) 1974-08-28 1976-11-23 Alza Corporation Microporous drug delivery device
US3972995A (en) 1975-04-14 1976-08-03 American Home Products Corporation Dosage form
US4141973A (en) * 1975-10-17 1979-02-27 Biotrics, Inc. Ultrapure hyaluronic acid and the use thereof
US4077407A (en) 1975-11-24 1978-03-07 Alza Corporation Osmotic devices having composite walls
US4031894A (en) 1975-12-08 1977-06-28 Alza Corporation Bandage for transdermally administering scopolamine to prevent nausea
US4060084A (en) 1976-09-07 1977-11-29 Alza Corporation Method and therapeutic system for providing chemotherapy transdermally
US4201211A (en) 1977-07-12 1980-05-06 Alza Corporation Therapeutic system for administering clonidine transdermally
CA1097233A (en) 1977-07-20 1981-03-10 George K. E. Gregory Packages
JPS5562012A (en) 1978-11-06 1980-05-10 Teijin Ltd Slow-releasing preparation
US4230105A (en) 1978-11-13 1980-10-28 Merck & Co., Inc. Transdermal delivery of drugs
US4291015A (en) 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
US4327725A (en) 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
US4347841A (en) 1981-03-11 1982-09-07 Human Oltoanyagtermelo Es Kutato Intezet Biological wound covering and method for producing same
US4476116A (en) 1982-12-10 1984-10-09 Syntex (U.S.A.) Inc. Polypeptides/chelating agent nasal compositions having enhanced peptide absorption
US5116817A (en) 1982-12-10 1992-05-26 Syntex (U.S.A.) Inc. LHRH preparations for intranasal administration
US5093487A (en) 1986-01-06 1992-03-03 Mobay Corporation Low viscosity high molecular weight filter sterilizable hyaluronic acid
US4624848A (en) 1984-05-10 1986-11-25 Ciba-Geigy Corporation Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use
GB8518301D0 (en) 1985-07-19 1985-08-29 Fujisawa Pharmaceutical Co Hydrodynamically explosive systems
US5011692A (en) 1985-12-28 1991-04-30 Sumitomo Pharmaceuticals Company, Limited Sustained pulsewise release pharmaceutical preparation
GB8708009D0 (en) 1987-04-03 1987-05-07 Clayton Found Res Injectable soft tissue augmentation materials
US5312325A (en) 1987-05-28 1994-05-17 Drug Delivery Systems Inc Pulsating transdermal drug delivery system
US4968509A (en) 1987-07-27 1990-11-06 Mcneilab, Inc. Oral sustained release acetaminophen formulation and process
US5052558A (en) 1987-12-23 1991-10-01 Entravision, Inc. Packaged pharmaceutical product
IL92966A (en) 1989-01-12 1995-07-31 Pfizer Dispensing devices powered by hydrogel
US5192744A (en) 1990-01-12 1993-03-09 Northwestern University Method of inhibiting angiogenesis of tumors
US5017381A (en) 1990-05-02 1991-05-21 Alza Corporation Multi-unit pulsatile delivery system
US5633009A (en) 1990-11-28 1997-05-27 Sano Corporation Transdermal administration of azapirones
KR0182801B1 (ko) 1991-04-16 1999-05-01 아만 히데아키 고체 분산체의 제조방법
US5229135A (en) 1991-11-22 1993-07-20 Prographarm Laboratories Sustained release diltiazem formulation
CZ282760B6 (cs) 1991-11-22 1997-09-17 Procter And Gamble Pharmaceuticals, Inc. Risedronátové prostředky se zpožděným uvolňováním
JP3337488B2 (ja) 1992-03-06 2002-10-21 アベンティス ファーマ株式会社 切迫流産治療剤
US5461140A (en) 1992-04-30 1995-10-24 Pharmaceutical Delivery Systems Bioerodible polymers for solid controlled release pharmaceutical compositions
US5260068A (en) 1992-05-04 1993-11-09 Anda Sr Pharmaceuticals Inc. Multiparticulate pulsatile drug delivery system
US5437287A (en) 1992-08-17 1995-08-01 Carbomedics, Inc. Sterilization of tissue implants using iodine
DE69332291T2 (de) 1992-10-16 2003-07-31 Nippon Shinyaku Co., Ltd. Verfahren zur herstellung von wachsmatrizes
US5260069A (en) 1992-11-27 1993-11-09 Anda Sr Pharmaceuticals Inc. Pulsatile particles drug delivery system
US5686105A (en) 1993-10-19 1997-11-11 The Procter & Gamble Company Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery
JP3010980B2 (ja) 1993-07-29 2000-02-21 日産自動車株式会社 自動組立て設備における取付けミス位置表示装置
US6203755B1 (en) 1994-03-04 2001-03-20 St. Jude Medical, Inc. Electron beam sterilization of biological tissues
US5665378A (en) 1994-09-30 1997-09-09 Davis; Roosevelt Transdermal therapeutic formulation
US5567441A (en) 1995-03-24 1996-10-22 Andrx Pharmaceuticals Inc. Diltiazem controlled release formulation
JPH11505258A (ja) 1995-05-17 1999-05-18 セダーシナイ メディカル センター 小腸における消化および吸収を改善させる脂肪酸を含む組成物
US5837284A (en) 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
US6929801B2 (en) 1996-02-19 2005-08-16 Acrux Dds Pty Ltd Transdermal delivery of antiparkinson agents
US6923983B2 (en) 1996-02-19 2005-08-02 Acrux Dds Pty Ltd Transdermal delivery of hormones
US6632648B1 (en) 1996-05-14 2003-10-14 Elan Drug Delivery Limited Methods of terminal sterilization of fibrinogen
US6152142A (en) 1997-02-28 2000-11-28 Tseng; Scheffer C. G. Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries
US5932545A (en) 1997-03-17 1999-08-03 Abbott Laboratories Antiangiogenic drug to treat cancer, arthritis and retinopathy
US5840329A (en) 1997-05-15 1998-11-24 Bioadvances Llc Pulsatile drug delivery system
US6391452B1 (en) 1997-07-18 2002-05-21 Bayer Corporation Compositions for nasal drug delivery, methods of making same, and methods of removing residual solvent from pharmaceutical preparations
US5869090A (en) 1998-01-20 1999-02-09 Rosenbaum; Jerry Transdermal delivery of dehydroepiandrosterone
US6946144B1 (en) 1998-07-08 2005-09-20 Oryxe Transdermal delivery system
US20030068815A1 (en) 1999-02-11 2003-04-10 Stone Kevin R. Sterilized xenograft tissue
US6395300B1 (en) 1999-05-27 2002-05-28 Acusphere, Inc. Porous drug matrices and methods of manufacture thereof
US6046160A (en) 1999-07-22 2000-04-04 Deroyal Industries, Inc. Composition and method for enhancing wound healing
US6521179B1 (en) 1999-08-11 2003-02-18 Biomedical Design, Inc. Sterilization
US6573249B2 (en) 2000-02-15 2003-06-03 Alphamed Pharmaceutical Corp. Topical wound therapeutic compositions
US10281478B2 (en) 2000-04-06 2019-05-07 Wayne P. Franco Combination growth factor therapy and cell therapy for treatment of acute and chronic diseases of the organs
KR20010098716A (ko) 2000-04-19 2001-11-08 김재찬 안구표면질환 치료용 양막 추출물
US6465014B1 (en) 2001-03-21 2002-10-15 Isp Investments Inc. pH-dependent sustained release, drug-delivery composition
WO2003024496A1 (en) 2001-09-05 2003-03-27 Hans Biomed Corporation A process for preparing a biomaterial for tissue repair
US20030180181A1 (en) 2002-02-01 2003-09-25 Teri Greib Methods for sterilizing tissue
TWI290055B (en) 2002-03-14 2007-11-21 Tissuetech Inc Amniotic membrane covering for a tissue surface and devices facilitating fastening of membranes
US20030187515A1 (en) 2002-03-26 2003-10-02 Hariri Robert J. Collagen biofabric and methods of preparing and using the collagen biofabric
EP1509236A4 (en) 2002-05-13 2008-07-30 Children S Hospital Los Angele TREATMENT AND PREVENTION OF ABNORMAL SCALING IN KELOIDS AND OTHER SKIN OR INTERNAL WOUNDS OR LESIONS
US20040091503A1 (en) 2002-08-20 2004-05-13 Genitrix, Llc Lectin compositions and methods for modulating an immune response to an antigen
DK1530469T3 (da) 2002-08-20 2009-05-04 Euro Celtique Sa Transdermal dosisform omfattende et aktivt middel og et salt og fri baseform af en antagonist
EP1549328A4 (en) 2002-09-18 2009-07-08 Emiliano Ghinelli USE OF A HUMAN SHEEP SKIN COMPOSITION FOR PROPHYLAXIS AND TREATMENT OF DISEASES AND STATES OF EYE AND SKIN
WO2004033635A2 (en) 2002-10-04 2004-04-22 Tissuetech, Inc. Retinal pigment epithelial cell cultures on amniotic membrane and transplantation
KR100794289B1 (ko) 2002-11-08 2008-01-11 아이진 주식회사 Ｂｍｐ-7 폴리펩타이드를 포함하는 흉터 형성 억제제
EP1604695A1 (en) 2003-02-26 2005-12-14 Amniotec Inc. Amnion-origin medical material and method of preparing the same
EP2399990B1 (en) 2003-06-27 2015-07-22 DePuy Synthes Products, Inc. Cells derived from post-partum umbilical cord for use in treatment of disease of the heart and circulatory system
ITRM20030595A1 (it) 2003-12-23 2005-06-24 Sigma Tau Ind Farmaceuti Uso della ptx3 o di un suo derivato funzionale da sola o in associazione con tsg6 per il trattamento di patologie degenarative dell'osso o della cartilagine e per il trattamento della infertilita' femminile.
KR101322889B1 (ko) 2004-08-16 2013-10-30 셀리서치 코포레이션 피티이 리미티드 제대의 양막으로부터 줄기/전구세포의 추출
WO2006094247A2 (en) 2005-03-02 2006-09-08 Tissuetech, Inc. Amniotic membrane extracts, compositions thereof, and methods of use
WO2007011693A2 (en) 2005-07-14 2007-01-25 Medistem Laboratories, Inc. Compositions of placentally-derived stem cells for the treatment of cancer
GB0514567D0 (en) 2005-07-15 2005-08-24 Univ Nottingham Surgical membrane
CN1903073A (zh) 2005-07-26 2007-01-31 孙甜甜 胎元素保健品的制造方法
US8187639B2 (en) 2005-09-27 2012-05-29 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment
US8182840B2 (en) 2005-09-27 2012-05-22 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and therapy for scar reversal and inhibition
CN103173401A (zh) 2005-12-22 2013-06-26 简·恩尼斯 来自冷冻的脐带组织的活细胞
US9944900B2 (en) 2006-01-18 2018-04-17 Hemacell Perfusion Pulsatile perfusion extraction method for non-embryonic pluripotent stem cells
US20180008649A1 (en) 2006-03-23 2018-01-11 Pluristem Ltd. Adherent stromal cells derived from placentas of multiple donors and uses thereof
US20080050814A1 (en) 2006-06-05 2008-02-28 Cryo-Cell International, Inc. Procurement, isolation and cryopreservation of fetal placental cells
WO2008003042A2 (en) 2006-06-28 2008-01-03 The University Of Medicine And Dentistry Of New Jersey Amnion-derived stem cells and uses thereof
WO2008021391A1 (en) 2006-08-15 2008-02-21 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
US8372437B2 (en) 2006-08-17 2013-02-12 Mimedx Group, Inc. Placental tissue grafts
WO2008042441A1 (en) 2006-10-03 2008-04-10 Anthrogenesis Corporation Use of umbilical cord biomaterial for ocular surgery
WO2008060377A2 (en) 2006-10-04 2008-05-22 Anthrogenesis Corporation Placental or umbilical cord tissue compositions
US20080102135A1 (en) 2006-10-28 2008-05-01 Franck Jean Ollivier Use of equine amniotic membrane in ophthalmic surgeries in veterinary medicine
EP4559488A3 (en) 2007-09-07 2025-08-13 MiMedx Group, Inc. Placental tissue grafts and improved methods of preparing and using the same
WO2009111159A2 (en) 2008-03-03 2009-09-11 New York University Biocompatible materials containing stable complexes of tsg-6 and hyaluronan and method of using same
ES2559029T3 (es) 2009-04-24 2016-02-10 Tissue Tech, Inc. Composiciones que contienen al complejo HC.HA y metodos de uso de las mismas
CA2771908C (en) 2009-08-25 2019-05-21 Tissuetech, Inc. Umbilical cord amniotic membrane products
EP3351625A1 (en) 2010-02-18 2018-07-25 Osiris Therapeutics, Inc. Methods of manufacture of immunocompatible amniotic membrane products
EP2555783A1 (en) 2010-04-08 2013-02-13 Anthrogenesis Corporation Treatment of sarcoidosis using placental stem cells
EP2576768B1 (en) 2010-06-01 2017-05-10 Auxocell Laboratories, Inc. Native wharton's jelly stem cells and their purification
US8840665B2 (en) 2010-06-11 2014-09-23 Liventa Bioscience, Inc. Method of tendon repair with amnion and chorion constructs
US20130156863A1 (en) 2010-06-30 2013-06-20 Tissuetech, Inc. Methods of preparing chorion tissue and products derived therefrom
US20120010727A1 (en) 2010-07-06 2012-01-12 AFcell Medical Amnion and chorion constructs and uses thereof in sport injury surgeries
US20120010708A1 (en) 2010-07-08 2012-01-12 AFcell Medical Amnion and chorion replacement cover and uses thereof in surgical repair of muscles
US20120020933A1 (en) 2010-07-22 2012-01-26 AFcell Medical Method of nerve repair with amnion and chorion constructs
US20120035743A1 (en) 2010-08-03 2012-02-09 AFcell Medical Amnion and chorion constructs and uses thereof in minimally invasive surgeries
US20120035744A1 (en) 2010-08-04 2012-02-09 AFcell Medical Amnion and chorion constructs and uses thereof in joint repair
SG190069A1 (en) 2010-11-11 2013-06-28 Abbvie Biotechnology Ltd IMPROVED HIGH CONCENTRATION ANTI-TNFa ANTIBODY LIQUID FORMULATIONS
KR102903446B1 (ko) 2011-02-14 2025-12-24 미메딕스 그룹 인크. 마이크로화된 태반 조직 조성물 및 이의 제조 및 사용 방법
US9526770B2 (en) 2011-04-28 2016-12-27 Tissuetech, Inc. Methods of modulating bone remodeling
ES2822301T3 (es) 2011-06-10 2021-04-30 Tissuetech Inc Métodos de procesamiento de tejidos de soporte fetal
CN103874762A (zh) 2011-08-26 2014-06-18 组织技术公司 胎儿支持组织的灭菌方法
US8932805B1 (en) 2011-10-31 2015-01-13 BioDlogics, LLC Birth tissue material and method of preparation
US9162011B2 (en) 2011-12-19 2015-10-20 Allosource Flowable matrix compositions and methods
HUE056817T2 (hu) 2011-12-30 2022-03-28 Amit Patel Eljárások és készítmények allogén sejt klinikai származtatására és terápiás alkalmazások
US20130209524A1 (en) 2012-02-14 2013-08-15 AFcell Medical Method of using amnion allograft in heart transplant surgery
US20130211504A1 (en) 2012-02-14 2013-08-15 AFcell Medical Method of using amnion allograft in heart valve repair surgery
US20130211502A1 (en) 2012-02-14 2013-08-15 AFcell Medical Method of using amnion allograft in coronary artery bypass grafting
US9416410B2 (en) 2012-02-14 2016-08-16 Genetics Development Corporation Cutoff point delta Ct. method for HER2 PCR testing in breast cancer
US8961617B2 (en) 2012-03-08 2015-02-24 Liventa Bioscience, Inc. Amnion and chorion constructs and uses thereof in abdominal surgery
US20130236506A1 (en) 2012-03-08 2013-09-12 AFcell Medical Amnion and chorion constructs and uses thereof in ob-gyn surgery
US20130289724A1 (en) 2012-04-25 2013-10-31 AFcell Medical Amnion and chorion wound dressing and uses thereof
US8904664B2 (en) 2012-08-15 2014-12-09 Mimedx Group, Inc. Dehydration device and methods for drying biological materials
US9943551B2 (en) 2012-08-15 2018-04-17 Mimedx Group, Inc. Tissue grafts composed of micronized placental tissue and methods of making and using the same
US11338063B2 (en) 2012-08-15 2022-05-24 Mimedx Group, Inc. Placental tissue grafts modified with a cross-linking agent and methods of making and using the same
US20140186461A1 (en) 2012-09-10 2014-07-03 Alpha Tissue, Inc. Human Amniotic Membrane Lyophilized Grafts
US20140106447A1 (en) 2012-10-12 2014-04-17 Mimedx Group, Inc. Compositions and methods for recruiting stem cells
US9180145B2 (en) 2012-10-12 2015-11-10 Mimedx Group, Inc. Compositions and methods for recruiting and localizing stem cells
US10517931B2 (en) 2013-01-17 2019-12-31 Mimedx Group, Inc. Non-surgical, localized delivery of compositions for placental growth factors
US9827293B2 (en) 2013-01-17 2017-11-28 Mimedx Group, Inc. Non-surgical, localized delivery of compositions for placental growth factors
US10111910B2 (en) 2013-01-18 2018-10-30 Mimedx Group, Inc. Methods for treating cardiac conditions
US9498327B1 (en) 2013-03-05 2016-11-22 Biodlogics Llc Repair of tympanic membrane using human birth tissue material
US9855301B1 (en) 2013-03-13 2018-01-02 Biodlogics Llc Human birth tissue laminate and methods of use
ES2968068T3 (es) 2013-03-15 2024-05-07 Prime Merger Sub Llc Preparaciones derivadas de materiales placentarios y métodos para fabricarlas y utilizarlas
US10029030B2 (en) 2013-03-15 2018-07-24 Mimedx Group, Inc. Molded placental tissue compositions and methods of making and using the same
US9795639B1 (en) 2013-03-16 2017-10-24 BioDlogics, LLC Methods for the treatment of erectile dysfunction by human birth tissue material compostion
US9993506B1 (en) 2013-03-16 2018-06-12 BioDlogics, Inc. Methods for the treatment of degenerative disc diseases by human birth tissue material composition
KR20150139569A (ko) 2013-04-02 2015-12-11 유니버시티 오브 플로리다 리서치 파운데이션, 인크. 혈관형성의 유도 및 조절을 위한 조성물 및 방법 및 혈관형성 조절 인자를 확인하기 위한 방법 및 분석법
US10485521B2 (en) 2013-05-10 2019-11-26 MAM Holdings of West Florida, L.L.C. Method for obtaining sterile human amniotic fluid and uses thereof
GB201309963D0 (en) 2013-06-04 2013-07-17 Univ Nottingham Amniotic membrane
KR20150016788A (ko) 2013-08-05 2015-02-13 삼성전자주식회사 단말기에 부착된 커버의 개폐 상태를 인지하는 방법 및 장치.
JP2016529070A (ja) 2013-09-10 2016-09-23 ミメディクス グループ インコーポレイテッド 成形胎盤組成物の美容的使用
CN106459908B (zh) 2014-01-08 2019-12-13 社会福祉法人三星生命公益财团 来源于纯滋养层的干细胞及包含其的细胞治疗剂
EP3094336A4 (en) 2014-01-17 2018-02-14 MIMEDX Group Inc. Method for inducing angiogenesis
US9814746B2 (en) 2014-06-15 2017-11-14 Amnio Technology Llc Method of treatment utilizing an acellular amnion derived therapeutic composition
WO2015175776A1 (en) 2014-05-14 2015-11-19 NuTech Medical, Inc. Placental membrane preparations and methods of making and using same for regenerating cartilage and spinal intervertebral discs
US9867641B2 (en) 2014-05-15 2018-01-16 Brahm Holdings, Llc Spinal graft
EP3146039A4 (en) 2014-05-21 2017-11-29 MiMedx Group, Inc. Micronized wharton's jelly
WO2016007554A1 (en) 2014-07-08 2016-01-14 Mimedx Group, Inc. Micronized wharton's jelly
JP6909154B2 (ja) 2014-08-14 2021-07-28 アヴィタ・インターナショナル・リミテッド 幹細胞組成物および療法適用のための幹細胞を産生する方法
JP6960333B2 (ja) 2014-09-09 2021-11-05 ミメディクス グループ インコーポレイテッド 任意にシーラントを含む微粒子化胎盤組織の組成物、ならびにその組成物の作製方法および使用方法
US9913466B2 (en) 2014-09-10 2018-03-13 Healthbanks Biotech Co. Ltd. Cryopreservation of umbilical cord tissue strips for cord tissue-derived stem cells
EP3200809B1 (en) 2014-10-02 2023-09-13 Wake Forest University Health Sciences, Inc. Amniotic membrane powder and its use in wound healing and tissue engineering constructs
GB2532499A (en) 2014-11-21 2016-05-25 Virgin Health Bank Qstp-Llc Improvements in tissue processing
US9694109B1 (en) 2015-01-06 2017-07-04 Brahm Holdings, Llc Nanoparticle-containing placental constructs and methods of use
US10517903B2 (en) 2015-09-14 2019-12-31 Amnio Technology Llc Amnion derived therapeutic composition and process of making same
JP2018516869A (ja) 2015-05-20 2018-06-28 ティッシュテック，インク． 上皮細胞の増殖および上皮間葉転換を防ぐための組成物および方法
US10479978B2 (en) 2015-05-28 2019-11-19 Cha Biotech Co., Ltd. Postnatal adherent cells and preparation method therefor
US10006003B2 (en) 2015-06-30 2018-06-26 Surgenex, LLC Compositions and methods for flowable allograft amniotic tissue
AU2016327598B2 (en) 2015-09-23 2023-06-29 Osiris Therapeutics, Inc. Umbilical tissue compositions and methods of use
WO2017096617A1 (zh) 2015-12-11 2017-06-15 郭镭 一种用于分步培养hUC-MSC的试剂盒及采用所述试剂盒获得的hUC-MSC
US20180362923A1 (en) 2015-12-11 2018-12-20 Lei Guo Method for separating and extracting huc-msc from wharton's jelly tissue of umbilical cord
WO2017096616A1 (zh) 2015-12-11 2017-06-15 郭镭 一种无血清培养基及其制备方法和用途
US10993969B2 (en) 2016-02-05 2021-05-04 Gary M. Petrucci Methods and materials for treating nerve injuries and neurological disorders
EP3423119A4 (en) 2016-03-04 2020-02-19 The Board of Regents of The University of Texas System DEVICES AND METHODS FOR CORD PROCESSING
US20170354692A1 (en) 2016-06-13 2017-12-14 MAM Holdings of West Florida, L.L.C. Amniotic fluid formulation for treatment of lung disorders
CA3029233A1 (en) 2016-06-24 2017-12-28 Osiris Therapeutics, Inc. Human tissue derived compositions and uses thereof
US20180110900A1 (en) 2016-08-21 2018-04-26 Michael S. Korenfeld Therapeutic Applications of Honey and Amniotic Membrane for the Treatment of Disease
AU2017316682B2 (en) 2016-08-24 2020-10-15 Arthrex, Inc. Tissue use for repair of injury
TWI689589B (zh) 2016-08-31 2020-04-01 宣捷細胞生物製藥股份有限公司 區別間質幹細胞的方法及測定間質幹細胞的純度的方法
CN109804063B (zh) 2016-10-05 2025-02-25 细胞研究私人有限公司 一种采用细胞培养基自脐带羊膜中分离间充质干细胞的方法
US10745664B2 (en) 2016-10-28 2020-08-18 Reelabs Private Limited, a Company Incorporated Under Provisions of The Companies Act 1956 Method of progenitor cell isolation from different organs by natural destruction of extracellular matrix
US20180126036A1 (en) 2016-11-07 2018-05-10 Ise Professional Testing & Consulting Services, Inc. Decellularized biomaterial from mammalian tissue
TWI645039B (zh) 2016-12-11 2018-12-21 生寶生物科技股份有限公司 無血清培養基及擴增造血幹細胞的方法
US10993904B2 (en) 2016-12-23 2021-05-04 Inscobee Inc. Transplantation implant for promoting hair growth
US20180177989A1 (en) 2016-12-28 2018-06-28 Regen Medical Inc. Vaginal rejuvenation methods and devices
TWI746772B (zh) 2017-01-18 2021-11-21 國立陽明大學 臍帶間質幹細胞用於治療肺部纖維化之用途
US20180264049A1 (en) 2017-03-20 2018-09-20 Batu Biologics, Inc. Immunotherapy of Aberrant Ocular Angiogenesis by Placental Vaccination
US20180271914A1 (en) 2017-03-21 2018-09-27 Noveome Biotherapeutics, Inc. Methods for Reducing the Extent of Light-induced Tissue Inflammation and Injury
US20180311408A1 (en) 2017-05-01 2018-11-01 Trojan Medical Solutions, LLC Amnion based conduit tissue
WO2018220490A1 (en) 2017-06-02 2018-12-06 Janssen Biotech, Inc. Method of modulating müller glia cells
US20180346874A1 (en) 2017-06-02 2018-12-06 Janssen Biotech, Inc. Methods of obtaining cells from human postpartum umbilical cord arterial tissue
TW201932126A (zh) 2017-11-03 2019-08-16 美商健生生物科技公司 抑制血管生成之方法
GB2582521B (en) 2017-11-14 2022-07-13 Cook Biotech Inc Preserved tissue products and related methods

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015528001A (ja) * 2012-07-11 2015-09-24 ティッシュテック，インク． Ｈｃ−ｈａ／ｐｔｘ３複合体を含む組成物およびその使用方法
WO2015052714A1 (en) * 2013-10-07 2015-04-16 Mor Research Applications Ltd. Treatments for proliferative vitreoretinopathy

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
"ARVO Annual Meeting Abstract", IOVS, vol. 56, JPN6020014985, 2015, pages 2287, ISSN: 0004461596 *
J KOREAN OPHTHALMOL SOC, vol. 44, no. 2, JPN6020014991, 2003, pages 459 - 471, ISSN: 0004259320 *
NATIONAL INSTITUTES OF HEALTH, PREVENTION OF PROLIFERATIVE VITREORETINOPATHY BY HC-HA/PTX3, JPN6020014987, 2015, ISSN: 0004259318 *
THE JOURNAL OF BIOLOGICA_CHEMISTRY, vol. 289, no. 19, JPN6020014989, 2014, pages 13531 - 13542, ISSN: 0004259319 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023519954A (ja) * 2020-04-03 2023-05-15 ティッシュテック，インク． 眼表面障害の処置のための臍帯生成物の使用方法
JP2023546994A (ja) * 2020-10-26 2023-11-08 バイオティシュー ホールディングス インク． 胎児支持組織を処理する方法

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