CA2984443A1 - Compositions and methods for preventing the proliferation and epithelial-mesenchymal transition of epithelial cells - Google Patents

Compositions and methods for preventing the proliferation and epithelial-mesenchymal transition of epithelial cells Download PDF

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Publication number
CA2984443A1
CA2984443A1 CA2984443A CA2984443A CA2984443A1 CA 2984443 A1 CA2984443 A1 CA 2984443A1 CA 2984443 A CA2984443 A CA 2984443A CA 2984443 A CA2984443 A CA 2984443A CA 2984443 A1 CA2984443 A1 CA 2984443A1
Authority
CA
Canada
Prior art keywords
composition
ptx3
fetal support
support tissue
injection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2984443A
Other languages
English (en)
French (fr)
Inventor
Scheffer Tseng
Ek Kia Tan
Hua He
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BioTissue Holdings Inc
Original Assignee
TissueTech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TissueTech Inc filed Critical TissueTech Inc
Publication of CA2984443A1 publication Critical patent/CA2984443A1/en
Abandoned legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/50Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/51Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA2984443A 2015-05-20 2016-05-20 Compositions and methods for preventing the proliferation and epithelial-mesenchymal transition of epithelial cells Abandoned CA2984443A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562164281P 2015-05-20 2015-05-20
US62/164,281 2015-05-20
PCT/US2016/033558 WO2016187555A1 (en) 2015-05-20 2016-05-20 Compositions and methods for preventing the proliferation and epithelial-mesenchymal transition of epithelial cells

Publications (1)

Publication Number Publication Date
CA2984443A1 true CA2984443A1 (en) 2016-11-24

Family

ID=57320923

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2984443A Abandoned CA2984443A1 (en) 2015-05-20 2016-05-20 Compositions and methods for preventing the proliferation and epithelial-mesenchymal transition of epithelial cells

Country Status (8)

Country Link
US (3) US10342831B2 (https=)
EP (1) EP3297645A4 (https=)
JP (1) JP2018516869A (https=)
CN (1) CN107847526A (https=)
CA (1) CA2984443A1 (https=)
HK (1) HK1250940A1 (https=)
TW (1) TWI720984B (https=)
WO (1) WO2016187555A1 (https=)

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EP2897625B1 (en) 2012-09-10 2019-10-23 Wake Forest University Health Sciences Amniotic membrane and its use in wound healing and tissue engineering constructs
TW201603818A (zh) 2014-06-03 2016-02-01 組織科技股份有限公司 組成物及方法
US12083245B2 (en) 2014-10-02 2024-09-10 Wake Forest University Health Sciences Amniotic membrane powder and its use in wound healing and tissue engineering constructs
WO2016138025A2 (en) 2015-02-23 2016-09-01 Tissuetech, Inc. Apparatuses and methods for treating ophthalmic diseases and disorders
TWI720984B (zh) 2015-05-20 2021-03-11 美商帝聖工業公司 用於防止上皮細胞增生及上皮-間質轉移之組合物及方法
DK3429689T3 (da) * 2016-03-14 2022-01-31 Plakous Therapeutics Inc Acellulære placentapræparater
US11285177B2 (en) 2018-01-03 2022-03-29 Globus Medical, Inc. Allografts containing viable cells and methods thereof
EP3876963A4 (en) * 2018-11-07 2022-08-17 Tissuetech, Inc. PROCEDURE FOR CELL REPROGRAMMING
JP7684908B2 (ja) * 2019-04-16 2025-05-28 ライフネット ヘルス 出産組織由来の生成物並びにその調製及び使用
CN111019884B (zh) * 2019-12-31 2022-01-07 上海赛比曼生物科技有限公司 一种抑制人羊膜上皮细胞上皮间质转化的方法
EP4103592A4 (en) * 2020-02-12 2024-01-10 BioTissue Holdings Inc. METHODS OF DESTRUCTING OR INHIBITING THE GROWTH OF CANCER CELLS
CN115697265A (zh) * 2020-04-03 2023-02-03 组织技术公司 使用脐带产物治疗眼部表面病症的方法
WO2021226060A1 (en) * 2020-05-04 2021-11-11 Genesis Biologics, Inc. Formulations of hyaluronic acid and amniotic or gestational fluid, and uses of the same
KR20230119117A (ko) * 2020-10-26 2023-08-16 바이오티슈 홀딩스 인코포레이티드 태아 지지 조직의 처리 방법
US20220280473A1 (en) * 2021-03-02 2022-09-08 Auckland Uniservices Limited Compositions and methods for modulating epithelial-mesenchymal transition
WO2023211823A1 (en) * 2022-04-25 2023-11-02 Biotissue Holdings Inc. Compositions and methods relating to pooled fetal support tissue
CN115804665A (zh) * 2022-12-13 2023-03-17 南昌大学附属眼科医院 一种tpvr动物模型的建立方法

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