TWI623534B - 吡啶－４－基衍生物 - Google Patents
吡啶－４－基衍生物 Download PDFInfo
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- TWI623534B TWI623534B TW103109288A TW103109288A TWI623534B TW I623534 B TWI623534 B TW I623534B TW 103109288 A TW103109288 A TW 103109288A TW 103109288 A TW103109288 A TW 103109288A TW I623534 B TWI623534 B TW I623534B
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| EP2943485B1 (en) | 2013-01-14 | 2017-09-20 | Incyte Holdings Corporation | Bicyclic aromatic carboxamide compounds useful as pim kinase inhibitors |
| HUE050215T2 (hu) | 2013-01-15 | 2020-11-30 | Incyte Holdings Corp | Pim kináz inhibitorokként hasznos tiazolkarboxamid és piridinkarboxamid vegyületek |
| TW201605866A (zh) | 2013-08-23 | 2016-02-16 | 英塞特公司 | 可用作ｐｉｍ激酶抑制劑之呋喃并－及噻吩并－吡啶甲醯胺化合物 |
| WO2016010897A1 (en) | 2014-07-14 | 2016-01-21 | Incyte Corporation | Bicyclic heteroaromatic carboxamide compounds useful as pim kinase inhibitors |
| US9580418B2 (en) | 2014-07-14 | 2017-02-28 | Incyte Corporation | Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors |
| MY192358A (en) | 2015-05-20 | 2022-08-17 | Idorsia Pharmaceuticals Ltd | Crystalline form of the compound (s)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propane-1,2-diol |
| US9540347B2 (en) | 2015-05-29 | 2017-01-10 | Incyte Corporation | Pyridineamine compounds useful as Pim kinase inhibitors |
| WO2017004610A1 (en) * | 2015-07-02 | 2017-01-05 | Exelixis, Inc. | Tercyclic s1p3-sparing, s1p1 receptor agonists |
| TWI734699B (zh) | 2015-09-09 | 2021-08-01 | 美商英塞特公司 | Ｐｉｍ激酶抑制劑之鹽 |
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| WO2019113487A1 (en) | 2017-12-08 | 2019-06-13 | Incyte Corporation | Low dose combination therapy for treatment of myeloproliferative neoplasms |
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| AU2007292992B2 (en) | 2006-09-08 | 2013-01-10 | Actelion Pharmaceuticals Ltd | Pyridin-3-yl derivatives as immunomodulating agents |
| ES2393412T3 (es) | 2006-09-21 | 2012-12-21 | Actelion Pharmaceuticals Ltd. | Derivados de fenilo y su uso como inmunomoduladores |
| SI2125797T1 (sl) | 2007-03-16 | 2014-03-31 | Actelion Pharmaceuticals Ltd. | Derivati amino-piridina kot agonisti receptorja s1p1/edg1 |
| ES2361463T3 (es) | 2007-08-17 | 2011-06-17 | Actelion Pharmaceuticals Ltd. | Derivados de piridina como moduladores del receptor s1p1/edg1. |
| EP2193125B1 (en) | 2007-10-04 | 2017-01-11 | Merck Serono S.A. | Oxadiazole derivatives |
| EP2217594B1 (en) | 2007-11-01 | 2014-01-08 | Actelion Pharmaceuticals Ltd. | Novel pyrimidine derivatives |
| JP2011513385A (ja) | 2008-03-06 | 2011-04-28 | アクテリオン ファーマシューティカルズ リミテッド | 新規なピリミジン−ピリジン誘導体 |
| CA2714665A1 (en) | 2008-03-06 | 2009-09-11 | Actelion Pharmaceuticals Ltd | Pyridine compounds |
| CA2715317A1 (en) | 2008-03-07 | 2009-09-11 | Actelion Pharmaceuticals Ltd | Novel aminomethyl benzene derivatives |
| HRP20130641T1 (en) | 2008-03-07 | 2013-08-31 | Actelion Pharmaceuticals Ltd. | Pyridin-2-yl derivatives as immunomodulating agents |
| EP2913326B1 (en) * | 2008-05-14 | 2020-07-15 | The Scripps Research Institute | Novel modulators of sphingosine phosphate receptors |
| AR075781A1 (es) | 2009-03-03 | 2011-04-27 | Merck Serono Sa | Derivados de oxadiazol piridina como agonistas del receptor s1p1/edg1 y un metodo para su preparacion. |
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| TW201120016A (en) | 2009-12-08 | 2011-06-16 | Abbott Lab | Novel oxadiazole compounds |
| UA109804C2 (xx) | 2011-01-19 | 2015-10-12 | 2-метоксипіридин-4-ільні похідні |
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