TWI623534B - 吡啶－４－基衍生物 - Google Patents
吡啶－４－基衍生物 Download PDFInfo
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- TWI623534B TWI623534B TW103109288A TW103109288A TWI623534B TW I623534 B TWI623534 B TW I623534B TW 103109288 A TW103109288 A TW 103109288A TW 103109288 A TW103109288 A TW 103109288A TW I623534 B TWI623534 B TW I623534B
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| US9200004B2 (en) | 2013-01-15 | 2015-12-01 | Incyte Holdings Corporation | Thiazolecarboxamides and pyridinecarboxamide compounds useful as Pim kinase inhibitors |
| PE20160532A1 (es) | 2013-08-23 | 2016-05-21 | Incyte Corp | Compuesto de carboxamida de furo y tienopiridina utiles como inhibidores de cinasas pim |
| US9822124B2 (en) | 2014-07-14 | 2017-11-21 | Incyte Corporation | Bicyclic heteroaromatic carboxamide compounds useful as Pim kinase inhibitors |
| US9580418B2 (en) | 2014-07-14 | 2017-02-28 | Incyte Corporation | Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors |
| PH12017502097B1 (en) | 2015-05-20 | 2023-05-05 | Idorsia Pharmaceuticals Ltd | Crystalline form of the compound (s)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propane-1,2-diol |
| WO2016196244A1 (en) | 2015-05-29 | 2016-12-08 | Incyte Corporation | Pyridineamine compounds useful as pim kinase inhibitors |
| WO2017004610A1 (en) * | 2015-07-02 | 2017-01-05 | Exelixis, Inc. | Tercyclic s1p3-sparing, s1p1 receptor agonists |
| AR105967A1 (es) | 2015-09-09 | 2017-11-29 | Incyte Corp | Sales de un inhibidor de pim quinasa |
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| TW201924683A (zh) | 2017-12-08 | 2019-07-01 | 美商英塞特公司 | 用於治療骨髓增生性贅瘤的低劑量組合療法 |
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| US8288554B2 (en) | 2006-09-08 | 2012-10-16 | Actelion Pharmaceuticals Ltd. | Pyridin-3-yl derivatives as immunomodulating agents |
| WO2008035239A1 (en) | 2006-09-21 | 2008-03-27 | Actelion Pharmaceuticals Ltd | Phenyl derivatives and their use as immunomodulators |
| ES2450750T3 (es) | 2007-03-16 | 2014-03-25 | Actelion Pharmaceuticals Ltd. | Derivados de amino-piridina como agonistas del receptor S1P1/EDG1 |
| ATE502938T1 (de) | 2007-08-17 | 2011-04-15 | Actelion Pharmaceuticals Ltd | Pyridinderivate als s1p1/edg1-rezeptormodulatoren |
| US8202865B2 (en) | 2007-10-04 | 2012-06-19 | Merck Serono Sa | Oxadiazole derivatives |
| AR069146A1 (es) | 2007-11-01 | 2009-12-30 | Actelion Pharmaceuticals Ltd | Derivados de pirimidina, composicion farmaceutica que los comprende y el uso de esta para el tratamiento de enfermedades relacionadas con la activacion del sistema inmunitario. |
| US20110046170A1 (en) | 2008-03-06 | 2011-02-24 | Martin Bolli | Novel pyrimidine-pyridine derivatives |
| JP5411877B2 (ja) | 2008-03-06 | 2014-02-12 | アクテリオン ファーマシューティカルズ リミテッド | ピリジン化合物 |
| AU2009220893A1 (en) | 2008-03-07 | 2009-09-11 | Actelion Pharmaceuticals Ltd | Novel aminomethyl benzene derivatives |
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| ES2549761T3 (es) * | 2008-05-14 | 2015-11-02 | The Scripps Research Institute | Nuevos moduladores de los receptores de esfingosina fosfato |
| ES2517265T3 (es) | 2009-03-03 | 2014-11-03 | Merck Serono S.A. | Derivados de oxadiazol piridina |
| DK2454255T3 (da) | 2009-07-16 | 2013-12-16 | Actelion Pharmaceuticals Ltd | Pyridin-4-ylderivater som s1p1/edg1-agonister |
| TW201120016A (en) | 2009-12-08 | 2011-06-16 | Abbott Lab | Novel oxadiazole compounds |
| TWI546300B (zh) | 2011-01-19 | 2016-08-21 | 艾克泰聯製藥有限公司 | ２－甲氧基－吡啶－４－基衍生物 |
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