PL2970236T3 - Pochodne pirydyn-4-ylowe - Google Patents

Pochodne pirydyn-4-ylowe

Info

Publication number
PL2970236T3
PL2970236T3 PL14715427T PL14715427T PL2970236T3 PL 2970236 T3 PL2970236 T3 PL 2970236T3 PL 14715427 T PL14715427 T PL 14715427T PL 14715427 T PL14715427 T PL 14715427T PL 2970236 T3 PL2970236 T3 PL 2970236T3
Authority
PL
Poland
Prior art keywords
pyridin
derivatives
Prior art date
Application number
PL14715427T
Other languages
English (en)
Inventor
Martin Bolli
Cyrille Lescop
Oliver Nayler
Beat Steiner
Original Assignee
Idorsia Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idorsia Pharmaceuticals Ltd filed Critical Idorsia Pharmaceuticals Ltd
Publication of PL2970236T3 publication Critical patent/PL2970236T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Transplantation (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
PL14715427T 2013-03-15 2014-03-14 Pochodne pirydyn-4-ylowe PL2970236T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13159482 2013-03-15
EP14715427.2A EP2970236B1 (en) 2013-03-15 2014-03-14 Pyridin-4-yl derivatives
PCT/IB2014/059794 WO2014141171A1 (en) 2013-03-15 2014-03-14 Pyridin-4-yl derivatives

Publications (1)

Publication Number Publication Date
PL2970236T3 true PL2970236T3 (pl) 2018-01-31

Family

ID=47877933

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14715427T PL2970236T3 (pl) 2013-03-15 2014-03-14 Pochodne pirydyn-4-ylowe

Country Status (33)

Country Link
US (1) US9617250B2 (pl)
EP (1) EP2970236B1 (pl)
JP (1) JP6387361B2 (pl)
KR (1) KR102212975B1 (pl)
CN (1) CN105189487B (pl)
AR (1) AR095523A1 (pl)
AU (1) AU2014229217B2 (pl)
BR (1) BR112015023161B1 (pl)
CA (1) CA2900910C (pl)
CL (1) CL2015002620A1 (pl)
CY (1) CY1119619T1 (pl)
DK (1) DK2970236T3 (pl)
EA (1) EA029309B1 (pl)
ES (1) ES2649475T3 (pl)
HR (1) HRP20171763T1 (pl)
HU (1) HUE035154T2 (pl)
IL (1) IL241363B (pl)
LT (1) LT2970236T (pl)
MA (1) MA38482B1 (pl)
MX (1) MX363545B (pl)
MY (1) MY173573A (pl)
NO (1) NO2970236T3 (pl)
NZ (1) NZ713080A (pl)
PH (1) PH12015502118A1 (pl)
PL (1) PL2970236T3 (pl)
PT (1) PT2970236T (pl)
SA (1) SA515361104B1 (pl)
SG (1) SG11201507227UA (pl)
SI (1) SI2970236T1 (pl)
TW (1) TWI623534B (pl)
UA (1) UA115357C2 (pl)
WO (1) WO2014141171A1 (pl)
ZA (1) ZA201507657B (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2649156T3 (es) 2013-01-14 2018-01-10 Incyte Holdings Corporation Compuestos bicíclicos de carboxamida aromática útiles como inhibidores de quinasas Pim
CA2897333C (en) 2013-01-15 2021-07-06 Incyte Corporation Thiazolecarboxamides and pyridinecarboxamide compounds useful as pim kinase inhibitors
CR20160135A (es) 2013-08-23 2016-08-05 Incyte Corp Compuestos de carboxamida de furo y tienopiridina útiles como inhibidores de cinasas pim
WO2016010897A1 (en) 2014-07-14 2016-01-21 Incyte Corporation Bicyclic heteroaromatic carboxamide compounds useful as pim kinase inhibitors
US9580418B2 (en) 2014-07-14 2017-02-28 Incyte Corporation Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors
PT3298008T (pt) 2015-05-20 2020-02-03 Idorsia Pharmaceuticals Ltd Forma cristalina do composto (s)-3-{4-[5-(2-ciclopentil-6- metoxi-piridin-4-il)-[1,2,4]oxadiazol-3-il]-2-etil-6-metilfenoxi}- propano-1,2¿diol
US9540347B2 (en) 2015-05-29 2017-01-10 Incyte Corporation Pyridineamine compounds useful as Pim kinase inhibitors
WO2017004610A1 (en) * 2015-07-02 2017-01-05 Exelixis, Inc. Tercyclic s1p3-sparing, s1p1 receptor agonists
TWI734699B (zh) 2015-09-09 2021-08-01 美商英塞特公司 Pim激酶抑制劑之鹽
TW201718546A (zh) 2015-10-02 2017-06-01 英塞特公司 適用作pim激酶抑制劑之雜環化合物
WO2019113487A1 (en) 2017-12-08 2019-06-13 Incyte Corporation Low dose combination therapy for treatment of myeloproliferative neoplasms

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991015583A1 (en) 1990-04-05 1991-10-17 The American National Red Cross A protein family related to immediate-early protein expressed by human endothelial cells during differentiation
EP1070080A4 (en) 1998-03-09 2004-12-29 Smithkline Beecham Corp HUMAN EDG-1c POLYNUCLEOTIDES AND POLYPEPTIDES AND THEIR APPLICATIONS
AU2003279915A1 (en) 2002-10-15 2004-05-04 Merck And Co., Inc. Process for making azetidine-3-carboxylic acid
KR101470659B1 (ko) * 2006-09-07 2014-12-08 액테리온 파마슈티칼 리미티드 면역조절제로서 피리딘-4-일 유도체
MX2009002234A (es) 2006-09-08 2009-03-16 Actelion Pharmaceuticals Ltd Derivados de piridin-3-il como agentes inmunomoduladores.
RU2442780C2 (ru) 2006-09-21 2012-02-20 Актелион Фармасьютиклз Лтд Фенильные производные и их применение в качестве иммуномодуляторов
DK2125797T3 (da) 2007-03-16 2014-02-10 Actelion Pharmaceuticals Ltd Aminopyridinderivater som s1p1/edg1-receptoragonister
NZ583957A (en) 2007-08-17 2011-09-30 Actelion Pharmaceuticals Ltd Pyridine derivatives as s1p1/edg1 receptor modulators
US8202865B2 (en) 2007-10-04 2012-06-19 Merck Serono Sa Oxadiazole derivatives
KR20100092473A (ko) 2007-11-01 2010-08-20 액테리온 파마슈티칼 리미티드 신규한 피리미딘 유도체
CA2714665A1 (en) 2008-03-06 2009-09-11 Actelion Pharmaceuticals Ltd Pyridine compounds
WO2009109907A1 (en) 2008-03-06 2009-09-11 Actelion Pharmaceuticals Ltd Novel pyrimidine-pyridine derivatives
JP5435745B2 (ja) 2008-03-07 2014-03-05 アクテリオン ファーマシューティカルズ リミテッド 免疫調節剤としてのピリジン−2−イル誘導体
CN102007107B (zh) 2008-03-07 2014-07-23 埃科特莱茵药品有限公司 氨甲基苯衍生物
PL2913326T3 (pl) * 2008-05-14 2020-11-16 The Scripps Research Institute Nowe modulatory receptorów fosforanu sfingozyny
EP2403849B1 (en) 2009-03-03 2014-07-16 Merck Serono S.A. Oxazole pyridine derivatives useful as S1P1 receptor agonists
JP5036923B1 (ja) 2009-07-16 2012-09-26 アクテリオン ファーマシューティカルズ リミテッド ピリジン−4−イル誘導体
TW201120016A (en) 2009-12-08 2011-06-16 Abbott Lab Novel oxadiazole compounds
EP2665720B1 (en) 2011-01-19 2015-06-10 Actelion Pharmaceuticals Ltd. 2-methoxy-pyridin-4-yl derivatives

Also Published As

Publication number Publication date
SG11201507227UA (en) 2015-10-29
AU2014229217B2 (en) 2017-12-14
MX2015012293A (es) 2015-12-16
EA029309B1 (ru) 2018-03-30
HK1220454A1 (en) 2017-05-05
TWI623534B (zh) 2018-05-11
MA38482B1 (fr) 2018-11-30
DK2970236T3 (en) 2017-10-16
LT2970236T (lt) 2017-11-10
UA115357C2 (uk) 2017-10-25
IL241363A0 (en) 2015-11-30
NZ713080A (en) 2020-06-26
TW201443044A (zh) 2014-11-16
KR102212975B1 (ko) 2021-02-05
PT2970236T (pt) 2017-11-30
HRP20171763T1 (hr) 2017-12-29
MY173573A (en) 2020-02-04
CL2015002620A1 (es) 2016-03-18
HUE035154T2 (en) 2018-05-02
JP6387361B2 (ja) 2018-09-05
AR095523A1 (es) 2015-10-21
US9617250B2 (en) 2017-04-11
ZA201507657B (en) 2022-08-31
MX363545B (es) 2019-03-27
CN105189487A (zh) 2015-12-23
ES2649475T3 (es) 2018-01-12
KR20150128947A (ko) 2015-11-18
WO2014141171A1 (en) 2014-09-18
IL241363B (en) 2018-11-29
EP2970236A1 (en) 2016-01-20
CA2900910C (en) 2021-03-30
EA201500931A1 (ru) 2016-03-31
CY1119619T1 (el) 2018-04-04
BR112015023161B1 (pt) 2022-11-16
EP2970236B1 (en) 2017-08-30
SI2970236T1 (sl) 2017-11-30
CN105189487B (zh) 2017-12-26
PH12015502118B1 (en) 2016-01-25
US20160031866A1 (en) 2016-02-04
BR112015023161A2 (pt) 2017-07-18
PH12015502118A1 (en) 2016-01-25
AU2014229217A1 (en) 2015-11-05
CA2900910A1 (en) 2014-09-18
BR112015023161A8 (pt) 2021-06-22
JP2016512227A (ja) 2016-04-25
NO2970236T3 (pl) 2018-01-27
MA38482A1 (fr) 2017-12-29
SA515361104B1 (ar) 2016-06-28

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