PT2970236T - Derivados de piridin-4-ilo - Google Patents

Derivados de piridin-4-ilo

Info

Publication number
PT2970236T
PT2970236T PT147154272T PT14715427T PT2970236T PT 2970236 T PT2970236 T PT 2970236T PT 147154272 T PT147154272 T PT 147154272T PT 14715427 T PT14715427 T PT 14715427T PT 2970236 T PT2970236 T PT 2970236T
Authority
PT
Portugal
Prior art keywords
pyridin
derivatives
Prior art date
Application number
PT147154272T
Other languages
English (en)
Inventor
Steiner Beat
Bolli Martin
Lescop Cyrille
Nayler Oliver
Original Assignee
Idorsia Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idorsia Pharmaceuticals Ltd filed Critical Idorsia Pharmaceuticals Ltd
Publication of PT2970236T publication Critical patent/PT2970236T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
PT147154272T 2013-03-15 2014-03-14 Derivados de piridin-4-ilo PT2970236T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13159482 2013-03-15

Publications (1)

Publication Number Publication Date
PT2970236T true PT2970236T (pt) 2017-11-30

Family

ID=47877933

Family Applications (1)

Application Number Title Priority Date Filing Date
PT147154272T PT2970236T (pt) 2013-03-15 2014-03-14 Derivados de piridin-4-ilo

Country Status (34)

Country Link
US (1) US9617250B2 (pt)
EP (1) EP2970236B1 (pt)
JP (1) JP6387361B2 (pt)
KR (1) KR102212975B1 (pt)
CN (1) CN105189487B (pt)
AR (1) AR095523A1 (pt)
AU (1) AU2014229217B2 (pt)
BR (1) BR112015023161B1 (pt)
CA (1) CA2900910C (pt)
CL (1) CL2015002620A1 (pt)
CY (1) CY1119619T1 (pt)
DK (1) DK2970236T3 (pt)
EA (1) EA029309B1 (pt)
ES (1) ES2649475T3 (pt)
HK (1) HK1220454A1 (pt)
HR (1) HRP20171763T1 (pt)
HU (1) HUE035154T2 (pt)
IL (1) IL241363B (pt)
LT (1) LT2970236T (pt)
MA (1) MA38482B1 (pt)
MX (1) MX363545B (pt)
MY (1) MY173573A (pt)
NO (1) NO2970236T3 (pt)
NZ (1) NZ713080A (pt)
PH (1) PH12015502118B1 (pt)
PL (1) PL2970236T3 (pt)
PT (1) PT2970236T (pt)
SA (1) SA515361104B1 (pt)
SG (1) SG11201507227UA (pt)
SI (1) SI2970236T1 (pt)
TW (1) TWI623534B (pt)
UA (1) UA115357C2 (pt)
WO (1) WO2014141171A1 (pt)
ZA (1) ZA201507657B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014110574A1 (en) 2013-01-14 2014-07-17 Incyte Corporation Bicyclic aromatic carboxamide compounds useful as pim kinase inhibitors
SG10201705662WA (en) 2013-01-15 2017-08-30 Incyte Corp Thiazolecarboxamides and pyridinecarboxamide compounds useful as pim kinase inhibitors
PE20160532A1 (es) 2013-08-23 2016-05-21 Incyte Corp Compuesto de carboxamida de furo y tienopiridina utiles como inhibidores de cinasas pim
US9580418B2 (en) 2014-07-14 2017-02-28 Incyte Corporation Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors
WO2016010897A1 (en) 2014-07-14 2016-01-21 Incyte Corporation Bicyclic heteroaromatic carboxamide compounds useful as pim kinase inhibitors
CN114573574A (zh) 2015-05-20 2022-06-03 爱杜西亚药品有限公司 一种化合物的结晶形式
WO2016196244A1 (en) 2015-05-29 2016-12-08 Incyte Corporation Pyridineamine compounds useful as pim kinase inhibitors
WO2017004610A1 (en) * 2015-07-02 2017-01-05 Exelixis, Inc. Tercyclic s1p3-sparing, s1p1 receptor agonists
TWI734699B (zh) 2015-09-09 2021-08-01 美商英塞特公司 Pim激酶抑制劑之鹽
TW201718546A (zh) 2015-10-02 2017-06-01 英塞特公司 適用作pim激酶抑制劑之雜環化合物
US10596161B2 (en) 2017-12-08 2020-03-24 Incyte Corporation Low dose combination therapy for treatment of myeloproliferative neoplasms

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7686891A (en) 1990-04-05 1991-10-30 American National Red Cross, The A protein family related to immediate-early protein expressed by human endothelial cells during differentiation
WO1999046277A1 (en) 1998-03-09 1999-09-16 Smithkline Beecham Corporation HUMAN EDG-1c POLYNUCLEOTIDES AND POLYPEPTIDES AND METHODS OF USE
AU2003279915A1 (en) 2002-10-15 2004-05-04 Merck And Co., Inc. Process for making azetidine-3-carboxylic acid
AU2007292993B2 (en) 2006-09-07 2013-01-24 Idorsia Pharmaceuticals Ltd Pyridin-4-yl derivatives as immunomodulating agents
CA2661315C (en) * 2006-09-08 2015-11-24 Actelion Pharmaceuticals Ltd Pyridin-3-yl derivatives as immunomodulating agents
RU2442780C2 (ru) 2006-09-21 2012-02-20 Актелион Фармасьютиклз Лтд Фенильные производные и их применение в качестве иммуномодуляторов
DK2125797T3 (da) 2007-03-16 2014-02-10 Actelion Pharmaceuticals Ltd Aminopyridinderivater som s1p1/edg1-receptoragonister
SI2195311T1 (sl) 2007-08-17 2011-07-29 Actelion Pharmaceuticals Ltd Derivati piridina kot modulatorji receptorja s1p1/edg1
AU2008306885B2 (en) 2007-10-04 2013-12-05 Merck Serono S.A. Oxadiazole derivatives
AU2008320374A1 (en) 2007-11-01 2009-05-07 Actelion Pharmaceuticals Ltd Novel pyrimidine derivatives
ES2389042T3 (es) 2008-03-06 2012-10-22 Actelion Pharmaceuticals Ltd. Compuestos de piridina
JP2011513385A (ja) 2008-03-06 2011-04-28 アクテリオン ファーマシューティカルズ リミテッド 新規なピリミジン−ピリジン誘導体
SI2252609T1 (sl) 2008-03-07 2013-07-31 Actelion Pharmaceuticals Ltd. Derivati piridin-2-ila kot imunomodulacijska sredstva
US8410151B2 (en) 2008-03-07 2013-04-02 Actelion Pharmaceuticals Ltd Aminomethyl benzene derivatives
NZ589617A (en) * 2008-05-14 2012-06-29 Scripps Research Inst 3-(Inden-4-yl)-5-(phenyl)-1,2,4-oxadiazole and 3-(tetralin-5-yl)-5-(phenyl)-1,2,4-oxadiazole derivatives
US8791142B2 (en) 2009-03-03 2014-07-29 Merck Serono S.A. Oxazole pyridine derivatives useful as S1P1 receptor agonists
TWI410421B (zh) 2009-07-16 2013-10-01 Actelion Pharmaceuticals Ltd 吡啶-4-基衍生物
TW201120016A (en) 2009-12-08 2011-06-16 Abbott Lab Novel oxadiazole compounds
AU2012208325B2 (en) 2011-01-19 2016-12-22 Idorsia Pharmaceuticals Ltd 2-methoxy-pyridin-4-yl derivatives

Also Published As

Publication number Publication date
LT2970236T (lt) 2017-11-10
EP2970236B1 (en) 2017-08-30
NZ713080A (en) 2020-06-26
BR112015023161B1 (pt) 2022-11-16
TW201443044A (zh) 2014-11-16
AU2014229217B2 (en) 2017-12-14
BR112015023161A8 (pt) 2021-06-22
SA515361104B1 (ar) 2016-06-28
HK1220454A1 (zh) 2017-05-05
CL2015002620A1 (es) 2016-03-18
TWI623534B (zh) 2018-05-11
EA029309B1 (ru) 2018-03-30
CN105189487B (zh) 2017-12-26
CY1119619T1 (el) 2018-04-04
PH12015502118A1 (en) 2016-01-25
US20160031866A1 (en) 2016-02-04
WO2014141171A1 (en) 2014-09-18
NO2970236T3 (pt) 2018-01-27
HUE035154T2 (en) 2018-05-02
US9617250B2 (en) 2017-04-11
AU2014229217A1 (en) 2015-11-05
CA2900910C (en) 2021-03-30
JP2016512227A (ja) 2016-04-25
SG11201507227UA (en) 2015-10-29
ZA201507657B (en) 2022-08-31
MX2015012293A (es) 2015-12-16
EP2970236A1 (en) 2016-01-20
HRP20171763T1 (hr) 2017-12-29
KR102212975B1 (ko) 2021-02-05
ES2649475T3 (es) 2018-01-12
AR095523A1 (es) 2015-10-21
MY173573A (en) 2020-02-04
PL2970236T3 (pl) 2018-01-31
BR112015023161A2 (pt) 2017-07-18
MA38482B1 (fr) 2018-11-30
IL241363B (en) 2018-11-29
JP6387361B2 (ja) 2018-09-05
MA38482A1 (fr) 2017-12-29
DK2970236T3 (en) 2017-10-16
PH12015502118B1 (en) 2016-01-25
IL241363A0 (en) 2015-11-30
CN105189487A (zh) 2015-12-23
SI2970236T1 (sl) 2017-11-30
UA115357C2 (uk) 2017-10-25
KR20150128947A (ko) 2015-11-18
EA201500931A1 (ru) 2016-03-31
MX363545B (es) 2019-03-27
CA2900910A1 (en) 2014-09-18

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