SG10201705662WA - Thiazolecarboxamides and pyridinecarboxamide compounds useful as pim kinase inhibitors - Google Patents

Thiazolecarboxamides and pyridinecarboxamide compounds useful as pim kinase inhibitors

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Publication number
SG10201705662WA
SG10201705662WA SG10201705662WA SG10201705662WA SG10201705662WA SG 10201705662W A SG10201705662W A SG 10201705662WA SG 10201705662W A SG10201705662W A SG 10201705662WA SG 10201705662W A SG10201705662W A SG 10201705662WA SG 10201705662W A SG10201705662W A SG 10201705662WA
Authority
SG
Singapore
Prior art keywords
thiazolecarboxamides
kinase inhibitors
compounds useful
pim kinase
pyridinecarboxamide compounds
Prior art date
Application number
SG10201705662WA
Inventor
Chu-Biao Xue
Yun-Long Li
Hao Feng
Jun Pan
Anlai Wang
Ke Zhang
Wenqing Yao
Fenglei Zhang
Jincong Zhuo
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US201361752897P priority Critical
Priority to US201361790952P priority
Priority to US201361859118P priority
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of SG10201705662WA publication Critical patent/SG10201705662WA/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
SG10201705662WA 2013-01-15 2014-01-14 Thiazolecarboxamides and pyridinecarboxamide compounds useful as pim kinase inhibitors SG10201705662WA (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US201361752897P true 2013-01-15 2013-01-15
US201361790952P true 2013-03-15 2013-03-15
US201361859118P true 2013-07-26 2013-07-26

Publications (1)

Publication Number Publication Date
SG10201705662WA true SG10201705662WA (en) 2017-08-30

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Country Status (20)

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US (5) US9200004B2 (en)
EP (1) EP2945939A1 (en)
JP (1) JP6554037B2 (en)
KR (1) KR20150113019A (en)
CN (2) CN105051029B (en)
AR (1) AR094664A1 (en)
AU (2) AU2014207691B2 (en)
BR (1) BR112015016793A2 (en)
CA (1) CA2897333A1 (en)
CL (1) CL2015001985A1 (en)
CR (1) CR20150412A (en)
EA (1) EA201591339A1 (en)
HK (1) HK1216424A1 (en)
IL (1) IL239886D0 (en)
MX (1) MX2015009057A (en)
PE (1) PE14482015A1 (en)
PH (1) PH12015501567A1 (en)
SG (2) SG11201505347VA (en)
TW (1) TWI662030B (en)
WO (1) WO2014113388A1 (en)

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