HRP20171763T1 - Derivati piridin-4-ila - Google Patents
Derivati piridin-4-ila Download PDFInfo
- Publication number
- HRP20171763T1 HRP20171763T1 HRP20171763TT HRP20171763T HRP20171763T1 HR P20171763 T1 HRP20171763 T1 HR P20171763T1 HR P20171763T T HRP20171763T T HR P20171763TT HR P20171763 T HRP20171763 T HR P20171763T HR P20171763 T1 HRP20171763 T1 HR P20171763T1
- Authority
- HR
- Croatia
- Prior art keywords
- compound according
- ethyl
- hydroxyacetamide
- oxadiazol
- hydroxypropyl
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Otolaryngology (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Transplantation (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epidemiology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13159482 | 2013-03-15 | ||
| EP14715427.2A EP2970236B1 (en) | 2013-03-15 | 2014-03-14 | Pyridin-4-yl derivatives |
| PCT/IB2014/059794 WO2014141171A1 (en) | 2013-03-15 | 2014-03-14 | Pyridin-4-yl derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20171763T1 true HRP20171763T1 (hr) | 2017-12-29 |
Family
ID=47877933
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20171763TT HRP20171763T1 (hr) | 2013-03-15 | 2014-03-14 | Derivati piridin-4-ila |
Country Status (33)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2943485B1 (en) | 2013-01-14 | 2017-09-20 | Incyte Holdings Corporation | Bicyclic aromatic carboxamide compounds useful as pim kinase inhibitors |
| AU2014207691B2 (en) | 2013-01-15 | 2018-08-30 | Incyte Holdings Corporation | Thiazolecarboxamides and pyridinecarboxamide compounds useful as Pim kinase inhibitors |
| EP3036238A1 (en) | 2013-08-23 | 2016-06-29 | Incyte Corporation | Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors |
| US9580418B2 (en) | 2014-07-14 | 2017-02-28 | Incyte Corporation | Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors |
| US9822124B2 (en) | 2014-07-14 | 2017-11-21 | Incyte Corporation | Bicyclic heteroaromatic carboxamide compounds useful as Pim kinase inhibitors |
| TWI711609B (zh) | 2015-05-20 | 2020-12-01 | 瑞士商愛杜西亞製藥有限公司 | 結晶形式 |
| US9540347B2 (en) | 2015-05-29 | 2017-01-10 | Incyte Corporation | Pyridineamine compounds useful as Pim kinase inhibitors |
| WO2017004610A1 (en) * | 2015-07-02 | 2017-01-05 | Exelixis, Inc. | Tercyclic s1p3-sparing, s1p1 receptor agonists |
| TWI734699B (zh) | 2015-09-09 | 2021-08-01 | 美商英塞特公司 | Ｐｉｍ激酶抑制劑之鹽 |
| WO2017059251A1 (en) | 2015-10-02 | 2017-04-06 | Incyte Corporation | Heterocyclic compounds useful as pim kinase inhibitors |
| TW201924683A (zh) | 2017-12-08 | 2019-07-01 | 美商英塞特公司 | 用於治療骨髓增生性贅瘤的低劑量組合療法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7686891A (en) | 1990-04-05 | 1991-10-30 | American National Red Cross, The | A protein family related to immediate-early protein expressed by human endothelial cells during differentiation |
| EP1070080A4 (en) | 1998-03-09 | 2004-12-29 | Smithkline Beecham Corp | HUMAN EDG-1c POLYNUCLEOTIDES AND POLYPEPTIDES AND THEIR APPLICATIONS |
| WO2004035538A1 (en) | 2002-10-15 | 2004-04-29 | Merck & Co., Inc. | Process for making azetidine-3-carboxylic acid |
| BRPI0716171B8 (pt) * | 2006-09-07 | 2021-05-25 | Actelion Pharmaceuticals Ltd | composto, composição farmacêutica e uso de um composto |
| JP5253400B2 (ja) | 2006-09-08 | 2013-07-31 | アクテリオン ファーマシューティカルズ リミテッド | 免疫調節薬としてのピリジン−３−イル誘導体 |
| CN101522645B (zh) | 2006-09-21 | 2013-01-09 | 埃科特莱茵药品有限公司 | 苯衍生物及其免疫调节剂的用途 |
| NZ580454A (en) | 2007-03-16 | 2011-05-27 | Actelion Pharmaceuticals Ltd | Amino- pyridine derivatives as s1p1 /edg1 receptor agonists |
| ATE502938T1 (de) | 2007-08-17 | 2011-04-15 | Actelion Pharmaceuticals Ltd | Pyridinderivate als s1p1/edg1-rezeptormodulatoren |
| US8202865B2 (en) | 2007-10-04 | 2012-06-19 | Merck Serono Sa | Oxadiazole derivatives |
| CN101970430B (zh) | 2007-11-01 | 2013-05-08 | 埃科特莱茵药品有限公司 | 嘧啶衍生物 |
| EP2262799B1 (en) | 2008-03-06 | 2012-07-04 | Actelion Pharmaceuticals Ltd. | Pyridine compounds |
| WO2009109907A1 (en) | 2008-03-06 | 2009-09-11 | Actelion Pharmaceuticals Ltd | Novel pyrimidine-pyridine derivatives |
| KR20100125380A (ko) | 2008-03-07 | 2010-11-30 | 액테리온 파마슈티칼 리미티드 | 신규한 아미노메틸 벤젠 유도체 |
| RU2494099C2 (ru) | 2008-03-07 | 2013-09-27 | Актелион Фармасьютиклз Лтд | Пиридин-2-ильные производные в качестве иммуномодулирующих агентов |
| ES2549761T3 (es) * | 2008-05-14 | 2015-11-02 | The Scripps Research Institute | Nuevos moduladores de los receptores de esfingosina fosfato |
| AR075781A1 (es) | 2009-03-03 | 2011-04-27 | Merck Serono Sa | Derivados de oxadiazol piridina como agonistas del receptor s1p1/edg1 y un metodo para su preparacion. |
| NZ598173A (en) | 2009-07-16 | 2014-01-31 | Actelion Pharmaceuticals Ltd | Pyridin-4-yl derivatives |
| TW201120016A (en) | 2009-12-08 | 2011-06-16 | Abbott Lab | Novel oxadiazole compounds |
| SI2665720T1 (sl) | 2011-01-19 | 2015-08-31 | Actelion Pharmaceuticals Ltd. | Derivati 2-metoksi-piridin-4-ila |
-
2014
- 2014-03-14 NO NO14715427A patent/NO2970236T3/no unknown
- 2014-03-14 NZ NZ713080A patent/NZ713080A/en not_active IP Right Cessation
- 2014-03-14 DK DK14715427.2T patent/DK2970236T3/en active
- 2014-03-14 AR ARP140101131A patent/AR095523A1/es active IP Right Grant
- 2014-03-14 CN CN201480016238.1A patent/CN105189487B/zh not_active Expired - Fee Related
- 2014-03-14 KR KR1020157028486A patent/KR102212975B1/ko not_active Expired - Fee Related
- 2014-03-14 SI SI201430428T patent/SI2970236T1/sl unknown
- 2014-03-14 PT PT147154272T patent/PT2970236T/pt unknown
- 2014-03-14 UA UAA201510003A patent/UA115357C2/uk unknown
- 2014-03-14 SG SG11201507227UA patent/SG11201507227UA/en unknown
- 2014-03-14 LT LTEP14715427.2T patent/LT2970236T/lt unknown
- 2014-03-14 HU HUE14715427A patent/HUE035154T2/en unknown
- 2014-03-14 US US14/777,444 patent/US9617250B2/en active Active
- 2014-03-14 CA CA2900910A patent/CA2900910C/en active Active
- 2014-03-14 HR HRP20171763TT patent/HRP20171763T1/hr unknown
- 2014-03-14 JP JP2015562523A patent/JP6387361B2/ja not_active Expired - Fee Related
- 2014-03-14 PL PL14715427T patent/PL2970236T3/pl unknown
- 2014-03-14 TW TW103109288A patent/TWI623534B/zh not_active IP Right Cessation
- 2014-03-14 ES ES14715427.2T patent/ES2649475T3/es active Active
- 2014-03-14 EA EA201500931A patent/EA029309B1/ru not_active IP Right Cessation
- 2014-03-14 BR BR112015023161-6A patent/BR112015023161B1/pt not_active IP Right Cessation
- 2014-03-14 EP EP14715427.2A patent/EP2970236B1/en active Active
- 2014-03-14 MX MX2015012293A patent/MX363545B/es unknown
- 2014-03-14 MY MYPI2015703154A patent/MY173573A/en unknown
- 2014-03-14 WO PCT/IB2014/059794 patent/WO2014141171A1/en not_active Ceased
- 2014-03-14 MA MA38482A patent/MA38482B1/fr unknown
- 2014-03-14 AU AU2014229217A patent/AU2014229217B2/en not_active Ceased
-
2015
- 2015-09-09 IL IL241363A patent/IL241363B/en active IP Right Grant
- 2015-09-11 CL CL2015002620A patent/CL2015002620A1/es unknown
- 2015-09-14 SA SA515361104A patent/SA515361104B1/ar unknown
- 2015-09-14 PH PH12015502118A patent/PH12015502118B1/en unknown
- 2015-10-14 ZA ZA2015/07657A patent/ZA201507657B/en unknown
-
2017
- 2017-11-24 CY CY20171101239T patent/CY1119619T1/el unknown
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