TWI495644B - 營養層細胞表面抗原（Ｔｒｏｐ－２）之專一性抗體類及彼等之用途 - Google Patents

營養層細胞表面抗原（Ｔｒｏｐ－２）之專一性抗體類及彼等之用途 Download PDF

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TWI495644B
TWI495644B TW101141373A TW101141373A TWI495644B TW I495644 B TWI495644 B TW I495644B TW 101141373 A TW101141373 A TW 101141373A TW 101141373 A TW101141373 A TW 101141373A TW I495644 B TWI495644 B TW I495644B
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antibody
seq
sequence
trop
conjugate
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TW101141373A
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Chinese (zh)
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TW201333036A (zh
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Shu-Hui Liu
Wei-Hsien Ho
Pavel Strop
Magdalena Grazyna Dorywalska
Arvind Rajpal
David Louis Shelton
Thomas-Toan Tran
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Rinat Neuroscience Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
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    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
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TW101141373A 2011-11-11 2012-11-07 營養層細胞表面抗原（Ｔｒｏｐ－２）之專一性抗體類及彼等之用途 TWI495644B (zh)

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US201161559015P 2011-11-11 2011-11-11
US201261640641P 2012-04-30 2012-04-30
US201261717288P 2012-10-23 2012-10-23

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TWI495644B true TWI495644B (zh) 2015-08-11

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KR (1) KR20140091040A (OSRAM)
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AU (1) AU2012335205A1 (OSRAM)
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