TWI461411B - 製備５－鹵烷基－４，５－二氫異唑衍生物之方法 - Google Patents

製備５－鹵烷基－４，５－二氫異唑衍生物之方法 Download PDF

Info

Publication number
TWI461411B
TWI461411B TW97129034A TW97129034A TWI461411B TW I461411 B TWI461411 B TW I461411B TW 97129034 A TW97129034 A TW 97129034A TW 97129034 A TW97129034 A TW 97129034A TW I461411 B TWI461411 B TW I461411B
Authority
TW
Taiwan
Prior art keywords
group
alkyl
haloalkyl
halogen
independently
Prior art date
Application number
TW97129034A
Other languages
English (en)
Chinese (zh)
Other versions
TW200914429A (en
Inventor
Gary David Annis
Brenton Todd Smith
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of TW200914429A publication Critical patent/TW200914429A/zh
Application granted granted Critical
Publication of TWI461411B publication Critical patent/TWI461411B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/835—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups having unsaturation outside an aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/38—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups having unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
TW97129034A 2007-08-17 2008-07-31 製備５－鹵烷基－４，５－二氫異唑衍生物之方法 TWI461411B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96511507P 2007-08-17 2007-08-17
US4345908P 2008-04-09 2008-04-09
US8045408P 2008-07-14 2008-07-14

Publications (2)

Publication Number Publication Date
TW200914429A TW200914429A (en) 2009-04-01
TWI461411B true TWI461411B (zh) 2014-11-21

Family

ID=40350174

Family Applications (3)

Application Number Title Priority Date Filing Date
TW97129034A TWI461411B (zh) 2007-08-17 2008-07-31 製備５－鹵烷基－４，５－二氫異唑衍生物之方法
TW106102361A TWI649303B (zh) 2007-08-17 2008-07-31 製備４-乙醯基-ｎ-〔２-側氧基-２-〔（２，２，２-三氟乙基）胺基〕乙基〕-１-萘甲醯胺之化合物及方法
TW103118216A TWI600639B (zh) 2007-08-17 2008-07-31 製備５-鹵烷基-４，５-二氫異唑衍生物之化合物

Family Applications After (2)

Application Number Title Priority Date Filing Date
TW106102361A TWI649303B (zh) 2007-08-17 2008-07-31 製備４-乙醯基-ｎ-〔２-側氧基-２-〔（２，２，２-三氟乙基）胺基〕乙基〕-１-萘甲醯胺之化合物及方法
TW103118216A TWI600639B (zh) 2007-08-17 2008-07-31 製備５-鹵烷基-４，５-二氫異唑衍生物之化合物

Country Status (19)

Country Link
US (2) US8217180B2 (cg-RX-API-DMAC7.html)
EP (1) EP2176244B1 (cg-RX-API-DMAC7.html)
JP (2) JP5965102B2 (cg-RX-API-DMAC7.html)
KR (2) KR101597839B1 (cg-RX-API-DMAC7.html)
CN (2) CN105693646A (cg-RX-API-DMAC7.html)
AR (1) AR067948A1 (cg-RX-API-DMAC7.html)
AU (1) AU2008289321B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0814153B8 (cg-RX-API-DMAC7.html)
CA (1) CA2693067C (cg-RX-API-DMAC7.html)
CO (1) CO6260136A2 (cg-RX-API-DMAC7.html)
ES (1) ES2587386T3 (cg-RX-API-DMAC7.html)
IL (1) IL203174A (cg-RX-API-DMAC7.html)
MX (2) MX337588B (cg-RX-API-DMAC7.html)
MY (2) MY176115A (cg-RX-API-DMAC7.html)
PT (1) PT2176244T (cg-RX-API-DMAC7.html)
RU (1) RU2536039C2 (cg-RX-API-DMAC7.html)
TW (3) TWI461411B (cg-RX-API-DMAC7.html)
WO (1) WO2009025983A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA201000214B (cg-RX-API-DMAC7.html)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102558082B (zh) 2004-03-05 2015-09-30 日产化学工业株式会社 异噁唑啉取代苯甲酰胺化合物的制备中间体
TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
JP5473906B2 (ja) 2007-06-13 2014-04-16 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー イソキサゾリン殺虫剤
TWI430995B (zh) * 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
CA2971008A1 (en) 2007-06-27 2008-12-31 E. I. Du Pont De Nemours And Company Animal pest control method
EP2172462A4 (en) * 2007-06-27 2010-12-15 Nissan Chemical Ind Ltd METHOD FOR PRODUCING A 3-HYDROXYPROPAN-1-ON COMPOUND, METHOD FOR PRODUCING A 2-PROPENE-1-ON COMPOUND, AND METHOD FOR PRODUCING AN ISOXAZOLINE COMPOUND
TWI461411B (zh) 2007-08-17 2014-11-21 Du Pont 製備５－鹵烷基－４，５－二氫異唑衍生物之方法
WO2009045999A1 (en) * 2007-10-03 2009-04-09 E. I. Du Pont De Nemours And Company Naphthalene isoxazoline compounds for control of invertebrate pests
TWI455919B (zh) 2008-04-09 2014-10-11 Du Pont 製備３－三氟甲基查耳酮（ｃｈａｌｃｏｎｅ）之方法
WO2010003877A1 (en) 2008-07-09 2010-01-14 Basf Se Pesticidal mixtures comprising isoxazoline compounds ii
CN102088856B (zh) 2008-07-09 2015-11-25 巴斯夫欧洲公司 包含异*唑啉化合物的杀虫活性混合物i
ES2434734T3 (es) 2008-08-22 2013-12-17 Syngenta Participations Ag Compuestos insecticidas
MX2011001851A (es) 2008-08-22 2011-03-21 Syngenta Participations Ag Compuestos insecticidas.
CA2732217A1 (en) 2008-09-04 2010-03-11 Peter Renold Insecticidal compounds
EP2382196B1 (en) 2008-12-23 2015-08-12 Basf Se Imine compounds for combating invertebrate pests
AU2009331664A1 (en) 2008-12-23 2011-07-14 Basf Se Substituted amidine compounds for combating animal pests
US20120030841A1 (en) * 2009-04-01 2012-02-02 Basf Se Isoxazoline compounds for combating invertebrate pests
PL3560923T3 (pl) 2009-12-17 2021-12-27 Boehringer Ingelheim Animal Health USA Inc. Dihydroazolowe kompozycje przeciwpasożytnicze i kompozycje je zawierające
WO2011092287A1 (en) 2010-02-01 2011-08-04 Basf Se Substituted ketonic isoxazoline compounds and derivatives for combating animal pests
PH12012502333A1 (en) * 2010-05-27 2015-02-04 Corteva Agriscience Llc Crystalline form of 4- [5 - [3 -chloro-5 - (trifluoromethyl) phenyl] -4, 5 - dihydro - 5 - (trifluoromethyl) -3 - isoxazolyl] -n- [2-0x0-2- [ ( 2, 2, 2 - trifluoroethyl) amino] ethyl] -1- naphthalenecarboxamide
UY33403A (es) 2010-06-17 2011-12-30 Novartis Ag Compuestos orgánicos con novedosas isoxazolinas, sus n-óxidos, s-óxidos y sales
AU2011306489B2 (en) 2010-09-24 2015-11-05 Zoetis Services Llc Isoxazoline oximes as antiparasitic agents
MX341417B (es) 2010-09-27 2016-08-19 E I Du Pont De Nemours And Company * Metodo para preparar 2-amino-n-(2,2,2-trifluoroetil) acetamida.
MX2013009211A (es) 2011-02-10 2013-08-29 Novartis Ag Derivados de isoxazolina para controlar plagas de invertebrados.
AU2012224521B2 (en) 2011-03-10 2015-10-29 Novartis Tiergesundheit Ag Isoxazole derivatives
US9126995B2 (en) 2011-11-08 2015-09-08 Nissan Chemical Industries, Ltd. Method for catalytic asymmetric synthesis of optically active isoxazoline compound and optically active isoxazoline compound
AU2012356947A1 (en) 2011-12-23 2014-07-10 Basf Se Isothiazoline compounds for combating invertebrate pests
HRP20181448T1 (hr) 2012-11-20 2018-11-02 Merial, Inc. Antihelmintski spojevi i sastavi te postupak za njihovu uporabu
ES2905848T3 (es) 2013-11-01 2022-04-12 Boehringer Ingelheim Animal Health Usa Inc Compuestos de isoxazolina antiparasitarios y plaguicidas
ES2842592T3 (es) 2014-05-19 2021-07-14 Boehringer Ingelheim Animal Health Usa Inc Compuestos antihelmínticos
EP3211998B1 (en) 2014-10-31 2021-04-07 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal composition comprising fipronil
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
EA201892245A1 (ru) 2016-04-06 2019-07-31 Мериал, Инк. Способ получения энантиомерно-обогащенных изоксазолиновых соединений - кристаллический толуольный сольват(s)-афоксоланера
CN110381738B (zh) 2016-10-14 2021-07-16 勃林格殷格翰动物保健美国公司 农药的和杀寄生物的乙烯基异噁唑啉化合物
EA201992360A1 (ru) * 2017-04-05 2020-09-02 БЁРИНГЕР ИНГЕЛЬХАЙМ ЭНИМАЛ ХЕЛТ ЮЭсЭй ИНК. Кристаллические формы (s)-афоксоланера
CN111194316A (zh) 2017-08-14 2020-05-22 勃林格殷格翰动物保健美国公司 农药的和杀寄生物的吡唑-异噁唑啉化合物
CN118084940A (zh) 2018-02-13 2024-05-28 吉利德科学公司 Pd-1/pd-l1抑制剂
AU2019255750B2 (en) 2018-04-19 2021-10-21 Gilead Sciences, Inc. PD-1/PD-L1 inhibitors
EP3789382B1 (en) 2018-04-27 2023-07-05 Kumiai Chemical Industry Co., Ltd. Production method for 5,5-di-substituted-4,5-dihydroisoxazole
PE20210642A1 (es) 2018-07-13 2021-03-23 Gilead Sciences Inc Inhibidores de pd-1/pd-l1
CN112955435B (zh) 2018-10-24 2024-09-06 吉利德科学公司 Pd-1/pd-l1抑制剂
EP4041431A1 (en) 2019-10-08 2022-08-17 Donaldson Company, Inc. Filter media layers including mixed diameter fine fibers
MX2022007455A (es) 2019-12-18 2022-08-15 Elanco Tiergesundheit Ag Derivados de isoxazolina como plaguicidas.
AU2021280287A1 (en) 2020-05-27 2023-01-05 Axial Therapeutics, Inc. TLR2 modulator compounds, pharmaceutical compositions and uses thereof
CN117098541A (zh) 2020-11-25 2023-11-21 阿卡格拉医药公司 用于递送核酸的脂质纳米粒及相关使用方法
US20250091998A1 (en) * 2021-08-01 2025-03-20 Zenfold Sustainable Technologies Private Limited A process for the preparation of carbamoyl benzamide phenyl isoxazoline class drug/s and its intermediates
CN115710185B (zh) * 2021-08-23 2024-05-03 中国石油化工股份有限公司 利用金属碳化物催化剂生产甲胺的方法
CA3256897A1 (en) 2022-05-25 2023-11-30 Akagera Medicines, Inc. Lipid nanoparticles for the administration of nucleic acids and their methods of use
CN116903488B (zh) * 2022-11-25 2023-12-15 济南久隆医药科技有限公司 一种阿福拉纳的合成方法
CN115772091B (zh) * 2023-01-05 2023-06-23 济南久隆医药科技有限公司 一种2-氨基-n-(2,2,2-三氟乙基)乙酰胺的合成方法
CN119899156A (zh) * 2023-10-27 2025-04-29 华北制药集团动物保健品有限责任公司 一种阿福拉纳的制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005085216A1 (ja) * 2004-03-05 2005-09-15 Nissan Chemical Industries, Ltd. イソキサゾリン置換ベンズアミド化合物及び有害生物防除剤
US20050250822A1 (en) * 2002-08-26 2005-11-10 Takeshi Mita Substituted benzanilide compound and noxious organism controlling agent
WO2007070606A2 (en) * 2005-12-14 2007-06-21 E. I. Du Pont De Nemours And Company Isoxazolines for controlling invertebrate pests
WO2007074789A1 (ja) * 2005-12-26 2007-07-05 Nissan Chemical Industries, Ltd. １，３－ビス（置換フェニル）－３－ヒドロキシプロパン－１－オンおよび２－プロペン－１－オン化合物およびその塩

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3879532A (en) 1974-01-18 1975-04-22 Shell Oil Co Control by isoxazoles of endoparasitic nematodes
US4129568A (en) 1977-05-12 1978-12-12 Monsanto Company 2-[3-Aryl-2-isoxazolin-5-yl]benzoates
US5849736A (en) 1993-11-24 1998-12-15 The Dupont Merck Pharmaceutical Company Isoxazoline and isoxazole fibrinogen receptor antagonists
GB9505651D0 (en) 1995-03-21 1995-05-10 Agrevo Uk Ltd AgrEvo UK Limited
HUP9902423A3 (en) 1996-04-26 2001-02-28 Nippon Soda Co Benzene derivatives substituted by heterocycles and herbicides
AR007292A1 (es) 1996-06-06 1999-10-27 Rohm & Haas Compuestos aromaticos benciloxi sustituidos, una composicion fungicida, un metodo para controlar hongos fitopatogenicos y un metodo para controlarinsectos.
GB2351081A (en) 1999-06-18 2000-12-20 Lilly Forschung Gmbh Pharmaceutically active imidazoline compounds and analogues thereof
DE10114597A1 (de) 2001-03-23 2002-10-02 Bayer Cropscience Gmbh Arylisoxazolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
DE10320782A1 (de) 2003-05-09 2004-11-25 Bayer Cropscience Ag Substituierte Oxyarene
JP2005272452A (ja) 2004-02-23 2005-10-06 Nissan Chem Ind Ltd 置換ベンズアニリド化合物及び有害生物防除剤
WO2005094329A2 (en) 2004-03-26 2005-10-13 Cytokine Pharmasciences, Inc. Compouns, compositions, processes of making, and methods of use related to inhibiting macrophage migration inhibitory factor
JP5051340B2 (ja) * 2005-06-06 2012-10-17 日産化学工業株式会社 置換イソキサゾリン化合物及び有害生物防除剤
MY146795A (en) 2005-06-09 2012-09-28 Novartis Ag Process for the synthesis of organic compounds
GB0514071D0 (en) 2005-07-07 2005-08-17 Zealand Pharma As N- or C- terminally modified small peptides
KR100546831B1 (ko) 2005-08-31 2006-01-25 (주) 마이크로프랜드 프로브 카드의 탐침팁 공정 방법
CA2621228C (en) 2005-09-02 2014-05-27 Nissan Chemical Industries, Ltd. Isoxazoline-substituted benzamide compound and pesticide
JP2007106756A (ja) 2005-09-14 2007-04-26 Nissan Chem Ind Ltd 置換イソキサゾリン化合物及び有害生物防除剤
TWI266597B (en) * 2005-09-27 2006-11-11 Delta Electronics Inc Electronic apparatus capable of dissipating heat uniformly
TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
CN101400662B (zh) 2006-03-10 2012-11-14 日产化学工业株式会社 取代异噁唑啉化合物及有害生物防除剂
AU2007240954A1 (en) 2006-04-20 2007-11-01 E. I. Du Pont De Nemours And Company Pyrazolines for controlling invertebrate pests
JPWO2007125984A1 (ja) 2006-04-28 2009-09-10 日本農薬株式会社 イソキサゾリン誘導体及び有害生物防除剤並びにその使用方法
JP2008044880A (ja) 2006-08-15 2008-02-28 Bayer Cropscience Ag 殺虫性イソオキサゾリン類
US8119671B2 (en) 2007-03-07 2012-02-21 Nissan Chemical Industries, Ltd. Isoxazoline-substituted benzamide compound and pest control agent
AU2008235089B8 (en) * 2007-04-10 2014-04-10 Bayer Intellectual Property Gmbh Insecticidal aryl isoxazoline derivatives
JP5473906B2 (ja) 2007-06-13 2014-04-16 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー イソキサゾリン殺虫剤
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
EP2172462A4 (en) * 2007-06-27 2010-12-15 Nissan Chemical Ind Ltd METHOD FOR PRODUCING A 3-HYDROXYPROPAN-1-ON COMPOUND, METHOD FOR PRODUCING A 2-PROPENE-1-ON COMPOUND, AND METHOD FOR PRODUCING AN ISOXAZOLINE COMPOUND
CA2971008A1 (en) 2007-06-27 2008-12-31 E. I. Du Pont De Nemours And Company Animal pest control method
TWI461411B (zh) * 2007-08-17 2014-11-21 Du Pont 製備５－鹵烷基－４，５－二氫異唑衍生物之方法
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
US8318757B2 (en) 2007-09-10 2012-11-27 Nissan Chemical Industries, Ltd. Substituted isoxazoline compound and pest control agent
WO2009045999A1 (en) 2007-10-03 2009-04-09 E. I. Du Pont De Nemours And Company Naphthalene isoxazoline compounds for control of invertebrate pests

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050250822A1 (en) * 2002-08-26 2005-11-10 Takeshi Mita Substituted benzanilide compound and noxious organism controlling agent
WO2005085216A1 (ja) * 2004-03-05 2005-09-15 Nissan Chemical Industries, Ltd. イソキサゾリン置換ベンズアミド化合物及び有害生物防除剤
WO2007070606A2 (en) * 2005-12-14 2007-06-21 E. I. Du Pont De Nemours And Company Isoxazolines for controlling invertebrate pests
WO2007074789A1 (ja) * 2005-12-26 2007-07-05 Nissan Chemical Industries, Ltd. １，３－ビス（置換フェニル）－３－ヒドロキシプロパン－１－オンおよび２－プロペン－１－オン化合物およびその塩

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Ravindra R. Kamble., "An Efficient Synthesis of Pharmacologically Active Derivatives of 1,3,4-Oxadiazoles ", J. Heterocyclic Chem.,vol. 43, no.345, page345-352, 2006 *

Also Published As

Publication number Publication date
US20100249424A1 (en) 2010-09-30
MY150980A (en) 2014-03-31
IL203174A (en) 2014-08-31
US8513431B2 (en) 2013-08-20
JP5965102B2 (ja) 2016-08-03
MX2010001773A (es) 2010-03-10
KR20100044892A (ko) 2010-04-30
JP2010536767A (ja) 2010-12-02
CO6260136A2 (es) 2011-03-22
AU2008289321A1 (en) 2009-02-26
CN105693646A (zh) 2016-06-22
EP2176244A2 (en) 2010-04-21
ES2587386T3 (es) 2016-10-24
AU2008289321B2 (en) 2014-02-20
US8217180B2 (en) 2012-07-10
JP2014221775A (ja) 2014-11-27
RU2010109881A (ru) 2011-09-27
TW201718454A (zh) 2017-06-01
WO2009025983A3 (en) 2009-05-07
RU2536039C2 (ru) 2014-12-20
TW201434808A (zh) 2014-09-16
HK1143373A1 (zh) 2010-12-31
ZA201000214B (en) 2011-03-30
US20130165663A9 (en) 2013-06-27
AR067948A1 (es) 2009-10-28
EP2176244B1 (en) 2016-06-01
TW200914429A (en) 2009-04-01
BRPI0814153B1 (pt) 2018-08-21
BRPI0814153B8 (pt) 2022-12-06
CN101855215A (zh) 2010-10-06
CA2693067C (en) 2016-10-11
PT2176244T (pt) 2016-07-27
BRPI0814153A2 (pt) 2015-01-06
CA2693067A1 (en) 2009-02-26
US20120277442A1 (en) 2012-11-01
MY176115A (en) 2020-07-24
TWI649303B (zh) 2019-02-01
KR101597839B1 (ko) 2016-02-25
KR20150082693A (ko) 2015-07-15
WO2009025983A4 (en) 2009-06-25
TWI600639B (zh) 2017-10-01
WO2009025983A2 (en) 2009-02-26
MX337588B (es) 2016-03-11

Similar Documents

Publication Publication Date Title
TWI461411B (zh) 製備５－鹵烷基－４，５－二氫異唑衍生物之方法
TWI583664B (zh) 羰基化合物及其製備方法
HK1143373B (en) Method for preparing 5-haloalkyl-4,5-dihydroisoxazole derivatives
HK1154563B (en) Method for preparing 3-trifluoromethyl chalcones