TWI384988B - 處理中樞神經系統失常用之組成物 - Google Patents
處理中樞神經系統失常用之組成物 Download PDFInfo
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- TWI384988B TWI384988B TW095103028A TW95103028A TWI384988B TW I384988 B TWI384988 B TW I384988B TW 095103028 A TW095103028 A TW 095103028A TW 95103028 A TW95103028 A TW 95103028A TW I384988 B TWI384988 B TW I384988B
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- 239000007901 soft capsule Substances 0.000 description 1
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- LMYRWZFENFIFIT-UHFFFAOYSA-N toluene-4-sulfonamide Chemical compound CC1=CC=C(S(N)(=O)=O)C=C1 LMYRWZFENFIFIT-UHFFFAOYSA-N 0.000 description 1
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- 239000003440 toxic substance Substances 0.000 description 1
- 238000012549 training Methods 0.000 description 1
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
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- Veterinary Medicine (AREA)
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- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| US64700805P | 2005-01-27 | 2005-01-27 |
Publications (2)
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| TW200642690A TW200642690A (en) | 2006-12-16 |
| TWI384988B true TWI384988B (zh) | 2013-02-11 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW095103028A TWI384988B (zh) | 2005-01-27 | 2006-01-26 | 處理中樞神經系統失常用之組成物 |
Country Status (19)
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| US (2) | US8202909B2 (enExample) |
| EP (2) | EP2332545A1 (enExample) |
| JP (1) | JP5147404B2 (enExample) |
| KR (1) | KR101354771B1 (enExample) |
| CN (1) | CN101146541B (enExample) |
| AR (1) | AR055846A1 (enExample) |
| AU (1) | AU2006209072B2 (enExample) |
| BR (1) | BRPI0607084A2 (enExample) |
| CA (1) | CA2595898C (enExample) |
| DK (1) | DK1841433T3 (enExample) |
| ES (1) | ES2375082T3 (enExample) |
| IL (1) | IL184578A (enExample) |
| NO (1) | NO340257B1 (enExample) |
| NZ (1) | NZ556710A (enExample) |
| PL (1) | PL1841433T3 (enExample) |
| PT (1) | PT1841433E (enExample) |
| RU (1) | RU2440338C2 (enExample) |
| TW (1) | TWI384988B (enExample) |
| WO (1) | WO2006080549A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI225398B (en) * | 1999-07-14 | 2004-12-21 | R Tech Ueno Ltd | Composition for treatment of external secretion disorders |
| US20080207759A1 (en) * | 2007-02-27 | 2008-08-28 | Sucampo Ag | Method for protecting mitochondria |
| JP5390519B2 (ja) * | 2007-07-19 | 2014-01-15 | 株式会社アールテック・ウエノ | １１−デオキシ−プロスタグランジン化合物を含む医薬組成物およびその安定化方法 |
| US8871752B2 (en) * | 2008-02-19 | 2014-10-28 | Sucampo Ag | Method for modulating stem cell growth |
| US9084815B2 (en) | 2009-09-16 | 2015-07-21 | Sucampo Ag | Method for treating damage induced by an anti-tumor agent, treating mucositis and treating tumor |
| EP2627647B1 (en) * | 2010-10-15 | 2016-12-14 | Scinopharm (Kunshan) Biochemical Technology Co., Ltd. | Processes for preparation of lubiprostone |
| JP6023082B2 (ja) * | 2011-01-24 | 2016-11-09 | インセプタム リサーチ アンド セラピューティクス，インク． | 精神神経性の疾病を処置するためのプロスタグランジンを含む組成物 |
| BR112013026644A2 (pt) * | 2011-04-19 | 2016-12-27 | Sucampo Ag | método para a modulação da atividade de citocina |
| CN107903173A (zh) * | 2011-08-05 | 2018-04-13 | 苏坎波公司 | 治疗精神分裂症的方法 |
| WO2014159679A1 (en) | 2013-03-12 | 2014-10-02 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Methods for using lubiprostone to absorb fluid from the subretinal space |
| MX364197B (es) * | 2014-10-21 | 2019-04-16 | Univ Illes Balears | Proceso de sintesis de hidroxi-triacilgliceroles y usos de los mismos para la prevencion y el tratamiento de enfermedades. |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0690049A2 (en) * | 1994-06-03 | 1996-01-03 | R-Tech Ueno Ltd. | Agent for treating hepato biliary diseases |
| WO2000051978A1 (en) * | 1999-03-01 | 2000-09-08 | Nitromed, Inc. | Nitrosated and nitrosylated prostaglandins, compositions and metods of use |
| CN1522699A (zh) * | 2003-09-08 | 2004-08-25 | 秦正红 | 前列腺素a1在治疗脑缺血性中风等神经退行性疾病中的用途 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1120243A (en) | 1970-03-09 | 1968-07-17 | Samuelsson Bengt | Improvements in or relating to unsaturated carboxylic acid derivatives and the manufacture thereof |
| BE786215A (fr) | 1971-07-14 | 1973-01-15 | American Cyanamid Co | Nouveaux composes apparentes aux prostaglandines naturelles et procedesde leur preparation |
| ZA764727B (en) * | 1975-09-02 | 1977-07-27 | Upjohn Co | Prostanoic acid derivatives |
| SU845774A3 (ru) | 1976-04-20 | 1981-07-07 | Фармиталия Карло Эрба С.П.А. (Фирма) | Способ получени 13,14-дегидро-11-дЕзОКСипРОСТАглАНдиНОВ |
| US4131738A (en) * | 1977-07-05 | 1978-12-26 | The Upjohn Company | 6-Hydroxy-PGE1 compounds |
| CA1322749C (en) | 1987-01-28 | 1993-10-05 | Ryuzo Ueno | Prostaglandins of the d series, and tranquilizers and soporifics containing the same |
| US5166174A (en) | 1987-01-28 | 1992-11-24 | K.K. Ueno Seiyaku Oyo Kenkyujo | Prostaglandins E and anti-ulcers containing same |
| US5221763A (en) | 1987-04-30 | 1993-06-22 | R-Tech Ueno, Ltd. | Prostaglandins of the F series |
| US5317032A (en) * | 1987-10-02 | 1994-05-31 | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo | Prostaglandin cathartic |
| CA2030345C (en) | 1989-11-22 | 1998-12-08 | Ryuji Ueno | Use of 15-keto-prostaglandin compound for improvement of encephalic function |
| DE69106744T2 (de) | 1990-02-26 | 1995-05-18 | Ueno Seiyaku Oyo Kenkyujo Kk | 15-Dehydroxy-16-oxoprostaglandine. |
| TW249226B (enExample) | 1990-04-04 | 1995-06-11 | Aderk Ueno Kk | |
| JPH04187637A (ja) * | 1990-11-21 | 1992-07-06 | Ueno Seiyaku Oyo Kenkyusho:Kk | 記憶改善剤 |
| JPH07113012B2 (ja) | 1991-01-29 | 1995-12-06 | 株式会社アールテック・ウエノ | 新規１５−ケト−プロスタグランジン類 |
| JP3183615B2 (ja) * | 1994-06-03 | 2001-07-09 | 株式会社アールテック・ウエノ | 肝・胆道系疾患処置剤 |
| JP3187438B2 (ja) | 1996-06-10 | 2001-07-11 | 株式会社アールテック・ウエノ | エンドセリン拮抗剤 |
| CA2279267C (en) * | 1997-11-28 | 2010-01-12 | R-Tech Ueno, Ltd. | Use of 15-ketoprostaglandin e compounds as endothelin antagonist |
| JP3703004B2 (ja) | 1998-07-15 | 2005-10-05 | 小野薬品工業株式会社 | ５−チア−ω−置換フェニル−プロスタグランジンＥ誘導体 |
| TWI225398B (en) | 1999-07-14 | 2004-12-21 | R Tech Ueno Ltd | Composition for treatment of external secretion disorders |
| NZ521464A (en) * | 2000-03-24 | 2004-09-24 | Sucampo Ag | Apoptosis inhibiting composition comprising a 15-keto-prostaglandin or derivative thereof |
| US6414016B1 (en) * | 2000-09-05 | 2002-07-02 | Sucampo, A.G. | Anti-constipation composition |
| US20040224995A1 (en) * | 2003-05-09 | 2004-11-11 | University Of North Texas Health Science Center At Fort Worth | Neuroprotective effects of PPARy agonists against cellular oxidative insults |
-
2006
- 2006-01-26 BR BRPI0607084-1A patent/BRPI0607084A2/pt not_active Application Discontinuation
- 2006-01-26 PT PT06712847T patent/PT1841433E/pt unknown
- 2006-01-26 KR KR1020077019366A patent/KR101354771B1/ko not_active Expired - Fee Related
- 2006-01-26 US US11/339,495 patent/US8202909B2/en not_active Expired - Fee Related
- 2006-01-26 RU RU2007132081/04A patent/RU2440338C2/ru active
- 2006-01-26 WO PCT/JP2006/301704 patent/WO2006080549A2/en not_active Ceased
- 2006-01-26 TW TW095103028A patent/TWI384988B/zh not_active IP Right Cessation
- 2006-01-26 EP EP11155203A patent/EP2332545A1/en not_active Withdrawn
- 2006-01-26 ES ES06712847T patent/ES2375082T3/es active Active
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- 2006-01-26 CA CA2595898A patent/CA2595898C/en not_active Expired - Fee Related
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- 2006-01-26 CN CN2006800094248A patent/CN101146541B/zh not_active Expired - Fee Related
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- 2006-01-26 AR ARP060100290A patent/AR055846A1/es not_active Application Discontinuation
- 2006-01-26 JP JP2007535160A patent/JP5147404B2/ja not_active Expired - Fee Related
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2007
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2012
- 2012-05-14 US US13/470,377 patent/US20120225938A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0690049A2 (en) * | 1994-06-03 | 1996-01-03 | R-Tech Ueno Ltd. | Agent for treating hepato biliary diseases |
| WO2000051978A1 (en) * | 1999-03-01 | 2000-09-08 | Nitromed, Inc. | Nitrosated and nitrosylated prostaglandins, compositions and metods of use |
| CN1522699A (zh) * | 2003-09-08 | 2004-08-25 | 秦正红 | 前列腺素a1在治疗脑缺血性中风等神经退行性疾病中的用途 |
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| US20120225938A1 (en) | 2012-09-06 |
| AU2006209072B2 (en) | 2011-02-24 |
| IL184578A (en) | 2015-02-26 |
| AR055846A1 (es) | 2007-09-12 |
| PL1841433T3 (pl) | 2012-07-31 |
| NZ556710A (en) | 2010-08-27 |
| KR101354771B1 (ko) | 2014-01-22 |
| EP1841433B1 (en) | 2011-11-30 |
| US8202909B2 (en) | 2012-06-19 |
| CN101146541B (zh) | 2012-04-11 |
| CN101146541A (zh) | 2008-03-19 |
| US20060194880A1 (en) | 2006-08-31 |
| JP5147404B2 (ja) | 2013-02-20 |
| WO2006080549A2 (en) | 2006-08-03 |
| ES2375082T3 (es) | 2012-02-24 |
| TW200642690A (en) | 2006-12-16 |
| CA2595898A1 (en) | 2006-08-03 |
| DK1841433T3 (da) | 2012-01-16 |
| RU2440338C2 (ru) | 2012-01-20 |
| HK1118716A1 (en) | 2009-02-20 |
| BRPI0607084A2 (pt) | 2009-08-04 |
| AU2006209072A1 (en) | 2006-08-03 |
| RU2007132081A (ru) | 2009-03-10 |
| NO20074332L (no) | 2007-10-17 |
| CA2595898C (en) | 2015-04-28 |
| IL184578A0 (en) | 2007-10-31 |
| NO340257B1 (no) | 2017-03-27 |
| JP2008528440A (ja) | 2008-07-31 |
| KR20070107065A (ko) | 2007-11-06 |
| WO2006080549A3 (en) | 2007-07-05 |
| EP2332545A1 (en) | 2011-06-15 |
| PT1841433E (pt) | 2012-02-01 |
| EP1841433A2 (en) | 2007-10-10 |
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| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Annulment or lapse of patent due to non-payment of fees |