TWI240636B - Spontaneously dispersible pharmaceutical containing n-benzoyl-staurosporine and the use thereof - Google Patents
Spontaneously dispersible pharmaceutical containing n-benzoyl-staurosporine and the use thereof Download PDFInfo
- Publication number
- TWI240636B TWI240636B TW089104503A TW89104503A TWI240636B TW I240636 B TWI240636 B TW I240636B TW 089104503 A TW089104503 A TW 089104503A TW 89104503 A TW89104503 A TW 89104503A TW I240636 B TWI240636 B TW I240636B
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- Prior art keywords
- surfactant
- group
- composition
- polyoxyethylene
- cross
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- BMGQWWVMWDBQGC-IIFHNQTCSA-N midostaurin Chemical compound CN([C@H]1[C@H]([C@]2(C)O[C@@H](N3C4=CC=CC=C4C4=C5C(=O)NCC5=C5C6=CC=CC=C6N2C5=C43)C1)OC)C(=O)C1=CC=CC=C1 BMGQWWVMWDBQGC-IIFHNQTCSA-N 0.000 title abstract 3
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- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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Landscapes
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- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US6200968B1 (en) * | 1998-08-06 | 2001-03-13 | Cephalon, Inc. | Particle-forming compositions containing fused pyrrolocarbazoles |
| BR0208306A (pt) * | 2001-03-26 | 2004-03-09 | Novartis Ag | Composições farmacêuticas |
| PL392652A1 (pl) | 2001-05-16 | 2010-12-06 | Novartis Ag | Kombinacja zawierająca N-{5-[4-(4-metylo-piperazyno-metylo)-benzoiloamido]-2-metylofenylo}-4-(3-pirydylo)-2-pirymidyno-aminę oraz środek chemoterapeutyczny, jej zastosowanie, kompozycja farmaceutyczna ją zawierająca oraz zestaw zawierający taką kombinację |
| EP1441737B1 (en) | 2001-10-30 | 2006-08-09 | Novartis AG | Staurosporine derivatives as inhibitors of flt3 receptor tyrosine kinase activity |
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| FR2918566B1 (fr) | 2007-07-11 | 2009-10-09 | Pierre Fabre Medicament Sa | Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine. |
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| GB9325395D0 (en) * | 1993-12-11 | 1994-02-16 | Ciba Geigy Ag | Compositions |
| AU1911095A (en) * | 1994-02-18 | 1995-09-04 | Cephalon, Inc. | Aqueous indolocarbazole solutions |
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1999
- 1999-02-16 GB GBGB9903547.9A patent/GB9903547D0/en not_active Ceased
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2000
- 2000-02-14 EP EP00909165A patent/EP1152750B1/en not_active Expired - Lifetime
- 2000-02-14 AU AU31542/00A patent/AU765776B2/en not_active Expired
- 2000-02-14 DK DK00909165T patent/DK1152750T3/da active
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- 2000-02-14 PE PE2000000113A patent/PE20001499A1/es not_active Application Discontinuation
- 2000-02-14 TR TR2001/02385T patent/TR200102385T2/xx unknown
- 2000-02-14 CZ CZ20012931A patent/CZ303979B6/cs not_active IP Right Cessation
- 2000-02-14 AT AT00909165T patent/ATE430554T1/de active
- 2000-02-14 CN CNB008038244A patent/CN100367930C/zh not_active Expired - Lifetime
- 2000-02-14 HK HK02106758.7A patent/HK1045807B/zh not_active IP Right Cessation
- 2000-02-14 BR BRPI0008228A patent/BRPI0008228B8/pt not_active IP Right Cessation
- 2000-02-14 HU HU0105364A patent/HUP0105364A3/hu unknown
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- 2000-02-14 KR KR1020087015449A patent/KR20080064914A/ko not_active Withdrawn
- 2000-02-14 PT PT00909165T patent/PT1152750E/pt unknown
- 2000-02-14 RU RU2001124597/15A patent/RU2266121C2/ru active
- 2000-02-14 SI SI200031035T patent/SI1152750T1/sl unknown
- 2000-02-14 KR KR1020017009391A patent/KR100880859B1/ko not_active Expired - Lifetime
- 2000-02-14 DE DE60042151T patent/DE60042151D1/de not_active Expired - Lifetime
- 2000-02-14 PL PL350556A patent/PL198330B1/pl unknown
- 2000-02-14 SK SK1172-2001A patent/SK286967B6/sk not_active IP Right Cessation
- 2000-02-14 NZ NZ513529A patent/NZ513529A/en not_active IP Right Cessation
- 2000-02-14 ES ES00909165T patent/ES2326783T3/es not_active Expired - Lifetime
- 2000-02-14 JP JP2000599363A patent/JP5057610B2/ja not_active Expired - Fee Related
- 2000-02-14 WO PCT/EP2000/001196 patent/WO2000048571A1/en not_active Ceased
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2001
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- 2001-07-23 IL IL144512A patent/IL144512A/en not_active IP Right Cessation
- 2001-08-15 US US09/930,335 patent/US20020061873A1/en not_active Abandoned
- 2001-08-15 NO NO20013964A patent/NO331232B1/no not_active IP Right Cessation
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2007
- 2007-09-21 US US11/859,077 patent/US8575147B2/en not_active Expired - Fee Related
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2008
- 2008-07-04 EC EC2008003351A patent/ECSP083351A/es unknown
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2009
- 2009-07-31 CL CL2009001682A patent/CL2009001682A1/es unknown
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2011
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2012
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2013
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