AU2565895A - Indolocarbazole derivatives for sensitizing multidrug-resistant cells to antitumor agents - Google Patents
Indolocarbazole derivatives for sensitizing multidrug-resistant cells to antitumor agentsInfo
- Publication number
- AU2565895A AU2565895A AU25658/95A AU2565895A AU2565895A AU 2565895 A AU2565895 A AU 2565895A AU 25658/95 A AU25658/95 A AU 25658/95A AU 2565895 A AU2565895 A AU 2565895A AU 2565895 A AU2565895 A AU 2565895A
- Authority
- AU
- Australia
- Prior art keywords
- antitumor agents
- resistant cells
- indolocarbazole derivatives
- sensitizing multidrug
- multidrug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/044—Pyrrole radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/06—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing nitrogen as ring hetero atoms
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1714/94 | 1994-06-01 | ||
CH171494 | 1994-06-01 | ||
PCT/EP1995/001910 WO1995032975A1 (en) | 1994-06-01 | 1995-05-19 | Indolocarbazole derivatives for sensitizing multidrug-resistant cells to antitumor agents |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2565895A true AU2565895A (en) | 1995-12-21 |
Family
ID=4216887
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU25658/95A Abandoned AU2565895A (en) | 1994-06-01 | 1995-05-19 | Indolocarbazole derivatives for sensitizing multidrug-resistant cells to antitumor agents |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0763041A1 (en) |
JP (1) | JPH10501527A (en) |
AU (1) | AU2565895A (en) |
WO (1) | WO1995032975A1 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6232299B1 (en) * | 1996-05-01 | 2001-05-15 | Eli Lilly And Company | Use of protein kinase C inhibitors to enhance the clinical efficacy of oncolytic agents and radiation therapy |
CA2245029A1 (en) | 1998-03-13 | 1999-09-13 | University Of British Columbia | Granulatimide compounds as g2 checkpoint inhibitors |
ATE251624T1 (en) * | 1998-03-13 | 2003-10-15 | Univ British Columbia | GRANULATIMIDE DERIVATIVES FOR THE TREATMENT OF CANCER |
US6127401A (en) * | 1998-06-05 | 2000-10-03 | Cephalon, Inc. | Bridged indenopyrrolocarbazoles |
GB9903547D0 (en) | 1999-02-16 | 1999-04-07 | Novartis Ag | Organic compounds |
CA2379035A1 (en) | 1999-07-13 | 2001-01-18 | Shiro Akinaga | Staurosporin derivatives |
US6693099B2 (en) | 2000-10-17 | 2004-02-17 | The Procter & Gamble Company | Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance |
JO2897B1 (en) * | 2004-11-05 | 2015-09-15 | نوفارتيس ايه جي | Organic compounds |
JP2009504608A (en) * | 2005-08-09 | 2009-02-05 | ヨハネス・グーテンベルク−ウニヴェルジテート・マインツ | Sensitization of drug-resistant lung cancer to protein kinase inhibitors |
ES2611486T3 (en) | 2014-05-30 | 2017-05-09 | Entrechem, S.L. | Antitumor activity of multiple kinase inhibitors in triple negative breast cancer |
CN108299467B (en) * | 2018-02-27 | 2020-04-28 | 中国海洋大学 | Indolocarbazole alkaloid with cytotoxic activity, preparation method and application thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1989007105A1 (en) * | 1988-02-04 | 1989-08-10 | Kyowa Hakko Kogyo Co., Ltd. | Staurosporin derivatives |
JPH03220194A (en) * | 1989-11-30 | 1991-09-27 | Asahi Chem Ind Co Ltd | Staurosporine carboxylic acid derivative |
JPH04145085A (en) * | 1990-09-25 | 1992-05-19 | Asahi Chem Ind Co Ltd | Gamma-lactam ring derivative of staurosporin and ammonium salt thereof |
US5674867A (en) * | 1992-09-21 | 1997-10-07 | Kyowa Hakko Kogyo Co., Ltd. | Indolocarbazole derivatives and therapeutic method for stimulating megakaicyocyte production |
EP0643966A4 (en) * | 1993-03-03 | 1995-08-09 | Kyowa Hakko Kogyo Kk | Sensitivity enhancer for antineoplastic agent. |
JPH08511785A (en) * | 1993-06-17 | 1996-12-10 | チバ−ガイギー アクチェンゲゼルシャフト | Indolocarbazole useful as a protein kinase C inhibitor |
-
1995
- 1995-05-19 WO PCT/EP1995/001910 patent/WO1995032975A1/en not_active Application Discontinuation
- 1995-05-19 EP EP95920067A patent/EP0763041A1/en not_active Withdrawn
- 1995-05-19 JP JP8500245A patent/JPH10501527A/en active Pending
- 1995-05-19 AU AU25658/95A patent/AU2565895A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0763041A1 (en) | 1997-03-19 |
WO1995032975A1 (en) | 1995-12-07 |
JPH10501527A (en) | 1998-02-10 |
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