AU2565995A - Polycyclic lactam derivatives for sensitizing multidrug-resistant cells to antitumour agents - Google Patents
Polycyclic lactam derivatives for sensitizing multidrug-resistant cells to antitumour agentsInfo
- Publication number
- AU2565995A AU2565995A AU25659/95A AU2565995A AU2565995A AU 2565995 A AU2565995 A AU 2565995A AU 25659/95 A AU25659/95 A AU 25659/95A AU 2565995 A AU2565995 A AU 2565995A AU 2565995 A AU2565995 A AU 2565995A
- Authority
- AU
- Australia
- Prior art keywords
- resistant cells
- lactam derivatives
- antitumour agents
- sensitizing multidrug
- polycyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/044—Pyrrole radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/06—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing nitrogen as ring hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1715/94 | 1994-06-01 | ||
CH171594 | 1994-06-01 | ||
PCT/EP1995/001911 WO1995032976A1 (en) | 1994-06-01 | 1995-05-19 | Polycyclic lactam derivatives for sensitizing multidrug-resistant cells to antitumour agents |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2565995A true AU2565995A (en) | 1995-12-21 |
Family
ID=4216912
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU25659/95A Abandoned AU2565995A (en) | 1994-06-01 | 1995-05-19 | Polycyclic lactam derivatives for sensitizing multidrug-resistant cells to antitumour agents |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0763042A1 (en) |
JP (1) | JPH10500394A (en) |
AU (1) | AU2565995A (en) |
WO (1) | WO1995032976A1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CO4940430A1 (en) * | 1997-07-07 | 2000-07-24 | Novartis Ag | POLYCLIC COMPOUNDS CONTAINING HYDROGENATED STAUROSPORIN WITH CONVENIENT PHARMACOLOGICAL PROPERTIES AND AN INHIBITING EFFECT ON THE GROWTH OF TUMOR CELLS |
CA2245029A1 (en) | 1998-03-13 | 1999-09-13 | University Of British Columbia | Granulatimide compounds as g2 checkpoint inhibitors |
EP1070068B2 (en) * | 1998-03-13 | 2007-01-17 | The University Of British Columbia | Granulatimide derivatives for use in cancer treatment |
CA2379035A1 (en) | 1999-07-13 | 2001-01-18 | Shiro Akinaga | Staurosporin derivatives |
US6693099B2 (en) | 2000-10-17 | 2004-02-17 | The Procter & Gamble Company | Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance |
CN1582150B (en) | 2001-10-30 | 2011-09-07 | 诺瓦提斯公司 | Staurosporine derivatives as inhibitors of FLT3 receptor tyrosine kinase activity |
CA2533861A1 (en) | 2003-08-08 | 2005-02-17 | Novartis Ag | Combinations comprising staurosporines |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2766360B2 (en) * | 1988-02-04 | 1998-06-18 | 協和醗酵工業株式会社 | Staurosporine derivative |
US5674867A (en) * | 1992-09-21 | 1997-10-07 | Kyowa Hakko Kogyo Co., Ltd. | Indolocarbazole derivatives and therapeutic method for stimulating megakaicyocyte production |
EP0643966A4 (en) * | 1993-03-03 | 1995-08-09 | Kyowa Hakko Kogyo Kk | Sensitivity enhancer for antineoplastic agent. |
WO1995000520A1 (en) * | 1993-06-17 | 1995-01-05 | Ciba-Geigy Ag | Indolocarbazole compound useful as proteinkinase c inhibitor |
-
1995
- 1995-05-19 EP EP95920068A patent/EP0763042A1/en not_active Withdrawn
- 1995-05-19 JP JP7524229A patent/JPH10500394A/en active Pending
- 1995-05-19 WO PCT/EP1995/001911 patent/WO1995032976A1/en not_active Application Discontinuation
- 1995-05-19 AU AU25659/95A patent/AU2565995A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1995032976A1 (en) | 1995-12-07 |
JPH10500394A (en) | 1998-01-13 |
EP0763042A1 (en) | 1997-03-19 |
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