TWI227274B - Enhanced immunogen for inactivated vaccine for infection with Japanese encephalitis viruses and process for producing the same - Google Patents
Enhanced immunogen for inactivated vaccine for infection with Japanese encephalitis viruses and process for producing the same Download PDFInfo
- Publication number
- TWI227274B TWI227274B TW88109144A TW88109144A TWI227274B TW I227274 B TWI227274 B TW I227274B TW 88109144 A TW88109144 A TW 88109144A TW 88109144 A TW88109144 A TW 88109144A TW I227274 B TWI227274 B TW I227274B
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- Taiwan
- Prior art keywords
- virus
- deactivated
- japanese encephalitis
- vaccine
- particle
- Prior art date
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
- C12N7/06—Inactivation or attenuation by chemical treatment
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24151—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24161—Methods of inactivation or attenuation
- C12N2770/24163—Methods of inactivation or attenuation by chemical treatment
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP31976298 | 1998-10-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TWI227274B true TWI227274B (en) | 2005-02-01 |
Family
ID=18113906
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW88109144A TWI227274B (en) | 1998-10-05 | 1999-06-02 | Enhanced immunogen for inactivated vaccine for infection with Japanese encephalitis viruses and process for producing the same |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6841374B1 (enExample) |
| EP (1) | EP1057889B1 (enExample) |
| JP (2) | JP4371343B2 (enExample) |
| KR (1) | KR20010032699A (enExample) |
| CN (2) | CN1618464A (enExample) |
| AU (1) | AU743546B2 (enExample) |
| CA (1) | CA2311336C (enExample) |
| MY (1) | MY126520A (enExample) |
| TW (1) | TWI227274B (enExample) |
| WO (1) | WO2000020565A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10144906B4 (de) * | 2001-09-12 | 2013-11-28 | Novartis Vaccines And Diagnostics Gmbh | Verfahren zur großtechnischen Herstellung von Impfstoffen |
| US7060280B2 (en) * | 2003-06-11 | 2006-06-13 | Academia Sinica | Immunization against flavivirus |
| US7780027B2 (en) * | 2007-02-08 | 2010-08-24 | Michael Coady | Axially stacked double barrel animal feeder system |
| JP5535910B2 (ja) * | 2007-08-28 | 2014-07-02 | バクスター・インターナショナル・インコーポレイテッド | ウイルスワクチンを生産する方法 |
| WO2009082002A1 (ja) | 2007-12-26 | 2009-07-02 | The Kitasato Institute | 安定に長期間保存できる日本脳炎ワクチンの製法方法及び該ワクチンの用途 |
| JP5511660B2 (ja) | 2008-06-04 | 2014-06-04 | 一般財団法人化学及血清療法研究所 | 不活化日本脳炎ウイルス粒子をアジュバントとして使用する方法 |
| CN101333246B (zh) * | 2008-07-30 | 2011-04-13 | 中国农业科学院哈尔滨兽医研究所 | 乙型脑炎病毒e蛋白中和性b细胞抗原表位多肽及其应用 |
| CA3001374A1 (en) * | 2008-11-17 | 2010-05-20 | Vgx Pharmaceuticals, Llc | Antigens that elicit immune response against flavivirus and methods of using same |
| KR20120027381A (ko) * | 2009-05-25 | 2012-03-21 | 파나세아 바이오테크 리미티드 | 일본뇌염 백신 및 그것의 제조 방법 |
| CN101792741A (zh) * | 2010-04-07 | 2010-08-04 | 西北农林科技大学 | 表达jev免疫原基因的重组杆状病毒及其制备和应用 |
| JP6963460B2 (ja) * | 2016-10-27 | 2021-11-10 | 一般財団法人阪大微生物病研究会 | たん白質の定量方法 |
| WO2021161390A1 (ja) * | 2020-02-10 | 2021-08-19 | 花王株式会社 | ヒトノロウイルス不活化評価法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6147185A (ja) * | 1984-08-09 | 1986-03-07 | Chemo Sero Therapeut Res Inst | 日本脳炎ウイルスの精製方法 |
| JPS6153227A (ja) * | 1984-08-23 | 1986-03-17 | Biseibutsu Kagaku Kenkyusho:Kk | 日本脳炎・豚パルボウイルス感染症混合生ワクチン |
| AT393356B (de) * | 1989-12-22 | 1991-10-10 | Immuno Ag | Verfahren zur herstellung von fsme-virus-antigen |
| US5719051A (en) * | 1989-12-22 | 1998-02-17 | Immuno Aktiengesellschaft | Perfusion system and a method for the large scale production of virus or virus antigen |
| JPH07265093A (ja) * | 1994-03-30 | 1995-10-17 | Chemo Sero Therapeut Res Inst | 哺乳動物細胞を用いる日本脳炎ウイルス表面抗原蛋白質の製法 |
| WO1997004803A1 (fr) | 1995-08-01 | 1997-02-13 | Pasteur Merieux Serums & Vaccins | Procede de production industrielle d'un vaccin contre l'encephalite japonaise et vaccin obtenu |
| US6207439B1 (en) * | 1997-03-25 | 2001-03-27 | Center For Disease Control | Purification of Japanese encephalitis virus |
| US5891705A (en) | 1997-04-08 | 1999-04-06 | Pentose Pharmaceuticals, Inc. | Method for inactivating a virus |
| DE122009000037I2 (de) | 1997-08-28 | 2011-06-16 | Cheil Jedang Corp | Ein an vero-zellen angepasstes abgeschwächtes japanisches enzephalitis virus und ein impfstoff gegen japanische enzephalitis |
-
1999
- 1999-06-02 WO PCT/JP1999/002931 patent/WO2000020565A1/ja not_active Ceased
- 1999-06-02 CN CNA2004100473162A patent/CN1618464A/zh active Pending
- 1999-06-02 KR KR1020007005984A patent/KR20010032699A/ko not_active Ceased
- 1999-06-02 CA CA 2311336 patent/CA2311336C/en not_active Expired - Fee Related
- 1999-06-02 AU AU40578/99A patent/AU743546B2/en not_active Ceased
- 1999-06-02 JP JP2000574663A patent/JP4371343B2/ja not_active Expired - Lifetime
- 1999-06-02 EP EP99923858A patent/EP1057889B1/en not_active Expired - Lifetime
- 1999-06-02 US US09/555,704 patent/US6841374B1/en not_active Expired - Fee Related
- 1999-06-02 CN CNB998017647A patent/CN1160454C/zh not_active Expired - Fee Related
- 1999-06-02 TW TW88109144A patent/TWI227274B/zh not_active IP Right Cessation
- 1999-06-03 MY MYPI99002242A patent/MY126520A/en unknown
-
2009
- 2009-07-08 JP JP2009162261A patent/JP5095685B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1057889A1 (en) | 2000-12-06 |
| JP2009225809A (ja) | 2009-10-08 |
| CN1287573A (zh) | 2001-03-14 |
| MY126520A (en) | 2006-10-31 |
| CA2311336C (en) | 2007-01-02 |
| US6841374B1 (en) | 2005-01-11 |
| EP1057889B1 (en) | 2009-04-22 |
| WO2000020565A1 (en) | 2000-04-13 |
| CN1618464A (zh) | 2005-05-25 |
| CN1160454C (zh) | 2004-08-04 |
| JP5095685B2 (ja) | 2012-12-12 |
| AU743546B2 (en) | 2002-01-31 |
| CA2311336A1 (en) | 2000-04-13 |
| KR20010032699A (ko) | 2001-04-25 |
| AU4057899A (en) | 2000-04-26 |
| JP4371343B2 (ja) | 2009-11-25 |
| EP1057889A4 (en) | 2002-01-23 |
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