TW268005B - - Google Patents
Info
- Publication number
- TW268005B TW268005B TW082104161A TW82104161A TW268005B TW 268005 B TW268005 B TW 268005B TW 082104161 A TW082104161 A TW 082104161A TW 82104161 A TW82104161 A TW 82104161A TW 268005 B TW268005 B TW 268005B
- Authority
- TW
- Taiwan
- Prior art keywords
- alkyl
- optionally substituted
- cycloalkyl
- alkyl groups
- halo
- Prior art date
Links
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- 125000006374 C2-C10 alkenyl group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Anesthesiology (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929211379A GB9211379D0 (en) | 1992-05-29 | 1992-05-29 | Pharmaceutical compounds |
| GB939309025A GB9309025D0 (en) | 1993-04-30 | 1993-04-30 | Pharmaceutical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW268005B true TW268005B (enExample) | 1996-01-11 |
Family
ID=26300951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW082104161A TW268005B (enExample) | 1992-05-29 | 1993-05-26 |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0582368B1 (enExample) |
| JP (1) | JP3219541B2 (enExample) |
| CN (1) | CN1043994C (enExample) |
| AT (1) | ATE198891T1 (enExample) |
| AU (1) | AU668159B2 (enExample) |
| CA (1) | CA2097016A1 (enExample) |
| CZ (1) | CZ282783B6 (enExample) |
| DE (1) | DE69329887T2 (enExample) |
| DK (1) | DK0582368T3 (enExample) |
| ES (1) | ES2153373T3 (enExample) |
| FI (1) | FI101538B (enExample) |
| GR (1) | GR3035587T3 (enExample) |
| HU (1) | HU218278B (enExample) |
| IL (1) | IL105827A (enExample) |
| MX (1) | MX9303124A (enExample) |
| MY (1) | MY109943A (enExample) |
| NO (1) | NO305125B1 (enExample) |
| NZ (1) | NZ247703A (enExample) |
| PT (1) | PT582368E (enExample) |
| RU (1) | RU2125574C1 (enExample) |
| TW (1) | TW268005B (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5457101A (en) * | 1994-06-03 | 1995-10-10 | Eli Lilly And Company | Thieno[1,5]benzoidiazepine use |
| US5574028A (en) * | 1994-10-31 | 1996-11-12 | Eli Lilly And Company | Method for treating anxiety |
| CR5278A (es) | 1995-03-24 | 1996-07-04 | Lilly Co Eli | Formulacion oral de 2-metil-tieno-benzodiacepina |
| EG23659A (en) * | 1995-03-24 | 2007-03-26 | Lilly Co Eli | Process and crystal forms of methyl-thieno-benzodiazepine |
| EG24221A (en) * | 1995-03-24 | 2008-11-10 | Lilly Co Eli | Process for preparing olanzapine |
| US5891461A (en) * | 1995-09-14 | 1999-04-06 | Cygnus, Inc. | Transdermal administration of olanzapine |
| PL329221A1 (en) * | 1996-03-25 | 1999-03-15 | Lilly Co Eli | Method of relieving hemicrania pains |
| NZ332039A (en) * | 1996-03-25 | 2000-06-23 | Lilly Co Eli | Method for treating pain using olanzapine and NSAIDs |
| CZ298198A3 (cs) * | 1996-03-25 | 1999-06-16 | Eli Lilly And Company | Farmaceutický přípravek |
| ZA978515B (en) * | 1996-09-23 | 1999-03-23 | Lilly Co Eli | Intermediates and process for preparing olanzapine |
| TR199900639T2 (xx) | 1996-09-23 | 1999-06-21 | Eli Lilly And Company | Olanzapin dihidrat D. |
| CN1230883A (zh) * | 1996-09-24 | 1999-10-06 | 伊莱利利公司 | 包衣颗粒制剂 |
| RU2185383C1 (ru) * | 2001-05-22 | 2002-07-20 | Институт молекулярной генетики РАН | ВЫСОКОМЕЧЕННЫЙ ТРИТИЕМ 2-МЕТИЛ-4-(4-МЕТИЛ-1-ПИПЕРАЗИНИЛ)-10Н-ТИЕНО[2,3-b][1,5]БЕНЗОДИАЗЕПИН |
| CN104736566A (zh) | 2012-08-21 | 2015-06-24 | 奥索临床诊断有限公司 | 帕潘立酮半抗原的抗体及其用途 |
| CN104822660A (zh) | 2012-08-21 | 2015-08-05 | 詹森药业有限公司 | 阿立哌唑半抗原及其在免疫测定中的应用 |
| CN104755928B (zh) | 2012-08-21 | 2017-05-10 | 詹森药业有限公司 | 奥氮平的抗体及其用途 |
| ES2666000T3 (es) | 2012-08-21 | 2018-04-30 | Janssen Pharmaceutica, N.V. | Anticuerpos para aripiprazol y uso de los mismos |
| ES2822004T3 (es) | 2012-08-21 | 2021-04-28 | Janssen Pharmaceutica Nv | Anticuerpos contra quetiapina y uso de los mismos |
| ES2926662T3 (es) | 2012-08-21 | 2022-10-27 | Janssen Pharmaceutica Nv | Anticuerpos contra haptenos de risperidona y uso de los mismos |
| AU2013305965B2 (en) | 2012-08-21 | 2017-08-24 | Saladax Biomedical Inc. | Antibodies to paliperidone and use thereof |
| AU2013306018B2 (en) * | 2012-08-21 | 2017-08-10 | Saladax Biomedical Inc. | Haptens of olanzapine |
| PT3663317T (pt) | 2012-08-21 | 2023-01-23 | Janssen Pharmaceutica Nv | Anticorpos para haptenos de quetiapina e sua utilização |
| PL2888258T3 (pl) | 2012-08-21 | 2019-10-31 | Janssen Pharmaceutica Nv | Hapteny paliperydonu |
| EP2888263B1 (en) | 2012-08-21 | 2018-05-09 | Janssen Pharmaceutica NV | Haptens of risperidone and paliperidone |
| EP3305784B1 (en) | 2012-08-21 | 2020-08-12 | Janssen Pharmaceutica NV | Haptens of quetiapine for use in immunoassays |
| ES2691092T3 (es) | 2012-08-21 | 2018-11-23 | Janssen Pharmaceutica Nv | Anticuerpos contra la risperidona y uso de los mismos |
| EP3581195B1 (en) | 2012-08-21 | 2025-10-01 | Janssen Pharmaceutica NV | Antibodies to olanzapine haptens and use thereof |
| US9611332B2 (en) | 2012-08-21 | 2017-04-04 | Janssen Pharmaceutica Nv | Antibodies to aripiprazole haptens and use thereof |
| WO2017106501A1 (en) | 2015-12-17 | 2017-06-22 | Janssen Pharmaceutica Nv | Antibodies to risperidone and use thereof |
| EP3390455A1 (en) | 2015-12-17 | 2018-10-24 | Janssen Pharmaceutica NV | Antibodies to quetiapine and use thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH569730A5 (enExample) * | 1972-04-04 | 1975-11-28 | Wander Ag Dr A | |
| US3962248A (en) * | 1972-04-04 | 1976-06-08 | Sandoz, Inc. | Process for making 11-piperazino-diazepines, oxazepines, thiazepines and azepines |
| SU629879A3 (ru) * | 1974-11-26 | 1978-10-25 | Лилли Индастриз Лимитед, (Фирма) | Способ получени тиено(1,5) бензодиазепинов или их солей |
| US4061752A (en) * | 1975-08-06 | 1977-12-06 | Sandoz Ltd. | 6-Piperazino-11-methylene-dibenzazepines[b,e] |
| FI762646A7 (enExample) * | 1975-09-24 | 1977-03-25 | Sandoz Ag | |
| CH624682A5 (enExample) * | 1976-11-10 | 1981-08-14 | Sandoz Ag | |
| US4761411A (en) * | 1983-05-18 | 1988-08-02 | Hoechst-Roussel Pharmaceuticals Inc. | Dihydrobenzopyrrolobenzodiazepines useful for treating pyschoses |
| GB9009229D0 (en) * | 1990-04-25 | 1990-06-20 | Lilly Industries Ltd | Pharmaceutical compounds |
-
1993
- 1993-05-26 CA CA002097016A patent/CA2097016A1/en not_active Abandoned
- 1993-05-26 NZ NZ247703A patent/NZ247703A/en unknown
- 1993-05-26 EP EP93304102A patent/EP0582368B1/en not_active Expired - Lifetime
- 1993-05-26 AT AT93304102T patent/ATE198891T1/de not_active IP Right Cessation
- 1993-05-26 PT PT93304102T patent/PT582368E/pt unknown
- 1993-05-26 AU AU39807/93A patent/AU668159B2/en not_active Ceased
- 1993-05-26 NO NO931917A patent/NO305125B1/no not_active IP Right Cessation
- 1993-05-26 TW TW082104161A patent/TW268005B/zh active
- 1993-05-26 DK DK93304102T patent/DK0582368T3/da active
- 1993-05-26 DE DE69329887T patent/DE69329887T2/de not_active Expired - Fee Related
- 1993-05-26 ES ES93304102T patent/ES2153373T3/es not_active Expired - Lifetime
- 1993-05-27 MX MX9303124A patent/MX9303124A/es not_active IP Right Cessation
- 1993-05-28 HU HU9301579A patent/HU218278B/hu not_active IP Right Cessation
- 1993-05-28 RU RU93005057A patent/RU2125574C1/ru active
- 1993-05-28 IL IL10582793A patent/IL105827A/xx not_active IP Right Cessation
- 1993-05-28 JP JP12642993A patent/JP3219541B2/ja not_active Expired - Fee Related
- 1993-05-28 CN CN93108212A patent/CN1043994C/zh not_active Expired - Fee Related
- 1993-05-28 CZ CZ931024A patent/CZ282783B6/cs not_active IP Right Cessation
- 1993-05-28 MY MYPI93001036A patent/MY109943A/en unknown
- 1993-05-28 FI FI932445A patent/FI101538B/fi active
-
2001
- 2001-03-15 GR GR20010400431T patent/GR3035587T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| MY109943A (en) | 1997-10-31 |
| PT582368E (pt) | 2001-05-31 |
| IL105827A (en) | 1997-02-18 |
| CZ102493A3 (en) | 1993-12-15 |
| CN1085903A (zh) | 1994-04-27 |
| GR3035587T3 (en) | 2001-06-29 |
| ES2153373T3 (es) | 2001-03-01 |
| DK0582368T3 (da) | 2001-02-05 |
| CZ282783B6 (cs) | 1997-10-15 |
| FI932445L (fi) | 1993-11-30 |
| JP3219541B2 (ja) | 2001-10-15 |
| NZ247703A (en) | 1995-07-26 |
| ATE198891T1 (de) | 2001-02-15 |
| EP0582368B1 (en) | 2001-01-24 |
| JPH0687862A (ja) | 1994-03-29 |
| AU3980793A (en) | 1993-12-02 |
| HUT66180A (en) | 1994-09-28 |
| AU668159B2 (en) | 1996-04-26 |
| HU218278B (en) | 2000-07-28 |
| EP0582368A1 (en) | 1994-02-09 |
| MX9303124A (es) | 1993-11-01 |
| NO305125B1 (no) | 1999-04-06 |
| FI101538B1 (fi) | 1998-07-15 |
| IL105827A0 (en) | 1993-09-22 |
| HU9301579D0 (en) | 1993-09-28 |
| CN1043994C (zh) | 1999-07-07 |
| DE69329887D1 (de) | 2001-03-01 |
| FI101538B (fi) | 1998-07-15 |
| NO931917D0 (no) | 1993-05-26 |
| CA2097016A1 (en) | 1993-11-30 |
| NO931917L (no) | 1993-11-30 |
| RU2125574C1 (ru) | 1999-01-27 |
| FI932445A0 (fi) | 1993-05-28 |
| DE69329887T2 (de) | 2001-05-23 |
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