TW202405183A - 經修飾以增加麥角硫醇生產力之核酸及經基因修飾之微生物 - Google Patents

經修飾以增加麥角硫醇生產力之核酸及經基因修飾之微生物 Download PDF

Info

Publication number
TW202405183A
TW202405183A TW112120151A TW112120151A TW202405183A TW 202405183 A TW202405183 A TW 202405183A TW 112120151 A TW112120151 A TW 112120151A TW 112120151 A TW112120151 A TW 112120151A TW 202405183 A TW202405183 A TW 202405183A
Authority
TW
Taiwan
Prior art keywords
sequence
nucleic acid
region
amino acid
functional domain
Prior art date
Application number
TW112120151A
Other languages
English (en)
Chinese (zh)
Inventor
田嶋遼子
市川惠一
伊藤考太郎
Original Assignee
日商龜甲萬股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 日商龜甲萬股份有限公司 filed Critical 日商龜甲萬股份有限公司
Publication of TW202405183A publication Critical patent/TW202405183A/zh

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/38Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
TW112120151A 2022-05-31 2023-05-30 經修飾以增加麥角硫醇生產力之核酸及經基因修飾之微生物 TW202405183A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2022-089120 2022-05-31
JP2022089120 2022-05-31
JP2022112588 2022-07-13
JP2022-112588 2022-07-13

Publications (1)

Publication Number Publication Date
TW202405183A true TW202405183A (zh) 2024-02-01

Family

ID=89024879

Family Applications (1)

Application Number Title Priority Date Filing Date
TW112120151A TW202405183A (zh) 2022-05-31 2023-05-30 經修飾以增加麥角硫醇生產力之核酸及經基因修飾之微生物

Country Status (6)

Country Link
EP (1) EP4534673A1 (https=)
JP (1) JPWO2023234307A1 (https=)
KR (1) KR20250007610A (https=)
CN (1) CN119343451A (https=)
TW (1) TW202405183A (https=)
WO (1) WO2023234307A1 (https=)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2707087B1 (fr) 1993-06-28 1995-10-13 Bioxytech Nouveau procédé de préparation de l'ergothionéine.
WO2016104437A1 (ja) 2014-12-22 2016-06-30 国立大学法人 岡山大学 エルゴチオネインの産生方法
WO2016121285A1 (ja) * 2015-01-30 2016-08-04 キッコーマン株式会社 エルゴチオネイン生産能が増強された形質転換糸状菌及びエルゴチオネインの製造方法
JP6263672B1 (ja) 2016-02-29 2018-01-17 長瀬産業株式会社 エルゴチオネインの発酵生産
JP6277215B2 (ja) 2016-03-10 2018-02-07 株式会社三共 遊技機

Also Published As

Publication number Publication date
EP4534673A1 (en) 2025-04-09
KR20250007610A (ko) 2025-01-14
WO2023234307A1 (ja) 2023-12-07
JPWO2023234307A1 (https=) 2023-12-07
CN119343451A (zh) 2025-01-21

Similar Documents

Publication Publication Date Title
CN105026548B (zh) D-葡萄糖二酸生产菌及d-葡萄糖二酸的制造方法
TWI633190B (zh) 比利比洛邊(pyripyropene)的製造方法
TWI503412B (zh) 保持大規模基因組重複之麴菌及其應用
WO2022253815A1 (en) Methods for producing betalains in yeast
CN116426499A (zh) 一种甲基转移酶突变体、生物材料和应用
CN104130967B (zh) 一株共表达l‑乳酸脱氢酶和甲酸脱氢酶的大肠杆菌及其构建方法与应用
JP2011239681A (ja) 麹菌アルカリプロテアーゼプロモーター
TW202405183A (zh) 經修飾以增加麥角硫醇生產力之核酸及經基因修飾之微生物
JP2016154483A (ja) プロテインキナーゼ遺伝子変異株を利用した酵素類の製造方法
JPWO2016076159A6 (ja) シス−5−ヒドロキシ−l−ピペコリン酸の製造方法
JPWO2016076159A1 (ja) シス−5−ヒドロキシ−l−ピペコリン酸の製造方法
JP5367300B2 (ja) 麹菌の分生子形成に関与する遺伝子、及び、麹菌の分生子形成能を増大させる方法
WO2020125531A1 (zh) 一种螺旋霉素产生菌、可利霉素产生菌、构建方法、应用及提高产物产量的方法
JP6181971B2 (ja) 芳香族化合物の製造方法
US6916641B2 (en) (R)-2-hydroxy-3-phenylpropionate (d-phenyllactate) dehydrogenase and gene encoding the same
CN112055751B (zh) 修饰型酯酶和其用途
CN111454338B (zh) 塞普霉素前体肽的突变体、其应用及制得的塞普霉素类似物
JP5126707B2 (ja) α−ヒドロキシアシルピリジンの製造方法
WO2025244033A1 (ja) 色素合成抑制によるキサントキノジンの高生産化方法
윤혜리 CRISPR/Cas9 System for Efficient Genome Editing in Filamentous Fungi Monascus ruber Based on PacBio SMRT Sequencing
KR100674092B1 (ko) 내열성 티로신 페놀리아제 변이체 및 그 제조방법
CN121950850A (zh) torrubiellin类化合物生物合成基因簇及其应用
JP5813073B2 (ja) シクロピアゾン酸非生産形質転換体及びその作製方法
CN117757826A (zh) 短链脱氢酶的重组表达质粒、重组基因工程菌及其应用
JP6445884B2 (ja) 抗菌物質