CN119343451A - 以提高麦角硫因生产性的方式改变的核酸、以及基因改变的微生物 - Google Patents

以提高麦角硫因生产性的方式改变的核酸、以及基因改变的微生物 Download PDF

Info

Publication number
CN119343451A
CN119343451A CN202380043295.8A CN202380043295A CN119343451A CN 119343451 A CN119343451 A CN 119343451A CN 202380043295 A CN202380043295 A CN 202380043295A CN 119343451 A CN119343451 A CN 119343451A
Authority
CN
China
Prior art keywords
seq
region
amino acid
ergothioneine
aspergillus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202380043295.8A
Other languages
English (en)
Chinese (zh)
Inventor
田岛辽子
市川惠一
伊藤考太郎
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kikkoman Corp
Original Assignee
Kikkoman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kikkoman Corp filed Critical Kikkoman Corp
Publication of CN119343451A publication Critical patent/CN119343451A/zh
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/38Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN202380043295.8A 2022-05-31 2023-05-30 以提高麦角硫因生产性的方式改变的核酸、以及基因改变的微生物 Pending CN119343451A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2022-089120 2022-05-31
JP2022089120 2022-05-31
JP2022112588 2022-07-13
JP2022-112588 2022-07-13
PCT/JP2023/020131 WO2023234307A1 (ja) 2022-05-31 2023-05-30 エルゴチオネイン生産性を高めるように改変された核酸、並びに遺伝子改変された微生物

Publications (1)

Publication Number Publication Date
CN119343451A true CN119343451A (zh) 2025-01-21

Family

ID=89024879

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202380043295.8A Pending CN119343451A (zh) 2022-05-31 2023-05-30 以提高麦角硫因生产性的方式改变的核酸、以及基因改变的微生物

Country Status (6)

Country Link
EP (1) EP4534673A1 (https=)
JP (1) JPWO2023234307A1 (https=)
KR (1) KR20250007610A (https=)
CN (1) CN119343451A (https=)
TW (1) TW202405183A (https=)
WO (1) WO2023234307A1 (https=)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2707087B1 (fr) 1993-06-28 1995-10-13 Bioxytech Nouveau procédé de préparation de l'ergothionéine.
WO2016104437A1 (ja) 2014-12-22 2016-06-30 国立大学法人 岡山大学 エルゴチオネインの産生方法
WO2016121285A1 (ja) * 2015-01-30 2016-08-04 キッコーマン株式会社 エルゴチオネイン生産能が増強された形質転換糸状菌及びエルゴチオネインの製造方法
JP6263672B1 (ja) 2016-02-29 2018-01-17 長瀬産業株式会社 エルゴチオネインの発酵生産
JP6277215B2 (ja) 2016-03-10 2018-02-07 株式会社三共 遊技機

Also Published As

Publication number Publication date
EP4534673A1 (en) 2025-04-09
TW202405183A (zh) 2024-02-01
KR20250007610A (ko) 2025-01-14
WO2023234307A1 (ja) 2023-12-07
JPWO2023234307A1 (https=) 2023-12-07

Similar Documents

Publication Publication Date Title
Daba et al. The ancient koji mold (Aspergillus oryzae) as a modern biotechnological tool
Brown et al. Identification of a 12-gene fusaric acid biosynthetic gene cluster in Fusarium species through comparative and functional genomics
CN105026548B (zh) D-葡萄糖二酸生产菌及d-葡萄糖二酸的制造方法
KR101929239B1 (ko) Rgen rnp를 이용한 미세조류의 교정 방법
Seo et al. Isolation of the putative biosynthetic gene cluster of 1-deoxynojirimycin by Bacillus amyloliquefaciens 140N, its production and application to the fermentation of soybean paste
US20240309412A1 (en) Methods for producing betalains in yeast
CN105018357B (zh) 长链二元酸生产菌株及其制备方法和应用
Cleere et al. New colours for old in the blue-cheese fungus Penicillium roqueforti
KR101187081B1 (ko) 지질생산균의 취득방법
JP3910634B2 (ja) Pf1022物質を産生する形質転換体、及び糸状菌綱に属する菌の形質転換方法
CN108795970B (zh) 构巢曲霉异源表达系统的构建及其应用
JPWO1997000944A1 (ja) Pf1022物質を産生する形質転換体、及び糸状菌綱に属する菌の形質転換方法
CN119343451A (zh) 以提高麦角硫因生产性的方式改变的核酸、以及基因改变的微生物
CN113215121B (zh) 一种高效异源合成罗汉果甜苷v前体的方法
Yamamoto et al. Analysis of genomic characteristics and their influence on metabolism in Aspergillus luchuensis albino mutants using genome sequencing
JP6579862B2 (ja) レンチナン含量が高いシイタケ
KR101549152B1 (ko) 대맥장 유래의 리조푸스 오리제 dm07 균주
JP6830603B2 (ja) アスコクロリン及びイリシコリンaの製造方法
KR20190052815A (ko) Mat1-1 교배형 유전자를 갖는 아스페르길루스 루추엔시스 신규 미생물 및 이의 용도
JP3942718B2 (ja) 酒類、食品の製造方法
JP6181971B2 (ja) 芳香族化合物の製造方法
JP2018064484A (ja) 麹菌による加水分解酵素の大量生産方法
CN102516374A (zh) 用于四霉素生物合成的蛋白系统及编码其的基因簇
KR100777231B1 (ko) β-지랄레놀 대량 생산균주[KCCM 10795P] 및 이를이용한 β-지랄레놀 생산방법
WO2025244033A1 (ja) 色素合成抑制によるキサントキノジンの高生産化方法

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination