KR20250007610A - 에르고티오네인 생산성을 높이도록 개변된 핵산, 및 유전자 개변된 미생물 - Google Patents

에르고티오네인 생산성을 높이도록 개변된 핵산, 및 유전자 개변된 미생물 Download PDF

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KR20250007610A
KR20250007610A KR1020247039586A KR20247039586A KR20250007610A KR 20250007610 A KR20250007610 A KR 20250007610A KR 1020247039586 A KR1020247039586 A KR 1020247039586A KR 20247039586 A KR20247039586 A KR 20247039586A KR 20250007610 A KR20250007610 A KR 20250007610A
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ergothioneine
amino acid
sequence
nucleic acid
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Korean (ko)
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료코 다지마
게이이치 이치카와
고타로 이토
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기꼬만 가부시키가이샤
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/38Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020247039586A 2022-05-31 2023-05-30 에르고티오네인 생산성을 높이도록 개변된 핵산, 및 유전자 개변된 미생물 Pending KR20250007610A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JPJP-P-2022-089120 2022-05-31
JP2022089120 2022-05-31
JP2022112588 2022-07-13
JPJP-P-2022-112588 2022-07-13
PCT/JP2023/020131 WO2023234307A1 (ja) 2022-05-31 2023-05-30 エルゴチオネイン生産性を高めるように改変された核酸、並びに遺伝子改変された微生物

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KR20250007610A true KR20250007610A (ko) 2025-01-14

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KR1020247039586A Pending KR20250007610A (ko) 2022-05-31 2023-05-30 에르고티오네인 생산성을 높이도록 개변된 핵산, 및 유전자 개변된 미생물

Country Status (6)

Country Link
EP (1) EP4534673A1 (https=)
JP (1) JPWO2023234307A1 (https=)
KR (1) KR20250007610A (https=)
CN (1) CN119343451A (https=)
TW (1) TW202405183A (https=)
WO (1) WO2023234307A1 (https=)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006160748A (ja) 1993-06-28 2006-06-22 Oxis Isle Of Man Ltd エルゴチオネインの新規合成方法
JP2016104437A (ja) 2016-03-10 2016-06-09 株式会社三共 遊技機
WO2017150304A1 (ja) 2016-02-29 2017-09-08 長瀬産業株式会社 エルゴチオネインの発酵生産

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016104437A1 (ja) 2014-12-22 2016-06-30 国立大学法人 岡山大学 エルゴチオネインの産生方法
WO2016121285A1 (ja) * 2015-01-30 2016-08-04 キッコーマン株式会社 エルゴチオネイン生産能が増強された形質転換糸状菌及びエルゴチオネインの製造方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006160748A (ja) 1993-06-28 2006-06-22 Oxis Isle Of Man Ltd エルゴチオネインの新規合成方法
WO2017150304A1 (ja) 2016-02-29 2017-09-08 長瀬産業株式会社 エルゴチオネインの発酵生産
JP2016104437A (ja) 2016-03-10 2016-06-09 株式会社三共 遊技機

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
비특허문헌 1: PLOS One 2014 vol.9(5) e97774

Also Published As

Publication number Publication date
EP4534673A1 (en) 2025-04-09
TW202405183A (zh) 2024-02-01
WO2023234307A1 (ja) 2023-12-07
JPWO2023234307A1 (https=) 2023-12-07
CN119343451A (zh) 2025-01-21

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Patent event date: 20241127

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