TW202027617A - 補虛損保健品組合物及其製備方法和其應用 - Google Patents
補虛損保健品組合物及其製備方法和其應用 Download PDFInfo
- Publication number
- TW202027617A TW202027617A TW108136499A TW108136499A TW202027617A TW 202027617 A TW202027617 A TW 202027617A TW 108136499 A TW108136499 A TW 108136499A TW 108136499 A TW108136499 A TW 108136499A TW 202027617 A TW202027617 A TW 202027617A
- Authority
- TW
- Taiwan
- Prior art keywords
- parts
- seeds
- product composition
- deficiency
- preparing
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 109
- 230000036541 health Effects 0.000 title claims abstract description 65
- 230000007812 deficiency Effects 0.000 title claims abstract description 23
- 238000002360 preparation method Methods 0.000 title claims abstract description 18
- 230000001502 supplementing effect Effects 0.000 title claims abstract 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 72
- 239000000843 powder Substances 0.000 claims abstract description 28
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims abstract description 26
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 22
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 claims abstract description 17
- 239000002994 raw material Substances 0.000 claims abstract description 17
- 235000013311 vegetables Nutrition 0.000 claims abstract description 14
- 239000012535 impurity Substances 0.000 claims abstract description 13
- 239000008213 purified water Substances 0.000 claims abstract description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 13
- 238000000034 method Methods 0.000 claims abstract description 9
- 238000004108 freeze drying Methods 0.000 claims abstract description 3
- 239000000284 extract Substances 0.000 claims description 54
- 230000001256 tonic effect Effects 0.000 claims description 40
- 241000234282 Allium Species 0.000 claims description 24
- 235000002732 Allium cepa var. cepa Nutrition 0.000 claims description 22
- 235000013361 beverage Nutrition 0.000 claims description 18
- 240000002234 Allium sativum Species 0.000 claims description 15
- 235000004611 garlic Nutrition 0.000 claims description 15
- 235000008331 Pinus X rigitaeda Nutrition 0.000 claims description 13
- 235000011613 Pinus brutia Nutrition 0.000 claims description 13
- 241000018646 Pinus brutia Species 0.000 claims description 13
- 240000007087 Apium graveolens Species 0.000 claims description 12
- 235000015849 Apium graveolens Dulce Group Nutrition 0.000 claims description 12
- 235000010591 Appio Nutrition 0.000 claims description 12
- 239000003814 drug Substances 0.000 claims description 12
- 230000003204 osmotic effect Effects 0.000 claims description 11
- 230000002441 reversible effect Effects 0.000 claims description 11
- 235000005254 Allium ampeloprasum Nutrition 0.000 claims description 10
- 240000006108 Allium ampeloprasum Species 0.000 claims description 10
- 235000013599 spices Nutrition 0.000 claims description 10
- 235000002787 Coriandrum sativum Nutrition 0.000 claims description 9
- 244000269722 Thea sinensis Species 0.000 claims description 9
- 235000003095 Vaccinium corymbosum Nutrition 0.000 claims description 9
- 235000017537 Vaccinium myrtillus Nutrition 0.000 claims description 9
- 235000021014 blueberries Nutrition 0.000 claims description 9
- 241000233866 Fungi Species 0.000 claims description 8
- 240000000851 Vaccinium corymbosum Species 0.000 claims description 8
- 229920002472 Starch Polymers 0.000 claims description 7
- 244000299461 Theobroma cacao Species 0.000 claims description 7
- 239000003795 chemical substances by application Substances 0.000 claims description 7
- 235000019698 starch Nutrition 0.000 claims description 7
- 239000008107 starch Substances 0.000 claims description 7
- 235000002566 Capsicum Nutrition 0.000 claims description 6
- 235000005979 Citrus limon Nutrition 0.000 claims description 6
- 244000131522 Citrus pyriformis Species 0.000 claims description 6
- 239000006002 Pepper Substances 0.000 claims description 6
- 235000016761 Piper aduncum Nutrition 0.000 claims description 6
- 240000003889 Piper guineense Species 0.000 claims description 6
- 235000017804 Piper guineense Nutrition 0.000 claims description 6
- 235000008184 Piper nigrum Nutrition 0.000 claims description 6
- 240000001890 Ribes hudsonianum Species 0.000 claims description 6
- 235000016954 Ribes hudsonianum Nutrition 0.000 claims description 6
- 235000001466 Ribes nigrum Nutrition 0.000 claims description 6
- 244000018436 Coriandrum sativum Species 0.000 claims description 5
- 235000006025 Durio zibethinus Nutrition 0.000 claims description 5
- 240000000716 Durio zibethinus Species 0.000 claims description 5
- 241000219094 Vitaceae Species 0.000 claims description 5
- 235000021021 grapes Nutrition 0.000 claims description 5
- 240000004507 Abelmoschus esculentus Species 0.000 claims description 4
- 244000144725 Amygdalus communis Species 0.000 claims description 4
- 244000144730 Amygdalus persica Species 0.000 claims description 4
- 244000099147 Ananas comosus Species 0.000 claims description 4
- 235000007119 Ananas comosus Nutrition 0.000 claims description 4
- 241000167854 Bourreria succulenta Species 0.000 claims description 4
- 235000003255 Carthamus tinctorius Nutrition 0.000 claims description 4
- 244000020518 Carthamus tinctorius Species 0.000 claims description 4
- 244000223760 Cinnamomum zeylanicum Species 0.000 claims description 4
- 235000013162 Cocos nucifera Nutrition 0.000 claims description 4
- 244000060011 Cocos nucifera Species 0.000 claims description 4
- 235000009917 Crataegus X brevipes Nutrition 0.000 claims description 4
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 claims description 4
- 235000009685 Crataegus X maligna Nutrition 0.000 claims description 4
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 claims description 4
- 235000009486 Crataegus bullatus Nutrition 0.000 claims description 4
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 claims description 4
- 235000009682 Crataegus limnophila Nutrition 0.000 claims description 4
- 240000000171 Crataegus monogyna Species 0.000 claims description 4
- 235000004423 Crataegus monogyna Nutrition 0.000 claims description 4
- 235000002313 Crataegus paludosa Nutrition 0.000 claims description 4
- 235000009840 Crataegus x incaedua Nutrition 0.000 claims description 4
- 240000001008 Dimocarpus longan Species 0.000 claims description 4
- 235000000235 Euphoria longan Nutrition 0.000 claims description 4
- 235000014693 Fagopyrum tataricum Nutrition 0.000 claims description 4
- 244000130270 Fagopyrum tataricum Species 0.000 claims description 4
- 240000009088 Fragaria x ananassa Species 0.000 claims description 4
- 240000000950 Hippophae rhamnoides Species 0.000 claims description 4
- 235000003145 Hippophae rhamnoides Nutrition 0.000 claims description 4
- 235000018481 Hylocereus undatus Nutrition 0.000 claims description 4
- 244000157072 Hylocereus undatus Species 0.000 claims description 4
- 235000008227 Illicium verum Nutrition 0.000 claims description 4
- 240000007232 Illicium verum Species 0.000 claims description 4
- 240000007049 Juglans regia Species 0.000 claims description 4
- 235000009496 Juglans regia Nutrition 0.000 claims description 4
- 235000000421 Lepidium meyenii Nutrition 0.000 claims description 4
- 240000000759 Lepidium meyenii Species 0.000 claims description 4
- 241000408747 Lepomis gibbosus Species 0.000 claims description 4
- 244000108452 Litchi chinensis Species 0.000 claims description 4
- 244000241838 Lycium barbarum Species 0.000 claims description 4
- 235000015459 Lycium barbarum Nutrition 0.000 claims description 4
- 235000015468 Lycium chinense Nutrition 0.000 claims description 4
- 235000007688 Lycopersicon esculentum Nutrition 0.000 claims description 4
- 235000009811 Momordica charantia Nutrition 0.000 claims description 4
- 244000131360 Morinda citrifolia Species 0.000 claims description 4
- 244000179886 Moringa oleifera Species 0.000 claims description 4
- 235000011347 Moringa oleifera Nutrition 0.000 claims description 4
- 235000008708 Morus alba Nutrition 0.000 claims description 4
- 240000000249 Morus alba Species 0.000 claims description 4
- 235000015742 Nephelium litchi Nutrition 0.000 claims description 4
- 235000006484 Paeonia officinalis Nutrition 0.000 claims description 4
- 244000170916 Paeonia officinalis Species 0.000 claims description 4
- 235000000370 Passiflora edulis Nutrition 0.000 claims description 4
- 244000288157 Passiflora edulis Species 0.000 claims description 4
- 235000004347 Perilla Nutrition 0.000 claims description 4
- 244000124853 Perilla frutescens Species 0.000 claims description 4
- 235000010627 Phaseolus vulgaris Nutrition 0.000 claims description 4
- 244000046052 Phaseolus vulgaris Species 0.000 claims description 4
- 235000003406 Polymnia sonchifolia Nutrition 0.000 claims description 4
- 244000134540 Polymnia sonchifolia Species 0.000 claims description 4
- 235000006040 Prunus persica var persica Nutrition 0.000 claims description 4
- 235000003434 Sesamum indicum Nutrition 0.000 claims description 4
- 244000040738 Sesamum orientale Species 0.000 claims description 4
- 241000533293 Sesbania emerus Species 0.000 claims description 4
- 240000003768 Solanum lycopersicum Species 0.000 claims description 4
- 235000016639 Syzygium aromaticum Nutrition 0.000 claims description 4
- 244000223014 Syzygium aromaticum Species 0.000 claims description 4
- 235000009470 Theobroma cacao Nutrition 0.000 claims description 4
- 235000008322 Trichosanthes cucumerina Nutrition 0.000 claims description 4
- 244000078912 Trichosanthes cucumerina Species 0.000 claims description 4
- 235000006886 Zingiber officinale Nutrition 0.000 claims description 4
- 244000273928 Zingiber officinale Species 0.000 claims description 4
- 235000020224 almond Nutrition 0.000 claims description 4
- 235000019693 cherries Nutrition 0.000 claims description 4
- 235000017803 cinnamon Nutrition 0.000 claims description 4
- 235000008397 ginger Nutrition 0.000 claims description 4
- 235000021384 green leafy vegetables Nutrition 0.000 claims description 4
- 238000002386 leaching Methods 0.000 claims description 4
- 235000012902 lepidium meyenii Nutrition 0.000 claims description 4
- 235000013557 nattō Nutrition 0.000 claims description 4
- 235000017524 noni Nutrition 0.000 claims description 4
- 235000020236 pumpkin seed Nutrition 0.000 claims description 4
- 235000020234 walnut Nutrition 0.000 claims description 4
- 235000007319 Avena orientalis Nutrition 0.000 claims description 3
- 244000075850 Avena orientalis Species 0.000 claims description 3
- 240000009023 Myrrhis odorata Species 0.000 claims description 3
- 235000007265 Myrrhis odorata Nutrition 0.000 claims description 3
- 235000012550 Pimpinella anisum Nutrition 0.000 claims description 3
- 235000019219 chocolate Nutrition 0.000 claims description 3
- 235000014571 nuts Nutrition 0.000 claims description 3
- 238000001556 precipitation Methods 0.000 claims description 3
- 235000016623 Fragaria vesca Nutrition 0.000 claims description 2
- 235000011363 Fragaria x ananassa Nutrition 0.000 claims description 2
- 240000001949 Taraxacum officinale Species 0.000 claims description 2
- 241000203475 Neopanax arboreus Species 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000008247 solid mixture Substances 0.000 abstract description 22
- 210000003734 kidney Anatomy 0.000 abstract description 21
- 239000007788 liquid Substances 0.000 abstract description 17
- 230000000694 effects Effects 0.000 abstract description 16
- 241000245665 Taraxacum Species 0.000 abstract description 15
- 238000000605 extraction Methods 0.000 abstract description 9
- 238000005728 strengthening Methods 0.000 abstract description 7
- 231100000331 toxic Toxicity 0.000 abstract description 5
- 230000002588 toxic effect Effects 0.000 abstract description 5
- 238000001914 filtration Methods 0.000 abstract description 2
- 239000005556 hormone Substances 0.000 abstract description 2
- 229940088597 hormone Drugs 0.000 abstract description 2
- 238000002156 mixing Methods 0.000 abstract 1
- 239000000047 product Substances 0.000 description 59
- 235000002639 sodium chloride Nutrition 0.000 description 24
- 150000003839 salts Chemical class 0.000 description 20
- 235000015872 dietary supplement Nutrition 0.000 description 17
- 235000000346 sugar Nutrition 0.000 description 17
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 12
- 239000007787 solid Substances 0.000 description 12
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 10
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 10
- 239000000796 flavoring agent Substances 0.000 description 10
- 210000004185 liver Anatomy 0.000 description 10
- 239000008280 blood Substances 0.000 description 9
- 210000004369 blood Anatomy 0.000 description 9
- 238000003756 stirring Methods 0.000 description 9
- 235000013305 food Nutrition 0.000 description 8
- 235000013355 food flavoring agent Nutrition 0.000 description 8
- 229920000858 Cyclodextrin Polymers 0.000 description 7
- 229940079593 drug Drugs 0.000 description 7
- 230000006870 function Effects 0.000 description 7
- 210000003205 muscle Anatomy 0.000 description 7
- 208000024891 symptom Diseases 0.000 description 7
- 239000001116 FEMA 4028 Substances 0.000 description 6
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical group OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 description 6
- 235000011175 beta-cyclodextrine Nutrition 0.000 description 6
- 229960004853 betadex Drugs 0.000 description 6
- 229910052742 iron Inorganic materials 0.000 description 6
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 5
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 5
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 5
- 229930003268 Vitamin C Natural products 0.000 description 5
- 239000011575 calcium Substances 0.000 description 5
- 229910052791 calcium Inorganic materials 0.000 description 5
- 235000001465 calcium Nutrition 0.000 description 5
- 239000002398 materia medica Substances 0.000 description 5
- 239000011574 phosphorus Substances 0.000 description 5
- 229910052698 phosphorus Inorganic materials 0.000 description 5
- 235000018102 proteins Nutrition 0.000 description 5
- 108090000623 proteins and genes Proteins 0.000 description 5
- 102000004169 proteins and genes Human genes 0.000 description 5
- 235000017557 sodium bicarbonate Nutrition 0.000 description 5
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 5
- 210000002784 stomach Anatomy 0.000 description 5
- 235000019154 vitamin C Nutrition 0.000 description 5
- 239000011718 vitamin C Substances 0.000 description 5
- 241000208308 Coriandrum Species 0.000 description 4
- 229930091371 Fructose Natural products 0.000 description 4
- 239000005715 Fructose Substances 0.000 description 4
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 4
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 229930006000 Sucrose Natural products 0.000 description 4
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 4
- 235000010208 anthocyanin Nutrition 0.000 description 4
- 239000004410 anthocyanin Substances 0.000 description 4
- 229930002877 anthocyanin Natural products 0.000 description 4
- 150000004636 anthocyanins Chemical class 0.000 description 4
- 210000000988 bone and bone Anatomy 0.000 description 4
- 210000002216 heart Anatomy 0.000 description 4
- 239000011435 rock Substances 0.000 description 4
- 239000011780 sodium chloride Substances 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 208000011580 syndromic disease Diseases 0.000 description 4
- 229930003231 vitamin Natural products 0.000 description 4
- 235000013343 vitamin Nutrition 0.000 description 4
- 239000011782 vitamin Substances 0.000 description 4
- 229940088594 vitamin Drugs 0.000 description 4
- 244000291564 Allium cepa Species 0.000 description 3
- 235000001270 Allium sibiricum Nutrition 0.000 description 3
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- 244000228451 Stevia rebaudiana Species 0.000 description 3
- 230000036772 blood pressure Effects 0.000 description 3
- 238000001816 cooling Methods 0.000 description 3
- 235000003599 food sweetener Nutrition 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 239000003163 gonadal steroid hormone Substances 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 150000007524 organic acids Chemical class 0.000 description 3
- 235000005985 organic acids Nutrition 0.000 description 3
- HELXLJCILKEWJH-NCGAPWICSA-N rebaudioside A Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HELXLJCILKEWJH-NCGAPWICSA-N 0.000 description 3
- 229960002477 riboflavin Drugs 0.000 description 3
- 210000000952 spleen Anatomy 0.000 description 3
- 239000013589 supplement Substances 0.000 description 3
- 239000003765 sweetening agent Substances 0.000 description 3
- 229960003495 thiamine Drugs 0.000 description 3
- KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 description 3
- 244000295724 Allium chinense Species 0.000 description 2
- 235000016790 Allium chinense Nutrition 0.000 description 2
- 241000208173 Apiaceae Species 0.000 description 2
- 206010003210 Arteriosclerosis Diseases 0.000 description 2
- HJXMNVQARNZTEE-UHFFFAOYSA-N Butylphthalide Chemical compound C1=CC=C2C(CCCC)OC(=O)C2=C1 HJXMNVQARNZTEE-UHFFFAOYSA-N 0.000 description 2
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 description 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 description 2
- 240000004371 Panax ginseng Species 0.000 description 2
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 2
- 235000003140 Panax quinquefolius Nutrition 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 2
- 208000009205 Tinnitus Diseases 0.000 description 2
- 229930003451 Vitamin B1 Natural products 0.000 description 2
- 229930003471 Vitamin B2 Natural products 0.000 description 2
- 208000031975 Yang Deficiency Diseases 0.000 description 2
- 235000009932 Zanthoxylum simulans Nutrition 0.000 description 2
- 244000089698 Zanthoxylum simulans Species 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 208000011775 arteriosclerosis disease Diseases 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 230000005189 cardiac health Effects 0.000 description 2
- 150000001746 carotenes Chemical class 0.000 description 2
- 235000005473 carotenes Nutrition 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 238000001784 detoxification Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 230000002526 effect on cardiovascular system Effects 0.000 description 2
- 235000019197 fats Nutrition 0.000 description 2
- 229930003935 flavonoid Natural products 0.000 description 2
- 150000002215 flavonoids Chemical class 0.000 description 2
- 235000017173 flavonoids Nutrition 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 235000012055 fruits and vegetables Nutrition 0.000 description 2
- 235000008434 ginseng Nutrition 0.000 description 2
- 235000012907 honey Nutrition 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 210000003127 knee Anatomy 0.000 description 2
- 150000002596 lactones Chemical class 0.000 description 2
- CDOSHBSSFJOMGT-UHFFFAOYSA-N linalool Chemical compound CC(C)=CCCC(C)(O)C=C CDOSHBSSFJOMGT-UHFFFAOYSA-N 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 239000011777 magnesium Substances 0.000 description 2
- 229910052749 magnesium Inorganic materials 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 206010029446 nocturia Diseases 0.000 description 2
- 235000013824 polyphenols Nutrition 0.000 description 2
- 239000011591 potassium Substances 0.000 description 2
- 229910052700 potassium Inorganic materials 0.000 description 2
- 235000007686 potassium Nutrition 0.000 description 2
- 238000002203 pretreatment Methods 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 238000010791 quenching Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 230000001568 sexual effect Effects 0.000 description 2
- 235000021012 strawberries Nutrition 0.000 description 2
- 230000035922 thirst Effects 0.000 description 2
- 231100000886 tinnitus Toxicity 0.000 description 2
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 2
- 235000010374 vitamin B1 Nutrition 0.000 description 2
- 239000011691 vitamin B1 Substances 0.000 description 2
- 235000019164 vitamin B2 Nutrition 0.000 description 2
- 239000011716 vitamin B2 Substances 0.000 description 2
- 239000000341 volatile oil Substances 0.000 description 2
- 239000001490 (3R)-3,7-dimethylocta-1,6-dien-3-ol Substances 0.000 description 1
- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 description 1
- CDOSHBSSFJOMGT-JTQLQIEISA-N (R)-linalool Natural products CC(C)=CCC[C@@](C)(O)C=C CDOSHBSSFJOMGT-JTQLQIEISA-N 0.000 description 1
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- WBZFUFAFFUEMEI-UHFFFAOYSA-M Acesulfame k Chemical compound [K+].CC1=CC(=O)[N-]S(=O)(=O)O1 WBZFUFAFFUEMEI-UHFFFAOYSA-M 0.000 description 1
- JDLKFOPOAOFWQN-VIFPVBQESA-N Allicin Natural products C=CCS[S@](=O)CC=C JDLKFOPOAOFWQN-VIFPVBQESA-N 0.000 description 1
- 108010092760 Alliin lyase Proteins 0.000 description 1
- 235000018714 Allium canadense Nutrition 0.000 description 1
- 235000010167 Allium cepa var aggregatum Nutrition 0.000 description 1
- 241000383638 Allium nigrum Species 0.000 description 1
- 235000011403 Allium vineale Nutrition 0.000 description 1
- 235000011437 Amygdalus communis Nutrition 0.000 description 1
- 239000004475 Arginine Substances 0.000 description 1
- 241000208838 Asteraceae Species 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 241001107116 Castanospermum australe Species 0.000 description 1
- 240000004307 Citrus medica Species 0.000 description 1
- UDIPTWFVPPPURJ-UHFFFAOYSA-M Cyclamate Chemical compound [Na+].[O-]S(=O)(=O)NC1CCCCC1 UDIPTWFVPPPURJ-UHFFFAOYSA-M 0.000 description 1
- 235000015489 Emblica officinalis Nutrition 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 208000010201 Exanthema Diseases 0.000 description 1
- 240000006927 Foeniculum vulgare Species 0.000 description 1
- 235000004204 Foeniculum vulgare Nutrition 0.000 description 1
- 201000005569 Gout Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010022971 Iron Deficiencies Diseases 0.000 description 1
- 241000234280 Liliaceae Species 0.000 description 1
- 244000179970 Monarda didyma Species 0.000 description 1
- 235000010672 Monarda didyma Nutrition 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 240000008881 Oenanthe javanica Species 0.000 description 1
- 235000000365 Oenanthe javanica Nutrition 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 240000009120 Phyllanthus emblica Species 0.000 description 1
- 235000013559 Schnittsellerie Nutrition 0.000 description 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 1
- 206010041497 Spermatorrhoea Diseases 0.000 description 1
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 description 1
- 235000006468 Thea sinensis Nutrition 0.000 description 1
- JZRWCGZRTZMZEH-UHFFFAOYSA-N Thiamine Natural products CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 description 1
- 244000077233 Vaccinium uliginosum Species 0.000 description 1
- 235000009499 Vanilla fragrans Nutrition 0.000 description 1
- 244000263375 Vanilla tahitensis Species 0.000 description 1
- 235000012036 Vanilla tahitensis Nutrition 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 235000009754 Vitis X bourquina Nutrition 0.000 description 1
- 235000012333 Vitis X labruscana Nutrition 0.000 description 1
- 240000006365 Vitis vinifera Species 0.000 description 1
- 235000014787 Vitis vinifera Nutrition 0.000 description 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- WJEIYVAPNMUNIU-UHFFFAOYSA-N [Na].OC(O)=O Chemical compound [Na].OC(O)=O WJEIYVAPNMUNIU-UHFFFAOYSA-N 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 229960004998 acesulfame potassium Drugs 0.000 description 1
- 235000010358 acesulfame potassium Nutrition 0.000 description 1
- 239000000619 acesulfame-K Substances 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- JDLKFOPOAOFWQN-UHFFFAOYSA-N allicin Chemical compound C=CCSS(=O)CC=C JDLKFOPOAOFWQN-UHFFFAOYSA-N 0.000 description 1
- 235000010081 allicin Nutrition 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 235000008714 apigenin Nutrition 0.000 description 1
- XADJWCRESPGUTB-UHFFFAOYSA-N apigenin Natural products C1=CC(O)=CC=C1C1=CC(=O)C2=CC(O)=C(O)C=C2O1 XADJWCRESPGUTB-UHFFFAOYSA-N 0.000 description 1
- KZNIFHPLKGYRTM-UHFFFAOYSA-N apigenin Chemical compound C1=CC(O)=CC=C1C1=CC(=O)C2=C(O)C=C(O)C=C2O1 KZNIFHPLKGYRTM-UHFFFAOYSA-N 0.000 description 1
- 229940117893 apigenin Drugs 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 1
- 239000010692 aromatic oil Substances 0.000 description 1
- 230000037007 arousal Effects 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 235000021279 black bean Nutrition 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 210000004958 brain cell Anatomy 0.000 description 1
- 229950005197 butylphthalide Drugs 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 210000004351 coronary vessel Anatomy 0.000 description 1
- 229940109275 cyclamate Drugs 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 235000011869 dried fruits Nutrition 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 206010013663 drug dependence Diseases 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 235000021022 fresh fruits Nutrition 0.000 description 1
- 229910052732 germanium Inorganic materials 0.000 description 1
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 210000000777 hematopoietic system Anatomy 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 210000002414 leg Anatomy 0.000 description 1
- 208000027906 leg weakness Diseases 0.000 description 1
- 229930007744 linalool Natural products 0.000 description 1
- 229960004488 linolenic acid Drugs 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 230000008897 memory decline Effects 0.000 description 1
- 206010027175 memory impairment Diseases 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 150000008442 polyphenolic compounds Chemical class 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 206010036596 premature ejaculation Diseases 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 230000000171 quenching effect Effects 0.000 description 1
- 206010037844 rash Diseases 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000001223 reverse osmosis Methods 0.000 description 1
- 235000019192 riboflavin Nutrition 0.000 description 1
- 239000002151 riboflavin Substances 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 235000017709 saponins Nutrition 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 239000011669 selenium Substances 0.000 description 1
- 230000035946 sexual desire Effects 0.000 description 1
- 230000036299 sexual function Effects 0.000 description 1
- 210000002460 smooth muscle Anatomy 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 229940013618 stevioside Drugs 0.000 description 1
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 description 1
- 235000019202 steviosides Nutrition 0.000 description 1
- 208000011117 substance-related disease Diseases 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 150000003464 sulfur compounds Chemical class 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 235000019157 thiamine Nutrition 0.000 description 1
- 239000011721 thiamine Substances 0.000 description 1
- 150000003568 thioethers Chemical class 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 210000003556 vascular endothelial cell Anatomy 0.000 description 1
- 239000000052 vinegar Substances 0.000 description 1
- 235000021419 vinegar Nutrition 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 230000002618 waking effect Effects 0.000 description 1
- 108010027345 wheylin-1 peptide Proteins 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/235—Foeniculum (fennel)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/52—Juglandaceae (Walnut family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/31—Foods, ingredients or supplements having a functional effect on health having an effect on comfort perception and well-being
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/324—Foods, ingredients or supplements having a functional effect on health having an effect on the immune system
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2300/00—Processes
- A23V2300/50—Concentrating, enriching or enhancing in functional factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Nutrition Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Urology & Nephrology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Physiology (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Non-Alcoholic Beverages (AREA)
Abstract
本發明涉及一種補虛損保健品組合物及其製備方法和其應用，按質量份數計，製備該組合物所需的原料包括：蒲公英5份~40份、鱗莖菜類10份~120份、香辛葉菜類10份~100份、水果8份~16份。該補虛損保健品組合物的製備方法包括如下步驟：將蒲公英、鱗莖菜類、香辛葉菜類等原料粉碎、混合，得到固體混合物；將固體混合物加純化水浸提，過濾得到浸提汁；對浸提汁進行濃縮得到濃縮液；加乙醇對濃縮液進行沉澱除雜，得到精製液；對精製液進行包埋處理，得到提取液；將提取液冷凍乾燥處理，得到補虛損保健品組合物的凍乾粉。此方法製備得到的補虛損保健品組合物不含激素、無明顯毒副作用且具有補虛損、補腎壯陽的功效。
Description
本發明係涉及保健品領域，特別是涉及一種補虛損保健品組合物及其製備方法和其應用。
隨著人們生活節奏的不斷加快，工作和生活壓力不斷增加，處於亞健康狀態的人數也不斷增加。尤其是男性，人到中年，常常出現體力不支、肝腎陰虛及腎陽虛等症狀。這給患者帶來極大的精神壓力，甚至影響正常的家庭生活。
為此，患者常常需要尋求藥物說明。目前市場上銷售的補腎壯陽類藥物雖然種目繁多，但是大多數都含有性激素，或含有明顯的副作用，久服會產生藥物依賴，甚至危害身體健康。
基於此，有必要提供一種無明顯毒副作用且具有補虛損、補腎壯陽功效的補虛損保健品組合物。
此外，還提供一種補虛損保健品組合物的製備方法和其應用。
因此，為達上述目的，本發明提供一種補虛損保
健品組合物，按照質量份數計，製備該補虛損保健品組合物的原料包括：蒲公英5份~40份、鱗莖菜類10份~120份、香辛葉菜類10份~100份、水果8份~16份；其中，該鱗莖菜類選自蔥、洋蔥及蒜中至少一種，該香辛葉菜類選自韭菜、芹菜及芫荽中至少一種，該水果選自葡萄、藍莓、黑加侖、檸檬、橘子、橙子、荔枝、櫻桃、龍眼肉、草莓、菠蘿、椰子、火龍果、雪蓮果，榴槤、諾麗果、五指果及番茄中至少一種。
上述補虛損保健品組合物的原料均選自常見的蔬菜水果，不含性激素、無明顯毒副作用；並且發明人透過臨床試驗證實由上述原料製備得到的補虛損保健品組合物具有補虛損、補腎壯陽的功效。
在其中一個實施例中，按照質量份數計，製備該補虛損保健品組合物的原料還包括0份~6份的食用種子，該食用種子選自枸杞子、余甘子、沙棘子、燕麥、苦蕎麥、納豆、桑椹子、核桃仁、芝麻、牡丹花子、百香果、杏仁、桃仁、紅花子、紫蘇子、南瓜子、苦瓜籽、松籽、辣木籽、瑪卡籽、黃秋葵子、山楂、可可豆及咖啡豆中至少一種。
在其中一個實施例中，按照質量份數計，製備該補虛損保健品組合物的原料還包括0份~6份的茶籽金花菌和0份~6份的松花粉。
在其中一個實施例中，按照質量份數計，製備該補虛損保健品組合物的原料還包括0份~6份的香辛料，該香辛料選自薑、肉桂、茴香、八角、胡椒、香果、花椒及丁香中至少一種。
上述任一實施例的補虛損保健品組合物在製備保
健藥物、保健飲料或巧克力中的應用。
在其中一個實施例中，上述補虛損保健品組合物的製備方法，包括如下步驟：將製備該補虛損保健品組合物的原料粉碎、混合，然後在純化水中70℃~80℃下進行浸提處理，得到浸提汁。
在其中一個實施例中，在該浸提處理的步驟之後還包括如下步驟：將該浸提汁進行濃縮處理至相對密度為1.18~1.20，得到濃縮液；加入0.3%~6%的濃縮液體積的包埋劑進行包埋處理，得到提取液。
在其中一個實施例中，該濃縮處理時的反滲透壓為30kg/cm2~150kg/cm2，該包埋劑為β-環糊精或多孔澱粉。
在其中一個實施例中，在該濃縮處理的步驟之後，該包埋處理的步驟之前，還包括加入3倍濃縮液體積的乙醇溶液沉澱除雜得到精製液的步驟，該乙醇溶液中乙醇的體積百分含量高於70%。
在其中一個實施例中，在該包埋處理的步驟之後還包括在-70℃~-35℃的溫度下，將該提取液冷凍乾燥製成凍乾粉的步驟。
S110~S170‧‧‧步驟
第1圖為一實施例方式的保健品的製備方法流程圖。
為了便於理解本發明，下面將參照相關圖式對本發明進行更全面的描述。圖式中給出了本發明的較佳的實施
例。但是，本發明可以以許多不同的形式來實現，並不限於本文所描述的實施例。相反地，提供這些實施例的目的是使對本發明的公開內容的理解更加透徹全面。
除非另有定義，本文所使用的所有的技術和科學術語與屬於本發明的技術領域的技術人員通常理解的含義相同。本文中在本發明的說明書中所使用的術語只是為了描述具體的實施例的目的，不是旨在於限制本發明。
如第1圖所示，一實施方式的補虛損保健品組合物的製備方法，包括如下步驟：
步驟S110：按照質量份數計，將5份~40份的蒲公英、10份~120份的鱗莖菜類、10份~100份的香辛葉菜類、8份~16份的水果、0份~6份的食用種子、0份~6份的茶籽金花菌、0份~6份的松花粉及0份~6份的香辛料粉碎、混合，得到固體混合物。
其中，蒲公英是指菊科多年生草本植物蒲公英的整個全草。蒲公英，味甘、寒，無毒，歸肝，腎經。中醫經典記載其功用為清熱解毒，利尿通淋。《綱目》記載：“烏鬚髮，壯筋骨”；《醫林纂要》記載：“補脾和胃，養陰涼血，舒筋固齒，通乳益精”，又有“瀉火安土”之功；《本草求真》則認為其“能入陽明胃，厥陰肝，涼血解熱”；希雍曰“甘平之劑，能補肝腎”。
其中，鱗莖菜類選自蔥、洋蔥及蒜中至少一種。蔥，味辛，氣溫，入肺、胃、肝三經，其功用發表，通陽，解毒。並能通關節，通陽氣，發散風邪；又能達表和裡。蔥實則有溫腎，明目，治陽痿之功。蔥具有獨特的香辣素，蔥所含的
蘋果酸和磷酸糖能興奮神經，改善促進血循環。大蒜是指百合科蔥屬中以鱗芽構成鱗的草本植物，性溫，味辛辣，具有下氣，除風，散痛，消毒氣之功，大蒜中含有鐵、鎂、鍺和硒，還含有17種氨基酸，以精氨酸含量最高，占氨基酸總量的20.4%。大蒜還含有大蒜素，是蒜氨酸經蒜氨酸酶的作用而形成的一種揮發性硫化物。據研究，大蒜有降血壓，抗血小板聚集，抗動脈硬化和防癌等生理功效。大蒜中的植物殺菌素有較強殺菌作用。
需要說明的是，上述的蔥、洋蔥並不限於具體的品種，例如它還可以是漢蔥、胡蔥、茖蔥、山蔥、冬蔥等；也不限於具體的食用部位，例如它可以是蔥葉、蔥白、蔥花、蔥籽等。同樣地，上述的蒜也並不限於具體的品種，例如它可以是大蒜、黑蒜等；蒜也不限於具體的食用部位，例如它可以是蒜白、蒜苗、蒜薹等。
其中，香辛葉菜類選自韭菜、芹菜及芫荽中至少一種。韭菜，辛溫，入肝、胃、腎經。《本草拾遺》記載：“溫中，下氣，補虛，調和臟腑”。《日華子本草》記載：“止泄精，暖腰膝”。《中藥大辭典》記載：“溫中，行氣，散血，解毒”，“治陽虛腎冷，陽道不振，或腰膝冷痛，遺精夢泄”。韭菜中蛋白質、脂肪、碳水化合物含量較高，維生素含量豐富，並富含鈣、磷、鐵等礦物質，還含有揮發性精油和硫化物等成分，具有興奮神經等作用，亦含生物鹼、皂甙，可溫補肝腎，固精壯陽。芹菜是指傘形科芹屬中形成肥嫩葉柄的二年生草本植物。分為中國芹菜和西芹兩種。芹菜有平肝清熱的作用。芹菜含有維生素A、維生素B1、維生素B2、維生素C、鈣、鐵、磷等營養成分。芹菜含鐵量較多，是補充缺鐵的食療佳品。芹
菜含有芹菜苷，佛手苷內酯，揮發油及丁基苯酞等成分。芹菜中還含一種使平滑肌舒張的物質，有降壓和健腦等作用。芫荽為傘形花科芫荽屬中食用葉和嫰莖的一年生草本植物。芫荽有發汗透疹，消食下氣，醒脾和中的功用。芫荽含有鈣、磷、鐵、胡蘿蔔素、維生素C、硫胺素、核黃素，並含有芳香油類，如芳樟醇，異香豆酮A、B和香柑內酯等，是芳香物質的主要來源。
需要說明的是，上述的韭菜、芹菜及芫荽既不限於具體的品種，也不限於具體的食用部位等。
其中，水果選自葡萄、藍莓、黑加侖、檸檬、橘子、橙子、荔枝、櫻桃、龍眼肉、草莓、菠蘿、椰子、火龍果、雪蓮果，榴槤、諾麗果、五指果及番茄中至少一種。葡萄，甘酸、平，入肺、脾、腎經。《中藥大辭典》謂其：“補氣血，強筋骨，利小便”。《本經》記載：“主筋骨濕痹，益氣倍力，強志”。《滇南本草》記載：“大補氣血，舒筋活絡”。《隨息居飲食譜》記載：“補氣，滋腎液，益肝陰，強筋骨，止渴，安胎”。《陸川本草》記載：“滋養強壯，補血，強心利尿”。檸檬，《中藥大辭典》記述：“生津，止渴，袪暑，安胎”。《食物考》記述：“孕婦宜食，能安胎”，《綱目拾遺》記述：“下氣和胃”。檸檬能改善肌肉工作能力，防止疲勞和解除已有的疲勞。藍莓果膠含量很高，富含維生素C，含有微量元素錳，並且是花青素含量豐富的水果，在40餘種果蔬中的抗氧化能力排名第一。其所含的類黃素可防止腦細胞被自由基破壞。吃藍莓可以預防癌症和減緩衰老，提高老年人的平衡性和協調性，尤其對於記憶力衰退和運動神經，更有予防效果。此外藍莓有保護毛細血管，有益心臟健康，含有的多酚類物質，花青素等
成分，可增強人體免疫力。研究指出藍莓的有效成分花青素能透過血管內皮細胞來刺激一氧化氮的合成，從而改善男性勃起質量。黑加侖，又叫旱葡萄、紫梅、黑豆果等。果實富含花青素、酚類物質，含糖類，多種維生素和有機酸等，尤其維生素C含量極高，並含磷、鎂、鉀、鈣，其中鋅含量高。其種子中亞油酸含量高，有降壓、降血脂和抗動脈硬化等作用，另一種r-亞麻酸，是人體不能合成的特有成分，可起到抗心血管疾病的作用。果實有
腎益氣血的功用，其保健功效包括：予防痛風、貧血、水腫、關節炎、風濕、口腔咽喉疾患，對心腦血管，高血壓等有很好的效果。黑加侖有較高的藥用價值，可增強人體免疫力，抗衰老。橘子有開胃理氣等作用，含有鈣、磷、鐵、鉀、胡蘿蔔素、維生素B1、維生素B2、維生素C等，橘子中所含多種有機酸、維生素可興奮心臟，降低毛細血管的脆性對老年人及心血管病人具有保健意義。橙子可理氣，消食開胃，化痰，富含多種有機酸、維生素，對人體新陳代謝以及心臟十分有益。此外，橘橙中所含的黃酮類物質能擴張冠狀動脈，增加冠狀動脈血流量，是維護心臟健康的重要物質。
需要說明的是，上述的各種水果均不限於其形態，例如它們可以是鮮果、乾果或者果汁。
其中，所述食用種子選自枸杞子、余甘子、沙棘子、燕麥、苦蕎麥、納豆、桑椹子、核桃仁、芝麻、牡丹花子、百香果、杏仁、桃仁、紅花子、紫蘇子、南瓜子、苦瓜籽、松籽、辣木籽、瑪卡籽、黃秋葵子、山楂、可可豆及咖啡豆中至少一種。
其中，香辛料選自薑、肉桂、茴香、八角、胡椒、香果、花椒及丁香中至少一種。
步驟S120：加入800ml的純化水到上述固體混合物中，升溫到70℃~80℃浸提1h~2h，過濾得到浸提汁。
步驟S130：將上述浸提汁在在反滲透壓為30kg/cm2~150kg/cm2的壓力下，濃縮至相對密度為1.18~1.20的濃縮液。
步驟S140：往上述濃縮液中加入3倍濃縮液體積的乙醇溶液沉澱除雜，得到精製液。
其中，乙醇溶液中乙醇的體積百分含量高於70%。
步驟S150：往上述精製液中加入0.3%~6%的濃縮液體積的包埋劑，攪拌混合進行包埋處理，得到提取液。
其中，包埋劑選自β-環糊精及多孔澱粉中至少一種。
步驟S160：將上述提取液在-70℃~-35℃時冷凍乾燥，製成補虛損保健品組合物凍乾粉。
步驟S170：按照質量份數計，往上述提取液或者凍乾粉中添加0.01份~5份的甜味劑、0.01份~0.05份的食鹽、0.3份~0.5份的碳酸氫鈉及0.1份~0.3份的調味劑製成液體飲料或者固體飲料。
其中，甜味劑選自食品加工領域常用的甜味劑，如葡萄糖、紅糖、蜂蜜、白砂糖、冰糖、果糖、蛋白糖、甜菊糖、木糖醇、甜蜜素及安賽蜜中的至少一種。同樣地，調味劑也選用常用的調味劑產品，在此不再贅述。
需要說明的是，步驟S110~S150製備得到的提取液用於製備液體飲料；其中步驟S140可以省略，省略後，步驟
S150直接對步驟S130中的濃縮液進行包埋處理。步驟S160製備得到的凍乾粉用於製備固體飲料，也就是說，如果不需要製備固體飲料，就沒有步驟S160。步驟S170用於將步驟S150中的提取液製成保健品液體飲料，或者用於將步驟S160中的凍乾粉製成保健品固態飲料。
按上述補虛損保健品組合物的製備方法，透過將上述的各種原料按上述比例粉碎、混合，然後按相應的步驟處理製備得到液態或者固態的補虛損保健品組合物。將上述補虛損保健品組合物添加適量的食品添加劑，採用食品加工工藝可以用於製作保健藥物、保健飲料(保健醋、保健酒、酵素類等)或巧克力等產品。其中保健藥物的劑型為口服液、膠囊、丸劑、片劑、蜜膏劑等常用劑型。
上述補虛損保健品組合物的製備方法製備得到的補虛損保健品組合物的製作原料全部取自蔬菜、水果或藥食兩用材料，不含激素且無明顯的毒副作用。另外，經臨床試驗證明：上述補虛損保健品組合物還具有補虛損、補腎壯陽功效。
以下為實施例部分：
實施例1
本實施例的補虛損保健品組合物的製備過程如下：
(1)按照質量份數計，將25份蒲公英、35份蔥、10份韭菜、8份葡萄與藍莓和黑加侖的混合物、3份茶籽金花菌、3份松花粉、3份南瓜子與苦瓜籽和芝麻的混合物及3份薑粉碎、混合，得到固體混合物。
(2)加入800ml的純化水到上述固體混合物中，升溫到70℃浸提100min，過濾得到浸提汁。
(3)將上述浸提汁在反滲透壓為30kg/cm2的壓力下，濃縮至相對密度為1.18的濃縮液。
(4)往上述濃縮液中加入3倍濃縮液體積的乙醇溶液(乙醇體積百分含量為70%)沉澱除雜，得到精製液。
(5)往上述精製液中加入0.3%的濃縮液體積的β-環糊精，攪拌混合進行包埋處理，得到提取液。
(6)按照質量份數計，往上述提取液中加入3份葡萄糖、0.01份食鹽，升溫到76.6℃殺菌2min，調配製備得到補虛損保健品組合物液體飲料。
實施例2
本實施例的補虛損保健品組合物的製備過程如下：
(1)按照質量份數計，將30份蒲公英、10份蔥、10份韭菜、8份檸檬與橘子和橙子的混合物、3份茶籽金花菌、3份松花粉、3份枸杞子與余甘子和沙棘子的混合物及3份肉桂粉碎、混合，得到固體混合物。
(2)加入800ml的純化水到上述固體混合物中，升溫到70℃浸提100min，過濾得到浸提汁。
(3)將上述浸提汁在反滲透壓為100kg/cm2的壓力下，濃縮至相對密度為1.20的濃縮液。
(4)往上述濃縮液中加入3倍濃縮液體積乙醇溶
液(乙醇體積百分含量為75%)沉澱除雜，得到精製液。
(5)往上述精製液中加入0.6%的濃縮液體積的β-環糊精，攪拌混合進行包埋處理，得到提取液。
(6)將上述提取液在-70℃冷凍乾燥，製成補虛損保健品組合物凍乾粉。
(7)按照質量份數計，將5份紅糖，在60℃下烘乾12小時，粉碎後過60目篩，得到紅糖處理物；將0.1份食鹽在105℃烘乾3小時，室溫冷卻後過16目篩，得到食鹽處理物；在12℃將上述凍乾粉、紅糖處理物、食鹽處理物及0.1份香精混合，得到補虛損保健品組合物固體飲料。
實施例3
本實施例的補虛損保健品組合物的製備過程如下：
(1)按照質量份數計，將20份蒲公英、10份蔥、80份韭菜、14份荔枝與龍眼的混合物、6份松籽與辣木籽和瑪卡籽的混合物及3份茴香粉碎、混合，得到固體混合物。
(2)加入800ml的純化水到上述固體混合物中，升溫到70℃浸提60min，過濾得到浸提汁。
(3)將上述浸提汁在反滲透壓為150kg/cm2的壓力下，濃縮至相對密度為1.20的濃縮液。
(4)往上述濃縮液中加入3倍濃縮液體積的乙醇溶液(乙醇體積百分含量為75%)沉澱除雜，得到精製液。
(5)往上述精製液中加入1.5%的濃縮液體積的β-
環糊精，攪拌混合進行包埋處理，得到提取液。
(6)按照質量份數計，往上述提取液中加入3份葡萄糖、0.01份食鹽，升溫到93℃殺菌，殺菌3min，調配製備得到補虛損保健品組合物液體飲料。
實施例4
本實施例的補虛損保健品組合物的製備過程如下：
(1)按照質量份數計，將30份蒲公英、30份蔥、10份韭菜、11份櫻桃與草莓和番茄的混合物、6份茶籽金花菌及6份松花粉粉碎、混合，得到固體混合物。
(2)加入800ml的純化水到上述固體混合物中，升溫到75℃浸提120min，過濾得到浸提汁。
(3)將上述浸提汁在反滲透壓為80kg/cm2的壓力下，濃縮至相對密度為1.20的濃縮液。
(4)往上述濃縮液中加入3倍體積的乙醇溶液(乙醇體積百分含量為96%)沉澱除雜，得到精製液。
(5)往上述精製液中加入1.5%的β-環糊精，攪拌混合進行包埋處理，得到提取液。
(6)將上述提取液在-50℃冷凍乾燥，製成補虛損保健品組合物凍乾粉。
(7)按照質量份數計，將4份白砂糖，在60℃下烘乾12小時，粉碎後過60目篩，得到白砂糖處理物；將0.05份食鹽在105℃烘乾3小時，室溫冷卻後過16目篩，得到食鹽處理
物；在12℃將上述凍乾粉、白砂糖處理物、食鹽處理物、0.5份碳酸氫鈉及0.3份調味劑混合，得到補虛損保健品組合物固體飲料。
實施例5
本實施例的補虛損保健品組合物的製備過程如下：
(1)按照質量份數計，將40份蒲公英、120份蔥子、10份韭黃、16份菠蘿與椰子和火龍果的混合物、3份紅花子與紫蘇子和黃秋葵子的混合物及3份胡椒粉碎、混合，得到固體混合物。
(2)加入800ml的純化水到上述固體混合物中，升溫到75℃浸提90min，過濾得到浸提汁。
(3)將上述浸提汁在反滲透壓為100kg/cm2的壓力下，濃縮至相對密度為1.20的濃縮液。
(4)往上述濃縮液中加入3倍濃縮液體積的乙醇溶液(乙醇體積百分含量為75%)沉澱除雜，得到精製液。
(5)往上述精製液中加入3%的濃縮液體積的β-環糊精，攪拌混合進行包埋處理，得到提取液。
(6)將上述提取液在-50℃冷凍乾燥，製成補虛損保健品組合物凍乾粉。
(7)按照質量份數計，將3份冰糖，在60℃下烘乾12小時，粉碎後過60目篩，得到冰糖處理物；將0.2份食鹽在105℃烘乾3小時，室溫冷卻後過16目篩，得到食鹽處理物；在12℃將上述凍乾粉、冰糖處理物、食鹽處理物、0.5份碳酸
氫鈉及0.3份調味劑混合，得到補虛損保健品組合物固體飲料。
實施例6
本實施例的補虛損保健品組合物的製備過程如下：
(1)按照質量份數計，將40份蒲公英、10份蔥白、100份韭菜籽、9份雪蓮果與榴槤的混合物、3份燕麥與苦蕎麥和牡丹花子的混合物及6份香果粉碎、混合，得到固體混合物。
(2)加入800ml的純化水到上述固體混合物中，升溫到75℃浸提90min，過濾得到浸提汁。
(3)將上述浸提汁在反滲透壓為100kg/cm2的壓力下，濃縮至相對密度為1.20的濃縮液。
(4)往上述濃縮液中加入3倍濃縮液體積的乙醇溶液(乙醇體積百分含量為80%)沉澱除雜，得到精製液。
(5)往上述精製液中加入1.5%的濃縮液體積的多孔澱粉，攪拌混合進行包埋處理，得到提取液。
(6)將上述提取液在-60℃冷凍乾燥，製成補虛損保健品組合物凍乾粉。
(7)按照質量份數計，將3份紅糖，在60℃下烘乾12小時，粉碎後過60目篩，得到紅糖處理物；將0.3份食鹽在105℃烘乾3小時，室溫冷卻後過16目篩，得到食鹽處理物；在12℃將上述凍乾粉、紅糖處理物、食鹽處理物、0.5份碳酸氫鈉及0.2份調味劑混合，得到補虛損保健品組合物固體飲料。
實施例7
本實施例的補虛損保健品組合物的製備過程如下：
(1)按照質量份數計，將10份蒲公英、15份洋蔥、25份芹菜、8份諾麗果、6份茶籽金花菌、6份松花粉、6份桑椹子與百香果和山楂的混合物及3份花椒粉碎、混合，得到固體混合物。
(2)加入800ml的純化水到上述固體混合物中，升溫到80℃浸提120min，過濾得到浸提汁。
(3)將上述浸提汁在反滲透壓為100kg/cm2的壓力下，濃縮至相對密度為1.20的濃縮液。
(4)往上述濃縮液中加入3倍的濃縮液體積的乙醇溶液(乙醇體積百分含量為85%)沉澱除雜，得到精製液。
(5)往上述精製液中加入5%的濃縮液體積的多孔澱粉，攪拌混合進行包埋處理，得到提取液。
(6)將上述提取液在-35℃冷凍乾燥，製成補虛損保健品組合物凍乾粉。
(7)按照質量份數計，將4份果糖，在60℃下烘乾12小時，粉碎後過60目篩，得到果糖處理物；將0.15份食鹽在105℃烘乾3小時，室溫冷卻後過16目篩，得到食鹽處理物；在12℃將上述凍乾粉、果糖處理物、食鹽處理物、0.3份碳酸氫鈉及0.3份調味劑混合，得到補虛損保健品組合物固體飲料。
實施例8
本實施例的補虛損保健品組合物的製備過程如下：
(1)按照質量份數計，將5份蒲公英、10份蒜、30份韭白、6份五指果、6份茶籽金花菌、6份松花粉及3份核桃仁與杏仁和桃仁的混合物及6份丁香粉碎、混合，得到固體混合物。
(2)加入800ml的純化水到上述固體混合物中，升溫到80℃浸提60min，過濾得到浸提汁。
(3)將上述浸提汁在反滲透壓為100kg/cm2的壓力下，濃縮至相對密度為1.20的濃縮液。
(4)往上述濃縮液中加入3倍濃縮液體積的乙醇溶液(乙醇體積百分含量為96%)沉澱除雜，得到精製液。
(5)往上述精製液中加入5%的濃縮液體積的多孔澱粉，攪拌混合進行包埋處理，得到提取液。
(6)將上述提取液在-35℃冷凍乾燥，製成補虛損保健品組合物凍乾粉。
(7)按照質量份數計，將0.05份蛋白糖，在60℃下烘乾12小時，粉碎後過60目篩，得到蛋白糖處理物；將0.05份食鹽在105℃下烘乾3小時，室溫冷卻後過16目篩，得到食鹽處理物；在12℃下將上述凍乾粉、蛋白糖處理物、食鹽處理物、0.4份碳酸氫鈉及0.2份調味劑混合，得到補虛損保健品組合物固體飲料。
實施例9
本實施例的補虛損保健品組合物的製備過程如下：
(1)按照質量份數計，將5份蒲公英、25份漢蔥、
10份芫荽、8份榴槤、6份茶籽金花菌、6份松花粉、3份納豆與可可豆和咖啡豆的混合物及2份八角粉碎、混合，得到固體混合物。
(2)加入800ml的純化水到上述固體混合物中，升溫到80℃浸提60min，過濾得到浸提汁。
(3)將上述浸提汁在反滲透壓為100kg/cm2的壓力下，濃縮至相對密度為1.20的濃縮液。
(4)往上述濃縮液中加入3倍濃縮液體積的乙醇溶液(乙醇體積百分含量為75%)沉澱除雜，得到精製液。
(5)往上述精製液中加入6%的濃縮液體積的多孔澱粉，攪拌混合進行包埋處理，得到提取液。
(6)將上述提取液在-35℃冷凍乾燥，製成補虛損保健品組合物凍乾粉。
(7)按照質量份數計，將0.01份甜菊糖，在60℃下烘乾12小時，粉碎後過60目篩，得到甜菊糖處理物；將0.02份食鹽在105℃烘乾3小時，室溫冷卻後過16目篩，得到食鹽處理物；在12℃將上述凍乾粉、甜菊糖處理物、食鹽處理物、0.3份碳酸氫鈉及0.3份調味劑混合，得到補虛損保健品組合物固體飲料。
測試部分：
將實施例和中藥參茸三鞭粉劑、喜得康粉劑進行如下臨床試驗：
1．實驗物件資料
所有觀察物件為臨床確診為腎虛的亞健康人群共36例，均為男性，年齡最小21歲，最大66歲，平均年齡44歲。
將亞健康人群分為三組，每組12人，分別命名為組1~3，利用SPSS統計軟體對3個組年齡，中醫症狀記分比較，P>0.05，差異無統計學意義，說明這3組具有可比性。
2．實驗物件的選擇標準
2.1病例納入標準
(1)臨床確診的亞健康人群；(2)年齡18~75周歲；(3)簽署知情同意書。
2.2病例排除標準
(1)有過敏史者；(2)伴有肝、腎、造血系統及心、腦血管等原發性疾病以及精神病患者；(3)肝功能異常者；(4)有其他臟器病變者。
3．實驗方法
組1的亞健康人群分別服用由實施例1製備的本發明的組合物得到的固體粉劑，組2和組3分別服用由對比1、對比2製備的中藥參茸三鞭粉劑及喜得康粉劑，一次15g，一天兩次，檢查並記錄實驗者的身體反應。
4．中醫證候療效評定標準
將腎虛精虧、氣血兩虛、失眠、健忘、腰腿酸軟、眩暈耳鳴等症狀分為無、輕、重三個等級，對應的分值為0、2、4分，服用20天後對觀察者進行評分。
療效指數(n)=[(治療前分值-治療後分值)÷治療前分值]×100%
顯效：證候中上述症狀大部分消失，有效率n
70%；有效：證候中上述症狀基本消失，有效率30%n
n<70%；無效：證候中上述症狀有一定改善，有效率n<30%；有效率=[顯效例數+有效例數/總例數]×100%。
5．實驗結果
從表1的結果可知，本發明製備的補虛損保健品組合物對腎虛所致的虛損的亞健康狀態具有良好的補虛損，補腎壯陽的功效，有效率達91.66%。
6．病例回饋
病例1：周某，男，60歲，近一年來體弱多病，體質虛弱，全身不適，易疲乏，稍幹點活兒就累，出現心慌，腿無力，時伴有耳鳴，服用本組合物液體飲料6瓶，感覺精神見好，疲勞減輕，身體較舒服。服用一個療程共20天，體質改善，所見症狀恢復，精神飽滿，精力旺盛，體力恢復正常。
病例2：張某，男，24歲，與女友相識半年，性生活不如意，勃起疲軟，伴有早洩症狀，戀愛前有手淫史，服用本組合物粉劑，一個療程，性功能恢復，與女友性生活持續約40分鐘，性要求強烈。
病例3：朱某，男，29歲，性欲減退，夜尿頻多，伴疲乏無力，服本組合物粉劑，服1瓶後即有性衝動，連喝5~6瓶，勃起堅挺，夜尿明顯減少，且思考能力明顯提升，一星期都如此，運動反應比以前靈敏、快捷，夜間工作不感到疲倦，尤其性生活旺盛，房事後無疲勞感。
綜上，上述補虛損保健品組合物至少具有以下有益效果：(1)製備上述補虛損保健品組合物所需的原料為日常生活中常用的蔬菜、水果以及食用種子等，故上述補虛損保健品組合物不含性激素，且無明顯的毒副作用；(2)上述補虛損保健品組合物經臨床試驗證實具有良好的補虛損，補腎壯陽的效果。
以上實施例的各技術特徵可以進行任意的組合，為使描述簡潔，未對上述實施例中的各個技術特徵所有可能的組合都進行描述，然而，只要這些技術特徵的組合不存在矛盾，都應當認為是本說明書記載的範圍。
以上實施例僅表達了本申請的幾種實施方式，其描述較為具體和詳細，但並不能因此而理解為對發明專利範圍的限制。應當指出的是，對於本領域的普通技術人員來說，在不脫離本申請構思的前提下，還可以做出若干變形和改進，這些都屬於本申請的保護範圍。因此，本申請專利的保護範圍應以所附申請專利範圍為准。
S110~S170‧‧‧步驟
Claims (10)
- 一種補虛損保健品組合物，其特徵在於，按照質量份數計，製備該補虛損保健品組合物的原料包括：蒲公英5份~40份、鱗莖菜類10份~120份、香辛葉菜類10份~100份、水果8份~16份；其中，該鱗莖菜類選自蔥、洋蔥及蒜中至少一種，該香辛葉菜類選自韭菜、芹菜及芫荽中至少一種，該水果選自葡萄、藍莓、黑加侖、檸檬、橘子、橙子、荔枝、櫻桃、龍眼肉、草莓、菠蘿、椰子、火龍果、雪蓮果，榴槤、諾麗果、五指果及番茄中至少一種。
- 如申請專利範圍第1項所述之補虛損保健品組合物，其中按照質量份數計，製備該補虛損保健品組合物的原料還包括0份~6份的食用種子，該食用種子選自枸杞子、余甘子、沙棘子、燕麥、苦蕎麥、納豆、桑椹子、核桃仁、芝麻、牡丹花子、百香果、杏仁、桃仁、紅花子、紫蘇子、南瓜子、苦瓜籽、松籽、辣木籽、瑪卡籽、黃秋葵子、山楂、可可豆及咖啡豆中至少一種。
- 如申請專利範圍第1項所述之補虛損保健品組合物，其中按照質量份數計，製備該補虛損保健品組合物的原料還包括0份~6份的茶籽金花菌和0份~6份的松花粉。
- 如申請專利範圍第1項所述之補虛損保健品組合物，其中按照質量份數計，製備該補虛損保健品組合物的原料還包括0份~6份的香辛料，該香辛料選自薑、肉桂、茴香、八角、胡椒、香果、花椒及丁香中至少一種。
- 如申請專利範圍第1至4項中任一項所述之補虛損保健品組 合物在製備保健藥物、保健飲料或巧克力中的應用。
- 一種如申請專利範圍第1至4項中任一項所述之補虛損保健品組合物的製備方法，包括如下步驟：將製備該補虛損保健品組合物的原料粉碎、混合，然後在純化水中70℃~80℃下進行浸提處理，得到浸提汁。
- 如申請專利範圍第6項所述之補虛損保健品組合物的製備方法，其中在該浸提處理的步驟之後還包括如下步驟：將該浸提汁進行濃縮處理至相對密度為1.18~1.20，得到濃縮液；加入0.3%~6%的濃縮液體積的包埋劑進行包埋處理，得到提取液。
- 如申請專利範圍第7項所述之補虛損保健品組合物的製備方法，其中該濃縮處理時的反滲透壓為30kg/cm2~150kg/cm2，該包埋劑為β-環糊精或多孔澱粉。
- 如申請專利範圍第7項所述之補虛損保健品組合物的製備方法，其中在該濃縮處理的步驟之後，該包埋處理的步驟之前，還包括加入3倍濃縮液體積的乙醇溶液沉澱除雜得到精製液的步驟，該乙醇溶液中乙醇的體積百分含量高於70%。
- 如申請專利範圍第7項所述之補虛損保健品組合物的製備方法，其中在該包埋處理的步驟之後還包括在-70℃~-35℃的溫度下，將該提取液冷凍乾燥製成凍乾粉的步驟。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HK18112945 | 2018-10-10 | ||
| HK18112945.1 | 2018-10-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW202027617A true TW202027617A (zh) | 2020-08-01 |
| TWI732309B TWI732309B (zh) | 2021-07-01 |
Family
ID=70164471
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW108136499A TWI732309B (zh) | 2018-10-10 | 2019-10-09 | 補虛損保健品組合物及其製備方法和其應用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20210228667A1 (zh) |
| EP (1) | EP3864969A4 (zh) |
| JP (1) | JP7199518B2 (zh) |
| KR (1) | KR20210057122A (zh) |
| AU (1) | AU2019357838A1 (zh) |
| CA (1) | CA3115743A1 (zh) |
| SG (1) | SG11202103646UA (zh) |
| TW (1) | TWI732309B (zh) |
| WO (1) | WO2020073922A1 (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116392527A (zh) * | 2023-03-10 | 2023-07-07 | 山东宏济堂制药集团股份有限公司 | 一种用于改善慢性肾脏病的药食同源产品 |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102379258B1 (ko) * | 2021-08-17 | 2022-03-29 | 재단법인 포항테크노파크 | 햄프씨드를 함유하는 건강기능 식품 및 그 제조방법 |
| KR102619906B1 (ko) | 2023-06-16 | 2023-12-29 | 정인영 | 한방 발효 조성물을 첨가한 흑염소 진액의 최적의 배합비 |
| KR102619904B1 (ko) | 2023-06-16 | 2023-12-29 | 정인영 | 면역개선 및 기력증진용 흑염소 한방 발효조성물의 제조방법 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1291127B1 (it) * | 1997-04-01 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Integratore alimentare per soggetti dediti ad intensa e prolungata attivita' fisica |
| IT1299161B1 (it) * | 1998-04-17 | 2000-02-29 | Sigma Tau Healthscience Spa | Composizione comprendente l-carnitina o un'alcanoil l-carnitina e nadh e/o nadph |
| CN101467623A (zh) * | 2007-12-25 | 2009-07-01 | 刘泳宏 | 一种天然五色健美豆腐制品及加工方法 |
| JP2011087566A (ja) * | 2009-10-26 | 2011-05-06 | Shinzo Matsui | ゴーヤの種子粉末を配合した健康増進剤 |
| KR101040682B1 (ko) * | 2010-11-04 | 2011-06-10 | 김병주 | 면역력이 강화된 조성물의 제조방법 및 그에 따른 조성물 |
| CN104096015A (zh) * | 2012-01-05 | 2014-10-15 | 谢有珠 | 芦荟有病能治无病能防植物性中草药与皮肤吸收水药和食疗 |
| CN103622002A (zh) * | 2012-08-29 | 2014-03-12 | 浙江劲膳美生物科技有限公司 | 改善贫血食疗配餐或代餐品 |
| CN103960562A (zh) * | 2014-05-26 | 2014-08-06 | 通化长城药业股份有限公司 | 松花粉片 |
| KR101775613B1 (ko) * | 2014-09-16 | 2017-09-07 | 주식회사 메디바이오랩 | 망고스틴 추출물 또는 알파, 감마 망고스틴을 유효성분으로 포함하는 치주질환 예방 또는 개선용 조성물 |
| WO2016093104A1 (ja) * | 2014-12-09 | 2016-06-16 | 株式会社日本自然発酵 | 老化抑制剤 |
| JP6569994B2 (ja) * | 2015-03-30 | 2019-09-04 | 株式会社富士見養蜂園 | 蜂産物エキスの製造方法及び蜂産物エキス |
| KR101578070B1 (ko) * | 2015-04-08 | 2015-12-16 | 김경일 | 발모 촉진, 탈모 완화 및 개선, 혈당 조절, 위장 장애 증상 완화 및 개선용 건강보조식품 |
| CN105614718A (zh) * | 2015-12-25 | 2016-06-01 | 绍兴文理学院 | 一种适用于糖尿病人的乌发美容养颜药膳及其制备方法 |
| CN107683929B (zh) * | 2016-08-05 | 2021-04-09 | 四川师范大学 | 金花菌对栘*叶化学成分的微生物转化及应用 |
| CN108567820B (zh) * | 2017-03-13 | 2021-07-09 | 左安刚 | 一种用于肿瘤治疗的中药组合物及其制备方法 |
| CN108308614A (zh) * | 2018-03-23 | 2018-07-24 | 杨伏文 | 一种均衡营养细胞、调理五脏功能的保健食品及其制备方法 |
-
2019
- 2019-10-09 EP EP19872050.0A patent/EP3864969A4/en not_active Withdrawn
- 2019-10-09 JP JP2021516576A patent/JP7199518B2/ja active Active
- 2019-10-09 CA CA3115743A patent/CA3115743A1/en active Pending
- 2019-10-09 WO PCT/CN2019/110142 patent/WO2020073922A1/zh unknown
- 2019-10-09 AU AU2019357838A patent/AU2019357838A1/en not_active Abandoned
- 2019-10-09 SG SG11202103646UA patent/SG11202103646UA/en unknown
- 2019-10-09 TW TW108136499A patent/TWI732309B/zh not_active IP Right Cessation
- 2019-10-09 KR KR1020217010628A patent/KR20210057122A/ko not_active Application Discontinuation
-
2021
- 2021-04-11 US US17/227,370 patent/US20210228667A1/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116392527A (zh) * | 2023-03-10 | 2023-07-07 | 山东宏济堂制药集团股份有限公司 | 一种用于改善慢性肾脏病的药食同源产品 |
| CN116392527B (zh) * | 2023-03-10 | 2024-02-13 | 山东宏济堂制药集团股份有限公司 | 一种用于改善慢性肾脏病的制剂 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020073922A1 (zh) | 2020-04-16 |
| JP7199518B2 (ja) | 2023-01-05 |
| EP3864969A4 (en) | 2022-06-15 |
| SG11202103646UA (en) | 2021-05-28 |
| KR20210057122A (ko) | 2021-05-20 |
| AU2019357838A1 (en) | 2021-04-15 |
| EP3864969A1 (en) | 2021-08-18 |
| US20210228667A1 (en) | 2021-07-29 |
| TWI732309B (zh) | 2021-07-01 |
| JP2022501387A (ja) | 2022-01-06 |
| CA3115743A1 (en) | 2020-04-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TWI732309B (zh) | 補虛損保健品組合物及其製備方法和其應用 | |
| Shankar et al. | Brahmi (Bacopa monnieri) as functional food ingredient in food processing industry | |
| JP2006504790A (ja) | マンゴスチン栄養補給組成物 | |
| CN104323281B (zh) | 松花和茯苓的含水组合物及其制备方法和应用 | |
| WO2014131344A1 (zh) | 一种饮料 | |
| CN111264735A (zh) | 一种扶正固本提高免疫力防控疫毒的功能饮料 | |
| CN103653085A (zh) | 一种滋阴补肾药膳猪骨汤 | |
| CN111375049B (zh) | 一种解酒保肝的组合物及其制备方法和应用 | |
| CN111110792A (zh) | 一种控糖调脂降粘防治糖尿病及其并发症的黄精人参茶 | |
| KR101483255B1 (ko) | 총백을 이용한 기능성 한방차 및 그 제조방법 | |
| Kandasamy et al. | Medicinal and nutritional characteristics of fruits in human health | |
| CN109077167A (zh) | 一种祛湿茶及其制备方法 | |
| KR20100077781A (ko) | 발기부전에 효과적인 기능성 분말의 제조 방법, 이에 의한 기능성 분말을 포함하는 기능성 보조식품 | |
| KR101999675B1 (ko) | 관상동맥성 심장질환의 예방과 치료용 생약조성물 | |
| CN103920065B (zh) | 一种抗衰老的中药组合物 | |
| RU2333677C2 (ru) | Биологически активная добавка | |
| Ashok et al. | Nutraceutical values of minor fruits on immunity development to combat diseases | |
| KR102353626B1 (ko) | 젤리 타입 녹용음료 및 이의 제조방법 | |
| KR20130029284A (ko) | 치매 개선용 건강식품 조성물 | |
| CN111035007A (zh) | 补虚损保健品组合物及其制备方法和其应用 | |
| CN107594252A (zh) | 一种葡萄汁保健饮品及其制备方法 | |
| RU2792449C2 (ru) | Состав фиточая, содержащего биологически активные добавки | |
| HS et al. | Nutraceutical and medicinal values of minor fruits in Western Ghats of South India | |
| Ye et al. | Traditional Chinese dates (Jujubes)-based functional foods in Chinese history | |
| CN109170052A (zh) | 一种石斛养胃保健茶及其制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Annulment or lapse of patent due to non-payment of fees |